BLAST table : Ncarz_00280

DB	UniProtKB

	accession	Evalue	Score	Ident.	link	product	gene	organism
1	Q84HA6_STRCZ (Q84HA6)	0.0	709	100%	UniProt GenBank	Transcriptional regulator		Streptomyces carzinostaticus subsp. neocarzinostaticus
2	B4VAS3_9ACTO (B4VAS3)	1e-102	377	57%	UniProt GenBank	StrR	SSAG_04927	Streptomyces sp. Mg1
3	D6AAD8_9ACTO (D6AAD8)	5e-98	362	58%	UniProt GenBank	Transcriptional regulator	SSFG_07708	Streptomyces ghanaensis ATCC 14672
4	Q8GME5_STRGL (Q8GME5)	1e-91	341	54%	UniProt GenBank	Regulatory protein		Streptomyces globisporus
5	Q54267_STRGA (Q54267)	7e-61	239	44%	UniProt GenBank	StrR StrR protein	strR	Streptomyces glaucescens
6	Q8GI86_STRKA (Q8GI86)	9e-60	235	41%	UniProt GenBank	Transcriptional regulator protein	kasT	Streptomyces kasugaensis
7	A7VMW2_STRKA (A7VMW2)	1e-59	234	41%	UniProt GenBank	Putative transcriptional regulator	kasT	Streptomyces kasugaensis
8	D9W4I4_9ACTO (D9W4I4)	8e-58	229	43%	UniProt GenBank	Streptomycin biosynthesis operon regulator	SSNG_07064	Streptomyces sp. C
9	D3Y168_STRPT (D3Y168)	9e-58	228	42%	UniProt GenBank	Streptomycin biosynthesis operon regulator	strR	Streptomyces platensis
10	B0BLP8_9ACTO (B0BLP8)	1e-57	228	45%	UniProt GenBank	Regulatory protein	mdpR1	Actinomadura madurae
11	D9XNK4_9ACTO (D9XNK4)	2e-57	228	43%	UniProt GenBank	Putative uncharacterized protein	SSRG_00961	Streptomyces griseoflavus Tu4000
12	B1W378_STRGG (B1W378)	4e-57	226	43%	UniProt GenBank	Streptomycin biosynthesis operon regulator	strR SGR_5931	Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
13	Q53ID1_STRGR (Q53ID1)	4e-57	226	43%	UniProt GenBank	Str/sts-gene cluster transcriptional regulator StrR	strR SG7F10.21	Streptomyces griseus subsp. griseus
14	STRR_STRGR (P08076)	4e-57	226	43%	UniProt GenBank	Streptomycin biosynthesis operon possible regulatory protein	strR	Streptomyces griseus
15	D8V3N4_ACTLG (D8V3N4)	1e-55	221	44%	UniProt GenBank	Transcriptional regulator		Actinoplanes liguriae
16	B5GYS9_STRCL (B5GYS9)	2e-55	220	43%	UniProt GenBank	StrR	SSCG_04680	Streptomyces clavuligerus ATCC 27064
17	Q6L744_STRKN (Q6L744)	6e-54	216	42%	UniProt GenBank	Putative regulator of gene expression Putative transcriptional regulatory protein Transcriptional regulator	kanR kanL	Streptomyces kanamyceticus
18	E9L1J5_9ZZZZ (E9L1J5)	9e-52	208	42%	UniProt GenBank	Putative uncharacterized protein	CA37-51	uncultured organism CA37
19	D5SLC8_STRCL (D5SLC8)	1e-51	208	42%	UniProt GenBank	Transcriptional regulator	strR SCLAV_p1235	Streptomyces clavuligerus ATCC 27064
20	C4NYJ5_9ACTO (C4NYJ5)	1e-51	208	39%	UniProt GenBank	SaqI	saqI	Micromonospora sp. Tu 6368
21	Q83XA1_STRRO (Q83XA1)	4e-50	203	40%	UniProt GenBank	StrR-like regulatory protein		Streptomyces rochei Streptomyces parvullus
22	F6K0Y3_9BACT (F6K0Y3)	4e-50	203	40%	UniProt GenBank	Streptomycin biosynthesis operon regulator		uncultured bacterium BAC AB649/1850
23	B5GVQ0_STRCL (B5GVQ0)	4e-49	200	40%	UniProt GenBank	Putative StrR-family transcriptional regulator StaQ	SCLAV_5334 SSCG_03543	Streptomyces clavuligerus ATCC 27064
24	E9L1T0_9ZZZZ (E9L1T0)	9e-49	198	41%	UniProt GenBank	Putative uncharacterized protein	CA915-38	uncultured organism CA915
25	E2D2E0_9BACT (E2D2E0)	1e-48	198	41%	UniProt GenBank	Transcriptional regulator		uncultured soil bacterium
26	B7T1B4_9BACT (B7T1B4)	1e-48	198	41%	UniProt GenBank	Veg1	veg1	uncultured soil bacterium
27	A4X6Y8_SALTO (A4X6Y8)	2e-48	197	39%	UniProt GenBank	ParB domain protein nuclease	Strop_2187	Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
28	Q6ZZH8_ACTTI (Q6ZZH8)	2e-48	197	41%	UniProt GenBank	Transcriptional regulator Transcriptional regulator, StrR family	tcp28	Actinoplanes teichomyceticus
29	D9WU16_9ACTO (D9WU16)	3e-48	197	40%	UniProt GenBank	Putative uncharacterized protein	SSOG_01976	Streptomyces himastatinicus ATCC 53653
30	Q799B3_9PSEU (Q799B3)	5e-48	196	41%	UniProt GenBank	StrR family transcriptional regulator	bbr	Amycolatopsis balhimycina
31	Q06Z07_9ACTO (Q06Z07)	8e-48	195	41%	UniProt GenBank	StrR-like regulatory protein		Streptomyces fungicidicus
32	Q06Z05_9ACTO (Q06Z05)	9e-48	195	39%	UniProt GenBank	Putative uncharacterized protein		Streptomyces fungicidicus
33	C4RL70_9ACTO (C4RL70)	2e-47	194	38%	UniProt GenBank	Putative uncharacterized protein	MCAG_05311	Micromonospora sp. ATCC 39149
34	D3Y151_STRPT (D3Y151)	2e-47	194	40%	UniProt GenBank	Putative cytoplasmic protein		Streptomyces platensis
35	E9L1K6_9ZZZZ (E9L1K6)	2e-47	194	39%	UniProt GenBank	Putative uncharacterized protein	CA878-7	uncultured organism CA878
36	Q9XBC5_AMYOR (Q9XBC5)	3e-47	194	39%	UniProt GenBank	Putative transcriptional regulator	CZA382.26	Amycolatopsis orientalis Nocardia orientalis
37	Q7WZ87_9ACTO (Q7WZ87)	3e-47	193	40%	UniProt GenBank	Putative regulator StrR family	dbv4	Nonomuraea sp. ATCC 39727
38	F8STX0_AMYOR (F8STX0)	9e-47	192	40%	UniProt GenBank	StrR family transcriptional regulator	vtrR	Amycolatopsis orientalis Nocardia orientalis
39	E9L1I5_9ZZZZ (E9L1I5)	2e-46	191	41%	UniProt GenBank	Putative uncharacterized protein	CA37-41	uncultured organism CA37
40	D6A435_9ACTO (D6A435)	3e-46	190	36%	UniProt GenBank	Str/sts-gene cluster transcriptional regulator StrR	SSFG_06826	Streptomyces ghanaensis ATCC 14672
41	F8JU13_STRCT (F8JU13)	5e-46	189	37%	UniProt GenBank	Putative Streptomycin biosynthesis operon regulatory protein	strR SCAT_5797	Streptomyces cattleya
42	Q8KLK0_STRTO (Q8KLK0)	5e-46	189	38%	UniProt GenBank	StaQ		Streptomyces toyocaensis
43	B1VT26_STRGG (B1VT26)	1e-45	188	38%	UniProt GenBank	Putative StrR-family transcriptional regulator	SGR_901	Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
44	E2D2L7_9BACT (E2D2L7)	1e-45	188	37%	UniProt GenBank	Transcriptional regulator		uncultured soil bacterium
45	E4N404_KITSK (E4N404)	2e-45	187	41%	UniProt GenBank	Putative regulatory protein	KSE_00840t KSE_75900t	Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054) Streptomyces setae
46	F2RB72_STRVP (F2RB72)	6e-45	186	38%	UniProt GenBank	Transcriptional regulator protein	SVEN_0913	Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
47	E9L1J6_9ZZZZ (E9L1J6)	6e-45	186	39%	UniProt GenBank	Putative uncharacterized protein	CA37-52	uncultured organism CA37
48	B7T1C6_9BACT (B7T1C6)	4e-43	180	37%	UniProt GenBank	Teg1	teg1	uncultured soil bacterium
49	D7B8A0_NOCDD (D7B8A0)	5e-43	179	37%	UniProt GenBank	ParB domain protein nuclease	Ndas_5027	Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei
50	Q93N91_STRLA (Q93N91)	5e-43	179	38%	UniProt GenBank	Transcriptional regulator		Streptomyces lavendulae
51	F8JQK5_STRCT (F8JQK5)	2e-42	177	39%	UniProt GenBank	Putative Streptomycin biosynthesis operon regulatory protein	strR SCAT_5483	Streptomyces cattleya
52	Q2JA59_FRASC (Q2JA59)	6e-42	176	37%	UniProt GenBank	ParB-like nuclease	Francci3_2466	Frankia sp. (strain CcI3)
53	P72440_STRNE (P72440)	6e-41	172	35%	UniProt GenBank	SpcR	spcR	Streptoverticillium netropsis Streptoverticillium flavopersicus
54	Q27YR9_STRHY (Q27YR9)	7e-41	172	34%	UniProt GenBank	Putative regulatory protein		Streptomyces hygroscopicus
55	E2D2I0_9BACT (E2D2I0)	9e-41	172	40%	UniProt GenBank	Transcriptional regulator		uncultured soil bacterium
56	Q8GHC9_9ACTO (Q8GHC9)	2e-40	171	36%	UniProt GenBank	Regulatory protein cloG	cloG	Streptomyces roseochromogenes subsp. oscitans
57	Q9F8V4_9ACTO (Q9F8V4)	4e-38	163	35%	UniProt GenBank	CouG	couG	Streptomyces rishiriensis
58	Q9L9G1_STRSH (Q9L9G1)	3e-37	160	38%	UniProt GenBank	NovG	novG	Streptomyces spheroides Streptomyces caeruleus
59	C0SMX6_9ACTO (C0SMX6)	1e-32	145	34%	UniProt GenBank	Predicted transcriptional regulator protein	ttmQ	Streptomyces spiroverticillatus
60	Q54253_STRGR (Q54253)	3e-25	120	46%	UniProt GenBank	SPH and AT genes for streptomycinphosphotransferase and amidinotransferase		Streptomyces griseus
61	D6M4J1_9ACTO (D6M4J1)	1e-18	98.6	45%	UniProt GenBank	Putative uncharacterized protein	SSBG_05958	Streptomyces sp. SPB74
62	E8QZ66_ISOPI (E8QZ66)	4e-05	53.9	29%	UniProt GenBank	Putative uncharacterized protein	Isop_2638	Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B)

accession

alignment

Evalue

Score

Ident.

link

information

pubmed

Q84HA6_STRCZ
(Q84HA6)

0.0

709

100%

Product: Transcriptional regulator
Gene
Organism: Streptomyces carzinostaticus subsp. neocarzinostaticus

1uniprot[Pubmed] 15797213
The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases.(Chem. Biol.) [2005]

Q8GME5_STRGL
(Q8GME5)

1e-91

341

54%

Product: Regulatory protein
Gene
Organism: Streptomyces globisporus

1uniprot[Pubmed] 12183628 [Medline] 22171413
Biosynthesis of the enediyne antitumor antibiotic C-1027.(Science) [2002]

Q54267_STRGA
(Q54267)

7e-61

239

44%

Product: StrR
StrR protein
Gene: strR
Organism: Streptomyces glaucescens

1uniprot[Pubmed] 8628239 [Medline] 96204519
The str gene cluster for the biosynthesis of 5'-hydroxystreptomycin in Streptomyces glaucescens GLA.0 (ETH 22794): new operons and evidence for pathway-specific regulation by StrR.(Mol. Gen. Genet.) [1996]

2uniprot
Streptomycin Production in Streptomycetes: a Progress Report.(INDUSTRIAL MICROORGANISMS. BASIC AND APPLIED MOLECULAR GENETICS) [1993]

Q8GI86_STRKA
(Q8GI86)

9e-60

235

41%

Product: Transcriptional regulator protein
Gene: kasT
Organism: Streptomyces kasugaensis

1uniprot[Pubmed] 12617515 [Medline] 22504381
kasT gene of Streptomyces kasugaensis M338-M1 encodes a DNA-binding protein which binds to intergenic region of kasU-kasJ in the kasugamycin biosynthesis gene cluster.(J. Antibiot.) [2002]

D3Y168_STRPT
(D3Y168)

9e-58

228

42%

Product: Streptomycin biosynthesis operon regulator
Gene: strR
Organism: Streptomyces platensis

1uniprot[Pubmed] 20067498
Coevolution of antibiotic production and counter-resistance in soil bacteria.(Environ. Microbiol.) [2010]

B0BLP8_9ACTO
(B0BLP8)

1e-57

228

45%

Product: Regulatory protein
Gene: mdpR1
Organism: Actinomadura madurae

[pubmed all]
1uniprot[Pubmed] 14528002 [Medline] 22922109 Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model.(Proc. Natl. Acad. Sci. U.S.A.) [2003]
2uniprot[Pubmed] 17918933 Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis.(J. Am. Chem. Soc.) [2007]

B1W378_STRGG
(B1W378)

4e-57

226

43%

Product: Streptomycin biosynthesis operon regulator
Gene: strR
SGR_5931
Organism: Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)

1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]

STRR_STRGR
(P08076)

4e-57

226

43%

Product: Streptomycin biosynthesis operon possible regulatory protein
Gene: strR
Organism: Streptomyces griseus

1uniprot[Pubmed] 3118332 [Medline] 88040426
Gene cluster for streptomycin biosynthesis in Streptomyces griseus: nucleotide sequence of three genes and analysis of transcriptional activity.(Nucleic Acids Res.) [1987]

Q6L744_STRKN
(Q6L744)

6e-54

216

42%

Product: Putative regulator of gene expression
Putative transcriptional regulatory protein
Transcriptional regulator
Gene: kanR
kanL
Organism: Streptomyces kanamyceticus

[pubmed all]
1uniprot[Pubmed] 15303497 The kanamycin biosynthetic gene cluster from Streptomyces kanamyceticus.(J. Antibiot.) [2004]
2uniprot[Pubmed] 15313224 A gene cluster for biosynthesis of kanamycin from Streptomyces kanamyceticus: comparison with gentamicin biosynthetic gene cluster.(Arch. Biochem. Biophys.) [2004]

E9L1J5_9ZZZZ
(E9L1J5)

9e-52

208

42%

Product: Putative uncharacterized protein
Gene: CA37-51
Organism: uncultured organism CA37

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

D5SLC8_STRCL
(D5SLC8)

1e-51

208

42%

Product: Transcriptional regulator
Gene: strR
SCLAV_p1235
Organism: Streptomyces clavuligerus ATCC 27064

1uniprot
The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]

C4NYJ5_9ACTO
(C4NYJ5)

1e-51

208

39%

Product: SaqI
Gene: saqI
Organism: Micromonospora sp. Tu 6368

[pubmed all]
1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
2uniprot[Pubmed] 19384899 Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009]

Q83XA1_STRRO
(Q83XA1)

4e-50

203

40%

Product: StrR-like regulatory protein
Gene
Organism: Streptomyces rochei
Streptomyces parvullus

[pubmed all]
1uniprot[Pubmed] 12791134 [Medline] 22676866 The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175 Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737 Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144 Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]

B5GVQ0_STRCL
(B5GVQ0)

4e-49

200

40%

Product: Putative StrR-family transcriptional regulator
StaQ
Gene: SCLAV_5334
SSCG_03543
Organism: Streptomyces clavuligerus ATCC 27064

1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]

E9L1T0_9ZZZZ
(E9L1T0)

9e-49

198

41%

Product: Putative uncharacterized protein
Gene: CA915-38
Organism: uncultured organism CA915

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

E2D2E0_9BACT
(E2D2E0)

1e-48

198

41%

Product: Transcriptional regulator
Gene
Organism: uncultured soil bacterium

1uniprot[Pubmed] 20577994
Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.(Biopolymers) [2010]

B7T1B4_9BACT
(B7T1B4)

1e-48

198

41%

Product: Veg1
Gene: veg1
Organism: uncultured soil bacterium

1uniprot[Pubmed] 18987322
Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008]

Q6ZZH8_ACTTI
(Q6ZZH8)

2e-48

197

41%

Product: Transcriptional regulator
Transcriptional regulator, StrR family
Gene: tcp28
Organism: Actinoplanes teichomyceticus

[pubmed all]
1uniprot[Pubmed] 15113000 Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase.(Chem. Biol.) [2004]
2uniprot[Pubmed] 14702401 Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.(Microbiology) [2004]

Q799B3_9PSEU
(Q799B3)

5e-48

196

41%

Product: StrR family transcriptional regulator
Gene: bbr
Organism: Amycolatopsis balhimycina

[pubmed all]
1uniprot[Pubmed] 10390204 [Medline] 99318579 Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908.(Antimicrob. Agents Chemother.) [1999]
2uniprot[Pubmed] 11932455 [Medline] 21930292 Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules.(Microbiology) [2002]
3uniprot[Pubmed] 11495926 [Medline] 21486455 A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.(J. Biol. Chem.) [2001]
4uniprot[Pubmed] 12404385 The biosynthesis of vancomycin-type glycopeptide antibiotics - the order of cyclization steps.(Angew. Chem. Int. Ed. Engl.) [2001]
5uniprot[Pubmed] 11880037 [Medline] 21869276 Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.(Chem. Biol.) [2002]
6uniprot Precursor-directed biosynthesis for the generation of novel glycopetides.(Ernst Schering Res. Found. Workshop) [2005]

Q06Z07_9ACTO
(Q06Z07)

8e-48

195

41%

Product: StrR-like regulatory protein
Gene
Organism: Streptomyces fungicidicus

1uniprot[Pubmed] 17005978
The enduracidin biosynthetic gene cluster from Streptomyces fungicidicus.(Microbiology) [2006]

Q06Z05_9ACTO
(Q06Z05)

9e-48

195

39%

Product: Putative uncharacterized protein
Gene
Organism: Streptomyces fungicidicus

1uniprot[Pubmed] 17005978
The enduracidin biosynthetic gene cluster from Streptomyces fungicidicus.(Microbiology) [2006]

D3Y151_STRPT
(D3Y151)

2e-47

194

40%

Product: Putative cytoplasmic protein
Gene
Organism: Streptomyces platensis

1uniprot[Pubmed] 20067498
Coevolution of antibiotic production and counter-resistance in soil bacteria.(Environ. Microbiol.) [2010]

E9L1K6_9ZZZZ
(E9L1K6)

2e-47

194

39%

Product: Putative uncharacterized protein
Gene: CA878-7
Organism: uncultured organism CA878

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

Q7WZ87_9ACTO
(Q7WZ87)

3e-47

193

40%

Product: Putative regulator StrR family
Gene: dbv4
Organism: Nonomuraea sp. ATCC 39727

1uniprot[Pubmed] 12837387 [Medline] 22721464
The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003]

E9L1I5_9ZZZZ
(E9L1I5)

2e-46

191

41%

Product: Putative uncharacterized protein
Gene: CA37-41
Organism: uncultured organism CA37

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

Q8KLK0_STRTO
(Q8KLK0)

5e-46

189

38%

Product: StaQ
Gene
Organism: Streptomyces toyocaensis

[pubmed all]
1uniprot[Pubmed] 9177243 [Medline] 97322398 D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB.(Proc. Natl. Acad. Sci. U.S.A.) [1997]
2uniprot[Pubmed] 12060705 [Medline] 22080153 Assembling the glycopeptide antibiotic scaffold: the biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009.(Proc. Natl. Acad. Sci. U.S.A.) [2002]

B1VT26_STRGG
(B1VT26)

1e-45

188

38%

Product: Putative StrR-family transcriptional regulator
Gene: SGR_901
Organism: Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)

1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]

E2D2L7_9BACT
(E2D2L7)

1e-45

188

37%

Product: Transcriptional regulator
Gene
Organism: uncultured soil bacterium

1uniprot[Pubmed] 20577994
Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.(Biopolymers) [2010]

E4N404_KITSK
(E4N404)

2e-45

187

41%

Product: Putative regulatory protein
Gene: KSE_00840t
KSE_75900t
Organism: Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae

1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]

F2RB72_STRVP
(F2RB72)

6e-45

186

38%

Product: Transcriptional regulator protein
Gene: SVEN_0913
Organism: Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)

1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]

E9L1J6_9ZZZZ
(E9L1J6)

6e-45

186

39%

Product: Putative uncharacterized protein
Gene: CA37-52
Organism: uncultured organism CA37

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

B7T1C6_9BACT
(B7T1C6)

4e-43

180

37%

Product: Teg1
Gene: teg1
Organism: uncultured soil bacterium

1uniprot[Pubmed] 18987322
Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008]

D7B8A0_NOCDD
(D7B8A0)

5e-43

179

37%

Product: ParB domain protein nuclease
Gene: Ndas_5027
Organism: Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei

1uniprot
Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]

Q93N91_STRLA
(Q93N91)

5e-43

179

38%

Product: Transcriptional regulator
Gene
Organism: Streptomyces lavendulae

1uniprot[Pubmed] 11447274 [Medline] 21353013
Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2001]

Q2JA59_FRASC
(Q2JA59)

6e-42

176

37%

Product: ParB-like nuclease
Gene: Francci3_2466
Organism: Frankia sp. (strain CcI3)

1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]

P72440_STRNE
(P72440)

6e-41

172

35%

Product: SpcR
Gene: spcR
Organism: Streptoverticillium netropsis
Streptoverticillium flavopersicus

1uniprot[Pubmed] 9245803 [Medline] 97388569
A spectinomycin resistance determinant from the spectinomycin producer Streptomyces flavopersicus.(Microbiology)

Q27YR9_STRHY
(Q27YR9)

7e-41

172

34%

Product: Putative regulatory protein
Gene
Organism: Streptomyces hygroscopicus

1uniprot[Pubmed] 16873023
Production of hygromycin A analogs in Streptomyces hygroscopicus NRRL 2388 through identification and manipulation of the biosynthetic gene cluster.(Chem. Biol.) [2006]

E2D2I0_9BACT
(E2D2I0)

9e-41

172

40%

Product: Transcriptional regulator
Gene
Organism: uncultured soil bacterium

1uniprot[Pubmed] 20577994
Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.(Biopolymers) [2010]

Q8GHC9_9ACTO
(Q8GHC9)

2e-40

171

36%

Product: Regulatory protein cloG
Gene: cloG
Organism: Streptomyces roseochromogenes subsp. oscitans

1uniprot[Pubmed] 12480894 [Medline] 22368916
Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics.(Microbiology) [2002]

Q9F8V4_9ACTO
(Q9F8V4)

4e-38

163

35%

Product: CouG
Gene: couG
Organism: Streptomyces rishiriensis

1uniprot[Pubmed] 11036020 [Medline] 20493109
Identification of the coumermycin A(1) biosynthetic gene cluster of Streptomyces rishiriensis DSM 40489.(Antimicrob. Agents Chemother.) [2000]

Q9L9G1_STRSH
(Q9L9G1)

3e-37

160

38%

Product: NovG
Gene: novG
Organism: Streptomyces spheroides
Streptomyces caeruleus

1uniprot[Pubmed] 10770754 [Medline] 20233587
Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891.(Antimicrob. Agents Chemother.) [2000]

C0SMX6_9ACTO
(C0SMX6)

1e-32

145

34%

Product: Predicted transcriptional regulator protein
Gene: ttmQ
Organism: Streptomyces spiroverticillatus

[pubmed all]
1uniprot[Pubmed] 16707708 Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355 Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]

Q54253_STRGR
(Q54253)

3e-25

120

46%

Product: SPH and AT genes for streptomycinphosphotransferase and amidinotransferase
Gene
Organism: Streptomyces griseus

1uniprot[Pubmed] 3029728 [Medline] 87146497
Nucleotide sequence of the streptomycinphosphotransferase and amidinotransferase genes from Streptomyces griseus.(Nucleic Acids Res.) [1987]

E8QZ66_ISOPI
(E8QZ66)

4e-05

53.9

29%

Product: Putative uncharacterized protein
Gene: Isop_2638
Organism: Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B)

1uniprot
Complete genome sequence of Isosphaera pallida type strain (IS1B).(Stand. Genomic Sci.) [2011]