| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
Q9L4V9_9ACTO (Q9L4V9) |
|
|
0.0 |
1779 |
100% |
|
- Product
- NysRIII
- Gene
- nysRIII
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
4
|
Q6W5R2_9ACTO (Q6W5R2) |
|
|
0.0 |
737 |
51% |
|
- Product
- FscRII
- Gene
- fscRII
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
5
|
D7C1U8_STRBB (D7C1U8) |
|
|
0.0 |
713 |
52% |
|
- Product
- Transcriptional regulator, LuxR family protein
- Gene
- SBI_09031
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
6
|
Q5QES5_9ACTO (Q5QES5) |
|
|
1e-170 |
603 |
47% |
|
- Product
- AmphRIII
- Gene
-
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 15563836 Analysis and manipulation of amphotericin biosynthetic genes by means of modified phage KC515 transduction techniques.(Gene) [2004] |
|
7
|
Q9EWC6_STRGR (Q9EWC6) |
|
|
1e-129 |
468 |
51% |
|
- Product
- Cho-like protein
- Gene
-
- Organism
- Streptomyces griseus
|
1uniprot[Pubmed] 11782498 [Medline] 21642576 The candicidin gene cluster from Streptomyces griseus IMRU 3570.(Microbiology) [2002] |
|
8
|
Q197Z0_9ACTO (Q197Z0) |
|
|
1e-110 |
406 |
37% |
|
- Product
- SalRII
- Gene
- salRII
- Organism
- Streptomyces albus
|
1uniprot[Pubmed] 18062184 Multiple regulatory genes in the salinomycin biosynthetic gene cluster of Streptomyces albus CCM 4719.(Folia Microbiol. (Praha)) [2007] |
|
9
|
D2CKM8_PSEAH (D2CKM8) |
|
|
3e-97 |
361 |
39% |
|
- Product
- CppRIII
- Gene
- cppRIII
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 19697072 Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009] |
|
11
|
Q55103_STRSQ (Q55103) |
|
|
2e-94 |
352 |
44% |
|
- Product
- Cho-Orf2
- Gene
- cho-orf2
- Organism
- Streptomyces sp
|
1uniprot[Pubmed] 2361941 [Medline] 90299781 An operon containing the genes for cholesterol oxidase and a cytochrome P-450-like protein from a Streptomyces sp.(J. Bacteriol.) [1990] | 2uniprot Nucleotide sequence analysis of a region upstream of the cholesterol oxidase-cytochrome P450 operon of Streptomyces sp. SA-COO revealing repeating units coding for putative transmembrane and DNA-binding proteins.(J. Ferment. Bioeng.) [1993] |
|
12
|
D2CKN2_PSEAH (D2CKN2) |
|
|
2e-91 |
342 |
35% |
|
- Product
- CppRV
- Gene
- cppRV
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 19697072 Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009] |
|
14
|
Q0QMP3_9ACTO (Q0QMP3) |
|
|
5e-86 |
324 |
35% |
|
- Product
- Regulator
- Gene
-
- Organism
- Streptomyces sp. Eco86
|
1uniprot[Pubmed] 16724457 Isolation and identification of three new 5-alkenyl-3,3(2H)-furanones from two streptomyces species using a genomic screening approach.(J. Antibiot.) [2006] |
|
16
|
D7C1U6_STRBB (D7C1U6) |
|
|
1e-50 |
207 |
32% |
|
- Product
- Transcriptional regulator, LuxR family protein
- Gene
- SBI_09029
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
17
|
Q9L4W1_9ACTO (Q9L4W1) |
|
|
2e-46 |
192 |
32% |
|
- Product
- NysRI
- Gene
- nysRI
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
18
|
B1W483_STRGG (B1W483) |
|
(2 hsp) |
4e-46 |
191 |
33% |
|
- Product
- Putative LAL subfamily transcriptional regulator
- Gene
- SGR_6071
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
19
|
Q6F498_STRGR (Q6F498) |
|
(2 hsp) |
4e-46 |
191 |
33% |
|
- Product
- Putative transcriptional regulator, similar to LAL subfamily
- Gene
- orf1-AdBS4
- Organism
- Streptomyces griseus
|
1uniprot[Pubmed] 15228534 DNA-binding specificity of AdpA, a transcriptional activator in the A-factor regulatory cascade in Streptomyces griseus.(Mol. Microbiol.) [2004] |
|
24
|
D2CKM6_PSEAH (D2CKM6) |
|
|
8e-41 |
174 |
32% |
|
- Product
- CppRI
- Gene
- cppRI
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 19697072 Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009] |
|
25
|
D1GLT1_9ACTO (D1GLT1) |
|
|
1e-40 |
174 |
30% |
|
- Product
- LuxR-family transcriptional regulator
- Gene
- slgR2
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
28
|
Q6W5R0_9ACTO (Q6W5R0) |
|
|
5e-39 |
168 |
30% |
|
- Product
- FscRIV
- Gene
- fscRIV
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
29
|
Q55104_STRSQ (Q55104) |
|
|
2e-38 |
166 |
44% |
|
- Product
- Cho-Orf1
- Gene
- cho-orf1
- Organism
- Streptomyces sp
|
1uniprot[Pubmed] 2361941 [Medline] 90299781 An operon containing the genes for cholesterol oxidase and a cytochrome P-450-like protein from a Streptomyces sp.(J. Bacteriol.) [1990] | 2uniprot Nucleotide sequence analysis of a region upstream of the cholesterol oxidase-cytochrome P450 operon of Streptomyces sp. SA-COO revealing repeating units coding for putative transmembrane and DNA-binding proteins.(J. Ferment. Bioeng.) [1993] |
|
31
|
D2ATJ5_STRRD (D2ATJ5) |
|
|
4e-37 |
162 |
28% |
|
- Product
- ATPase-like protein
- Gene
- Sros_3795
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
33
|
E9KTI8_9ACTO (E9KTI8) |
|
|
2e-36 |
159 |
30% |
|
- Product
- Cholesterol oxidase regulator
- Gene
- fkbN
Tcs_11604BP_034
- Organism
- Streptomyces sp. KCTC 11604BP
|
1uniprot[Pubmed] 21175203 Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011] |
|
34
|
F1DI40_9ACTO (F1DI40) |
|
|
5e-36 |
158 |
29% |
|
- Product
- TrdH
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
35
|
D3Y1J2_9ACTO (D3Y1J2) |
|
|
9e-36 |
157 |
29% |
|
- Product
- TamH
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
36
|
Q9ZGI0_9ACTO (Q9ZGI0) |
|
|
1e-35 |
157 |
29% |
|
- Product
- Putative transcriptional activator PikD
- Gene
- pikD
- Organism
- Streptomyces venezuelae
|
1uniprot[Pubmed] 9770448 [Medline] 98445333 A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998] | 2uniprot[Pubmed] 9831532 [Medline] 99051447 Hydroxylation of macrolactones YC-17 and narbomycin is mediated by the pikC-encoded cytochrome P450 in Streptomyces venezuelae.(Chem. Biol.) [1998] | [pubmed all]
|
37
|
Q68CI0_STRCZ (Q68CI0) |
|
|
3e-35 |
155 |
29% |
|
- Product
- Putative activator
- Gene
-
- Organism
- Streptomyces carzinostaticus
|
1uniprot[Pubmed] 15328113 Cloning, sequencing, and functional analysis of an iterative type I polyketide synthase gene cluster for biosynthesis of the antitumor chlorinated polyenone neocarzilin in "Streptomyces carzinostaticus".(Antimicrob. Agents Chemother.) [2004] |
|
41
|
Q5QES7_9ACTO (Q5QES7) |
|
|
3e-33 |
149 |
32% |
|
- Product
- AmphRI
- Gene
-
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 15563836 Analysis and manipulation of amphotericin biosynthetic genes by means of modified phage KC515 transduction techniques.(Gene) [2004] |
|
42
|
D2CKN3_PSEAH (D2CKN3) |
|
|
4e-33 |
149 |
34% |
|
- Product
- CppRVI
- Gene
- cppRVI
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 19697072 Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009] |
|
43
|
Q55102_STRSQ (Q55102) |
|
|
5e-32 |
145 |
30% |
|
- Product
- Cho-Orf3
- Gene
- cho-orf3
- Organism
- Streptomyces sp
|
1uniprot[Pubmed] 2361941 [Medline] 90299781 An operon containing the genes for cholesterol oxidase and a cytochrome P-450-like protein from a Streptomyces sp.(J. Bacteriol.) [1990] | 2uniprot Nucleotide sequence analysis of a region upstream of the cholesterol oxidase-cytochrome P450 operon of Streptomyces sp. SA-COO revealing repeating units coding for putative transmembrane and DNA-binding proteins.(J. Ferment. Bioeng.) [1993] |
|
49
|
Q197Y9_9ACTO (Q197Y9) |
|
(2 hsp) |
1e-29 |
137 |
32% |
|
- Product
- SalRI
- Gene
- salRI
- Organism
- Streptomyces albus
|
1uniprot[Pubmed] 18062184 Multiple regulatory genes in the salinomycin biosynthetic gene cluster of Streptomyces albus CCM 4719.(Folia Microbiol. (Praha)) [2007] |
|
50
|
C7MX51_SACVD (C7MX51) |
|
|
3e-29 |
135 |
29% |
|
- Product
- Transcriptional regulator, luxR family
- Gene
- Svir_29900
- Organism
- Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
|
1uniprot Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009] |
|
51
|
E9KTC1_STRKN (E9KTC1) |
|
|
6e-29 |
134 |
29% |
|
- Product
- Cholesterol oxidase regulator
- Gene
- fkbN
Tcs_SK_037
- Organism
- Streptomyces kanamyceticus
|
1uniprot[Pubmed] 21175203 Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011] |
|
53
|
Q9KID4_STRHY (Q9KID4) |
|
|
6e-28 |
131 |
29% |
|
- Product
- FkbN
- Gene
- fkbN
- Organism
- Streptomyces hygroscopicus subsp. ascomyceticus
|
1uniprot[Pubmed] 10863099 [Medline] 20323220 The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.(Gene) [2000] |
|
57
|
A8LFZ6_FRASN (A8LFZ6) |
|
|
4e-26 |
125 |
31% |
|
- Product
- Transcriptional regulator, LuxR family
- Gene
- Franean1_4833
- Organism
- Frankia sp. (strain EAN1pec)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
59
|
B6CWI5_STRRM (B6CWI5) |
|
(2 hsp) |
4e-26 |
125 |
33% |
|
- Product
- ToyA
- Gene
- toyA
- Organism
- Streptomyces rimosus
|
1uniprot[Pubmed] 18721750 Deciphering deazapurine biosynthesis: pathway for pyrrolopyrimidine nucleosides toyocamycin and sangivamycin.(Chem. Biol.) [2008] |
|
63
|
Q767F4_9ACTO (Q767F4) |
|
|
2e-25 |
122 |
42% |
|
- Product
- Putative transcriptional regulator
- Gene
-
- Organism
- Actinoplanes sp. A40644
|
1uniprot[Pubmed] 14763562 A relationship between the mevalonate pathway and isoprenoid production in actinomycetes.(J. Antibiot.) [2003] |
|
65
|
C3VLY0_9ACTO (C3VLY0) |
|
|
1e-24 |
120 |
26% |
|
- Product
- LuxR-type transcriptional regulator
- Gene
- mlaH
- Organism
- Streptomyces sp. MP39-85
|
1uniprot[Pubmed] 19854930 Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010] |
|
66
|
E9L1I7_9ZZZZ (E9L1I7) |
|
|
2e-24 |
119 |
31% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA37-43
- Organism
- uncultured organism CA37
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
67
|
F2R5P8_STRVP (F2R5P8) |
|
|
5e-24 |
118 |
28% |
|
- Product
- Putative uncharacterized protein SVEN_0272
- Gene
- SVEN_0272
- Organism
- Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
|
1uniprot[Pubmed] 21463507 Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011] |
|
68
|
A1YAL2_AMYOR (A1YAL2) |
|
(2 hsp) |
6e-24 |
118 |
31% |
|
- Product
- Transcriptional regulator
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 17136886 Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006] |
|
73
|
E4N8L9_KITSK (E4N8L9) |
|
|
4e-23 |
115 |
26% |
|
- Product
- Putative regulatory protein
- Gene
- KSE_17260
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
74
|
A4FDL9_SACEN (A4FDL9) |
|
|
5e-23 |
115 |
28% |
|
- Product
- LuxR-family transcriptional regulator
- Gene
- gdmRII
SACE_2866
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
75
|
Q846X0_STRCM (Q846X0) |
|
(2 hsp) |
5e-23 |
115 |
30% |
|
- Product
- Putative regulatory protein
- Gene
- monH
- Organism
- Streptomyces cinnamonensis
|
1uniprot[Pubmed] 12940979 [Medline] 22823264 Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization.(Mol. Microbiol.) [2003] | 2uniprot The gene cluster for monensin biosynthesis. [1999] |
|
76
|
D8I5D8_AMYMU (D8I5D8) |
|
(2 hsp) |
5e-23 |
115 |
34% |
|
- Product
- LuxR family transcriptional regulator fused with ATPase domain
- Gene
- AMED_1177
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
77
|
C6WQ76_ACTMD (C6WQ76) |
|
(2 hsp) |
7e-23 |
114 |
31% |
|
- Product
- Transcriptional regulator, LuxR family
- Gene
- Amir_1178
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
78
|
Q7WZ88_9ACTO (Q7WZ88) |
|
|
2e-22 |
112 |
28% |
|
- Product
- Putative regulator LuxR family
- Gene
- dbv3
- Organism
- Nonomuraea sp. ATCC 39727
|
1uniprot[Pubmed] 12837387 [Medline] 22721464 The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003] |
|
79
|
A4FDP3_SACEN (A4FDP3) |
|
|
3e-22 |
112 |
40% |
|
- Product
- LuxR-family transcriptional regulator
- Gene
- nysRI
SACE_2890
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
83
|
Q6ZZH7_ACTTI (Q6ZZH7) |
|
|
2e-21 |
109 |
30% |
|
- Product
- LuxR regulatory protein
- Gene
-
- Organism
- Actinoplanes teichomyceticus
|
1uniprot[Pubmed] 15113000 Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase.(Chem. Biol.) [2004] |
|
86
|
Q70AX9_ACTTI (Q70AX9) |
|
|
1e-20 |
107 |
31% |
|
- Product
- Transcriptional regulator, LuxR family
- Gene
- tcp29
- Organism
- Actinoplanes teichomyceticus
|
1uniprot[Pubmed] 14702401 Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.(Microbiology) [2004] |
|
89
|
E2D2E3_9BACT (E2D2E3) |
|
(2 hsp) |
1e-19 |
103 |
29% |
|
- Product
- Transcriptional regulator
- Gene
-
- Organism
- uncultured soil bacterium
|
1uniprot[Pubmed] 20577994 Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.(Biopolymers) [2010] |
|
90
|
B1VT03_STRGG (B1VT03) |
|
|
2e-19 |
103 |
31% |
|
- Product
- Putative transcriptional regulator
- Gene
- SGR_878
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
92
|
Q30CS9_STRAU (Q30CS9) |
|
|
5e-19 |
102 |
29% |
|
- Product
- LipReg4
- Gene
- lipReg4
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 16723573 Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006] |
|
98
|
D7C839_STRBB (D7C839) |
|
(2 hsp) |
2e-18 |
99.8 |
28% |
|
- Product
- Putative transcriptional regulator
- Gene
- SBI_01079
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|