Dynm_00390 : CDS information

Location

Organism	Micromonospora chersina
Strain	ATCC 53710 (=NBRC 15963)
Entry name	Dynemicin
Contig	EF552206
Start / Stop / Direction	53,635 / 52,523 / - [in whole cluster] 53,635 / 52,523 / - [in contig]
Location	complement(52523..53635) [in whole cluster] complement(52523..53635) [in contig]
Type	CDS
Length	1,113 bp (370 aa)

Annotation

Category	5.4 hypothetical protein
Product	hypothetical protein
Product (GenBank)	putative methyltransferase
Gene	dynA5
Gene (GenBank)
EC number
Keyword
Note
Note (GenBank)	ORF28
Reference	ACC B2BM54 PmId [18328078] The biosynthetic genes encoding for the production of the dynemicin enediyne core in Micromonospora chersina ATCC53710. (FEMS Microbiol Lett. , 2008) comment Dynemicin生合成遺伝子クラスターの報告。 dynA5 Putative hydroxylase genbank: orf28 homologyから機能推測している。maturation or fusionに関与すると推測されているが、機能解析はされていない。

Sequence

>hypothetical protein [putative methyltransferase]
MNQPTLTSEAQQPPGPPGQLDMSALMAFMQRFVGDVSAAGVVVMCALGSRLGLFADLARS
GPATAGELARRTGNHERYVREWALALASAAYLTRDAEGRYALPPGPAAALGDENGPFYMG
DMAQLVPALSAVLDGVIEGFRTGSGLHPEEYPAELFETIWHKDANRLGKVLVPQWVVAVD
GLTEQLTVGGRVAQVHCGDGRALILLAQAFPKLELVGYDPVEINVRRARAEAAAAGVADR
IRFSTADPAEDLDGGLALVLAIDVLHEAPDPAALLRRIHDSLQSHGVFLLLATNGEDVPL
AGAGPVSSMLYAISTLQHVPQGLAAGAADPAGLMGLPPALLHRLCEEAGFTTVEKLMEPS
PFNTLYELRA

>hypothetical protein [putative methyltransferase]
GTGAACCAGCCCACCCTGACCTCCGAAGCCCAGCAGCCGCCCGGCCCGCCGGGGCAGTTG
GACATGTCCGCGCTGATGGCCTTCATGCAGCGTTTCGTCGGCGACGTGTCGGCGGCCGGC
GTGGTCGTCATGTGCGCCCTCGGCAGCCGGCTCGGCCTCTTCGCCGACCTGGCCCGCTCG
GGGCCGGCCACCGCCGGGGAACTCGCCCGCCGCACCGGCAACCACGAGCGGTACGTCCGC
GAGTGGGCGCTGGCCCTGGCCAGCGCCGCCTACCTCACCCGGGACGCCGAGGGCCGGTAC
GCCCTGCCGCCCGGCCCGGCCGCCGCCCTCGGTGACGAGAACGGGCCGTTCTACATGGGG
GACATGGCCCAGCTCGTGCCCGCGCTGTCGGCGGTGCTGGACGGTGTGATCGAGGGCTTC
CGCACCGGCTCCGGGCTGCACCCCGAGGAGTACCCGGCGGAGCTGTTCGAGACCATCTGG
CACAAGGACGCCAACCGCCTCGGCAAGGTGCTCGTCCCGCAGTGGGTGGTCGCGGTGGAC
GGGCTCACCGAGCAGCTCACCGTCGGCGGGCGGGTGGCGCAGGTGCACTGCGGCGACGGC
CGGGCGCTGATCCTGCTCGCCCAGGCCTTCCCGAAGCTCGAACTCGTCGGATACGACCCA
GTCGAGATCAACGTCCGCCGGGCCCGCGCCGAGGCGGCGGCGGCCGGCGTGGCGGACCGG
ATCCGGTTCAGCACCGCCGACCCGGCCGAGGACCTCGACGGCGGGCTGGCGCTCGTGCTG
GCGATCGACGTGCTGCACGAGGCGCCCGACCCGGCCGCGCTGCTGCGCCGCATCCACGAC
TCCCTCCAGTCGCACGGGGTGTTCCTGCTGCTGGCCACCAACGGCGAGGACGTGCCGCTG
GCCGGCGCCGGCCCGGTGAGCAGCATGCTCTACGCGATCAGCACCCTCCAGCACGTGCCG
CAGGGCCTCGCGGCCGGCGCCGCCGACCCGGCCGGACTGATGGGGCTGCCGCCGGCGCTG
CTGCACCGGCTGTGCGAGGAGGCCGGCTTCACGACCGTCGAGAAGCTGATGGAGCCCAGC
CCGTTCAACACCCTCTACGAGCTCCGGGCCTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR011991 Winged helix-turn-helix transcription repressor DNA-binding (Domain) G3DSA:1.10.10.10 Wing_hlx_DNA_bd
SignalP	No significant hit
TMHMM	No significant hit

Dynm_00380 Dynm_00400