English site

遺伝子 : DtxR family transcriptional regulator MntR (MNTR)

遺伝子情報

ID NRULE_0327
遺伝子ID MNTR
作成日 2014/10/09
タンパク質名
Protein name
Full
DtxR family transcriptional regulator MntR
Synonym
Full
Manganese transport regulator MntR
遺伝子名 mntR
遺伝子条件 HAMAP; MF_00732; hit=1
参照
Gene Ontology
GO
GO:0005737, C:cytoplasm, IEA:UniProtKB-HAMAP
GO:0003677, F:DNA binding, IEA:UniProtKB-HAMAP
GO:0030145, F:manganese ion binding, IEA:UniProtKB-HAMAP
GO:0003700, F:sequence-specific DNA binding transcription factor activity, IEA:UniProtKB-HAMAP
GO:0030026, P:cellular manganese ion homeostasis, IEA:UniProtKB-HAMAP
GO:0045893, P:positive regulation of transcription, DNA-templated, IEA:UniProtKB-HAMAP
GO:0006351, P:transcription, DNA-templated, IEA:UniProtKB-KW
Phylogenomic databases
eggNOG
COG1321, -
HOGENOM
HOG000040349, -
Family and domain databases
HAMAP
MF_00732, HTH_MntR, 1
InterPro
IPR001367, Fe_dep_repressor
IPR022689, Fe_dep_repressor_HTH_DtxR
IPR022687, Fe_dep_repressor_HTH_DtxR_N
IPR022897, Tscrpt_reg_MntR
IPR011991, WHTH_DNA-bd_dom
Pfam
PF02742, Fe_dep_repr_C, 1
PF01325, Fe_dep_repress, 1
SMART
SM00529, HTH_DTXR, 1
PROSITE
PS50944, HTH_DTXR, 1
配列の特徴 該当データなし
注釈
Function
Central regulator of manganese homeostasis. In the presence of manganese, it mediates repression of the manganese transporter MntH; under low manganese conditions, it activates the transcription of the mntABCD operon
Domain
Contains 1 HTH dtxR-type DNA-binding domain and a metal-binding domain
参考文献
P54512 Bacillus subtilis (strain 168).
10760146
Manganese homeostasis in Bacillus subtilis is regulated by MntR, a bifunctional regulator related to the diphtheria toxin repressor family of proteins. (Mol Microbiol. 2000)
23298157
Roles of the A and C sites in the manganese-specific activation of MntR. (Biochemistry. 2013)



関与する機能

機能名
Metal-binding protein

該当CDS

データダウンロード
学名 NBRC番号 CDS タンパク質名
Anoxybacillus flavithermus15317Aflv_0923Mn-dependent transcriptional regulator (DtxR family)
Bacillus amyloliquefaciens15535BAMF_2355transcriptional regulator (DtxR family)
Bacillus atrophaeus13721BATRMS_17_04870manganese transport transcriptional regulator
Bacillus cereus15305BC_4204Manganese transport transcription regulator
Bacillus licheniformis12200BL01547transcriptional regulator
Bacillus licheniformis12195BLi02623HTH-type transcription regulator MntR
Bacillus mojavensis15718GYU_43_00340manganese transport transcriptional regulator
Bacillus mycoides101228bmyco0001_38340Transcriptional regulator mntR
Bacillus pseudomycoides101232bpmyx0001_36880Transcriptional regulator mntR
Bacillus psychrosaccharolyticus101233WYK_196_00240manganese transport transcriptional regulator
Bacillus pumilus12092BAT_1830manganese
Bacillus subtilis3134BSU6633_19947manganese transport transcriptional regulator
Bacillus subtilis subsp. subtilis13719BSU24520transcriptional regulator (DtxR family)
Bacillus thuringiensis101235bthur0008_40030Transcriptional regulator mntR
Bacillus vallismortis101236BvalD_010100003197manganese transport transcriptional regulator
Brevibacillus brevis100599BBR47_23060transcriptional regulator MntR
Halobacillus halophilus102448HBHAL_3497iron-dependent repressor family protein
Paenibacillus alvei3343PAV_3c04500transcriptional regulator MntR
Paenibacillus peoriae15541PpeoK3_010100004850transcriptional regulator mntR Manganese transport regulator
Paenibacillus polymyxa15309PPT_17145peptidase U32