| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
Q70DW8_9ACTO (Q70DW8) |
|
|
1e-82 |
308 |
100% |
|
- Product
- RemI protein
- Gene
- remI
- Organism
- Streptomyces resistomycificus
|
1uniprot[Pubmed] 14982421 A gene cluster encoding resistomycin biosynthesis in Streptomyces resistomycificus; exploring polyketide cyclization beyond linear and angucyclic patterns.(J. Am. Chem. Soc.) [2004] |
|
4
|
F4F9S5_VERMA (F4F9S5) |
|
|
3e-18 |
95.1 |
42% |
|
- Product
- Cyclase/dehydrase
- Gene
- VAB18032_23765
- Organism
- Verrucosispora maris (strain AB-18-032)
|
1uniprot[Pubmed] 21551311 Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011] |
|
5
|
A8KQY4_9ACTO (A8KQY4) |
|
|
1e-17 |
93.6 |
39% |
|
- Product
- Aromatase
- Gene
- elmNI
- Organism
- Streptomyces olivaceus
|
1uniprot[Pubmed] 18310024 Biosynthesis of elloramycin in Streptomyces olivaceus requires glycosylation by enzymes encoded outside the aglycon cluster.(Microbiology) [2008] |
|
6
|
TCMN_STRGA (P16559) |
|
|
3e-17 |
91.7 |
39% |
|
- Product
- Multifunctional cyclase-dehydratase-3-O-methyl transferase tcmN
- Gene
- tcmN
- Organism
- Streptomyces glaucescens
|
1uniprot[Pubmed] 1548230 [Medline] 92193265 Nucleotide sequence of the tcmII-tcmIV region of the tetracenomycin C biosynthetic gene cluster of Streptomyces glaucescens and evidence that the tcmN gene encodes a multifunctional cyclase-dehydratase-O-methyl transferase.(J. Bacteriol.) [1992] | 2uniprot[Pubmed] 2684656 [Medline] 90060035 Analysis of the nucleotide sequence of the Streptomyces glaucescens tcmI genes provides key information about the enzymology of polyketide antibiotic biosynthesis.(EMBO J.) [1989] | [pubmed all]
|
7
|
C9Z708_STRSW (C9Z708) |
|
|
4e-17 |
91.7 |
38% |
|
- Product
- Putative polyketide cyclase
- Gene
- sppD
SCAB_43331
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
8
|
O32454_9ACTO (O32454) |
|
|
1e-16 |
89.7 |
40% |
|
- Product
- ORF 4
PdmD
- Gene
- pdmD
- Organism
- Actinomadura hibisca
|
1uniprot[Pubmed] 9339544 [Medline] 97480928 Cloning and nucleotide sequence of the putative polyketide synthase genes for pradimicin biosynthesis from Actinomadura hibisca.(Biosci. Biotechnol. Biochem.) [1997] |
|
11
|
CYPC_STRCN (Q02572) |
|
|
6e-16 |
87.8 |
39% |
|
- Product
- Putative polyketide cyclase
- Gene
- curF
- Organism
- Streptomyces cyaneus
Streptomyces curacoi
|
1uniprot[Pubmed] 1644304 [Medline] 92354925 Analysis of a polyketide synthesis-encoding gene cluster of Streptomyces curacoi.(Gene) [1992] |
|
12
|
F2RIV3_STRVP (F2RIV3) |
|
|
8e-16 |
87 |
36% |
|
- Product
- Aromatase WhiE VI
- Gene
- SVEN_6793
- Organism
- Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
|
1uniprot[Pubmed] 21463507 Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011] |
|
14
|
F3NHY0_9ACTO (F3NHY0) |
|
|
1e-15 |
86.7 |
36% |
|
- Product
- Polyketide cyclase
- Gene
- SGM_2744
- Organism
- Streptomyces griseoaurantiacus M045
|
1uniprot[Pubmed] 21551298 Draft Genome Sequence of the Marine Bacterium Streptomyces griseoaurantiacus M045, Which Produces Novel Manumycin-Type Antibiotics with a pABA Core Component.(J. Bacteriol.) [2011] |
|
15
|
B1GSN4_9ACTO (B1GSN4) |
|
|
1e-15 |
86.7 |
37% |
|
- Product
- BenH protein
- Gene
- benH
- Organism
- Streptomyces sp. A2991200
|
1uniprot[Pubmed] 17439117 Molecular analysis of the benastatin biosynthetic pathway and genetic engineering of altered fatty acid-polyketide hybrids.(J. Am. Chem. Soc.) [2007] |
|
16
|
C7Q5R8_CATAD (C7Q5R8) |
|
|
1e-15 |
86.3 |
37% |
|
- Product
- Cyclase/dehydrase
- Gene
- Caci_1089
- Organism
- Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
|
1uniprot Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009] |
|
21
|
Q93HL9_STRAW (Q93HL9) |
|
|
5e-15 |
84.7 |
38% |
|
- Product
- Cyclase I
Putative cyclase I
- Gene
- sppD
SAV2841 SAV_2841
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
23
|
D7C2K5_STRBB (D7C2K5) |
|
|
6e-15 |
84.3 |
35% |
|
- Product
- Putative polyketide cyclase I
- Gene
- sppD
SBI_02767
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
24
|
A7DWI6_STRTE (A7DWI6) |
|
|
8e-15 |
84 |
40% |
|
- Product
- Putative polyketide cyclase
- Gene
- llpCI
- Organism
- Streptomyces tendae
|
1uniprot Isolation of the lysolipin gene cluster of Streptomyces tendae Tu 4042.(Gene) [2010] |
|
26
|
E4NJ54_KITSK (E4NJ54) |
|
|
1e-14 |
83.6 |
34% |
|
- Product
- Putative cyclase I
- Gene
- sppD
KSE_72470
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
30
|
C7N0D4_SACVD (C7N0D4) |
|
|
3e-14 |
82 |
38% |
|
- Product
- Polyketide cyclase / dehydrase family protein
- Gene
- Svir_33720
- Organism
- Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
|
1uniprot Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009] |
|
33
|
CYPC_STRCO (P23154) |
|
|
8e-14 |
80.5 |
34% |
|
- Product
- Putative polyketide cyclase
WhiE ORF VI
- Gene
- SCO5315
SC6G9.18
- Organism
- Streptomyces coelicolor
|
1uniprot[Pubmed] 2077356 [Medline] 91171868 Spore colour in Streptomyces coelicolor A3(2) involves the developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics.(Mol. Microbiol.) [1990] | 2uniprot[Pubmed] 12000953 [Medline] 21996410 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002] | [pubmed all]
|
34
|
D8I4L8_AMYMU (D8I4L8) |
|
|
1e-13 |
79.7 |
38% |
|
- Product
- Polyketide cyclase/dehydratase
- Gene
- actV
AMED_5432
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
36
|
A8L2X6_FRASN (A8L2X6) |
|
|
2e-13 |
79.3 |
33% |
|
- Product
- Cyclase/dehydrase
- Gene
- Franean1_2391
- Organism
- Frankia sp. (strain EAN1pec)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
37
|
F4FBR6_VERMA (F4FBR6) |
|
|
2e-13 |
79.3 |
38% |
|
- Product
- Putative uncharacterized protein
- Gene
- VAB18032_18070
- Organism
- Verrucosispora maris (strain AB-18-032)
|
1uniprot[Pubmed] 21551311 Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011] |
|
38
|
Q2MGC8_STRGR (Q2MGC8) |
|
|
2e-13 |
79.3 |
37% |
|
- Product
- Putative polyketide cyclase
- Gene
-
- Organism
- Streptomyces griseus
|
1uniprot[Pubmed] 16305230 Cloning, sequencing, analysis, and heterologous expression of the fredericamycin biosynthetic gene cluster from Streptomyces griseus.(J. Am. Chem. Soc.) [2005] |
|
40
|
Q8KSW2_9ACTO (Q8KSW2) |
|
|
3e-13 |
78.6 |
36% |
|
- Product
- Putative bifunctional cyclase/3-oxoacyl-ACP reductase GrhT
- Gene
- grhT
- Organism
- Streptomyces sp. JP95
|
1uniprot[Pubmed] 12323376 [Medline] 22235582 A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A.(Chem. Biol.) [2002] |
|
46
|
E2PW01_STRCL (E2PW01) |
|
|
3e-12 |
75.5 |
35% |
|
- Product
- Polyketide cyclase
- Gene
- sppD
SCLAV_4918
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
47
|
Q2J931_FRASC (Q2J931) |
|
|
3e-12 |
75.5 |
34% |
|
- Product
- Cyclase/dehydrase
- Gene
- Francci3_2853
- Organism
- Frankia sp. (strain CcI3)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
49
|
D2AY47_STRRD (D2AY47) |
|
|
9e-12 |
73.9 |
37% |
|
- Product
- Putative uncharacterized protein
- Gene
- Sros_4153
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
50
|
B0LJ44_9ACTO (B0LJ44) |
|
|
1e-11 |
73.6 |
35% |
|
- Product
- Lcz27
- Gene
- lcz27
- Organism
- Streptomyces sanglieri
|
1uniprot[Pubmed] 18070976 Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008] |
|
51
|
B0LJ10_9ACTO (B0LJ10) |
|
|
2e-11 |
72.8 |
35% |
|
- Product
- Lct27
- Gene
- lct27
- Organism
- Streptomyces rishiriensis
|
1uniprot[Pubmed] 18070976 Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008] |
|
52
|
E2EKK2_9ACTO (E2EKK2) |
|
|
2e-11 |
72.8 |
36% |
|
- Product
- Polyketide cyclase/aromatase
- Gene
- sanI
- Organism
- Streptomyces sp. SANK 61196
|
1uniprot[Pubmed] 20550125 Cloning, sequencing, heterologous expression, and mechanistic analysis of A-74528 biosynthesis.(J. Am. Chem. Soc.) [2010] |
|
53
|
Q0RHJ5_FRAAA (Q0RHJ5) |
|
|
2e-11 |
72.4 |
35% |
|
- Product
- Putative polyketide cyclase
- Gene
- FRAAL4389
- Organism
- Frankia alni (strain ACN14a)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
55
|
D2SZ02_MICEC (D2SZ02) |
|
|
3e-11 |
72 |
35% |
|
- Product
- Cyclase
- Gene
-
- Organism
- Micromonospora echinospora subsp. challisensis
|
1uniprot[Pubmed] 19680283 TLN-05220, TLN-05223, new Echinosporamicin-type antibiotics, and proposed revision of the structure of bravomicins(*).(J. Antibiot.) [2009] |
|
56
|
CYPC_STRHA (Q05368) |
|
|
6e-11 |
70.9 |
41% |
|
- Product
- Putative polyketide cyclase
- Gene
- sch4
- Organism
- Streptomyces halstedii
|
1uniprot[Pubmed] 8344517 [Medline] 93345807 Hybridization and DNA sequence analyses suggest an early evolutionary divergence of related biosynthetic gene sets encoding polyketide antibiotics and spore pigments in Streptomyces spp.(Gene) [1993] |
|
59
|
D5UC53_CELFN (D5UC53) |
|
|
8e-10 |
67.4 |
34% |
|
- Product
- Cupin 2 conserved barrel domain protein
- Gene
- Cfla_3333
- Organism
- Cellulomonas flavigena (strain ATCC 482 / DSM 20109 / NCIB 8073 / NRS 134)
|
1uniprot Complete genome sequence of Cellulomonas flavigena type strain (134).(Stand. Genomic Sci.) [2010] |
|
62
|
D7AVZ9_NOCDD (D7AVZ9) |
|
|
2e-08 |
62.8 |
34% |
|
- Product
- Polyketide cyclase/dehydrase
- Gene
- Ndas_4270
- Organism
- Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
|
1uniprot Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010] |
|
64
|
Q54999_9ACTO (Q54999) |
|
|
0.0001 |
50.1 |
31% |
|
- Product
- Aromatase
- Gene
- frnQ
- Organism
- Streptomyces roseofulvus
|
1uniprot[Pubmed] 8181754 [Medline] 94237486 Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin.(Gene) [1994] |
|