BLAST table : Aver_00080

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q9S0R4_STRAW
(Q9S0R4)		 
[query] 1 - 5532 (5532)
[subject] 1 - 5532 (5532)
 0.0 10930   100% Type I polyketide synthase AVES 3 aveA3
SAV942
SAV_942		 Streptomyces avermitilis
2
 A8J704_9ACTO
(A8J704)		 
[query] 1470 - 5528 (5532)
[subject] 1704 - 5672 (5674)
(5 hsp)		 0.0 4496   64% Modular polyketide synthase nemA3 Streptomyces cyaneogriseus subsp. noncyanogenus
3
 E0L044_STRVO
(E0L044)		 
[query] 38 - 5519 (5532)
[subject] 1854 - 7205 (7224)
(6 hsp)		 0.0 4387   49% Beta-ketoacyl synthase StrviDRAFT_8272 Streptomyces violaceusniger Tu 4113
4
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 36 - 5529 (5532)
[subject] 1020 - 6240 (6241)
(5 hsp)		 0.0 4373   50% Polyketide synthase KijS1 Actinomadura kijaniata
5
 Q82QT4_STRAW
(Q82QT4)		 
[query] 38 - 5529 (5532)
[subject] 2552 - 7745 (7746)
(10 hsp)		 0.0 4332   49% Modular polyketide synthase pteA1
SAV419
SAV_419		 Streptomyces avermitilis
6
 A4X8L0_SALTO
(A4X8L0)		 
[query] 36 - 5527 (5532)
[subject] 1909 - 7206 (7210)
(4 hsp)		 0.0 4296   48% Beta-ketoacyl synthase Strop_2768 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
7
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 4 - 5438 (5532)
[subject] 3 - 5290 (5588)
(4 hsp)		 0.0 4286   48% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
8
 B4VDY6_9ACTO
(B4VDY6)		 
[query] 30 - 5023 (5532)
[subject] 11 - 4851 (4894)
(2 hsp)		 0.0 4252   51% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
9
 Q52V52_9ACTO
(Q52V52)		 
[query] 3 - 5528 (5532)
[subject] 2 - 5430 (5432)
 0.0 4251   48% Polyketide synthase type I Streptomyces aizunensis
10
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 1 - 5529 (5532)
[subject] 1 - 5338 (5339)
 0.0 4236   48% Polyketide synthase natB Streptomyces sp. CS
11
 D9T6W4_MICAI
(D9T6W4)		 
[query] 38 - 5438 (5532)
[subject] 1593 - 6819 (9936)
(13 hsp)		 0.0 4221   49% Beta-ketoacyl synthase Micau_2464 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
12
 E8S0C5_MICSL
(E8S0C5)		 
[query] 38 - 5438 (5532)
[subject] 1593 - 6819 (9937)
(14 hsp)		 0.0 4216   49% Beta-ketoacyl synthase ML5_5898 Micromonospora sp. (strain L5)
13
 B5L6K8_MICCH
(B5L6K8)		 
[query] 39 - 5528 (5532)
[subject] 1023 - 6303 (6305)
(6 hsp)		 0.0 4205   48% Putative type I polyketide synthase Micromonospora chalcea
14
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 31 - 5529 (5532)
[subject] 1571 - 6830 (6831)
(6 hsp)		 0.0 4179   48% ScnS1 scnS1 Streptomyces chattanoogensis
15
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 28 - 5527 (5532)
[subject] 1872 - 7106 (7110)
(4 hsp)		 0.0 4177   49% Short-chain dehydrogenase/reductase SDR Amir_2695 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
16
 D7BRD4_STRBB
(D7BRD4)		 
[query] 44 - 5529 (5532)
[subject] 4604 - 9949 (9950)
(7 hsp)		 0.0 4164   48% Short-chain dehydrogenase/reductase SDR SBI_01976 Streptomyces bingchenggensis (strain BCW-1)
17
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 38 - 5529 (5532)
[subject] 5575 - 10916 (10917)
(7 hsp)		 0.0 4130   47% AmphC amphC Streptomyces nodosus
18
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 31 - 5529 (5532)
[subject] 1555 - 6796 (6797)
(6 hsp)		 0.0 4116   48% PimS1 protein
Polyketide synthase		 pimS1 Streptomyces natalensis
19
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 4 - 5529 (5532)
[subject] 3 - 5098 (5099)
 0.0 4099   47% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
20
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 1 - 5442 (5532)
[subject] 1 - 5009 (5060)
(2 hsp)		 0.0 4065   48% Rifamycin polyketide synthase rifB
AMED_0618		 Amycolatopsis mediterranei (strain U-32)
21
 O52789_AMYMD
(O52789)		 
[query] 1 - 5442 (5532)
[subject] 10 - 5018 (5069)
(2 hsp)		 0.0 4063   48% Rifamycin polyketide synthase, type 1 Amycolatopsis mediterranei
Nocardia mediterranei
22
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 1 - 5442 (5532)
[subject] 1 - 5009 (5060)
(2 hsp)		 0.0 4063   48% RifB rifB Amycolatopsis mediterranei
Nocardia mediterranei
23
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 35 - 5528 (5532)
[subject] 28 - 5320 (5321)
 0.0 4041   48% Polyketide synthase natC Streptomyces sp. CS
24
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 36 - 5529 (5532)
[subject] 1024 - 6382 (6383)
(7 hsp)		 0.0 4018   45% Polyketide synthase type I mlaA1 Streptomyces sp. MP39-85
25
 A8M6C7_SALAI
(A8M6C7)		 
[query] 1 - 5453 (5532)
[subject] 1 - 5192 (5255)
(2 hsp)		 0.0 4017   48% Beta-ketoacyl synthase Sare_1247 Salinispora arenicola (strain CNS-205)
26
 D6C477_9ACTO
(D6C477)		 Jump to Meili_00310 
[query] 1488 - 5527 (5532)
[subject] 1789 - 5819 (5822)
(6 hsp)		 0.0 3989   57% Modular polyketide synthase meiA3 Streptomyces nanchangensis
27
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 36 - 5441 (5532)
[subject] 1786 - 6948 (10625)
(7 hsp)		 0.0 3982   48% FscC fscC Streptomyces sp. FR-008
28
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 31 - 5504 (5532)
[subject] 5577 - 10837 (10876)
(5 hsp)		 0.0 3972   48% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
29
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 35 - 5528 (5532)
[subject] 5251 - 10219 (10223)
(4 hsp)		 0.0 3968   46% Polyketide synthase rapB Streptomyces hygroscopicus
30
 B5L6K9_MICCH
(B5L6K9)		 
[query] 31 - 5439 (5532)
[subject] 1732 - 6934 (7007)
(3 hsp)		 0.0 3957   47% Putative type I polyketide synthase Micromonospora chalcea
31
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 1 - 5526 (5532)
[subject] 1 - 5176 (5176)
 0.0 3900   46% ObsB Saccharopolyspora spinosa
32
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 4 - 5438 (5532)
[subject] 8 - 5110 (5400)
(2 hsp)		 0.0 3852   47% Short-chain dehydrogenase/reductase SDR Amir_2684 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
33
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 31 - 5081 (5532)
[subject] 3795 - 8586 (10827)
(17 hsp)		 0.0 3818   49% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
34
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 1 - 5069 (5532)
[subject] 1 - 4914 (11096)
(10 hsp)		 0.0 3817   48% NysC nysC Streptomyces noursei
35
 D9VEY7_9ACTO
(D9VEY7)		 
[query] 31 - 5438 (5532)
[subject] 119 - 5215 (5260)
(3 hsp)		 0.0 3769   45% Modular polyketide synthase SSMG_05939 Streptomyces sp. AA4
36
 D1XUK5_9ACTO
(D1XUK5)		 
[query] 3 - 5450 (5532)
[subject] 2 - 5088 (5157)
 0.0 3761   46% Short-chain dehydrogenase/reductase SDR SACTEDRAFT_6365 Streptomyces sp. SA3_actE
37
 D7F1M0_9ACTO
(D7F1M0)		 
[query] 3 - 4573 (5532)
[subject] 4 - 4401 (5136)
(6 hsp)		 0.0 3745   49% Polyketide synthase tsnAII Streptomyces longisporoflavus
38
 Q0PCZ9_STRHA
(Q0PCZ9)		 Jump to Halsto_00060 
[query] 4 - 4585 (5532)
[subject] 3 - 4516 (5232)
(6 hsp)		 0.0 3731   49% Type I polyketide synthase hlsF Streptomyces halstedii
39
 E8WEN5_STRFA
(E8WEN5)		 
[query] 3 - 5438 (5532)
[subject] 2 - 5075 (5156)
(2 hsp)		 0.0 3725   46% Beta-ketoacyl synthase Sfla_0979 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
40
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 2 - 4569 (5532)
[subject] 5 - 4557 (7026)
(6 hsp)		 0.0 3680   49% Polyketide synthase pldAII Streptomyces platensis
41
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 36 - 5067 (5532)
[subject] 4139 - 8783 (9528)
(12 hsp)		 0.0 3675   47% Type I modular polyketide synthase ttnA Streptomyces griseochromogenes
42
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 36 - 5067 (5532)
[subject] 4255 - 8903 (9648)
(11 hsp)		 0.0 3665   47% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
43
 B3TMQ7_9ACTO
(B3TMQ7)		 
[query] 5 - 5268 (5532)
[subject] 2 - 4958 (6872)
(5 hsp)		 0.0 3634   46% Polyketide synthase KijS2 Actinomadura kijaniata
44
 F8JUL0_STRCT
(F8JUL0)		 
[query] 38 - 4700 (5532)
[subject] 1030 - 5432 (5950)
(9 hsp)		 0.0 3628   50% Putative polyketide synthase SCAT_3270 Streptomyces cattleya
45
 B1W5P4_STRGG
(B1W5P4)		 
[query] 3 - 5524 (5532)
[subject] 2 - 4838 (4843)
 0.0 3547   44% Putative type-I PKS pks3-2
SGR_6372		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
46
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 36 - 4701 (5532)
[subject] 1025 - 5576 (5582)
(6 hsp)		 0.0 3536   46% Polyketide synthase type I becA Streptomyces sp. DSM 21069
47
 D7P611_CHOCO
(D7P611)		 
[query] 514 - 5066 (5532)
[subject] 985 - 5462 (6255)
(10 hsp)		 0.0 3501   47% TugA tugA Chondromyces crocatus
48
 D9VBL5_9ACTO
(D9VBL5)		 
[query] 38 - 4325 (5532)
[subject] 982 - 4974 (5113)
(8 hsp)		 0.0 3493   50% Modular polyketide synthase SSMG_01148 Streptomyces sp. AA4
49
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 6 - 5066 (5532)
[subject] 5 - 4499 (6260)
(10 hsp)		 0.0 3472   45% Polyketide synthase rapC Streptomyces hygroscopicus
50
 F8JVX1_STRCT
(F8JVX1)		 
[query] 36 - 4571 (5532)
[subject] 1041 - 5405 (6125)
(9 hsp)		 0.0 3469   47% Putative 6-methylsalicylic acid synthase SCAT_0136 Streptomyces cattleya 2.3.1.165

2.3.1.94
51
 C6K7D8_9ACTO
(C6K7D8)		 
[query] 35 - 5434 (5532)
[subject] 3147 - 7858 (7938)
(9 hsp)		 0.0 3453   44% Polyketide synthase rapA Actinoplanes sp. N902-109
52
 Q2PC52_STRAH
(Q2PC52)		 Jump to Rubra_00380 
[query] 1 - 4889 (5532)
[subject] 1 - 4612 (5066)
(5 hsp)		 0.0 3302   45% Putative polyketide synthase rubB Streptomyces achromogenes subsp. rubradiris
53
 C0Z477_STRVN
(C0Z477)		 
[query] 32 - 4569 (5532)
[subject] 1055 - 5375 (6130)
(10 hsp)		 0.0 3299   48% Type I polyketide synthase, loading module and modules 1-3 ken16 Streptomyces violaceoruber
54
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 1 - 4573 (5532)
[subject] 1 - 4265 (8301)
(5 hsp)		 0.0 3285   49% Type I polyketide synthase sfaH Streptomyces flaveolus
55
 E9KTB5_STRKN
(E9KTB5)		 
[query] 35 - 4864 (5532)
[subject] 2778 - 7145 (7591)
(8 hsp)		 0.0 3255   46% Polyketide synthase fkbB
Tcs_SK_031		 Streptomyces kanamyceticus
56
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 815 - 5438 (5532)
[subject] 1628 - 5974 (6078)
(7 hsp)		 0.0 3248   47% ObsA Saccharopolyspora spinosa
57
 Q52V50_9ACTO
(Q52V50)		 
[query] 1484 - 5529 (5532)
[subject] 3549 - 7509 (7510)
(6 hsp)		 0.0 3229   49% Polyketide synthase type I Streptomyces aizunensis
58
 Q52V53_9ACTO
(Q52V53)		 
[query] 1363 - 5529 (5532)
[subject] 1119 - 5206 (5207)
(6 hsp)		 0.0 3196   48% Polyketide synthase type I Streptomyces aizunensis
59
 Q93H87_STRAW
(Q93H87)		 
[query] 1363 - 5529 (5532)
[subject] 2078 - 6047 (6048)
(10 hsp)		 0.0 3183   48% Modular polyketide synthase pteA1 Streptomyces avermitilis
60
 Q9ZGA4_9ACTO
(Q9ZGA4)		 
[query] 35 - 4864 (5532)
[subject] 2780 - 7136 (7576)
(11 hsp)		 0.0 3181   45% FK506 polyketide synthase fkbB Streptomyces sp. MA6548
61
 Q0R4M5_STRAT
(Q0R4M5)		 Jump to Chth_00290 
[query] 1488 - 5438 (5532)
[subject] 1757 - 5630 (5718)
(6 hsp)		 0.0 3117   48% ChlA3 Streptomyces antibioticus
62
 B4VB11_9ACTO
(B4VB11)		 
[query] 1547 - 5507 (5532)
[subject] 5 - 3895 (3928)
(3 hsp)		 0.0 3089   49% Polyketide synthase type I SSAG_04921 Streptomyces sp. Mg1
63
 Q76KY0_STRHA
(Q76KY0)		 Jump to Vicen_00200 
[query] 1518 - 5527 (5532)
[subject] 1871 - 5823 (5826)
(6 hsp)		 0.0 3066   48% Polyketide synthase modules 1-3 vinP1 Streptomyces halstedii
64
 Q0PD02_STRHA
(Q0PD02)		 Jump to Halsto_00030 
[query] 1342 - 5529 (5532)
[subject] 1087 - 5218 (5220)
(6 hsp)		 0.0 3055   47% Type I polyketide synthase hlsC Streptomyces halstedii
65
 D7F1M1_9ACTO
(D7F1M1)		 
[query] 1488 - 5529 (5532)
[subject] 1719 - 5630 (5630)
(6 hsp)		 0.0 3029   46% Polyketide synthase tsnAIII Streptomyces longisporoflavus
66
 Q30CS1_STRAU
(Q30CS1)		 Jump to Alip_00140 
[query] 6 - 3641 (5532)
[subject] 5 - 3503 (3582)
(3 hsp)		 0.0 3018   51% LipPks2 lipPks2 Streptomyces aureofaciens
67
 Q30CS0_STRAU
(Q30CS0)		 Jump to Alip_00150 
[query] 3 - 3666 (5532)
[subject] 2 - 3561 (3612)
(3 hsp)		 0.0 3008   49% LipPks3 lipPks3 Streptomyces aureofaciens
68
 Q82QT5_STRAW
(Q82QT5)		 
[query] 1864 - 5529 (5532)
[subject] 34 - 3563 (3564)
(3 hsp)		 0.0 3006   50% Modular polyketide synthase pteA2
SAV418
SAV_418		 Streptomyces avermitilis
69
 Q93H86_STRAW
(Q93H86)		 
[query] 1871 - 5529 (5532)
[subject] 1 - 3523 (3524)
(3 hsp)		 0.0 2993   50% Modular polyketide synthase pteA2 Streptomyces avermitilis
70
 Q0R4M8_STRAT
(Q0R4M8)		 Jump to Chth_00260 
[query] 8 - 3637 (5532)
[subject] 1059 - 4606 (4699)
(6 hsp)		 0.0 2983   51% ChlA1 Streptomyces antibioticus
71
 E0D206_9ACTO
(E0D206)		 Jump to FD891_00050 
[query] 3 - 3648 (5532)
[subject] 2 - 3501 (3799)
(3 hsp)		 0.0 2974   50% Polyketide synthase gfsE Streptomyces graminofaciens
72
 B6ZIR2_STRPT
(B6ZIR2)		 Jump to Pladi_00010 
[query] 1363 - 5069 (5532)
[subject] 2087 - 5752 (6532)
(14 hsp)		 0.0 2969   49% Polyketide synthase pldAI Streptomyces platensis
73
 E0D205_9ACTO
(E0D205)		 Jump to FD891_00040 
[query] 1854 - 5528 (5532)
[subject] 24 - 3637 (3639)
(2 hsp)		 0.0 2938   48% Polyketide synthase gfsD Streptomyces graminofaciens
74
 D6B4Q9_9ACTO
(D6B4Q9)		 
[query] 1360 - 5440 (5532)
[subject] 112 - 4010 (5945)
(7 hsp)		 0.0 2933   48% Polyketide synthase SSHG_00090 Streptomyces albus J1074
75
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 1864 - 5445 (5532)
[subject] 34 - 3585 (5214)
(9 hsp)		 0.0 2920   49% Polyketide synthase idmN Streptomyces antibioticus
76
 C3VLW9_9ACTO
(C3VLW9)		 
[query] 2 - 3641 (5532)
[subject] 4 - 3294 (3377)
(2 hsp)		 0.0 2915   50% Polyketide synthase type I becF Streptomyces sp. DSM 21069
77
 Q52V49_9ACTO
(Q52V49)		 
[query] 10 - 3643 (5532)
[subject] 4 - 3579 (3872)
(3 hsp)		 0.0 2910   49% Polyketide synthase type I Streptomyces aizunensis
78
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 1482 - 5467 (5532)
[subject] 3394 - 7225 (7488)
(5 hsp)		 0.0 2902   47% ObsC Saccharopolyspora spinosa
79
 C3VLZ7_9ACTO
(C3VLZ7)		 
[query] 2 - 3644 (5532)
[subject] 4 - 3294 (3373)
(2 hsp)		 0.0 2899   49% Polyketide synthase type I mlaF Streptomyces sp. MP39-85
80
 E8WEN9_STRFA
(E8WEN9)		 
[query] 1 - 3643 (5532)
[subject] 1 - 3422 (3511)
(4 hsp)		 0.0 2898   49% Mycocerosate synthase, 6-deoxyerythronolide-B synthase Sfla_0983 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD) 2.3.1.111

2.3.1.94
81
 D7C2B8_STRBB
(D7C2B8)		 
[query] 1483 - 5073 (5532)
[subject] 3260 - 6731 (7498)
(13 hsp)		 0.0 2893   49% Type I modular polyketide synthase pks3-2
SBI_00651		 Streptomyces bingchenggensis (strain BCW-1)
82
 Q1MX73_9ACTO
(Q1MX73)		 Jump to Tetrn_00160 
[query] 1488 - 5503 (5532)
[subject] 1736 - 5622 (5657)
(5 hsp)		 0.0 2891   46% Type I polyketide synthase tmnAIV Streptomyces sp. NRRL 11266
83
 Q8CJN6_STRCO
(Q8CJN6)		 
[query] 1771 - 5524 (5532)
[subject] 925 - 4554 (4557)
(6 hsp)		 0.0 2873   47% Putative type I polyketide synthase SCO6275 Streptomyces coelicolor
84
 D6EJM4_STRLI
(D6EJM4)		 
[query] 1771 - 5524 (5532)
[subject] 969 - 4596 (4599)
(6 hsp)		 0.0 2862   47% Type I polyketide synthase SSPG_01356 Streptomyces lividans TK24
85
 F8QPG1_9ACTO
(F8QPG1)		 
[query] 12 - 3652 (5532)
[subject] 7 - 3548 (3621)
(4 hsp)		 0.0 2835   49% Polyketide synthase natD Streptomyces sp. CS
86
 Q9EX53_STRCO
(Q9EX53)		 
[query] 1864 - 5528 (5532)
[subject] 34 - 3572 (3576)
(3 hsp)		 0.0 2825   48% Putative type I polyketide synthase SCO6274 Streptomyces coelicolor
87
 C5HV15_STRAT
(C5HV15)		 Jump to Indano_00170 
[query] 1864 - 5528 (5532)
[subject] 36 - 3590 (3596)
(4 hsp)		 0.0 2819   47% Polyketide synthase idmM Streptomyces antibioticus
88
 C3VLV8_9ACTO
(C3VLV8)		 
[query] 1762 - 5452 (5532)
[subject] 3 - 3498 (3527)
(4 hsp)		 0.0 2818   47% Polyketide synthase type I becB Streptomyces sp. DSM 21069
89
 D7F1N2_9ACTO
(D7F1N2)		 
[query] 1755 - 5148 (5532)
[subject] 981 - 4318 (5029)
(9 hsp)		 0.0 2817   50% Polyketide synthase tsnAI Streptomyces longisporoflavus
90
 A8LUX2_SALAI
(A8LUX2)		 
[query] 1768 - 5434 (5532)
[subject] 905 - 4363 (7279)
(14 hsp)		 0.0 2803   48% Beta-ketoacyl synthase Sare_3156 Salinispora arenicola (strain CNS-205)
91
 C3VLY6_9ACTO
(C3VLY6)		 
[query] 1762 - 5438 (5532)
[subject] 3 - 3483 (3530)
(3 hsp)		 0.0 2801   47% Polyketide synthase type I mlaB Streptomyces sp. MP39-85
92
 Q9S0R8_STRAW
(Q9S0R8)		 Jump to Aver_00040 
[query] 1514 - 3642 (5532)
[subject] 1741 - 3891 (3972)
(10 hsp)		 0.0 2800   77% Type I polyketide synthase AVES 1 aveA1
SAV938
SAV_938		 Streptomyces avermitilis
93
 A8M6D0_SALAI
(A8M6D0)		 
[query] 1863 - 5438 (5532)
[subject] 30 - 3481 (3494)
(4 hsp)		 0.0 2800   49% Acyl transferase Sare_1250 Salinispora arenicola (strain CNS-205)
94
 Q0QMQ0_9ACTO
(Q0QMQ0)		 
[query] 1864 - 5513 (5532)
[subject] 35 - 3529 (3554)
(4 hsp)		 0.0 2800   49% Polyketide synthase type I Streptomyces aculeolatus
95
 Q68BG4_STRHA
(Q68BG4)		 Jump to Halsto_00020 
[query] 1342 - 5066 (5532)
[subject] 1084 - 4732 (7111)
(13 hsp)		 0.0 2792   47% Type I polyketide synthase hlsB Streptomyces halstedii
96
 B4ER95_STRON
(B4ER95)		 
[query] 3 - 3641 (5532)
[subject] 2 - 3537 (3625)
(3 hsp)		 0.0 2788   48% Protein modular polyketide synthase NorA' norA' Streptoverticillium orinoci
97
 F8JKR1_STRCT
(F8JKR1)		 
[query] 33 - 3647 (5532)
[subject] 1039 - 4418 (4492)
(5 hsp)		 0.0 2777   49% Putative Beta-ketoacyl-acyl-carrier-protein synthase II SCAT_p1475 Streptomyces cattleya NRRL 8057 2.3.1.179
98
 Q76KZ3_STRHA
(Q76KZ3)		 Jump to Vicen_00070 
[query] 3 - 3637 (5532)
[subject] 2 - 3496 (3808)
(4 hsp)		 0.0 2776   48% Polyketide synthase modules 7-8 vinP4 Streptomyces halstedii
99
 D8HZ86_AMYMU
(D8HZ86)		 
[query] 1863 - 5441 (5532)
[subject] 30 - 3412 (3413)
(3 hsp)		 0.0 2771   48% Rifamycin polyketide synthase rifE
AMED_0621		 Amycolatopsis mediterranei (strain U-32)
100
 O54593_AMYMD
(O54593)		 Jump to Rifam_00250 
[query] 1863 - 5441 (5532)
[subject] 30 - 3412 (3413)
(3 hsp)		 0.0 2771   48% RifE
Rifamycin polyketide synthase, type 1		 rifE Amycolatopsis mediterranei
Nocardia mediterranei
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 Q9S0R4_STRAW
(Q9S0R4)		 
[query] 1 - 5532 (5532)
[subject] 1 - 5532 (5532)
 0.0 10930   100%
Product
Type I polyketide synthase AVES 3
Gene
aveA3
SAV942
SAV_942
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 10449723 [Medline] 99380548
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999]
2uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
3uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
4
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 36 - 5529 (5532)
[subject] 1020 - 6240 (6241)
(5 hsp)		 0.0 4373   50%
Product
Polyketide synthase
Gene
KijS1
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
5
 Q82QT4_STRAW
(Q82QT4)		 
[query] 38 - 5529 (5532)
[subject] 2552 - 7745 (7746)
(10 hsp)		 0.0 4332   49%
Product
Modular polyketide synthase
Gene
pteA1
SAV419
SAV_419
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
7
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 4 - 5438 (5532)
[subject] 3 - 5290 (5588)
(4 hsp)		 0.0 4286   48%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
9
 Q52V52_9ACTO
(Q52V52)		 
[query] 3 - 5528 (5532)
[subject] 2 - 5430 (5432)
 0.0 4251   48%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
10
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 1 - 5529 (5532)
[subject] 1 - 5338 (5339)
 0.0 4236   48%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
13
 B5L6K8_MICCH
(B5L6K8)		 
[query] 39 - 5528 (5532)
[subject] 1023 - 6303 (6305)
(6 hsp)		 0.0 4205   48%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
14
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 31 - 5529 (5532)
[subject] 1571 - 6830 (6831)
(6 hsp)		 0.0 4179   48%
Product
ScnS1
Gene
scnS1
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
15
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 28 - 5527 (5532)
[subject] 1872 - 7106 (7110)
(4 hsp)		 0.0 4177   49%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2695
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
16
 D7BRD4_STRBB
(D7BRD4)		 
[query] 44 - 5529 (5532)
[subject] 4604 - 9949 (9950)
(7 hsp)		 0.0 4164   48%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_01976
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
17
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 38 - 5529 (5532)
[subject] 5575 - 10916 (10917)
(7 hsp)		 0.0 4130   47%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
18
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 31 - 5529 (5532)
[subject] 1555 - 6796 (6797)
(6 hsp)		 0.0 4116   48%
Product
PimS1 protein
Polyketide synthase
Gene
pimS1
Organism
Streptomyces natalensis
1uniprot[Pubmed] 10187796 [Medline] 99214571
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999]
2uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
[pubmed all]
19
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 4 - 5529 (5532)
[subject] 3 - 5098 (5099)
 0.0 4099   47%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
20
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 1 - 5442 (5532)
[subject] 1 - 5009 (5060)
(2 hsp)		 0.0 4065   48%
Product
Rifamycin polyketide synthase
Gene
rifB
AMED_0618
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
22
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 1 - 5442 (5532)
[subject] 1 - 5009 (5060)
(2 hsp)		 0.0 4063   48%
Product
RifB
Gene
rifB
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
23
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 35 - 5528 (5532)
[subject] 28 - 5320 (5321)
 0.0 4041   48%
Product
Polyketide synthase
Gene
natC
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
24
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 36 - 5529 (5532)
[subject] 1024 - 6382 (6383)
(7 hsp)		 0.0 4018   45%
Product
Polyketide synthase type I
Gene
mlaA1
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
26
 D6C477_9ACTO
(D6C477)		 Jump to Meili_00310 
[query] 1488 - 5527 (5532)
[subject] 1789 - 5819 (5822)
(6 hsp)		 0.0 3989   57%
Product
Modular polyketide synthase
Gene
meiA3
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
27
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 36 - 5441 (5532)
[subject] 1786 - 6948 (10625)
(7 hsp)		 0.0 3982   48%
Product
FscC
Gene
fscC
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
28
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 31 - 5504 (5532)
[subject] 5577 - 10837 (10876)
(5 hsp)		 0.0 3972   48%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
29
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 35 - 5528 (5532)
[subject] 5251 - 10219 (10223)
(4 hsp)		 0.0 3968   46%
Product
Polyketide synthase
Gene
rapB
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
30
 B5L6K9_MICCH
(B5L6K9)		 
[query] 31 - 5439 (5532)
[subject] 1732 - 6934 (7007)
(3 hsp)		 0.0 3957   47%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
31
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 1 - 5526 (5532)
[subject] 1 - 5176 (5176)
 0.0 3900   46%
Product
ObsB
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
32
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 4 - 5438 (5532)
[subject] 8 - 5110 (5400)
(2 hsp)		 0.0 3852   47%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2684
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
33
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 31 - 5081 (5532)
[subject] 3795 - 8586 (10827)
(17 hsp)		 0.0 3818   49%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
34
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 1 - 5069 (5532)
[subject] 1 - 4914 (11096)
(10 hsp)		 0.0 3817   48%
Product
NysC
Gene
nysC
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
40
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 2 - 4569 (5532)
[subject] 5 - 4557 (7026)
(6 hsp)		 0.0 3680   49%
Product
Polyketide synthase
Gene
pldAII
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
41
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 36 - 5067 (5532)
[subject] 4139 - 8783 (9528)
(12 hsp)		 0.0 3675   47%
Product
Type I modular polyketide synthase
Gene
ttnA
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
42
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 36 - 5067 (5532)
[subject] 4255 - 8903 (9648)
(11 hsp)		 0.0 3665   47%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
43
 B3TMQ7_9ACTO
(B3TMQ7)		 
[query] 5 - 5268 (5532)
[subject] 2 - 4958 (6872)
(5 hsp)		 0.0 3634   46%
Product
Polyketide synthase
Gene
KijS2
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
45
 B1W5P4_STRGG
(B1W5P4)		 
[query] 3 - 5524 (5532)
[subject] 2 - 4838 (4843)
 0.0 3547   44%
Product
Putative type-I PKS
Gene
pks3-2
SGR_6372
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
46
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 36 - 4701 (5532)
[subject] 1025 - 5576 (5582)
(6 hsp)		 0.0 3536   46%
Product
Polyketide synthase type I
Gene
becA
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
47
 D7P611_CHOCO
(D7P611)		 
[query] 514 - 5066 (5532)
[subject] 985 - 5462 (6255)
(10 hsp)		 0.0 3501   47%
Product
TugA
Gene
tugA
Organism
Chondromyces crocatus
1uniprot[Pubmed] 20416506
Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010]
49
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 6 - 5066 (5532)
[subject] 5 - 4499 (6260)
(10 hsp)		 0.0 3472   45%
Product
Polyketide synthase
Gene
rapC
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
52
 Q2PC52_STRAH
(Q2PC52)		 Jump to Rubra_00380 
[query] 1 - 4889 (5532)
[subject] 1 - 4612 (5066)
(5 hsp)		 0.0 3302   45%
Product
Putative polyketide synthase
Gene
rubB
Organism
Streptomyces achromogenes subsp. rubradiris
1uniprot[Pubmed] 9387157 [Medline] 98048398
Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997]
2uniprot[Pubmed] 12889805 [Medline] 22771458
Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003]
[pubmed all]
54
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 1 - 4573 (5532)
[subject] 1 - 4265 (8301)
(5 hsp)		 0.0 3285   49%
Product
Type I polyketide synthase
Gene
sfaH
Organism
Streptomyces flaveolus
1uniprot
Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010]
55
 E9KTB5_STRKN
(E9KTB5)		 
[query] 35 - 4864 (5532)
[subject] 2778 - 7145 (7591)
(8 hsp)		 0.0 3255   46%
Product
Polyketide synthase
Gene
fkbB
Tcs_SK_031
Organism
Streptomyces kanamyceticus
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
56
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 815 - 5438 (5532)
[subject] 1628 - 5974 (6078)
(7 hsp)		 0.0 3248   47%
Product
ObsA
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
57
 Q52V50_9ACTO
(Q52V50)		 
[query] 1484 - 5529 (5532)
[subject] 3549 - 7509 (7510)
(6 hsp)		 0.0 3229   49%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
58
 Q52V53_9ACTO
(Q52V53)		 
[query] 1363 - 5529 (5532)
[subject] 1119 - 5206 (5207)
(6 hsp)		 0.0 3196   48%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
59
 Q93H87_STRAW
(Q93H87)		 
[query] 1363 - 5529 (5532)
[subject] 2078 - 6047 (6048)
(10 hsp)		 0.0 3183   48%
Product
Modular polyketide synthase
Gene
pteA1
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
60
 Q9ZGA4_9ACTO
(Q9ZGA4)		 
[query] 35 - 4864 (5532)
[subject] 2780 - 7136 (7576)
(11 hsp)		 0.0 3181   45%
Product
FK506 polyketide synthase
Gene
fkbB
Organism
Streptomyces sp. MA6548
1uniprot[Pubmed] 9780228 [Medline] 98451508
The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506.(Eur. J. Biochem.) [1998]
61
 Q0R4M5_STRAT
(Q0R4M5)		 Jump to Chth_00290 
[query] 1488 - 5438 (5532)
[subject] 1757 - 5630 (5718)
(6 hsp)		 0.0 3117   48%
Product
ChlA3
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
63
 Q76KY0_STRHA
(Q76KY0)		 Jump to Vicen_00200 
[query] 1518 - 5527 (5532)
[subject] 1871 - 5823 (5826)
(6 hsp)		 0.0 3066   48%
Product
Polyketide synthase modules 1-3
Gene
vinP1
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
66
 Q30CS1_STRAU
(Q30CS1)		 Jump to Alip_00140 
[query] 6 - 3641 (5532)
[subject] 5 - 3503 (3582)
(3 hsp)		 0.0 3018   51%
Product
LipPks2
Gene
lipPks2
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 16723573
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006]
67
 Q30CS0_STRAU
(Q30CS0)		 Jump to Alip_00150 
[query] 3 - 3666 (5532)
[subject] 2 - 3561 (3612)
(3 hsp)		 0.0 3008   49%
Product
LipPks3
Gene
lipPks3
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 16723573
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006]
68
 Q82QT5_STRAW
(Q82QT5)		 
[query] 1864 - 5529 (5532)
[subject] 34 - 3563 (3564)
(3 hsp)		 0.0 3006   50%
Product
Modular polyketide synthase
Gene
pteA2
SAV418
SAV_418
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
69
 Q93H86_STRAW
(Q93H86)		 
[query] 1871 - 5529 (5532)
[subject] 1 - 3523 (3524)
(3 hsp)		 0.0 2993   50%
Product
Modular polyketide synthase
Gene
pteA2
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
70
 Q0R4M8_STRAT
(Q0R4M8)		 Jump to Chth_00260 
[query] 8 - 3637 (5532)
[subject] 1059 - 4606 (4699)
(6 hsp)		 0.0 2983   51%
Product
ChlA1
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
71
 E0D206_9ACTO
(E0D206)		 Jump to FD891_00050 
[query] 3 - 3648 (5532)
[subject] 2 - 3501 (3799)
(3 hsp)		 0.0 2974   50%
Product
Polyketide synthase
Gene
gfsE
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
72
 B6ZIR2_STRPT
(B6ZIR2)		 Jump to Pladi_00010 
[query] 1363 - 5069 (5532)
[subject] 2087 - 5752 (6532)
(14 hsp)		 0.0 2969   49%
Product
Polyketide synthase
Gene
pldAI
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
73
 E0D205_9ACTO
(E0D205)		 Jump to FD891_00040 
[query] 1854 - 5528 (5532)
[subject] 24 - 3637 (3639)
(2 hsp)		 0.0 2938   48%
Product
Polyketide synthase
Gene
gfsD
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
75
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 1864 - 5445 (5532)
[subject] 34 - 3585 (5214)
(9 hsp)		 0.0 2920   49%
Product
Polyketide synthase
Gene
idmN
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
76
 C3VLW9_9ACTO
(C3VLW9)		 
[query] 2 - 3641 (5532)
[subject] 4 - 3294 (3377)
(2 hsp)		 0.0 2915   50%
Product
Polyketide synthase type I
Gene
becF
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
77
 Q52V49_9ACTO
(Q52V49)		 
[query] 10 - 3643 (5532)
[subject] 4 - 3579 (3872)
(3 hsp)		 0.0 2910   49%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
78
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 1482 - 5467 (5532)
[subject] 3394 - 7225 (7488)
(5 hsp)		 0.0 2902   47%
Product
ObsC
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
79
 C3VLZ7_9ACTO
(C3VLZ7)		 
[query] 2 - 3644 (5532)
[subject] 4 - 3294 (3373)
(2 hsp)		 0.0 2899   49%
Product
Polyketide synthase type I
Gene
mlaF
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
81
 D7C2B8_STRBB
(D7C2B8)		 
[query] 1483 - 5073 (5532)
[subject] 3260 - 6731 (7498)
(13 hsp)		 0.0 2893   49%
Product
Type I modular polyketide synthase
Gene
pks3-2
SBI_00651
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
83
 Q8CJN6_STRCO
(Q8CJN6)		 
[query] 1771 - 5524 (5532)
[subject] 925 - 4554 (4557)
(6 hsp)		 0.0 2873   47%
Product
Putative type I polyketide synthase
Gene
SCO6275
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
85
 F8QPG1_9ACTO
(F8QPG1)		 
[query] 12 - 3652 (5532)
[subject] 7 - 3548 (3621)
(4 hsp)		 0.0 2835   49%
Product
Polyketide synthase
Gene
natD
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
86
 Q9EX53_STRCO
(Q9EX53)		 
[query] 1864 - 5528 (5532)
[subject] 34 - 3572 (3576)
(3 hsp)		 0.0 2825   48%
Product
Putative type I polyketide synthase
Gene
SCO6274
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
87
 C5HV15_STRAT
(C5HV15)		 Jump to Indano_00170 
[query] 1864 - 5528 (5532)
[subject] 36 - 3590 (3596)
(4 hsp)		 0.0 2819   47%
Product
Polyketide synthase
Gene
idmM
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
88
 C3VLV8_9ACTO
(C3VLV8)		 
[query] 1762 - 5452 (5532)
[subject] 3 - 3498 (3527)
(4 hsp)		 0.0 2818   47%
Product
Polyketide synthase type I
Gene
becB
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
91
 C3VLY6_9ACTO
(C3VLY6)		 
[query] 1762 - 5438 (5532)
[subject] 3 - 3483 (3530)
(3 hsp)		 0.0 2801   47%
Product
Polyketide synthase type I
Gene
mlaB
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
92
 Q9S0R8_STRAW
(Q9S0R8)		 Jump to Aver_00040 
[query] 1514 - 3642 (5532)
[subject] 1741 - 3891 (3972)
(10 hsp)		 0.0 2800   77%
Product
Type I polyketide synthase AVES 1
Gene
aveA1
SAV938
SAV_938
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 10449723 [Medline] 99380548
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999]
2uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
3uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
94
 Q0QMQ0_9ACTO
(Q0QMQ0)		 
[query] 1864 - 5513 (5532)
[subject] 35 - 3529 (3554)
(4 hsp)		 0.0 2800   49%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aculeolatus
1uniprot[Pubmed] 16724457
Isolation and identification of three new 5-alkenyl-3,3(2H)-furanones from two streptomyces species using a genomic screening approach.(J. Antibiot.) [2006]
95
 Q68BG4_STRHA
(Q68BG4)		 Jump to Halsto_00020 
[query] 1342 - 5066 (5532)
[subject] 1084 - 4732 (7111)
(13 hsp)		 0.0 2792   47%
Product
Type I polyketide synthase
Gene
hlsB
Organism
Streptomyces halstedii
1uniprot
Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004]
98
 Q76KZ3_STRHA
(Q76KZ3)		 Jump to Vicen_00070 
[query] 3 - 3637 (5532)
[subject] 2 - 3496 (3808)
(4 hsp)		 0.0 2776   48%
Product
Polyketide synthase modules 7-8
Gene
vinP4
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
99
 D8HZ86_AMYMU
(D8HZ86)		 
[query] 1863 - 5441 (5532)
[subject] 30 - 3412 (3413)
(3 hsp)		 0.0 2771   48%
Product
Rifamycin polyketide synthase
Gene
rifE
AMED_0621
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
100
 O54593_AMYMD
(O54593)		 Jump to Rifam_00250 
[query] 1863 - 5441 (5532)
[subject] 30 - 3412 (3413)
(3 hsp)		 0.0 2771   48%
Product
RifE
Rifamycin polyketide synthase, type 1
Gene
rifE
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]