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Rule : NADPH azoreductase (AZR)

Rule Description

ID NRULE_0237
Rule name AZR
Created 2013-08-26
Protein name
Protein name
Full
NADPH azoreductase
EC
EC 1.7.1.6
Gene name Not assigned
Rule Trigger BLASTP; Q9FAW5; hit=1; score=400; pid=45
OR
BLASTP; Q50H63; hit=1; score=490; pid=70
Cross Reference
Family and domain databases
InterPro
IPR005025, FMN_red
Pfam
PF03358, FMN_red, 1
Feature
Q9FAW5 Bacillus sp. (strain OY1-2).
NP_BIND106 - 111NADP (Potential).
General annotation
Function
Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADPH, but not NADH, as an electron donor for its activity. The enzyme can also reduce a wide range of sulfonated azo dyes
Sequence similarities
Belongs to the azoreductase type 2 family
Reference
Q9FAW5 Bacillus sp. (strain OY1-2).
11134015
Molecular cloning and characterization of the gene coding for azoreductase from Bacillus sp. OY1-2 isolated from soil. (J Biol Chem. 2001)
Q50H63 Staphylococcus aureus.
15870453
Biochemical and molecular characterization of an azoreductase from Staphylococcus aureus, a tetrameric NADPH-dependent flavoprotein. (Microbiology. 2005)



Related Function

Function name
Aromatic azo compounds degradation

CDS

Data Download
Scientific name NBRC No. CDS Product name
Bacillus amyloliquefaciens15535BAMF_1030oxidoreductase, NAD(P)H-FMN and ferric iron reductase
Bacillus atrophaeus13721BATRMS_10_08510NADPH-dependent FMN reductase YhdA
Bacillus cereus15305BC_2229Azoreductase
Bacillus licheniformis12200BL02896putative NADPH-dependent FMN reductase YhdA
Bacillus licheniformis12195BLi01002putative NADPH-dependent FMN reductase YhdA
Bacillus mojavensis15718GYU_13_01830NADPH-dependent FMN reductase YhdA
Bacillus mycoides101228bmyco0001_19940NADPH azoreductase
Bacillus pseudomycoides101232bpmyx0001_20140NADPH azoreductase
Bacillus subtilis3134BSU6633_14662oxidoreductase, NAD(P)H-FMN and ferric iron reductase
Bacillus subtilis subsp. subtilis13719BSU09340oxidoreductase, NAD(P)H-FMN and ferric iron reductase
Bacillus thuringiensis101235bthur0008_20920NADPH azoreductase
Bacillus vallismortis101236BvalD_010100008273oxidoreductase, NAD(P)H-FMN and ferric iron reductase
Staphylococcus epidermidis12993SE_0330conserved hypothetical protein
Staphylococcus saprophyticus subsp. saprophyticus102446SSP2154conserved hypothetical protein