遺伝子 : Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE (ARNE)

遺伝子情報

ID	NRULE_0136
遺伝子ID	ARNE
作成日	2013/02/12
タンパク質名	Protein name Full Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE Short L-Ara4N-phosphoundecaprenol flippase subunit ArnE Synonym Full Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE
遺伝子名	arnE
遺伝子条件	HAMAP; MF_01869; hit=1
参照	Gene Ontology GO GO:0022891, F:substrate-specific transmembrane transporter activity, IMP:EcoCyc GO:0009245, P:lipid A biosynthetic process, IEA:UniProtKB-KW GO:0009103, P:lipopolysaccharide biosynthetic process, IEA:UniProtKB-UniPathway GO:0010041, P:response to iron(III) ion, IGI:EcoCyc Phylogenomic databases KO K12962, - Family and domain databases HAMAP MF_01869, Flippase_ArnE, 1, - InterPro IPR000620, DMT IPR022883, Flippase_ArnE Pfam PF00892, EamA, 1
配列の特徴	該当データなし
注釈	Function Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) Pathway Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis Subunit structure Heterodimer of ArnE and ArnF (By similarity) Subcellular location Cell inner membrane; Multi-pass membrane protein (By similarity) Sequence similarities Belongs to the ArnE family
参考文献	Q47377 Escherichia coli (strain K12). 17928292 An undecaprenyl phosphate-aminoarabinose flippase required for polymyxin resistance in Escherichia coli. (J Biol Chem. 2007)

関与する機能

機能名
Polymyxin resistance

該当CDS

学名	NBRC番号	CDS	タンパク質名
Edwardsiella tarda	105688	ET1_02_00820	putative 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE
Enterobacter aerogenes	13534	EAE_05675	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE
Enterobacter cloacae subsp. cloacae	13535	ECL_04858	hypothetical protein
Escherichia coli	3972	EcolC_1391	small multidrug resistance protein
Escherichia coli	13500	WFL_11985	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE
Escherichia coli	12713	Y75_2261	conserved hypothetical protein
Escherichia fergusonii	102419	EFER_0911	conserved hypothetical protein; inner membrane protein
Klebsiella pneumoniae	14438	KPR_5075
Klebsiella pneumoniae subsp. rhinoscleromatis	105682	HMPREF0484_0799	multidrug resistance protein, SMR family
Proteus mirabilis	105697	HMPREF0693_0621	multidrug resistance protein, SMR family
Providencia alcalifaciens	105687	PROVALCAL_02526	multidrug resistance protein, SMR family
Serratia odorifera	102598	HMPREF0758_3966	hypothetical protein
Shimwellia blattae	105725	EB105725_04_02110	putative 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE
Yersinia rohdei	105715	yrohd0001_27800	hypothetical protein