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遺伝子 : Ferredoxin reductase (FDR2)

遺伝子情報

ID NRULE_0057
遺伝子ID FDR2
作成日 2012/10/05
タンパク質名
Protein name
Full
Ferredoxin reductase
EC
EC 1.18.1.3
遺伝子名 該当データなし
遺伝子条件 HAMAP; MF_01651; hit=1
OR
BLASTP; A5W4E9; hit=1; score=400; pid=28
参照
Gene Ontology
GO
GO:0005737, C:cytoplasm, IEA:InterPro
GO:0008860, F:ferredoxin-NAD+ reductase activity, IEA:EC
GO:0050660, F:flavin adenine dinucleotide binding, IEA:InterPro
GO:0045454, P:cell redox homeostasis, IEA:InterPro
Phylogenomic databases
eggNOG
COG0446, -
HOGENOM
HOG000276711, -
KO
K00529, -
Family and domain databases
InterPro
IPR016156, FAD/NAD-linked_Rdtase_dimer
IPR013027, FAD_pyr_nucl-diS_OxRdtase
IPR004099, Pyr_nucl-diS_OxRdtase_dimer
IPR023753, Pyr_nucl-diS_OxRdtase_FAD/NAD
IPR001327, Pyr_OxRdtase_NAD-bd_dom
IPR028202, Reductase_C.
Pfam
PF00070, Pyr_redox, 1
PF07992, Pyr_redox_2, 1
PF14759, Reductase_C, 1
PRINTS
PR00368, FADPNR
配列の特徴 該当データなし
注釈
Function
Part of the electron transfer component of ring-hydroxylating dioxygenase and/or multicomponent monooxygenase system, transferselectrons from ferredoxin to NADH
Catalytic activity
Reduced ferredoxin + NAD(+) = oxidized ferredoxin + NADH
Cofactor
FAD
Subunit structure
The ring-hydroxylating dioxygenase system consists of three components: the hydroxylase component (two subunits), a ferredoxin and a ferredoxin reductase
The multicomponent monooxygenase system consists of three components: the oxygenase component (two or three subunits), a ferredoxin and a ferredoxin reductase. Aromatic compound metabolism. Hydrocarbonmetabolism; alkane degradation.
Sequence similarities
Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family
参考文献
P20372 Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1).
2298704
DNA sequences of genes encoding Acinetobacter calcoaceticus protocatechuate 3,4-dioxygenase: evidence indicating shuffling of genes and of DNA sequences within genes during their evolutionary divergence. (J Bacteriol. 1990)
P00437 Pseudomonas putida (Arthrobacter siderocapsulatus).
9254600
Crystal structures of substrate and substrate analog complexes of protocatechuate 3,4-dioxygenase: endogenous Fe3+ ligand displacement in response to substrate binding. (Biochemistry. 1997)
Q0SH27 Rhodococcus jostii (strain RHA1).
25558786
In vitro reconstitution of the catabolic reactions catalyzed by PcaHG, PcaB, and PcaL: the protocatechuate branch of the beta-ketoadipate pathway in Rhodococcus jostii RHA1. (Biosci Biotechnol Biochem. 2015)
Q9ZFA1 Streptomyces sp. 2065.
10742233
Characterization of the protocatechuic acid catabolic gene cluster from Streptomyces sp. strain 2065. (Appl Environ Microbiol. 2000)
P17052 Pseudomonas oleovorans.
9799514
Electron transfer from flavin to iron in the Pseudomonas oleovorans rubredoxin reductase-rubredoxin electron transfer complex. (Biochemistry. 1998)



関与する機能

機能名
Aniline degradation (conversion into catechol)
Anthranilate degradation (via hydroxylation)
Aromatic hydrocarbon degradation (via hydroxylation by dioxygenase)
Benzoate degradation (via hydroxylation by dioxygenase)
Naphthalene degradation (via hydroxylation by dioxygenase)
Phenol degradation

該当CDS

データダウンロード
学名 NBRC番号 CDS タンパク質名
Acidiphilium multivorum100883ACMV_P1_01400ferredoxin reductase
Acinetobacter radioresistens102413ACRAD_64_00120putative ferredoxin reductase
Acinetobacter sp.100985ACT4_067_00160putative ferredoxin reductase
Actinomadura atramentaria14695G339_09430hypothetical protein
G339_31160hypothetical protein
Actinosynnema mirum14064Amir_2893FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Amycolatopsis mediterranei13415RAM_02005ferredoxin--NAD+ reductase
RAM_09290ferredoxin reductase
RAM_22320ferredoxin reductase
Aquimarina agarilytica107695AagaZ_020100002359putative ferredoxin reductase
Arthrobacter globiformis12137ARGLB_039_00430ferredoxin reductase
Brevundimonas diminuta12697BDIM_13970rhodocoxin reductase
Brevundimonas subvibrioides16000Bresu_1559FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Catenulispora acidiphila102108Caci_1305FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Caci_2641FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Caulobacter segnis15250Cseg_0159FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Cseg_3012FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Cellulomonas fimi15513Celf_2109FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Conexibacter woesei100937Cwoe_0443FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Cystobacter fuscus100088D187_005711Ferredoxin reductase
Enterobacter aerogenes13534EAE_03025putative ferredoxin reductase subunit
Escherichia coli3972EcolC_1135FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Escherichia coli13500WFL_13555phenylpropionate dioxygenase ferredoxin reductase subunit
Escherichia coli12713Y75_2535phenylpropionate dioxygenase, ferredoxin reductase subunit
Frateuria aurantia3245Fraau_2257NAD(P)H-nitrite reductase
Gordonia aichiensis108223GOACH_03_02440putative ferredoxin reductase
GOACH_12_00050p-cumate dioxygenase ferredoxin reductase subunit
GOACH_19_00860putative ferredoxin reductase
Gordonia alkanivorans16433GOALK_035_00110putative ferredoxin reductase
GOALK_065_00110putative ferredoxin reductase
Gordonia amicalis100051GOAMI_32_00660putative ferredoxin reductase
Gordonia araii100433GOARA_036_00210ferredoxin reductase
Gordonia hirsuta16056GOHSU_42_00060putative ferredoxin reductase
Gordonia namibiensis108229GONAM_07_00850putative ferredoxin reductase
Gordonia otitidis100426GOOTI_005_00280putative ferredoxin reductase
GOOTI_129_00080putative ferredoxin reductase
Gordonia polyisoprenivorans16320GOPIP_031_00270rhodocoxin reductase
GOPIP_035_00020putative ferredoxin reductase
GOPIP_084_00770putative ferredoxin reductase
GOPIP_094_00970p-cumate dioxygenase ferredoxin reductase subunit
Gordonia rhizosphera16068GORHZ_136_00130putative ferredoxin reductase
GORHZ_145_00240rhodocoxin reductase
GORHZ_200_00170putative ferredoxin reductase
GORHZ_241_00120putative ferredoxin reductase
Gordonia rubripertincta101908GORBP_012_01750putative ferredoxin reductase
GORBP_030_00020putative ferredoxin reductase
GORBP_049_00840putative ferredoxin reductase
Gordonia sputi100414GOSPT_025_00720putative ferredoxin reductase
GOSPT_096_00080putative ferredoxin reductase
Hyphomonas neptunium14232HNE_1888pyridine nucleotide-disulfide oxidoreductase
Intrasporangium calvum12989Intca_1108FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Kitasatospora setae14216KSE_18230putative ferredoxin reductase
KSE_21470putative ferredoxin reductase
Kribbella flavida14399Kfla_4098FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Labrenzia aggregata16684SIAM614_24712FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Marinomonas mediterranea103028Marme_4085Ferredoxin--NAD(+) reductase
Methylobacterium radiotolerans15690Mrad2831_3561FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Nakamurella multipartita105858Namu_0741FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Phaeobacter gallaeciensis16654PGA1_c29270rhodocoxin reductase ThcD
Phycisphaera mikurensis102666PSMK_20850ferredoxin reductase
Rhizobium etli15573RHE_CH01347probable ferredoxin reductase protein
RHE_PE00444ferredoxin reductase protein
Rhizobium sp.101917NGR_b07640pyridine nucleotide-disulphide oxidoreductase family protein
NGR_b14750FAD-dependent pyridine nucleotide-disulphide oxidoreductase
NGR_b16350FAD-dependent pyridine nucleotide-disulphide oxidoreductase
NGR_b17090putative ferredoxin reductase MocF
Rhizobium tropici15247RTCIAT899_CH05730rhodocoxin reductase
RTCIAT899_PC070653-phenylpropionate dioxygenase ferredoxin--NAD(+) reductase component
Rhodobacter capsulatus16581RCAP_rcc03412rhodocoxin reductase
Rhodobacter sphaeroides12203RSP_0900FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Rhodococcus erythropolis100887RER_07950ferredoxin reductase
RER_pREL1-02610ferredoxin reductase
RER_pREL1-02840ferredoxin reductase
Rhodococcus opacus108011ROP_33130ferredoxin reductase
ROP_42790ferredoxin reductase
ROP_45680ferredoxin reductase
ROP_53800rhodocoxin reductase
ROP_54110ferredoxin reductase
ROP_70800ferredoxin reductase
ROP_pROB01-04380rubredoxin reductase
ROP_pROB02-01180ferredoxin reductase
ROP_pROB02-01610benzene dioxygenase ferredoxin reductase subunit
Roseobacter denitrificans15277RD1_0947pyridine nucleotide-disulphide oxidoreductase, putative
Roseobacter litoralis15278RLO149_c001600putative FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Rubrobacter xylanophilus100952Rxyl_2822FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Saccharomonospora azurea14651SacazDRAFT_00945NAD(P)H-nitrite reductase
SacazDRAFT_04396NAD(P)H-nitrite reductase
Saccharomonospora cyanea14841SaccyDRAFT_1723NAD(P)H-nitrite reductase
SaccyDRAFT_3042NAD(P)H-nitrite reductase
Saccharomonospora glauca14831SacglDRAFT_02565NAD(P)H-nitrite reductase
Saccharomonospora viridis12207Svir_17830NAD(FAD)-dependent dehydrogenase
Saccharopolyspora erythraea13426SACE_2839ferredoxin reductase
Saccharopolyspora spinosa15153SspiN1_010100003418pyridine nucleotide-disulfide oxidoreductase
SspiN1_010100003953pyridine nucleotide-disulfide oxidoreductase
SspiN1_010100024537FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Saccharothrix espanaensis15066BN6_38360NAD(P)H-nitrite reductase
Shimwellia blattae105725EB105725_20_005603-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD(+) reductase subunit
Sphingobium japonicum101211SJA_C1-25250anthranilate dioxygenase ferredoxin reductase
Sphingomonas echinoides15742SechA1_010100000615FAD-dependent pyridine nucleotide-disulfide oxidoreductase
SechA1_010100014470FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Sphingomonas wittichii105917Swit_0898FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Swit_2055FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Swit_4920FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Sporichthya polymorpha12702Spopo_31_21400Probable FAD-dependent oxidoreductase
Stackebrandtia nassauensis102104Snas_2738FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Starkeya novella14993Snov_0477FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Streptomyces avermitilis14893SAV6097putative ferredoxin reductase
SAV6956ferredoxin reductase
Streptomyces cattleya14057SCAT_1228putative ferredoxin reductase
SCAT_1535Ferredoxin reductase
Streptomyces clavuligerus13307SCLAV_1321Ferredoxin reductase
SCLAV_5375ferredoxin reductase
Streptomyces ghanaensis15414SSFG_04890ferredoxin reductase
SSFG_05253oxidoreductase
SSFG_06740ferredoxin reductase
Streptomyces mobaraensis13819H340_16886oxidoreductase
Streptomyces pristinaespiralis13074SSDG_01062ferredoxin reductase
Streptomyces purpureus13925STRPU_04_02580FAD-dependent pyridine nucleotide-disulfide oxid oreductase
STRPU_05_03050Ferredoxin reductase
Streptomyces sviceus13980SSEG_05609ferredoxin-NAD(+) reductase
Streptomyces venezuelae13096SVEN_1765Ferredoxin reductase
Streptosporangium roseum3776Sros_2784FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Sros_4928FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Thermobispora bispora14880Tbis_1341FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Thermomicrobium roseumtrd_A0836putidaredoxin reductase
Thermomonospora curvata15933Tcur_3032FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Tsukamurella paurometabola16120Tpau_2747FAD-dependent pyridine nucleotide-disulfide oxidoreductase