Madu_00050 : CDS information

Location

Organism	Actinomadura madurae
Strain	ATCC 39144
Entry name	Maduropeptin
Contig	AY271660
Start / Stop / Direction	11,790 / 12,206 / + [in whole cluster] 11,790 / 12,206 / + [in contig]
Location	11790..12206 [in whole cluster] 11790..12206 [in contig]
Type	CDS
Length	417 bp (138 aa)

Annotation

Category	5.4 hypothetical protein
Product	hypothetical protein
Product (GenBank)	glyoxylase/dioxygenase superfamily
Gene
Gene (GenBank)
EC number
Keyword
Note	It is supposed that this ORF is not involved in maduropeptin biosynthesis.
Note (GenBank)	mdp orf-1
Reference	ACC B0BLL4 PmId [17918933] Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis. (J Am Chem Soc. , 2007) comment Maduropeptin生合成遺伝子クラスターの報告 orf(-1): Glyoxylase/dioxygenase superfamily Maduropeptin生合成遺伝子クラスターは、遺伝子産物の推定機能よりmdpA1からmdpE2までとしている。このORFについて機能解析はしていない。

Sequence

>hypothetical protein [glyoxylase/dioxygenase superfamily]
MNWTLEVVCLPVTDLDRSLAFYSEGLGFNVDIDTVRPDGKRMIQVTPPGSGCSVMLGADM
NDMPPGSMRGLQLVVRDILAAHAELTERGVKVGEVQVFTQDGSMRAYQDGDWLDNTGFLF
FDDPDGNSWAVQQISARD

>hypothetical protein [glyoxylase/dioxygenase superfamily]
ATGAATTGGACGCTCGAGGTCGTCTGCCTTCCGGTCACCGACCTGGACCGCTCCCTCGCC
TTCTACTCCGAGGGGCTCGGCTTCAACGTCGACATCGACACCGTGCGCCCCGACGGGAAG
CGCATGATCCAGGTGACCCCGCCCGGGTCCGGCTGCTCCGTCATGCTGGGCGCCGACATG
AACGACATGCCGCCGGGGTCGATGCGCGGCCTGCAGCTCGTCGTCCGCGACATCCTCGCC
GCCCACGCCGAGCTCACCGAGCGCGGCGTGAAGGTCGGCGAGGTGCAGGTCTTCACGCAG
GACGGCAGCATGCGCGCCTACCAGGACGGCGACTGGCTCGACAACACCGGCTTCCTCTTC
TTCGACGACCCGGACGGCAACAGCTGGGCCGTCCAGCAGATCAGCGCCCGGGACTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR025870 Glyoxalase-like domain (Domain) PF12681 Glyoxalase_2
SignalP	No significant hit
TMHMM	No significant hit

Madu_00040 Madu_00060