BLAST table : Rubra_00380

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q2PC52_STRAH
(Q2PC52)		 
[query] 1 - 5066 (5066)
[subject] 1 - 5066 (5066)
 0.0 9868   100% Putative polyketide synthase rubB Streptomyces achromogenes subsp. rubradiris
2
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 1 - 5033 (5066)
[subject] 1 - 5001 (5060)
(3 hsp)		 0.0 4291   51% Rifamycin polyketide synthase rifB
AMED_0618		 Amycolatopsis mediterranei (strain U-32)
3
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 1 - 5033 (5066)
[subject] 1 - 5001 (5060)
(3 hsp)		 0.0 4290   51% RifB rifB Amycolatopsis mediterranei
Nocardia mediterranei
4
 O52789_AMYMD
(O52789)		 
[query] 1 - 5033 (5066)
[subject] 10 - 5010 (5069)
(3 hsp)		 0.0 4289   51% Rifamycin polyketide synthase, type 1 Amycolatopsis mediterranei
Nocardia mediterranei
5
 A8M6C7_SALAI
(A8M6C7)		 
[query] 1 - 5033 (5066)
[subject] 1 - 5177 (5255)
(2 hsp)		 0.0 4277   52% Beta-ketoacyl synthase Sare_1247 Salinispora arenicola (strain CNS-205)
6
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 1 - 5033 (5066)
[subject] 1 - 5255 (5339)
(3 hsp)		 0.0 4270   51% Polyketide synthase natB Streptomyces sp. CS
7
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 4 - 5059 (5066)
[subject] 3 - 5261 (5321)
 0.0 3765   47% Polyketide synthase natC Streptomyces sp. CS
8
 E0L044_STRVO
(E0L044)		 
[query] 35 - 4568 (5066)
[subject] 1854 - 6517 (7224)
(11 hsp)		 0.0 3559   48% Beta-ketoacyl synthase StrviDRAFT_8272 Streptomyces violaceusniger Tu 4113
9
 B4VDY6_9ACTO
(B4VDY6)		 
[query] 34 - 4568 (5066)
[subject] 18 - 4661 (4894)
(5 hsp)		 0.0 3552   48% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
10
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 4 - 4569 (5066)
[subject] 3 - 4704 (5588)
(7 hsp)		 0.0 3501   47% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
11
 Q82QT4_STRAW
(Q82QT4)		 
[query] 35 - 5033 (5066)
[subject] 2552 - 7657 (7746)
(12 hsp)		 0.0 3479   45% Modular polyketide synthase pteA1
SAV419
SAV_419		 Streptomyces avermitilis
12
 A4X8L0_SALTO
(A4X8L0)		 
[query] 34 - 4565 (5066)
[subject] 1910 - 6552 (7210)
(6 hsp)		 0.0 3397   47% Beta-ketoacyl synthase Strop_2768 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
13
 D7BRD4_STRBB
(D7BRD4)		 
[query] 35 - 4589 (5066)
[subject] 2816 - 7513 (9950)
(13 hsp)		 0.0 3379   47% Short-chain dehydrogenase/reductase SDR SBI_01976 Streptomyces bingchenggensis (strain BCW-1)
14
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 31 - 4569 (5066)
[subject] 1574 - 6185 (6831)
(8 hsp)		 0.0 3368   47% ScnS1 scnS1 Streptomyces chattanoogensis
15
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 35 - 4555 (5066)
[subject] 1882 - 6454 (7110)
(7 hsp)		 0.0 3358   48% Short-chain dehydrogenase/reductase SDR Amir_2695 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
16
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 31 - 4569 (5066)
[subject] 1558 - 6149 (6797)
(8 hsp)		 0.0 3337   47% PimS1 protein
Polyketide synthase		 pimS1 Streptomyces natalensis
17
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 25 - 5038 (5066)
[subject] 5244 - 10145 (10223)
(7 hsp)		 0.0 3311   43% Polyketide synthase rapB Streptomyces hygroscopicus
18
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 33 - 4570 (5066)
[subject] 1020 - 5600 (6241)
(10 hsp)		 0.0 3303   47% Polyketide synthase KijS1 Actinomadura kijaniata
19
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 4 - 4568 (5066)
[subject] 3 - 4453 (5099)
(4 hsp)		 0.0 3295   47% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
20
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 27 - 5033 (5066)
[subject] 1780 - 6941 (10625)
(10 hsp)		 0.0 3284   45% FscC fscC Streptomyces sp. FR-008
21
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 4 - 4336 (5066)
[subject] 3 - 4474 (5214)
(6 hsp)		 0.0 3282   47% Polyketide synthase idmN Streptomyces antibioticus
22
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 1 - 4578 (5066)
[subject] 1 - 4654 (10917)
(11 hsp)		 0.0 3278   46% AmphC amphC Streptomyces nodosus
23
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 29 - 4569 (5066)
[subject] 3796 - 8362 (10827)
(19 hsp)		 0.0 3275   47% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
24
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 31 - 4568 (5066)
[subject] 4137 - 8593 (9528)
(14 hsp)		 0.0 3274   47% Type I modular polyketide synthase ttnA Streptomyces griseochromogenes
25
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 31 - 4568 (5066)
[subject] 4253 - 8713 (9648)
(14 hsp)		 0.0 3266   47% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
26
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 1 - 4568 (5066)
[subject] 1 - 4656 (10876)
(11 hsp)		 0.0 3257   47% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
27
 Q52V52_9ACTO
(Q52V52)		 
[query] 3 - 4568 (5066)
[subject] 2 - 4717 (5432)
(7 hsp)		 0.0 3256   47% Polyketide synthase type I Streptomyces aizunensis
28
 E8S0C5_MICSL
(E8S0C5)		 
[query] 24 - 4338 (5066)
[subject] 3337 - 7722 (9937)
(18 hsp)		 0.0 3243   47% Beta-ketoacyl synthase ML5_5898 Micromonospora sp. (strain L5)
29
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 1 - 4557 (5066)
[subject] 1 - 4632 (11096)
(14 hsp)		 0.0 3239   46% NysC nysC Streptomyces noursei
30
 D9T6W4_MICAI
(D9T6W4)		 
[query] 24 - 4338 (5066)
[subject] 3337 - 7721 (9936)
(18 hsp)		 0.0 3237   47% Beta-ketoacyl synthase Micau_2464 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
31
 Q0PCZ9_STRHA
(Q0PCZ9)		 Jump to Halsto_00060 
[query] 4 - 4349 (5066)
[subject] 3 - 4515 (5232)
(8 hsp)		 0.0 3232   47% Type I polyketide synthase hlsF Streptomyces halstedii
32
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 1 - 5039 (5066)
[subject] 1 - 5107 (5176)
(4 hsp)		 0.0 3219   43% ObsB Saccharopolyspora spinosa
33
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 33 - 4568 (5066)
[subject] 1024 - 5706 (6383)
(10 hsp)		 0.0 3194   44% Polyketide synthase type I mlaA1 Streptomyces sp. MP39-85
34
 Q9S0R4_STRAW
(Q9S0R4)		 Jump to Aver_00080 
[query] 1 - 4612 (5066)
[subject] 1 - 4889 (5532)
(4 hsp)		 0.0 3185   45% Type I polyketide synthase AVES 3 aveA3
SAV942
SAV_942		 Streptomyces avermitilis
35
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 33 - 4455 (5066)
[subject] 1025 - 5575 (5582)
(9 hsp)		 0.0 3167   44% Polyketide synthase type I becA Streptomyces sp. DSM 21069
36
 D9VBL5_9ACTO
(D9VBL5)		 
[query] 35 - 4102 (5066)
[subject] 982 - 4982 (5113)
(10 hsp)		 0.0 3144   48% Modular polyketide synthase SSMG_01148 Streptomyces sp. AA4
37
 D9VEY7_9ACTO
(D9VEY7)		 
[query] 32 - 4569 (5066)
[subject] 123 - 4681 (5260)
(6 hsp)		 0.0 3140   44% Modular polyketide synthase SSMG_05939 Streptomyces sp. AA4
38
 F8JUL0_STRCT
(F8JUL0)		 
[query] 35 - 4455 (5066)
[subject] 1030 - 5432 (5950)
(9 hsp)		 0.0 3118   47% Putative polyketide synthase SCAT_3270 Streptomyces cattleya
39
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 4 - 4533 (5066)
[subject] 8 - 4493 (5400)
(5 hsp)		 0.0 3113   46% Short-chain dehydrogenase/reductase SDR Amir_2684 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
40
 B5L6K8_MICCH
(B5L6K8)		 
[query] 36 - 4567 (5066)
[subject] 1023 - 5650 (6305)
(11 hsp)		 0.0 3101   44% Putative type I polyketide synthase Micromonospora chalcea
41
 F8JVX1_STRCT
(F8JVX1)		 
[query] 29 - 4335 (5066)
[subject] 1037 - 5399 (6125)
(12 hsp)		 0.0 3095   46% Putative 6-methylsalicylic acid synthase SCAT_0136 Streptomyces cattleya 2.3.1.165

2.3.1.94
42
 F8QPG1_9ACTO
(F8QPG1)		 
[query] 5 - 3453 (5066)
[subject] 4 - 3537 (3621)
(5 hsp)		 0.0 3088   53% Polyketide synthase natD Streptomyces sp. CS
43
 B3TMQ7_9ACTO
(B3TMQ7)		 
[query] 1 - 5045 (5066)
[subject] 1 - 5069 (6872)
(5 hsp)		 0.0 3082   42% Polyketide synthase KijS2 Actinomadura kijaniata
44
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 5 - 4568 (5066)
[subject] 4 - 4317 (6260)
(10 hsp)		 0.0 3082   45% Polyketide synthase rapC Streptomyces hygroscopicus
45
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 3 - 4336 (5066)
[subject] 6 - 4551 (7026)
(11 hsp)		 0.0 3080   45% Polyketide synthase pldAII Streptomyces platensis
46
 B5L6K9_MICCH
(B5L6K9)		 
[query] 35 - 4568 (5066)
[subject] 1739 - 6368 (7007)
(7 hsp)		 0.0 3077   45% Putative type I polyketide synthase Micromonospora chalcea
47
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 35 - 4609 (5066)
[subject] 4895 - 9714 (14130)
(21 hsp)		 0.0 3047   42% Type I modular polyketide synthase mlsB
MUP032c		 Mycobacterium ulcerans (strain Agy99)
48
 E8WEN5_STRFA
(E8WEN5)		 
[query] 3 - 4597 (5066)
[subject] 2 - 4535 (5156)
(4 hsp)		 0.0 3036   45% Beta-ketoacyl synthase Sfla_0979 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
49
 B1W5P4_STRGG
(B1W5P4)		 
[query] 10 - 5043 (5066)
[subject] 5 - 4772 (4843)
(2 hsp)		 0.0 3028   42% Putative type-I PKS pks3-2
SGR_6372		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
50
 D7F1M0_9ACTO
(D7F1M0)		 
[query] 1 - 4347 (5066)
[subject] 1 - 4412 (5136)
(8 hsp)		 0.0 3024   44% Polyketide synthase tsnAII Streptomyces longisporoflavus
51
 C0Z477_STRVN
(C0Z477)		 
[query] 30 - 4345 (5066)
[subject] 1056 - 5381 (6130)
(8 hsp)		 0.0 2990   46% Type I polyketide synthase, loading module and modules 1-3 ken16 Streptomyces violaceoruber
52
 A8LUX2_SALAI
(A8LUX2)		 
[query] 35 - 4345 (5066)
[subject] 991 - 5208 (7279)
(16 hsp)		 0.0 2983   46% Beta-ketoacyl synthase Sare_3156 Salinispora arenicola (strain CNS-205)
53
 F4F7F4_VERMA
(F4F7F4)		 
[query] 35 - 5033 (5066)
[subject] 955 - 5744 (5781)
(8 hsp)		 0.0 2972   43% Modular polyketide synthase VAB18032_16435 Verrucosispora maris (strain AB-18-032)
54
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 32 - 4568 (5066)
[subject] 989 - 5407 (6078)
(8 hsp)		 0.0 2972   44% ObsA Saccharopolyspora spinosa
55
 E9KTB5_STRKN
(E9KTB5)		 
[query] 24 - 4561 (5066)
[subject] 2769 - 7120 (7591)
(7 hsp)		 0.0 2965   44% Polyketide synthase fkbB
Tcs_SK_031		 Streptomyces kanamyceticus
56
 F1D8Z6_9ACTO
(F1D8Z6)		 
[query] 35 - 4561 (5066)
[subject] 2821 - 7184 (7655)
(8 hsp)		 0.0 2962   45% FkbB Streptomyces sp. MJM7001
57
 B6CLY1_9MYCO
(B6CLY1)		 
[query] 35 - 4593 (5066)
[subject] 4890 - 9713 (12352)
(19 hsp)		 0.0 2959   41% Type I modular polyketide synthase, MlsB mlsB
MULP_051		 Mycobacterium liflandii 128FXT
58
 E9KTI2_9ACTO
(E9KTI2)		 
[query] 35 - 4561 (5066)
[subject] 2812 - 7175 (7646)
(8 hsp)		 0.0 2959   45% Polyketide synthase fkbB
Tcs_11604BP_028		 Streptomyces sp. KCTC 11604BP
59
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 1 - 4336 (5066)
[subject] 1 - 4258 (8301)
(9 hsp)		 0.0 2888   46% Type I polyketide synthase sfaH Streptomyces flaveolus
60
 C6K7D8_9ACTO
(C6K7D8)		 
[query] 32 - 5033 (5066)
[subject] 3147 - 7858 (7938)
(8 hsp)		 0.0 2863   41% Polyketide synthase rapA Actinoplanes sp. N902-109
61
 D7P611_CHOCO
(D7P611)		 
[query] 470 - 4555 (5066)
[subject] 978 - 5230 (6255)
(11 hsp)		 0.0 2802   44% TugA tugA Chondromyces crocatus
62
 Q9KIE0_STRHY
(Q9KIE0)		 Jump to Asco_00140 
[query] 33 - 5033 (5066)
[subject] 1159 - 5941 (7525)
(7 hsp)		 0.0 2799   41% FkbB fkbB Streptomyces hygroscopicus subsp. ascomyceticus
63
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 37 - 4609 (5066)
[subject] 20 - 4849 (16990)
(31 hsp)		 0.0 2750   39% Type I modular polyketide synthase mlsA1
MUP040c		 Mycobacterium ulcerans (strain Agy99)
64
 C3VLZ7_9ACTO
(C3VLZ7)		 
[query] 3 - 3464 (5066)
[subject] 5 - 3298 (3373)
(3 hsp)		 0.0 2737   48% Polyketide synthase type I mlaF Streptomyces sp. MP39-85
65
 A8M6D0_SALAI
(A8M6D0)		 
[query] 4 - 3454 (5066)
[subject] 3 - 3482 (3494)
(3 hsp)		 0.0 2724   49% Acyl transferase Sare_1250 Salinispora arenicola (strain CNS-205)
66
 D8HZ86_AMYMU
(D8HZ86)		 
[query] 4 - 3453 (5066)
[subject] 3 - 3409 (3413)
(2 hsp)		 0.0 2722   49% Rifamycin polyketide synthase rifE
AMED_0621		 Amycolatopsis mediterranei (strain U-32)
67
 O54593_AMYMD
(O54593)		 Jump to Rifam_00250 
[query] 4 - 3453 (5066)
[subject] 3 - 3409 (3413)
(2 hsp)		 0.0 2722   49% RifE
Rifamycin polyketide synthase, type 1		 rifE Amycolatopsis mediterranei
Nocardia mediterranei
68
 C5HV15_STRAT
(C5HV15)		 Jump to Indano_00170 
[query] 4 - 3473 (5066)
[subject] 5 - 3510 (3596)
(4 hsp)		 0.0 2722   48% Polyketide synthase idmM Streptomyces antibioticus
69
 B6CLY8_9MYCO
(B6CLY8)		 
[query] 37 - 4593 (5066)
[subject] 20 - 4831 (17019)
(32 hsp)		 0.0 2721   39% Type I modular polyketide synthase, MlsA1 mlsA1
MULP_065		 Mycobacterium liflandii 128FXT
70
 E8WEN9_STRFA
(E8WEN9)		 
[query] 1 - 3458 (5066)
[subject] 1 - 3425 (3511)
(3 hsp)		 0.0 2720   49% Mycocerosate synthase, 6-deoxyerythronolide-B synthase Sfla_0983 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD) 2.3.1.111

2.3.1.94
71
 Q0RIF5_FRAAA
(Q0RIF5)		 
[query] 33 - 4569 (5066)
[subject] 1010 - 5719 (6432)
(12 hsp)		 0.0 2716   42% Putative type I polyketide synthase FRAAL4072 Frankia alni (strain ACN14a) 2.3.1.-
72
 Q9ZGA4_9ACTO
(Q9ZGA4)		 
[query] 35 - 4555 (5066)
[subject] 1183 - 5464 (7576)
(9 hsp)		 0.0 2713   42% FK506 polyketide synthase fkbB Streptomyces sp. MA6548
73
 Q52V50_9ACTO
(Q52V50)		 
[query] 35 - 3453 (5066)
[subject] 3931 - 7427 (7510)
(12 hsp)		 0.0 2706   49% Polyketide synthase type I Streptomyces aizunensis
74
 Q0R4M8_STRAT
(Q0R4M8)		 Jump to Chth_00260 
[query] 33 - 3460 (5066)
[subject] 1085 - 4617 (4699)
(9 hsp)		 0.0 2683   48% ChlA1 Streptomyces antibioticus
75
 Q52V53_9ACTO
(Q52V53)		 
[query] 35 - 3457 (5066)
[subject] 1601 - 5131 (5207)
(8 hsp)		 0.0 2681   48% Polyketide synthase type I Streptomyces aizunensis
76
 Q52V49_9ACTO
(Q52V49)		 
[query] 4 - 3494 (5066)
[subject] 2 - 3618 (3872)
(5 hsp)		 0.0 2677   48% Polyketide synthase type I Streptomyces aizunensis
77
 F8AWN2_9ACTO
(F8AWN2)		 
[query] 33 - 3879 (5066)
[subject] 1233 - 5425 (6077)
(14 hsp)		 0.0 2671   44% (Acyl-carrier-protein) S-acetyltransferase., 6-deoxyerythronolide-B synthase FsymDg_1936 Frankia symbiont of Datisca glomerata 2.3.1.38

2.3.1.94
78
 F8QPG2_9ACTO
(F8QPG2)		 
[query] 1 - 3458 (5066)
[subject] 1 - 3525 (3533)
(4 hsp)		 0.0 2660   48% Polyketide synthase natE Streptomyces sp. CS
79
 Q30CS1_STRAU
(Q30CS1)		 Jump to Alip_00140 
[query] 5 - 3455 (5066)
[subject] 4 - 3505 (3582)
(4 hsp)		 0.0 2660   48% LipPks2 lipPks2 Streptomyces aureofaciens
80
 C3VLW9_9ACTO
(C3VLW9)		 
[query] 3 - 3453 (5066)
[subject] 5 - 3290 (3377)
(3 hsp)		 0.0 2658   48% Polyketide synthase type I becF Streptomyces sp. DSM 21069
81
 B4VB11_9ACTO
(B4VB11)		 
[query] 33 - 3463 (5066)
[subject] 335 - 3853 (3928)
(5 hsp)		 0.0 2656   49% Polyketide synthase type I SSAG_04921 Streptomyces sp. Mg1
82
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 30 - 3453 (5066)
[subject] 3763 - 7196 (7488)
(10 hsp)		 0.0 2647   49% ObsC Saccharopolyspora spinosa
83
 B4ER95_STRON
(B4ER95)		 
[query] 3 - 3453 (5066)
[subject] 2 - 3537 (3625)
(5 hsp)		 0.0 2639   48% Protein modular polyketide synthase NorA' norA' Streptoverticillium orinoci
84
 Q30CS0_STRAU
(Q30CS0)		 Jump to Alip_00150 
[query] 3 - 3450 (5066)
[subject] 2 - 3531 (3612)
(5 hsp)		 0.0 2637   47% LipPks3 lipPks3 Streptomyces aureofaciens
85
 E0D206_9ACTO
(E0D206)		 Jump to FD891_00050 
[query] 3 - 3458 (5066)
[subject] 2 - 3499 (3799)
(4 hsp)		 0.0 2636   47% Polyketide synthase gfsE Streptomyces graminofaciens
86
 Q0PD02_STRHA
(Q0PD02)		 Jump to Halsto_00030 
[query] 33 - 3457 (5066)
[subject] 1591 - 5138 (5220)
(10 hsp)		 0.0 2628   47% Type I polyketide synthase hlsC Streptomyces halstedii
87
 Q93H87_STRAW
(Q93H87)		 
[query] 35 - 3449 (5066)
[subject] 2552 - 5959 (6048)
(13 hsp)		 0.0 2602   47% Modular polyketide synthase pteA1 Streptomyces avermitilis
88
 C1B9P9_RHOOB
(C1B9P9)		 
[query] 5 - 3453 (5066)
[subject] 4 - 3454 (3527)
(4 hsp)		 0.0 2571   46% Polyketide synthase ROP_41550 Rhodococcus opacus (strain B4)
89
 D7F1M1_9ACTO
(D7F1M1)		 
[query] 31 - 3483 (5066)
[subject] 2090 - 5587 (5630)
(7 hsp)		 0.0 2567   46% Polyketide synthase tsnAIII Streptomyces longisporoflavus
90
 Q0S8W4_RHOSR
(Q0S8W4)		 
[query] 5 - 3453 (5066)
[subject] 4 - 3454 (3527)
(4 hsp)		 0.0 2546   46% Type I polyketide synthase RHA1_ro04231 Rhodococcus sp. (strain RHA1)
91
 Q0R4M5_STRAT
(Q0R4M5)		 Jump to Chth_00290 
[query] 31 - 3458 (5066)
[subject] 2139 - 5635 (5718)
(9 hsp)		 0.0 2521   45% ChlA3 Streptomyces antibioticus
92
 Q8CJN6_STRCO
(Q8CJN6)		 
[query] 31 - 3454 (5066)
[subject] 1012 - 4479 (4557)
(8 hsp)		 0.0 2515   46% Putative type I polyketide synthase SCO6275 Streptomyces coelicolor
93
 D6EJM4_STRLI
(D6EJM4)		 
[query] 31 - 3454 (5066)
[subject] 1056 - 4521 (4599)
(8 hsp)		 0.0 2512   46% Type I polyketide synthase SSPG_01356 Streptomyces lividans TK24
94
 E0D205_9ACTO
(E0D205)		 Jump to FD891_00040 
[query] 4 - 3453 (5066)
[subject] 3 - 3542 (3639)
(5 hsp)		 0.0 2500   45% Polyketide synthase gfsD Streptomyces graminofaciens
95
 Q1MX73_9ACTO
(Q1MX73)		 Jump to Tetrn_00160 
[query] 4 - 3451 (5066)
[subject] 2078 - 5573 (5657)
(7 hsp)		 0.0 2494   45% Type I polyketide synthase tmnAIV Streptomyces sp. NRRL 11266
96
 C3VLZ4_9ACTO
(C3VLZ4)		 
[query] 1 - 3462 (5066)
[subject] 1 - 3292 (3365)
(4 hsp)		 0.0 2484   46% Polyketide synthase type I mlaD Streptomyces sp. MP39-85
97
 A4X8M0_SALTO
(A4X8M0)		 
[query] 4 - 3453 (5066)
[subject] 3 - 3428 (3711)
(5 hsp)		 0.0 2478   46% Beta-ketoacyl synthase Strop_2778 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
98
 Q9EX53_STRCO
(Q9EX53)		 
[query] 4 - 3474 (5066)
[subject] 3 - 3504 (3576)
(4 hsp)		 0.0 2474   45% Putative type I polyketide synthase SCO6274 Streptomyces coelicolor
99
 D9WQL2_9ACTO
(D9WQL2)		 
[query] 1 - 3446 (5066)
[subject] 1 - 3283 (3284)
(3 hsp)		 0.0 2472   46% Modular polyketide synthase SSOG_07859 Streptomyces himastatinicus ATCC 53653
100
 D9W5N3_9ACTO
(D9W5N3)		 
[query] 35 - 3111 (5066)
[subject] 603 - 3731 (4488)
(12 hsp)		 0.0 2472   50% Lasalocid modular polyketide synthase SSNG_07463 Streptomyces sp. C
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 Q2PC52_STRAH
(Q2PC52)		 
[query] 1 - 5066 (5066)
[subject] 1 - 5066 (5066)
 0.0 9868   100%
Product
Putative polyketide synthase
Gene
rubB
Organism
Streptomyces achromogenes subsp. rubradiris
1uniprot[Pubmed] 9387157 [Medline] 98048398
Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997]
2uniprot[Pubmed] 12889805 [Medline] 22771458
Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003]
[pubmed all]
2
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 1 - 5033 (5066)
[subject] 1 - 5001 (5060)
(3 hsp)		 0.0 4291   51%
Product
Rifamycin polyketide synthase
Gene
rifB
AMED_0618
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
3
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 1 - 5033 (5066)
[subject] 1 - 5001 (5060)
(3 hsp)		 0.0 4290   51%
Product
RifB
Gene
rifB
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
6
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 1 - 5033 (5066)
[subject] 1 - 5255 (5339)
(3 hsp)		 0.0 4270   51%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
7
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 4 - 5059 (5066)
[subject] 3 - 5261 (5321)
 0.0 3765   47%
Product
Polyketide synthase
Gene
natC
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
10
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 4 - 4569 (5066)
[subject] 3 - 4704 (5588)
(7 hsp)		 0.0 3501   47%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
11
 Q82QT4_STRAW
(Q82QT4)		 
[query] 35 - 5033 (5066)
[subject] 2552 - 7657 (7746)
(12 hsp)		 0.0 3479   45%
Product
Modular polyketide synthase
Gene
pteA1
SAV419
SAV_419
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
13
 D7BRD4_STRBB
(D7BRD4)		 
[query] 35 - 4589 (5066)
[subject] 2816 - 7513 (9950)
(13 hsp)		 0.0 3379   47%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_01976
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
14
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 31 - 4569 (5066)
[subject] 1574 - 6185 (6831)
(8 hsp)		 0.0 3368   47%
Product
ScnS1
Gene
scnS1
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
15
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 35 - 4555 (5066)
[subject] 1882 - 6454 (7110)
(7 hsp)		 0.0 3358   48%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2695
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
16
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 31 - 4569 (5066)
[subject] 1558 - 6149 (6797)
(8 hsp)		 0.0 3337   47%
Product
PimS1 protein
Polyketide synthase
Gene
pimS1
Organism
Streptomyces natalensis
1uniprot[Pubmed] 10187796 [Medline] 99214571
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999]
2uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
[pubmed all]
17
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 25 - 5038 (5066)
[subject] 5244 - 10145 (10223)
(7 hsp)		 0.0 3311   43%
Product
Polyketide synthase
Gene
rapB
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
18
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 33 - 4570 (5066)
[subject] 1020 - 5600 (6241)
(10 hsp)		 0.0 3303   47%
Product
Polyketide synthase
Gene
KijS1
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
19
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 4 - 4568 (5066)
[subject] 3 - 4453 (5099)
(4 hsp)		 0.0 3295   47%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
20
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 27 - 5033 (5066)
[subject] 1780 - 6941 (10625)
(10 hsp)		 0.0 3284   45%
Product
FscC
Gene
fscC
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
21
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 4 - 4336 (5066)
[subject] 3 - 4474 (5214)
(6 hsp)		 0.0 3282   47%
Product
Polyketide synthase
Gene
idmN
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
22
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 1 - 4578 (5066)
[subject] 1 - 4654 (10917)
(11 hsp)		 0.0 3278   46%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
23
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 29 - 4569 (5066)
[subject] 3796 - 8362 (10827)
(19 hsp)		 0.0 3275   47%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
24
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 31 - 4568 (5066)
[subject] 4137 - 8593 (9528)
(14 hsp)		 0.0 3274   47%
Product
Type I modular polyketide synthase
Gene
ttnA
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
25
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 31 - 4568 (5066)
[subject] 4253 - 8713 (9648)
(14 hsp)		 0.0 3266   47%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
26
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 1 - 4568 (5066)
[subject] 1 - 4656 (10876)
(11 hsp)		 0.0 3257   47%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
27
 Q52V52_9ACTO
(Q52V52)		 
[query] 3 - 4568 (5066)
[subject] 2 - 4717 (5432)
(7 hsp)		 0.0 3256   47%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
29
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 1 - 4557 (5066)
[subject] 1 - 4632 (11096)
(14 hsp)		 0.0 3239   46%
Product
NysC
Gene
nysC
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
32
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 1 - 5039 (5066)
[subject] 1 - 5107 (5176)
(4 hsp)		 0.0 3219   43%
Product
ObsB
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
33
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 33 - 4568 (5066)
[subject] 1024 - 5706 (6383)
(10 hsp)		 0.0 3194   44%
Product
Polyketide synthase type I
Gene
mlaA1
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
34
 Q9S0R4_STRAW
(Q9S0R4)		 Jump to Aver_00080 
[query] 1 - 4612 (5066)
[subject] 1 - 4889 (5532)
(4 hsp)		 0.0 3185   45%
Product
Type I polyketide synthase AVES 3
Gene
aveA3
SAV942
SAV_942
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 10449723 [Medline] 99380548
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999]
2uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
3uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
35
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 33 - 4455 (5066)
[subject] 1025 - 5575 (5582)
(9 hsp)		 0.0 3167   44%
Product
Polyketide synthase type I
Gene
becA
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
39
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 4 - 4533 (5066)
[subject] 8 - 4493 (5400)
(5 hsp)		 0.0 3113   46%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2684
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
40
 B5L6K8_MICCH
(B5L6K8)		 
[query] 36 - 4567 (5066)
[subject] 1023 - 5650 (6305)
(11 hsp)		 0.0 3101   44%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
42
 F8QPG1_9ACTO
(F8QPG1)		 
[query] 5 - 3453 (5066)
[subject] 4 - 3537 (3621)
(5 hsp)		 0.0 3088   53%
Product
Polyketide synthase
Gene
natD
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
43
 B3TMQ7_9ACTO
(B3TMQ7)		 
[query] 1 - 5045 (5066)
[subject] 1 - 5069 (6872)
(5 hsp)		 0.0 3082   42%
Product
Polyketide synthase
Gene
KijS2
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
44
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 5 - 4568 (5066)
[subject] 4 - 4317 (6260)
(10 hsp)		 0.0 3082   45%
Product
Polyketide synthase
Gene
rapC
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
45
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 3 - 4336 (5066)
[subject] 6 - 4551 (7026)
(11 hsp)		 0.0 3080   45%
Product
Polyketide synthase
Gene
pldAII
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
46
 B5L6K9_MICCH
(B5L6K9)		 
[query] 35 - 4568 (5066)
[subject] 1739 - 6368 (7007)
(7 hsp)		 0.0 3077   45%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
47
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 35 - 4609 (5066)
[subject] 4895 - 9714 (14130)
(21 hsp)		 0.0 3047   42%
Product
Type I modular polyketide synthase
Gene
mlsB
MUP032c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
2uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
[pubmed all]
49
 B1W5P4_STRGG
(B1W5P4)		 
[query] 10 - 5043 (5066)
[subject] 5 - 4772 (4843)
(2 hsp)		 0.0 3028   42%
Product
Putative type-I PKS
Gene
pks3-2
SGR_6372
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
53
 F4F7F4_VERMA
(F4F7F4)		 
[query] 35 - 5033 (5066)
[subject] 955 - 5744 (5781)
(8 hsp)		 0.0 2972   43%
Product
Modular polyketide synthase
Gene
VAB18032_16435
Organism
Verrucosispora maris (strain AB-18-032)
1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]
54
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 32 - 4568 (5066)
[subject] 989 - 5407 (6078)
(8 hsp)		 0.0 2972   44%
Product
ObsA
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
55
 E9KTB5_STRKN
(E9KTB5)		 
[query] 24 - 4561 (5066)
[subject] 2769 - 7120 (7591)
(7 hsp)		 0.0 2965   44%
Product
Polyketide synthase
Gene
fkbB
Tcs_SK_031
Organism
Streptomyces kanamyceticus
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
57
 B6CLY1_9MYCO
(B6CLY1)		 
[query] 35 - 4593 (5066)
[subject] 4890 - 9713 (12352)
(19 hsp)		 0.0 2959   41%
Product
Type I modular polyketide synthase, MlsB
Gene
mlsB
MULP_051
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
58
 E9KTI2_9ACTO
(E9KTI2)		 
[query] 35 - 4561 (5066)
[subject] 2812 - 7175 (7646)
(8 hsp)		 0.0 2959   45%
Product
Polyketide synthase
Gene
fkbB
Tcs_11604BP_028
Organism
Streptomyces sp. KCTC 11604BP
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
59
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 1 - 4336 (5066)
[subject] 1 - 4258 (8301)
(9 hsp)		 0.0 2888   46%
Product
Type I polyketide synthase
Gene
sfaH
Organism
Streptomyces flaveolus
1uniprot
Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010]
61
 D7P611_CHOCO
(D7P611)		 
[query] 470 - 4555 (5066)
[subject] 978 - 5230 (6255)
(11 hsp)		 0.0 2802   44%
Product
TugA
Gene
tugA
Organism
Chondromyces crocatus
1uniprot[Pubmed] 20416506
Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010]
62
 Q9KIE0_STRHY
(Q9KIE0)		 Jump to Asco_00140 
[query] 33 - 5033 (5066)
[subject] 1159 - 5941 (7525)
(7 hsp)		 0.0 2799   41%
Product
FkbB
Gene
fkbB
Organism
Streptomyces hygroscopicus subsp. ascomyceticus
1uniprot[Pubmed] 10863099 [Medline] 20323220
The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.(Gene) [2000]
63
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 37 - 4609 (5066)
[subject] 20 - 4849 (16990)
(31 hsp)		 0.0 2750   39%
Product
Type I modular polyketide synthase
Gene
mlsA1
MUP040c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
2uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
[pubmed all]
64
 C3VLZ7_9ACTO
(C3VLZ7)		 
[query] 3 - 3464 (5066)
[subject] 5 - 3298 (3373)
(3 hsp)		 0.0 2737   48%
Product
Polyketide synthase type I
Gene
mlaF
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
66
 D8HZ86_AMYMU
(D8HZ86)		 
[query] 4 - 3453 (5066)
[subject] 3 - 3409 (3413)
(2 hsp)		 0.0 2722   49%
Product
Rifamycin polyketide synthase
Gene
rifE
AMED_0621
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
67
 O54593_AMYMD
(O54593)		 Jump to Rifam_00250 
[query] 4 - 3453 (5066)
[subject] 3 - 3409 (3413)
(2 hsp)		 0.0 2722   49%
Product
RifE
Rifamycin polyketide synthase, type 1
Gene
rifE
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
68
 C5HV15_STRAT
(C5HV15)		 Jump to Indano_00170 
[query] 4 - 3473 (5066)
[subject] 5 - 3510 (3596)
(4 hsp)		 0.0 2722   48%
Product
Polyketide synthase
Gene
idmM
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
69
 B6CLY8_9MYCO
(B6CLY8)		 
[query] 37 - 4593 (5066)
[subject] 20 - 4831 (17019)
(32 hsp)		 0.0 2721   39%
Product
Type I modular polyketide synthase, MlsA1
Gene
mlsA1
MULP_065
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
71
 Q0RIF5_FRAAA
(Q0RIF5)		 
[query] 33 - 4569 (5066)
[subject] 1010 - 5719 (6432)
(12 hsp)		 0.0 2716   42%
Product
Putative type I polyketide synthase
Gene
FRAAL4072
Organism
Frankia alni (strain ACN14a)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
72
 Q9ZGA4_9ACTO
(Q9ZGA4)		 
[query] 35 - 4555 (5066)
[subject] 1183 - 5464 (7576)
(9 hsp)		 0.0 2713   42%
Product
FK506 polyketide synthase
Gene
fkbB
Organism
Streptomyces sp. MA6548
1uniprot[Pubmed] 9780228 [Medline] 98451508
The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506.(Eur. J. Biochem.) [1998]
73
 Q52V50_9ACTO
(Q52V50)		 
[query] 35 - 3453 (5066)
[subject] 3931 - 7427 (7510)
(12 hsp)		 0.0 2706   49%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
74
 Q0R4M8_STRAT
(Q0R4M8)		 Jump to Chth_00260 
[query] 33 - 3460 (5066)
[subject] 1085 - 4617 (4699)
(9 hsp)		 0.0 2683   48%
Product
ChlA1
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
75
 Q52V53_9ACTO
(Q52V53)		 
[query] 35 - 3457 (5066)
[subject] 1601 - 5131 (5207)
(8 hsp)		 0.0 2681   48%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
76
 Q52V49_9ACTO
(Q52V49)		 
[query] 4 - 3494 (5066)
[subject] 2 - 3618 (3872)
(5 hsp)		 0.0 2677   48%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
78
 F8QPG2_9ACTO
(F8QPG2)		 
[query] 1 - 3458 (5066)
[subject] 1 - 3525 (3533)
(4 hsp)		 0.0 2660   48%
Product
Polyketide synthase
Gene
natE
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
79
 Q30CS1_STRAU
(Q30CS1)		 Jump to Alip_00140 
[query] 5 - 3455 (5066)
[subject] 4 - 3505 (3582)
(4 hsp)		 0.0 2660   48%
Product
LipPks2
Gene
lipPks2
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 16723573
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006]
80
 C3VLW9_9ACTO
(C3VLW9)		 
[query] 3 - 3453 (5066)
[subject] 5 - 3290 (3377)
(3 hsp)		 0.0 2658   48%
Product
Polyketide synthase type I
Gene
becF
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
82
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 30 - 3453 (5066)
[subject] 3763 - 7196 (7488)
(10 hsp)		 0.0 2647   49%
Product
ObsC
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
84
 Q30CS0_STRAU
(Q30CS0)		 Jump to Alip_00150 
[query] 3 - 3450 (5066)
[subject] 2 - 3531 (3612)
(5 hsp)		 0.0 2637   47%
Product
LipPks3
Gene
lipPks3
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 16723573
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006]
85
 E0D206_9ACTO
(E0D206)		 Jump to FD891_00050 
[query] 3 - 3458 (5066)
[subject] 2 - 3499 (3799)
(4 hsp)		 0.0 2636   47%
Product
Polyketide synthase
Gene
gfsE
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
87
 Q93H87_STRAW
(Q93H87)		 
[query] 35 - 3449 (5066)
[subject] 2552 - 5959 (6048)
(13 hsp)		 0.0 2602   47%
Product
Modular polyketide synthase
Gene
pteA1
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
90
 Q0S8W4_RHOSR
(Q0S8W4)		 
[query] 5 - 3453 (5066)
[subject] 4 - 3454 (3527)
(4 hsp)		 0.0 2546   46%
Product
Type I polyketide synthase
Gene
RHA1_ro04231
Organism
Rhodococcus sp. (strain RHA1)
1uniprot[Pubmed] 17030794
The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse.(Proc. Natl. Acad. Sci. U.S.A.) [2006]
91
 Q0R4M5_STRAT
(Q0R4M5)		 Jump to Chth_00290 
[query] 31 - 3458 (5066)
[subject] 2139 - 5635 (5718)
(9 hsp)		 0.0 2521   45%
Product
ChlA3
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
92
 Q8CJN6_STRCO
(Q8CJN6)		 
[query] 31 - 3454 (5066)
[subject] 1012 - 4479 (4557)
(8 hsp)		 0.0 2515   46%
Product
Putative type I polyketide synthase
Gene
SCO6275
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
94
 E0D205_9ACTO
(E0D205)		 Jump to FD891_00040 
[query] 4 - 3453 (5066)
[subject] 3 - 3542 (3639)
(5 hsp)		 0.0 2500   45%
Product
Polyketide synthase
Gene
gfsD
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
96
 C3VLZ4_9ACTO
(C3VLZ4)		 
[query] 1 - 3462 (5066)
[subject] 1 - 3292 (3365)
(4 hsp)		 0.0 2484   46%
Product
Polyketide synthase type I
Gene
mlaD
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
98
 Q9EX53_STRCO
(Q9EX53)		 
[query] 4 - 3474 (5066)
[subject] 3 - 3504 (3576)
(4 hsp)		 0.0 2474   45%
Product
Putative type I polyketide synthase
Gene
SCO6274
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]