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機能 : Naphthalene degradation (via hydroxylation by dioxygenase)

機能情報

ID NFUNC_0067
作成日 2013/04/17
説明 Naphthalene is catabolized through cis-dihydrodiol naphthalene, salicylaldehyde, and salicylate. The latter is converted into either catechol (by 1-hydroxylase), which is then degraded by either the meta or the ortho cleavage pathways to TCA cycle intermediates, or to gentisate (by 5-hydroxylase), which is degraded by a different pathway to TCA cycle intermediates.
コメント
Subunit structure
The ring-hydroxylating dioxygenase multicomponent enzyme system composed of the hydroxylase component (two subunits) and the electron transfer component (ferredoxin and ferredoxin reductase)
The salicylate 5-hydroxylase multicomponent enzyme system is composed of the hydroxylase component (NagG and NagH) and the electron transfer component (ferredoxin and ferredoxin reductase)
参照 UniPathway UPA00082
UM-BBD Naphthalene Pathway Map
KEGG Pathway Naphthalene degradation

機能構成

タイプパターン 構成遺伝子
Naphthalene degradation (via hydroxylation by dioxygenase)(NFUNC_0067)
必須A
RHDA
(NRULE_0048)
Ring-hydroxylating dioxygenase alpha subunit
RHDB
(NRULE_0049)
Ring-hydroxylating dioxygenase beta subunit
CDDH
(NRULE_0056)
Cis-dihydrodiol dehydrogenase
EDIO
(NRULE_0058)
extradiol dioxygenase
NAHD
(NRULE_0171)
2-hydroxychromene-2-carboxylate isomerase
NAHE
(NRULE_0172)
Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase
NAHF
(NRULE_0173)
Salicylaldehyde dehydrogenase
NAHG
(NRULE_0190)
Salicylate hydroxylase
B
RHDA
(NRULE_0048)
Ring-hydroxylating dioxygenase alpha subunit
RHDB
(NRULE_0049)
Ring-hydroxylating dioxygenase beta subunit
CDDH
(NRULE_0056)
Cis-dihydrodiol dehydrogenase
EDIO
(NRULE_0058)
extradiol dioxygenase
NAHD
(NRULE_0171)
2-hydroxychromene-2-carboxylate isomerase
NAHE
(NRULE_0172)
Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase
NAHF
(NRULE_0173)
Salicylaldehyde dehydrogenase
NAGG
(NRULE_0191)
Salicylate 5-hydroxylase alpha subunit
NAGH
(NRULE_0192)
Salicylate 5-hydroxylase beta subunit
任意 
FDR1
(NRULE_0032)
Oxygenase electron transfer component
 
FDX1
(NRULE_0034)
Putative Rieske-type ferredoxin
 
FDR2
(NRULE_0057)
Ferredoxin reductase

機能が推定される微生物

学名NBRC番号