Calm_00070 Calm_00070   Calm_00090 Calm_00090

Calm_00080 : CDS information

close this sectionLocation

Organism
StrainNRRL 15839
Entry nameCalicheamicin
Contig
Start / Stop / Direction8,285 / 7,665 / - [in whole cluster]
8,285 / 7,665 / - [in contig]
Locationcomplement(7665..8285) [in whole cluster]
complement(7665..8285) [in contig]
TypeCDS
Length621 bp (206 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category4.1 transcriptional regulator
Productputative TetR family transcriptional regulator
Product (GenBank)CalR1
Gene
Gene (GenBank)calR1
EC number
Keyword
Note
Note (GenBank)
Reference
ACC
PmId
[12183629] The calicheamicin gene cluster and its iterative type I enediyne PKS. (Science. , 2002)
comment
calicheamicin生合成遺伝子クラスターの報告

このORFは、Fig2の生合成clusterにて、putative regulatory elements(R1 to R9)として示されているのみ。本文中では特にふれていない。
Related Reference
ACC
P39885
PmId
[1592820] The Streptomyces glaucescens TcmR protein represses transcription of the divergently oriented tcmR and tcmA genes by binding to an intergenic operator region. (J Bacteriol. , 1992)
comment
Streptomyces glaucescens_tcmR
HTH-type transcriptional regulator tcmR
(Tetracenomycin C transcriptional repressor)

tcmRありなしでのtcmAへの影響、TcmR proteinの結合条件を検討している。TcmR proteinはtcmA と tcmRの転写を阻害するrepressorとして機能する。

close this sectionSequence

selected fasta
>putative TetR family transcriptional regulator [CalR1]
MHTGETESAPGRRDRRKRRTRAALTGAALRLVAERGLAQVTVEEISEAAGVSPRTFFNYF
ACKDDALVGDHAGDAARLVARLAAVPPEVPVLTALRAALDEVIDEVRTERELWCLRMEVV
TRNPVLLPRLVAGNVETERAIAEVVAARVGVDPDHGYPALVTAVAGAAVRTAMTRWAAHP
DGPDLADLVDEAFAALAAGLPQPDPT
selected fasta
>putative TetR family transcriptional regulator [CalR1]
GTGCACACCGGCGAGACCGAATCCGCCCCCGGGCGACGCGACCGCAGGAAGCGCCGGACC
CGGGCCGCGCTGACCGGGGCGGCGCTGCGCCTGGTGGCTGAGCGCGGCCTGGCCCAGGTG
ACGGTGGAGGAGATCAGCGAGGCGGCCGGCGTCTCCCCGCGTACCTTCTTCAACTACTTC
GCCTGCAAGGACGACGCGCTGGTCGGCGACCACGCGGGCGACGCGGCGCGGCTGGTCGCG
CGCCTGGCGGCCGTGCCGCCGGAGGTGCCGGTGCTGACCGCGCTGCGGGCCGCGCTCGAC
GAGGTGATCGACGAGGTGCGCACCGAGCGCGAGCTGTGGTGCCTGCGGATGGAGGTGGTG
ACGCGCAACCCGGTGTTGCTGCCCCGTCTGGTCGCCGGCAACGTCGAGACCGAGCGGGCC
ATCGCCGAGGTCGTCGCGGCGCGGGTCGGGGTCGATCCCGACCACGGCTACCCGGCACTC
GTCACCGCCGTGGCCGGGGCGGCGGTGCGAACCGCGATGACCCGGTGGGCCGCACATCCC
GACGGACCGGACCTGGCCGACCTCGTCGACGAGGCGTTCGCCGCGCTCGCCGCGGGTCTG
CCGCAGCCCGACCCGACCTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR001647 DNA-binding HTH domain, TetR-type (Domain)
[26-65] 1.1e-11 PF00440
PF00440   TetR_N
[18-78] PS50977
PS50977   HTH_TETR_2
[24-37] 1.19999985703101e-05 PR00455 [45-68] 1.19999985703101e-05 PR00455
PR00455   HTHTETR
IPR009057 Homeodomain-like (Domain)
[12-64] 1.99999999999999e-17 G3DSA:1.10.10.60
G3DSA:1.10.10.60   Homeodomain-rel
[13-88] 6.49999377884395e-15 SSF46689
SSF46689   Homeodomain_like
IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal (Domain)
[65-201] 1.70000000000001e-39 G3DSA:1.10.357.10
G3DSA:1.10.357.10   TetR_C
SignalP No significant hit
TMHMM No significant hit
Calm_00070 Calm_00070   Calm_00090 Calm_00090
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