| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
B0B507_STRCU (B0B507) |
|
|
0.0 |
5600 |
100% |
|
- Product
- Putative polyketide synthase
- Gene
- kirAVI
- Organism
- Streptomyces collinus
|
1uniprot[Pubmed] 18291322 Molecular Analysis of the Kirromycin Biosynthetic Gene Cluster Revealed beta-Alanine as Precursor of the Pyridone Moiety.(Chem. Biol.) [2008] |
|
2
|
E4NIM2_KITSK (E4NIM2) |
|
(4 hsp) |
0.0 |
3420 |
70% |
|
- Product
- Putative modular polyketide synthase
- Gene
- pks1-5
KSE_70620
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
3
|
C3VLZ7_9ACTO (C3VLZ7) |
|
(5 hsp) |
0.0 |
2324 |
52% |
|
- Product
- Polyketide synthase type I
- Gene
- mlaF
- Organism
- Streptomyces sp. MP39-85
|
1uniprot[Pubmed] 19854930 Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010] |
|
4
|
Q0R4M8_STRAT (Q0R4M8) |
|
(8 hsp) |
0.0 |
2317 |
53% |
|
- Product
- ChlA1
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006] |
|
5
|
C3VLW9_9ACTO (C3VLW9) |
|
(4 hsp) |
0.0 |
2310 |
52% |
|
- Product
- Polyketide synthase type I
- Gene
- becF
- Organism
- Streptomyces sp. DSM 21069
|
1uniprot[Pubmed] 19875084 Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009] |
|
7
|
Q30CS1_STRAU (Q30CS1) |
|
(4 hsp) |
0.0 |
2287 |
52% |
|
- Product
- LipPks2
- Gene
- lipPks2
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 16723573 Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006] |
|
8
|
Q9ALM2_9PSEU (Q9ALM2) |
|
(4 hsp) |
0.0 |
2286 |
51% |
|
- Product
- Polyketide synthase extender modules 8-10
- Gene
- spnE
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001] |
|
16
|
C9YYI2_STRSW (C9YYI2) |
|
(6 hsp) |
0.0 |
2261 |
53% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83911
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
17
|
C6WNW1_ACTMD (C6WNW1) |
|
(9 hsp) |
0.0 |
2260 |
53% |
|
- Product
- Short-chain dehydrogenase/reductase SDR
- Gene
- Amir_2695
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
18
|
Q52V49_9ACTO (Q52V49) |
|
(4 hsp) |
0.0 |
2256 |
51% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
20
|
Q6JHN7_9PSEU (Q6JHN7) |
|
(6 hsp) |
0.0 |
2249 |
51% |
|
- Product
- ObsB
- Gene
-
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 15346767 Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004] |
|
23
|
Q3S863_9ACTO (Q3S863) |
|
(5 hsp) |
0.0 |
2244 |
52% |
|
- Product
- Modular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
24
|
Q30CS0_STRAU (Q30CS0) |
|
(3 hsp) |
0.0 |
2241 |
50% |
|
- Product
- LipPks3
- Gene
- lipPks3
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 16723573 Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006] |
|
25
|
Q0S8W4_RHOSR (Q0S8W4) |
|
(4 hsp) |
0.0 |
2237 |
51% |
|
- Product
- Type I polyketide synthase
- Gene
- RHA1_ro04231
- Organism
- Rhodococcus sp. (strain RHA1)
|
1uniprot[Pubmed] 17030794 The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse.(Proc. Natl. Acad. Sci. U.S.A.) [2006] |
|
27
|
F8QPG0_9ACTO (F8QPG0) |
|
(4 hsp) |
0.0 |
2231 |
52% |
|
- Product
- Polyketide synthase
- Gene
- natC
- Organism
- Streptomyces sp. CS
|
1uniprot[Pubmed] 21614382 Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011] |
|
28
|
D3U9Y8_9ACTO (D3U9Y8) |
|
(9 hsp) |
0.0 |
2229 |
53% |
|
- Product
- Type I polyketide synthase
- Gene
- sfaH
- Organism
- Streptomyces flaveolus
|
1uniprot Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010] |
|
30
|
Q9X993_9ACTO (Q9X993) |
|
(8 hsp) |
0.0 |
2224 |
51% |
|
- Product
- PimS1 protein
Polyketide synthase
- Gene
- pimS1
- Organism
- Streptomyces natalensis
|
1uniprot[Pubmed] 10187796 [Medline] 99214571 The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999] | 2uniprot[Pubmed] 11094342 [Medline] 20547809 A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000] | [pubmed all]
|
33
|
Q93H87_STRAW (Q93H87) |
|
(10 hsp) |
0.0 |
2216 |
51% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA1
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
35
|
Q82QT4_STRAW (Q82QT4) |
|
(12 hsp) |
0.0 |
2214 |
51% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA1
SAV419 SAV_419
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
36
|
E0D206_9ACTO (E0D206) |
|
(3 hsp) |
0.0 |
2214 |
51% |
|
- Product
- Polyketide synthase
- Gene
- gfsE
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
38
|
Q84G23_STRHY (Q84G23) |
|
(5 hsp) |
0.0 |
2212 |
49% |
|
- Product
- GdmAII
- Gene
- gdmAII
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 12586396 [Medline] 22474162 Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003] |
|
42
|
Q52V50_9ACTO (Q52V50) |
|
(10 hsp) |
0.0 |
2207 |
51% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
44
|
Q1L0T1_STRHY (Q1L0T1) |
|
(5 hsp) |
0.0 |
2206 |
49% |
|
- Product
- GelB
- Gene
-
- Organism
- Streptomyces hygroscopicus subsp. duamyceticus
|
1uniprot[Pubmed] 18600054 Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008] |
|
46
|
A4FH85_SACEN (A4FH85) |
|
(9 hsp) |
0.0 |
2205 |
50% |
|
- Product
- Type I modular polyketide synthase
- Gene
- SACE_4141
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
47
|
Q5VKQ3_SACER (Q5VKQ3) |
|
(9 hsp) |
0.0 |
2205 |
50% |
|
- Product
- Type I PKS
- Gene
- pkeAI
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15925898 A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004] |
|
48
|
Q30CR9_STRAU (Q30CR9) |
|
(4 hsp) |
0.0 |
2205 |
49% |
|
- Product
- LipPks4
- Gene
- lipPks4
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 16723573 Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006] |
|
51
|
F1CLC1_9ACTO (F1CLC1) |
|
(10 hsp) |
0.0 |
2200 |
51% |
|
- Product
- ScnS1
- Gene
- scnS1
- Organism
- Streptomyces chattanoogensis
|
1uniprot[Pubmed] 21330439 The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011] |
|
52
|
Q52V46_9ACTO (Q52V46) |
|
(13 hsp) |
0.0 |
2196 |
48% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
53
|
Q6JHN6_9PSEU (Q6JHN6) |
|
(9 hsp) |
0.0 |
2194 |
51% |
|
- Product
- ObsC
- Gene
-
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 15346767 Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004] |
|
54
|
B3TMQ8_9ACTO (B3TMQ8) |
|
(9 hsp) |
0.0 |
2191 |
52% |
|
- Product
- Polyketide synthase
- Gene
- KijS1
- Organism
- Actinomadura kijaniata
|
1uniprot[Pubmed] 17985890 Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007] |
|
55
|
A1YAN0_AMYOR (A1YAN0) |
|
(5 hsp) |
0.0 |
2188 |
51% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 17136886 Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006] |
|
56
|
Q1WEK9_9ACTO (Q1WEK9) |
|
(11 hsp) |
0.0 |
2184 |
52% |
|
- Product
- Polyketide synthase
- Gene
- merA
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
57
|
Q93NW6_9ACTO (Q93NW6) |
|
(12 hsp) |
0.0 |
2183 |
52% |
|
- Product
- AmphC
- Gene
- amphC
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|
58
|
F1CLA9_9ACTO (F1CLA9) |
|
(14 hsp) |
0.0 |
2182 |
49% |
|
- Product
- ScnS2
- Gene
- scnS2
- Organism
- Streptomyces chattanoogensis
|
1uniprot[Pubmed] 21330439 The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011] |
|
60
|
D7BRD4_STRBB (D7BRD4) |
|
(12 hsp) |
0.0 |
2177 |
51% |
|
- Product
- Short-chain dehydrogenase/reductase SDR
- Gene
- SBI_01976
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
61
|
Q9EX53_STRCO (Q9EX53) |
|
(3 hsp) |
0.0 |
2175 |
48% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCO6274
- Organism
- Streptomyces coelicolor
|
1uniprot[Pubmed] 12000953 [Medline] 21996410 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002] |
|
63
|
F1CT52_9ACTO (F1CT52) |
|
(4 hsp) |
0.0 |
2174 |
49% |
|
- Product
- GdmAII
- Gene
- gdmAII
- Organism
- Streptomyces autolyticus
|
1uniprot[Pubmed] 21544574 Streptomyces autolyticus JX-47 Large-Insert Bacterial Artificial Chromosome Library Construction and Identification of Clones Covering Geldanamycin Biosynthesis Gene Cluster.(Curr. Microbiol.) [2011] |
|
64
|
D7BSN6_STRBB (D7BSN6) |
|
(4 hsp) |
0.0 |
2173 |
50% |
|
- Product
- Modular polyketide synthase
- Gene
- nanA5
SBI_08415
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
65
|
F8QPG1_9ACTO (F8QPG1) |
|
(3 hsp) |
0.0 |
2173 |
51% |
|
- Product
- Polyketide synthase
- Gene
- natD
- Organism
- Streptomyces sp. CS
|
1uniprot[Pubmed] 21614382 Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011] |
|
67
|
C6WNV0_ACTMD (C6WNV0) |
|
(5 hsp) |
0.0 |
2172 |
52% |
|
- Product
- Short-chain dehydrogenase/reductase SDR
- Gene
- Amir_2684
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
68
|
Q7WTF1_9ACTO (Q7WTF1) |
|
(4 hsp) |
0.0 |
2170 |
50% |
|
- Product
- NanA5
- Gene
- nanA5
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12770825 [Medline] 22654646 A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin.(Chem. Biol.) [2003] |
|
69
|
Q0R4M7_STRAT (Q0R4M7) |
|
(5 hsp) |
0.0 |
2167 |
48% |
|
- Product
- ChlA2
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006] |
|
70
|
Q52V44_9ACTO (Q52V44) |
|
(9 hsp) |
0.0 |
2167 |
47% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
71
|
B6ZIR3_STRPT (B6ZIR3) |
|
(8 hsp) |
0.0 |
2166 |
49% |
|
- Product
- Polyketide synthase
- Gene
- pldAII
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
72
|
Q9L4W3_9ACTO (Q9L4W3) |
|
(15 hsp) |
0.0 |
2165 |
52% |
|
- Product
- NysC
- Gene
- nysC
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
73
|
C6W8V0_ACTMD (C6W8V0) |
|
(2 hsp) |
0.0 |
2162 |
52% |
|
- Product
- Acyl transferase
- Gene
- Amir_3293
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
74
|
Q52V53_9ACTO (Q52V53) |
|
(8 hsp) |
0.0 |
2162 |
49% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
75
|
D7CC08_STRBB (D7CC08) |
|
(8 hsp) |
0.0 |
2161 |
51% |
|
- Product
- Putative type I polyketide synthase
- Gene
- pks5-2
SBI_01382
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
76
|
Q93NX9_9ACTO (Q93NX9) |
|
(14 hsp) |
0.0 |
2160 |
49% |
|
- Product
- AmphI
- Gene
- amphI
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|
77
|
Q6W5Q0_9ACTO (Q6W5Q0) |
|
(13 hsp) |
0.0 |
2160 |
51% |
|
- Product
- FscC
- Gene
- fscC
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
78
|
Q49BE0_STRHY (Q49BE0) |
|
(5 hsp) |
0.0 |
2159 |
49% |
|
- Product
- HbmAII
- Gene
- hbmAII
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 16085885 Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.(Appl. Environ. Microbiol.) [2005] |
|
79
|
Q68BG4_STRHA (Q68BG4) |
|
(12 hsp) |
0.0 |
2157 |
50% |
|
- Product
- Type I polyketide synthase
- Gene
- hlsB
- Organism
- Streptomyces halstedii
|
1uniprot Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004] |
|
81
|
Q52V52_9ACTO (Q52V52) |
|
(7 hsp) |
0.0 |
2155 |
51% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
82
|
Q1WEK8_9ACTO (Q1WEK8) |
|
(8 hsp) |
0.0 |
2155 |
50% |
|
- Product
- Polyketide synthase
- Gene
- merB
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
83
|
Q9ALM3_9PSEU (Q9ALM3) |
|
(6 hsp) |
0.0 |
2154 |
49% |
|
- Product
- Polyketide synthase extender modules 5-7
- Gene
- spnD
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001] |
|
84
|
E4NJF3_KITSK (E4NJF3) |
|
(4 hsp) |
0.0 |
2150 |
51% |
|
- Product
- Modular polyketide synthase BFAS3
- Gene
- bfmA3
KSE_73460
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
85
|
D3U9Y6_9ACTO (D3U9Y6) |
|
(6 hsp) |
0.0 |
2149 |
52% |
|
- Product
- Type I polyketide synthase
- Gene
- sfaF
- Organism
- Streptomyces flaveolus
|
1uniprot Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010] |
|
86
|
A0FCL1_STRVO (A0FCL1) |
|
(12 hsp) |
0.0 |
2149 |
52% |
|
- Product
- MerA
- Gene
- merA
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
87
|
D3Y1I5_9ACTO (D3Y1I5) |
|
(4 hsp) |
0.0 |
2149 |
50% |
|
- Product
- TamAIII
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
89
|
F1DI33_9ACTO (F1DI33) |
|
(4 hsp) |
0.0 |
2148 |
50% |
|
- Product
- TrdAIII
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
91
|
D7C2B8_STRBB (D7C2B8) |
|
(12 hsp) |
0.0 |
2144 |
50% |
|
- Product
- Type I modular polyketide synthase
- Gene
- pks3-2
SBI_00651
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
92
|
C0SMW4_9ACTO (C0SMW4) |
|
(13 hsp) |
0.0 |
2143 |
50% |
|
- Product
- Type I modular polyketide synthase
- Gene
- ttmJ
- Organism
- Streptomyces spiroverticillatus
|
1uniprot[Pubmed] 16707708 Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006] | 2uniprot[Pubmed] 18708355 Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008] | [pubmed all]
|
94
|
Q82QT5_STRAW (Q82QT5) |
|
(4 hsp) |
0.0 |
2140 |
50% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA2
SAV418 SAV_418
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
95
|
Q9EWA1_9ACTO (Q9EWA1) |
|
(16 hsp) |
0.0 |
2139 |
49% |
|
- Product
- PimS2 protein
- Gene
- pimS2
- Organism
- Streptomyces natalensis
|
1uniprot[Pubmed] 11094342 [Medline] 20547809 A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000] |
|
96
|
Q846X2_STRCM (Q846X2) |
|
(5 hsp) |
0.0 |
2138 |
49% |
|
- Product
- Monensin polyketide synthase modules 7 and 8
- Gene
- monAV
- Organism
- Streptomyces cinnamonensis
|
1uniprot[Pubmed] 12940979 [Medline] 22823264 Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization.(Mol. Microbiol.) [2003] | 2uniprot The gene cluster for monensin biosynthesis. [1999] |
|
98
|
D8HZ82_AMYMU (D8HZ82) |
|
(7 hsp) |
0.0 |
2135 |
52% |
|
- Product
- Rifamycin polyketide synthase
- Gene
- rifA
AMED_0617
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
99
|
O54666_AMYMD (O54666) |
|
(7 hsp) |
0.0 |
2135 |
52% |
|
- Product
- RifA
Rifamycin polyketide synthase, type 1
- Gene
- rifA
- Organism
- Amycolatopsis mediterranei
Nocardia mediterranei
|
1uniprot[Pubmed] 9512878 [Medline] 98174059 Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998] | 2uniprot[Pubmed] 9497318 [Medline] 98165773 3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998] | 3uniprot[Pubmed] 11278540 [Medline] 21201076 Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001] | [pubmed all]
|
100
|
D7C2C3_STRBB (D7C2C3) |
|
(6 hsp) |
0.0 |
2131 |
48% |
|
- Product
- Modular polyketide synthase
- Gene
- pks3-4
SBI_00656
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|