| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
Q70HZ6_9ACTO (Q70HZ6) |
|
|
0.0 |
870 |
100% |
|
- Product
- Putative cytochrome P450
- Gene
- borI
- Organism
- Streptomyces parvulus
|
1uniprot[Pubmed] 15112998 Biosynthesis of the angiogenesis inhibitor borrelidin by Streptomyces parvulus Tu4055: cluster analysis and assignment of functions.(Chem. Biol.) [2004] | 2uniprot Evidence from engineered gene fusions for the repeated use of a module in a modular polyketide synthase";.(Chem. Commun. (Camb.)) [2003] |
|
2
|
Q9ZHQ1_STRFR (Q9ZHQ1) |
|
|
6e-79 |
299 |
43% |
|
- Product
- Cytochrome P450
- Gene
- tylH1
- Organism
- Streptomyces fradiae
Streptomyces roseoflavus
|
1uniprot[Pubmed] 10220165 [Medline] 99235571 The tylosin biosynthetic cluster from Streptomyces fradiae: genetic organization of the left region.(Microbiology) [1999] |
|
5
|
Q331Q9_9ACTO (Q331Q9) |
|
|
2e-77 |
294 |
40% |
|
- Product
- Cytochrome P-450
- Gene
- gerPIII
- Organism
- Streptomyces sp. KCTC 0041BP
|
1uniprot[Pubmed] 17053005 Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007] | 2uniprot Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006] |
|
6
|
CPXE_STRGO (P18326) |
|
|
2e-74 |
284 |
39% |
|
- Product
- Cytochrome P450-SU1
CYP105A1 Cytochrome P450-CVA1
- Gene
- CYP105A1
suaC
- Organism
- Streptomyces griseolus
|
1uniprot[Pubmed] 2345149 [Medline] 90264332 Genes for two herbicide-inducible cytochromes P-450 from Streptomyces griseolus.(J. Bacteriol.) [1990] |
|
8
|
Q5SFA8_STRBI (Q5SFA8) |
|
|
3e-74 |
283 |
38% |
|
- Product
- P450
- Gene
- chmHI
- Organism
- Streptomyces bikiniensis
|
1uniprot[Pubmed] 15561847 Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.(Antimicrob. Agents Chemother.) [2004] |
|
11
|
CPS2_STRCC (Q59831) |
|
|
1e-72 |
278 |
38% |
|
- Product
- Cytochrome P450 105A3
Cytochrome P450 sca-2 Cytochrome P450 sca-2
- Gene
- CYP105A3
- Organism
- Streptomyces carbophilus
|
1uniprot[Pubmed] 7557483 [Medline] 96001248 Cloning, characterization and expression of the gene encoding cytochrome P-450sca-2 from Streptomyces carbophilus involved in production of pravastatin, a specific HMG-CoA reductase inhibitor.(Gene) [1995] | 2uniprot[Pubmed] 2509201 [Medline] 90032660 Purification and characterization of cytochrome P-450sca from Streptomyces carbophilus. ML-236B (compactin) induces a cytochrome P-450sca in Streptomyces carbophilus that hydroxylates ML-236B to pravastatin sodium (CS-514), a tissue-selective inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme-A reductase.(Eur. J. Biochem.) [1989] | 3uniprot[Pubmed] 10329788 [Medline] 99263338 Crystallization and preliminary X-ray diffraction analysis of cytochrome P450sca-2 from Streptomyces carbophilus involved in production of pravastatin sodium, a tissue-selective inhibitor of HMG-CoA reductase.(Acta Crystallogr. D) [1999] | [pubmed all]
|
12
|
Q2L6S8_9ACTO (Q2L6S8) |
|
|
1e-72 |
278 |
38% |
|
- Product
- Cytochrome P450 type compactin 3'',4''-hydroxylase
- Gene
- moxA
- Organism
- Nonomuraea recticatena
|
1uniprot[Pubmed] 16428858 Hydroxylation of testosterone by bacterial cytochromes P450 using the Escherichia coli expression system.(Biosci. Biotechnol. Biochem.) [2006] | 2uniprot[Pubmed] 17679139 Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105).(Biochem. Biophys. Res. Commun.) [2007] | [pubmed all]
|
14
|
D0U2E9_STRPT (D0U2E9) |
|
|
4e-72 |
276 |
39% |
|
- Product
- Hydroxylase
- Gene
-
- Organism
- Streptomyces platensis subsp. rosaceus
|
1uniprot[Pubmed] 19726666 iso-Migrastatin, migrastatin, and dorrigocin production in Streptomyces platensis NRRL 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase.(J. Biol. Chem.) [2009] |
|
17
|
O85697_STRLI (O85697) |
|
|
2e-70 |
271 |
38% |
|
- Product
- Putative cytochrome P450 oxidoreductase
- Gene
-
- Organism
- Streptomyces lividans
|
1uniprot[Pubmed] 10627032 [Medline] 20090458 AUD4, a new amplifiable element from Streptomyces lividans.(Microbiology) [1999] |
|
19
|
Q9EWS4_STRCO (Q9EWS4) |
|
|
3e-70 |
270 |
38% |
|
- Product
- Putative cytochrome P450
- Gene
- SCO0774
- Organism
- Streptomyces coelicolor
|
1uniprot[Pubmed] 12000953 [Medline] 21996410 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002] |
|
21
|
Q595S4_9ACTO (Q595S4) |
|
|
1e-69 |
268 |
37% |
|
- Product
- Cytochrome P450 monooxygenase CYP105D8
- Gene
- cyp233
- Organism
- Streptomyces tubercidicus
|
1uniprot[Pubmed] 16269732 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005] | 2uniprot[Pubmed] 16269733 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005] | [pubmed all]
|
22
|
Q825I8_STRAW (Q825I8) |
|
|
4e-69 |
266 |
38% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- cyp28
SAV7469 SAV_7469
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
23
|
D3PYH2_STANL (D3PYH2) |
|
|
5e-69 |
266 |
38% |
|
- Product
- Cytochrome P450
- Gene
- Snas_1843
- Organism
- Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
|
1uniprot Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009] |
|
28
|
A4FF79_SACEN (A4FF79) |
|
|
2e-67 |
261 |
39% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- cyp28
SACE_3429
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
29
|
A8KXU3_FRASN (A8KXU3) |
|
|
2e-67 |
261 |
36% |
|
- Product
- Cytochrome P450
- Gene
- Franean1_3475
- Organism
- Frankia sp. (strain EAN1pec)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
31
|
Q83WF5_MICGR (Q83WF5) |
|
|
5e-67 |
259 |
36% |
|
- Product
- Cytochrome P450
- Gene
- mycCI
- Organism
- Micromonospora griseorubida
|
1uniprot[Pubmed] 12583909 [Medline] 22472038 Organization of the biosynthetic gene cluster for the polyketide macrolide mycinamicin in Micromonospora griseorubida.(FEMS Microbiol. Lett.) [2003] |
|
34
|
Q2L6S5_9ACTO (Q2L6S5) |
|
|
1e-66 |
258 |
38% |
|
- Product
- Cytochrome P450 type compactin 6beta-hydroxylase
- Gene
- boxA
- Organism
- Streptomyces sp. TM-7
|
1uniprot[Pubmed] 16428858 Hydroxylation of testosterone by bacterial cytochromes P450 using the Escherichia coli expression system.(Biosci. Biotechnol. Biochem.) [2006] |
|
37
|
F4F7G4_VERMA (F4F7G4) |
|
|
3e-66 |
257 |
36% |
|
- Product
- Cytochrome P450
- Gene
- VAB18032_16485
- Organism
- Verrucosispora maris (strain AB-18-032)
|
1uniprot[Pubmed] 21551311 Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011] |
|
38
|
Q5ENH9_PSEAH (Q5ENH9) |
|
|
4e-66 |
256 |
36% |
|
- Product
- FadC
- Gene
- fadC
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 15752735 A gene cluster for the fatty acid catabolism from Pseudonocardia autotrophica BCRC12444.(Biochem. Biophys. Res. Commun.) [2005] |
|
39
|
D8I293_AMYMU (D8I293) |
|
|
4e-66 |
256 |
38% |
|
- Product
- Cytochrome P450
- Gene
- AMED_0875
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
41
|
D8I6K7_AMYMU (D8I6K7) |
|
|
4e-65 |
253 |
37% |
|
- Product
- Cytochrome P450
- Gene
- AMED_7211
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
42
|
D2AYJ7_STRRD (D2AYJ7) |
|
|
4e-65 |
253 |
35% |
|
- Product
- Putative cytochrome P450
- Gene
- Sros_6255
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
44
|
B3XWK3_9ACTO (B3XWK3) |
|
|
5e-65 |
253 |
37% |
|
- Product
- Cytochrome P450 monooxygenase
- Gene
- psmA
- Organism
- Streptomyces sp. A-1544
|
1uniprot[Pubmed] 18640605 Increase in pladienolide D production rate using a Streptomyces strain overexpressing a cytochrome P450 gene.(J. Biosci. Bioeng.) [2008] |
|
46
|
D3Q1N8_STANL (D3Q1N8) |
|
|
9e-65 |
252 |
36% |
|
- Product
- Cytochrome P450
- Gene
- Snas_0166
- Organism
- Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
|
1uniprot Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009] |
|
49
|
Q8KRU0_PSEAH (Q8KRU0) |
|
|
3e-64 |
250 |
35% |
|
- Product
- PauC
- Gene
- pauC
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot Molecular cloning and analysis of the gene for P-450 hydroxylase from Pseudonocardia autotrophica IFO12743.(J. Microbiol.) [2002] |
|
51
|
D2B913_STRRD (D2B913) |
|
|
5e-64 |
249 |
37% |
|
- Product
- Putative cytochrome P450
- Gene
- Sros_7070
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
54
|
D8I294_AMYMU (D8I294) |
|
|
1e-63 |
248 |
37% |
|
- Product
- Cytochrome P450
- Gene
- AMED_0876
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
55
|
F2RDD2_STRVP (F2RDD2) |
|
|
3e-63 |
247 |
36% |
|
- Product
- Putative cytochrome P450 hydroxylase
- Gene
- SVEN_6138
- Organism
- Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
|
1uniprot[Pubmed] 21463507 Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011] |
|
56
|
Q79ZT5_STRAW (Q79ZT5) |
|
|
3e-63 |
247 |
35% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- pteD
SAV412 SAV_412
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
58
|
Q93H80_STRAW (Q93H80) |
|
|
3e-63 |
247 |
35% |
|
- Product
- Cytochrome P450
- Gene
- pteD
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 20375018 Regio- and stereospecificity of filipin hydroxylation sites revealed by crystal structures of cytochrome P450 105P1 and 105D6 from Streptomyces avermitilis.(J. Biol. Chem.) [2010] | [pubmed all]
|
59
|
E4NBF9_KITSK (E4NBF9) |
|
|
3e-63 |
247 |
37% |
|
- Product
- Putative cytochrome P450
- Gene
- KSE_27280
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
60
|
D8HXB0_AMYMU (D8HXB0) |
|
|
4e-63 |
246 |
36% |
|
- Product
- Cytochrome P450
- Gene
- AMED_6381
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
61
|
D8I8M5_AMYMU (D8I8M5) |
|
|
4e-63 |
246 |
38% |
|
- Product
- Cytochrome P450
- Gene
- AMED_3577
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
62
|
C7MXK5_SACVD (C7MXK5) |
|
|
5e-63 |
246 |
37% |
|
- Product
- Cytochrome P450
- Gene
- Svir_22760
- Organism
- Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
|
1uniprot Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009] |
|
65
|
Q595S0_9ACTO (Q595S0) |
|
|
1e-62 |
244 |
34% |
|
- Product
- Cytochrome P450 monooxygenase CYP105S2
- Gene
- cyp234
- Organism
- Streptomyces tubercidicus
|
1uniprot[Pubmed] 16269732 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005] | 2uniprot[Pubmed] 16269733 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005] | [pubmed all]
|
71
|
D2B704_STRRD (D2B704) |
|
|
3e-62 |
244 |
35% |
|
- Product
- Putative cytochrome P450
- Gene
- Sros_4934
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
72
|
Q595R1_9ACTO (Q595R1) |
|
|
4e-62 |
243 |
34% |
|
- Product
- Cytochrome P450 monooxygenase CYP105S1
- Gene
- cyp230
- Organism
- Streptomyces tubercidicus
|
1uniprot[Pubmed] 16269732 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005] | 2uniprot[Pubmed] 16269733 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005] | [pubmed all]
|
73
|
C6WQG7_ACTMD (C6WQG7) |
|
|
4e-62 |
243 |
36% |
|
- Product
- Cytochrome P450
- Gene
- Amir_2894
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
74
|
D7B189_NOCDD (D7B189) |
|
|
5e-62 |
243 |
36% |
|
- Product
- Cytochrome P450
- Gene
- Ndas_1037
- Organism
- Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
|
1uniprot Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010] |
|
75
|
C6W8T3_ACTMD (C6W8T3) |
|
|
6e-62 |
243 |
36% |
|
- Product
- Cytochrome P450
- Gene
- Amir_3276
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
78
|
F3NES9_9ACTO (F3NES9) |
|
|
1e-61 |
242 |
36% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- SGM_1643
- Organism
- Streptomyces griseoaurantiacus M045
|
1uniprot[Pubmed] 21551298 Draft Genome Sequence of the Marine Bacterium Streptomyces griseoaurantiacus M045, Which Produces Novel Manumycin-Type Antibiotics with a pABA Core Component.(J. Bacteriol.) [2011] |
|
82
|
Q156A0_AMYOR (Q156A0) |
|
|
3e-61 |
241 |
35% |
|
- Product
- Epothilone b hydroxylase
- Gene
- ebh
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 16972046 Cloning and expression of a cytochrome P450 hydroxylase gene from Amycolatopsis orientalis: hydroxylation of epothilone B for the production of epothilone F.(J. Ind. Microbiol. Biotechnol.) [2007] |
|
83
|
Q8KSY0_9ACTO (Q8KSY0) |
|
|
3e-61 |
241 |
35% |
|
- Product
- Putative cytochrome P450 GrhO3
- Gene
- grhO3
- Organism
- Streptomyces sp. JP95
|
1uniprot[Pubmed] 12323376 [Medline] 22235582 A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A.(Chem. Biol.) [2002] |
|
94
|
Q70AS0_STRPE (Q70AS0) |
|
|
1e-60 |
239 |
35% |
|
- Product
- Putative cytochrome P450
- Gene
- cyp8812
- Organism
- Streptomyces peucetius
|
1uniprot[Pubmed] 15111132 Genome analyses of Streptomyces peucetius ATCC 27952 for the identification and comparison of cytochrome P450 complement with other Streptomyces.(Arch. Biochem. Biophys.) [2004] |
|
97
|
D3Q5W0_STANL (D3Q5W0) |
|
|
1e-60 |
238 |
34% |
|
- Product
- Cytochrome P450
- Gene
- Snas_0545
- Organism
- Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
|
1uniprot Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009] |
|
98
|
C4B4V3_9ACTO (C4B4V3) |
|
|
1e-60 |
238 |
34% |
|
- Product
- P450
- Gene
- dvbA
- Organism
- Dactylosporangium variesporum
|
1uniprot Efficient Biotransformations Using Escherichia coli with tolC acrAB Mutations Expressing Cytochrome P450 Genes.(Biosci. Biotechnol. Biochem.) [2009] |
|
99
|
Q8KNC8_MICEC (Q8KNC8) |
|
|
2e-60 |
238 |
36% |
|
- Product
- CalE10
- Gene
- calE10
- Organism
- Micromonospora echinospora
Micromonospora purpurea
|
1uniprot[Pubmed] 12183629 [Medline] 22171414 The calicheamicin gene cluster and its iterative type I enediyne PKS.(Science) [2002] |
|