遺伝子 : Haloacetate dehalogenase (DEH)

遺伝子情報

ID	NRULE_0075
遺伝子ID	DEH
作成日	2012/10/23
タンパク質名	Protein name Full Haloacetate dehalogenase EC EC 3.8.1.3
遺伝子名	該当データなし
遺伝子条件	BLASTP; Q6NAM1; hit=1; score=680; pid=45
参照	Gene Ontology GO GO:0018785, F:haloacetate dehalogenase activity, IEA:EC GO:0008152, P:metabolic process, IEA:GOC Phylogenomic databases eggNOG COG0596, - HOGENOM HOG000028073, - KO K01561, - ProtClustDB CLSK911742, - Family and domain databases InterPro IPR000073, AB_hydrolase_1 IPR000639, Epox_hydrolase-like PRINTS PR00111, ABHYDROLASE PR00412, EPOXHYDRLASE
配列の特徴	Q6NAM1 Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009). ACT_SITE 110 Nucleophile. ACT_SITE 280 Proton acceptor. BINDING 111 Substrate. BINDING 114 Substrate. BINDING 155 Substrate. BINDING 156 Substrate. BINDING 219 Substrate.
注釈	Function Catalyzes the hydrolytic dehalogenation of haloacetate to produce glycolate Catalytic activity Haloacetate + H(2)O = glycolate + halide Subunit structure Homodimer Sequence similarities Belongs to the AB hydrolase superfamily. Epoxide hydrolase family
参考文献	Q6NAM1 Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009). 21255311 Sequence- and activity-based screening of microbial genomes for novel dehalogenases. (Microb Biotechnol. 2010) 21510690 Mapping the reaction coordinates of enzymatic defluorination. (J Am Chem Soc. 2011) Q01398 Moraxella sp. (strain B). 1512562 Lack of homology between two haloacetate dehalogenase genes encoded on a plasmid from Moraxella sp. strain B. (J Gen Microbiol. 1992)

関与する機能

機能名
Haloalkane degradation (conversion into hydroxyacid)

該当CDS

学名	NBRC番号	CDS	タンパク質名
Acidiphilium multivorum	100883	ACMV_06090	hypothetical protein
Azorhizobium caulinodans	14845	AZC_2387	alpha/beta hydrolase
Bradyrhizobium diazoefficiens	14792	bll7497	putative haloacetate dehalogenase (EC 3.8.1.3)
Labrenzia aggregata	16684	SIAM614_06063	Alpha/beta hydrolase
Nocardiopsis dassonvillei	14626	Ndas_0829	alpha/beta hydrolase fold protein
Nostoc sp.		alr0039	putative hydrolase
Saccharopolyspora erythraea	13426	SACE_2847	probable epoxide alpha/beta hydrolase
Sporichthya polymorpha	12702	Spopo_30_07590	Putative hydrolase or acyltransferase of alpha/b eta superfamily