遺伝子 : 2-hydroxymuconic semialdehyde dehydrogenase (2HMSD)

遺伝子情報

ID	NRULE_0060
遺伝子ID	2HMSD
作成日	2012/10/04
タンパク質名	Protein name Full 2-hydroxymuconic semialdehyde dehydrogenase Short HMSD EC EC 1.2.1.-
遺伝子名	該当データなし
遺伝子条件	TIGRFAMs; TIGR03216; hit=1
参照	Gene Ontology GO GO:0016620, F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, IEA:InterPro GO:0019439, P:aromatic compound catabolic process, IEA:UniProtKB-KW Enzyme and pathway databases UniPathway UPA00156, - Family and domain databases InterPro IPR016160, Ald_DH_CS IPR015590, Aldehyde_DH_dom IPR017628, OHmuconic_semiald_DH Pfam PF00171, Aldedh, 1 TIGRFAMs TIGR03216, OH_muco_semi_DH, 1 PROSITE PS00070, ALDEHYDE_DEHYDR_CYS, 1 PS00687, ALDEHYDE_DEHYDR_GLU, 1
配列の特徴	P23105 Pseudomonas putida (Arthrobacter siderocapsulatus). ACT_SITE 254 By similarity. ACT_SITE 288 By similarity.
注釈	Function 2-hydroxymuconic acid semialdehyde can be converted to 2-hydroxypent-2,4-dienoate either directly by the action of 2- hydroxymuconic semialdehyde hydrolase (HMSH) or by the action of three sequential enzymes, the first of which is HMSD Sequence similarities Belongs to the aldehyde dehydrogenase family
参考文献	P23105 Pseudomonas putida (Arthrobacter siderocapsulatus). 1791759 DNA sequence determination of the TOL plasmid (pWWO) xylGFJ genes of Pseudomonas putida: implications for the evolution of aromatic catabolism. (Mol Microbiol. 1991) P19059 Pseudomonas sp. (strain CF600). 2194577 Nucleotide sequences of the meta-cleavage pathway enzymes 2-hydroxymuconic semialdehyde dehydrogenase and 2-hydroxymuconic semialdehyde hydrolase from Pseudomonas CF600. (Biochim Biophys Acta. 1990)

関与する機能

機能名
Dihydroxy aromatic compounds degradation (via meta-cleavage pathway)

該当CDS

学名	NBRC番号	CDS	タンパク質名
Actinomadura atramentaria	14695	G339_04045	hypothetical protein
Amycolatopsis azurea	14573	C791_0828	2-aminomuconate semialdehyde dehydrogenase
Chloracidobacterium thermophilum B		Cabther_A0029	2-hydroxymuconate semialdehyde dehydrogenase
Cupriavidus metallidurans	102507	Rmet_1322	2-hydroxymuconic semialdehyde dehydrogenase (HMSD)(protein belongs to CMGI-2)
		Rmet_5206	2-aminomuconic 6-semialdehyde dehydrogenase
Gordonia aichiensis	108223	GOACH_41_00040	putative 2-aminomuconic semialdehyde dehydrogenase
Gordonia sihwensis	108236	GSI01S_07_00410	putative 2-aminomuconic semialdehyde dehydrogenase
Kribbella flavida	14399	Kfla_5493	2-hydroxymuconic semialdehyde dehydrogenase
Micromonospora aurantiaca	16155	Micau_4941	2-hydroxymuconic semialdehyde dehydrogenase
Rhodococcus erythropolis	100887	RER_04700	putative 2-aminomuconic semialdehyde dehydrogenase
		RER_59330	putative 2-aminomuconic semialdehyde dehydrogenase
Salinispora arenicola	105043	Q5S_2535_00040	2-hydroxymuconic semialdehyde dehydrogenase
Salinispora tropica	105044	Strop_3528	aldehyde dehydrogenase
Sphingobium japonicum	101211	SJA_C1-11860	5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
Sphingomonas wittichii	105917	Swit_3519	aldehyde dehydrogenase
Streptosporangium roseum	3776	Sros_9116	Betaine-aldehyde dehydrogenase
Thauera linaloolentis	102519	C666_03870	2-hydroxymuconic semialdehyde dehydrogenase
		C666_16270	2-hydroxymuconic semialdehyde dehydrogenase