BLAST table : Lydi_00110

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 E0L044_STRVO
(E0L044)		 
[query] 1 - 7039 (7054)
[subject] 1 - 7209 (7224)
 0.0 7223   57% Beta-ketoacyl synthase StrviDRAFT_8272 Streptomyces violaceusniger Tu 4113
2
 D7BRD4_STRBB
(D7BRD4)		 
[query] 33 - 7054 (7054)
[subject] 2816 - 9950 (9950)
(8 hsp)		 0.0 6598   54% Short-chain dehydrogenase/reductase SDR SBI_01976 Streptomyces bingchenggensis (strain BCW-1)
3
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 29 - 7051 (7054)
[subject] 124 - 7106 (7110)
(3 hsp)		 0.0 6366   54% Short-chain dehydrogenase/reductase SDR Amir_2695 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
4
 A4X8L0_SALTO
(A4X8L0)		 
[query] 31 - 7054 (7054)
[subject] 171 - 7209 (7210)
(3 hsp)		 0.0 6329   53% Beta-ketoacyl synthase Strop_2768 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
5
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 33 - 6978 (7054)
[subject] 1788 - 8694 (10625)
(7 hsp)		 0.0 6292   54% FscC fscC Streptomyces sp. FR-008
6
 E8S0C5_MICSL
(E8S0C5)		 
[query] 30 - 6121 (7054)
[subject] 1590 - 7719 (9937)
(18 hsp)		 0.0 5723   54% Beta-ketoacyl synthase ML5_5898 Micromonospora sp. (strain L5)
7
 D9T6W4_MICAI
(D9T6W4)		 
[query] 30 - 6121 (7054)
[subject] 1590 - 7718 (9936)
(17 hsp)		 0.0 5721   54% Beta-ketoacyl synthase Micau_2464 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
8
 B3TMQ7_9ACTO
(B3TMQ7)		 
[query] 1 - 6988 (7054)
[subject] 1 - 6816 (6872)
(3 hsp)		 0.0 5597   49% Polyketide synthase KijS2 Actinomadura kijaniata
9
 B5L6K9_MICCH
(B5L6K9)		 
[query] 6 - 6966 (7054)
[subject] 9 - 6926 (7007)
(3 hsp)		 0.0 5523   49% Putative type I polyketide synthase Micromonospora chalcea
10
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 33 - 7047 (7054)
[subject] 6694 - 13937 (14130)
(13 hsp)		 0.0 5433   46% Type I modular polyketide synthase mlsB
MUP032c		 Mycobacterium ulcerans (strain Agy99)
11
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 1361 - 7054 (7054)
[subject] 5184 - 10917 (10917)
(6 hsp)		 0.0 5311   54% AmphC amphC Streptomyces nodosus
12
 Q82QT4_STRAW
(Q82QT4)		 
[query] 1293 - 7054 (7054)
[subject] 2082 - 7746 (7746)
(13 hsp)		 0.0 5296   54% Modular polyketide synthase pteA1
SAV419
SAV_419		 Streptomyces avermitilis
13
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 1286 - 7054 (7054)
[subject] 1105 - 6831 (6831)
(7 hsp)		 0.0 5276   54% ScnS1 scnS1 Streptomyces chattanoogensis
14
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 1286 - 7054 (7054)
[subject] 1091 - 6797 (6797)
(8 hsp)		 0.0 5236   54% PimS1 protein
Polyketide synthase		 pimS1 Streptomyces natalensis
15
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 1396 - 7052 (7054)
[subject] 5264 - 11094 (11096)
(7 hsp)		 0.0 5034   52% NysC nysC Streptomyces noursei
16
 Q52V52_9ACTO
(Q52V52)		 
[query] 1753 - 7054 (7054)
[subject] 35 - 5432 (5432)
(2 hsp)		 0.0 4958   54% Polyketide synthase type I Streptomyces aizunensis
17
 B4VDY6_9ACTO
(B4VDY6)		 
[query] 31 - 4798 (7054)
[subject] 17 - 4843 (4894)
(4 hsp)		 0.0 4944   57% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
18
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 1396 - 7013 (7054)
[subject] 5223 - 10829 (10876)
(6 hsp)		 0.0 4929   53% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
19
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 1747 - 7050 (7054)
[subject] 30 - 5176 (5176)
(2 hsp)		 0.0 4812   53% ObsB Saccharopolyspora spinosa
20
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 3 - 5206 (7054)
[subject] 1 - 5028 (5099)
(2 hsp)		 0.0 4794   54% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
21
 D1XUK5_9ACTO
(D1XUK5)		 
[query] 1750 - 6995 (7054)
[subject] 32 - 5107 (5157)
(2 hsp)		 0.0 4727   53% Short-chain dehydrogenase/reductase SDR SACTEDRAFT_6365 Streptomyces sp. SA3_actE
22
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 1751 - 7053 (7054)
[subject] 30 - 5321 (5321)
(2 hsp)		 0.0 4719   53% Polyketide synthase natC Streptomyces sp. CS
23
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 1752 - 7052 (7054)
[subject] 35 - 5337 (5339)
(2 hsp)		 0.0 4719   52% Polyketide synthase natB Streptomyces sp. CS
24
 D9VEY7_9ACTO
(D9VEY7)		 
[query] 1678 - 6981 (7054)
[subject] 53 - 5223 (5260)
(3 hsp)		 0.0 4715   53% Modular polyketide synthase SSMG_05939 Streptomyces sp. AA4
25
 E8WEN5_STRFA
(E8WEN5)		 
[query] 1750 - 6995 (7054)
[subject] 32 - 5106 (5156)
(2 hsp)		 0.0 4697   53% Beta-ketoacyl synthase Sfla_0979 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
26
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 1661 - 6973 (7054)
[subject] 901 - 5974 (6078)
(9 hsp)		 0.0 4650   53% ObsA Saccharopolyspora spinosa
27
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 1629 - 7054 (7054)
[subject] 903 - 6383 (6383)
(8 hsp)		 0.0 4611   49% Polyketide synthase type I mlaA1 Streptomyces sp. MP39-85
28
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 1378 - 7053 (7054)
[subject] 4890 - 10220 (10223)
(7 hsp)		 0.0 4596   49% Polyketide synthase rapB Streptomyces hygroscopicus
29
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 1743 - 6973 (7054)
[subject] 30 - 5110 (5400)
(2 hsp)		 0.0 4517   53% Short-chain dehydrogenase/reductase SDR Amir_2684 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
30
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 3 - 5219 (7054)
[subject] 1 - 5304 (5588)
(2 hsp)		 0.0 4516   51% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
31
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 1648 - 7052 (7054)
[subject] 914 - 6239 (6241)
(7 hsp)		 0.0 4476   50% Polyketide synthase KijS1 Actinomadura kijaniata
32
 E9KTB5_STRKN
(E9KTB5)		 
[query] 33 - 6970 (7054)
[subject] 1171 - 7536 (7591)
(5 hsp)		 0.0 4452   44% Polyketide synthase fkbB
Tcs_SK_031		 Streptomyces kanamyceticus
33
 B6CLY1_9MYCO
(B6CLY1)		 
[query] 1260 - 7047 (7054)
[subject] 6198 - 12159 (12352)
(12 hsp)		 0.0 4452   46% Type I modular polyketide synthase, MlsB mlsB
MULP_051		 Mycobacterium liflandii 128FXT
34
 A8M6C7_SALAI
(A8M6C7)		 
[query] 1752 - 6996 (7054)
[subject] 35 - 5204 (5255)
(2 hsp)		 0.0 4385   51% Beta-ketoacyl synthase Sare_1247 Salinispora arenicola (strain CNS-205)
35
 F1D8Z6_9ACTO
(F1D8Z6)		 
[query] 33 - 6960 (7054)
[subject] 1216 - 7585 (7655)
(5 hsp)		 0.0 4358   44% FkbB Streptomyces sp. MJM7001
36
 E9KTI2_9ACTO
(E9KTI2)		 
[query] 33 - 6960 (7054)
[subject] 1207 - 7576 (7646)
(5 hsp)		 0.0 4347   44% Polyketide synthase fkbB
Tcs_11604BP_028		 Streptomyces sp. KCTC 11604BP
37
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 1752 - 6976 (7054)
[subject] 35 - 5008 (5060)
(5 hsp)		 0.0 4333   50% Rifamycin polyketide synthase rifB
AMED_0618		 Amycolatopsis mediterranei (strain U-32)
38
 O52789_AMYMD
(O52789)		 
[query] 1752 - 6976 (7054)
[subject] 44 - 5017 (5069)
(5 hsp)		 0.0 4332   50% Rifamycin polyketide synthase, type 1 Amycolatopsis mediterranei
Nocardia mediterranei
39
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 1752 - 6976 (7054)
[subject] 35 - 5008 (5060)
(5 hsp)		 0.0 4328   50% RifB rifB Amycolatopsis mediterranei
Nocardia mediterranei
40
 Q9ZGA4_9ACTO
(Q9ZGA4)		 
[query] 33 - 6970 (7054)
[subject] 1183 - 7522 (7576)
(6 hsp)		 0.0 4318   44% FK506 polyketide synthase fkbB Streptomyces sp. MA6548
41
 F8JUL0_STRCT
(F8JUL0)		 
[query] 1640 - 6257 (7054)
[subject] 920 - 5432 (5950)
(12 hsp)		 0.0 4313   55% Putative polyketide synthase SCAT_3270 Streptomyces cattleya
42
 C6K7D8_9ACTO
(C6K7D8)		 
[query] 1379 - 7030 (7054)
[subject] 2791 - 7917 (7938)
(9 hsp)		 0.0 4289   48% Polyketide synthase rapA Actinoplanes sp. N902-109
43
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 3 - 4361 (7054)
[subject] 1 - 4473 (5214)
(9 hsp)		 0.0 4283   55% Polyketide synthase idmN Streptomyces antibioticus
44
 Q9S0R4_STRAW
(Q9S0R4)		 Jump to Aver_00080 
[query] 4 - 5200 (7054)
[subject] 3 - 5439 (5532)
(4 hsp)		 0.0 4276   50% Type I polyketide synthase AVES 3 aveA3
SAV942
SAV_942		 Streptomyces avermitilis
45
 B5L6K8_MICCH
(B5L6K8)		 
[query] 1652 - 7054 (7054)
[subject] 919 - 6305 (6305)
(6 hsp)		 0.0 4169   47% Putative type I polyketide synthase Micromonospora chalcea
46
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 4 - 4361 (7054)
[subject] 6 - 4550 (7026)
(9 hsp)		 0.0 4163   53% Polyketide synthase pldAII Streptomyces platensis
47
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 1640 - 6257 (7054)
[subject] 911 - 5575 (5582)
(9 hsp)		 0.0 4086   50% Polyketide synthase type I becA Streptomyces sp. DSM 21069
48
 Q0PCZ9_STRHA
(Q0PCZ9)		 Jump to Halsto_00060 
[query] 1725 - 6130 (7054)
[subject] 7 - 4510 (5232)
(8 hsp)		 0.0 4083   54% Type I polyketide synthase hlsF Streptomyces halstedii
49
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 1721 - 6126 (7054)
[subject] 4 - 4262 (8301)
(10 hsp)		 0.0 4083   56% Type I polyketide synthase sfaH Streptomyces flaveolus
50
 A8LUX2_SALAI
(A8LUX2)		 
[query] 1660 - 6124 (7054)
[subject] 905 - 5201 (7279)
(18 hsp)		 0.0 4050   53% Beta-ketoacyl synthase Sare_3156 Salinispora arenicola (strain CNS-205)
51
 B1W5P4_STRGG
(B1W5P4)		 
[query] 3 - 5199 (7054)
[subject] 1 - 4766 (4843)
(6 hsp)		 0.0 4048   47% Putative type-I PKS pks3-2
SGR_6372		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
52
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 30 - 4837 (7054)
[subject] 3799 - 8576 (10827)
(21 hsp)		 0.0 4035   51% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
53
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 30 - 4845 (7054)
[subject] 4138 - 8795 (9528)
(17 hsp)		 0.0 4011   51% Type I modular polyketide synthase ttnA Streptomyces griseochromogenes
54
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 30 - 4845 (7054)
[subject] 4254 - 8915 (9648)
(18 hsp)		 0.0 4007   51% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
55
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 5 - 4838 (7054)
[subject] 3 - 4507 (6260)
(14 hsp)		 0.0 3911   50% Polyketide synthase rapC Streptomyces hygroscopicus
56
 C0Z477_STRVN
(C0Z477)		 
[query] 1199 - 6127 (7054)
[subject] 536 - 5377 (6130)
(11 hsp)		 0.0 3889   50% Type I polyketide synthase, loading module and modules 1-3 ken16 Streptomyces violaceoruber
57
 F4F7F4_VERMA
(F4F7F4)		 
[query] 33 - 5205 (7054)
[subject] 955 - 5754 (5781)
(14 hsp)		 0.0 3847   48% Modular polyketide synthase VAB18032_16435 Verrucosispora maris (strain AB-18-032)
58
 F8JVX1_STRCT
(F8JVX1)		 
[query] 1650 - 6121 (7054)
[subject] 940 - 5399 (6125)
(12 hsp)		 0.0 3835   50% Putative 6-methylsalicylic acid synthase SCAT_0136 Streptomyces cattleya 2.3.1.165

2.3.1.94
59
 Q52V50_9ACTO
(Q52V50)		 
[query] 1361 - 5207 (7054)
[subject] 3538 - 7435 (7510)
(8 hsp)		 0.0 3821   57% Polyketide synthase type I Streptomyces aizunensis
60
 Q9KIE0_STRHY
(Q9KIE0)		 Jump to Asco_00140 
[query] 1653 - 6992 (7054)
[subject] 1067 - 5964 (7525)
(8 hsp)		 0.0 3766   47% FkbB fkbB Streptomyces hygroscopicus subsp. ascomyceticus
61
 Q52V53_9ACTO
(Q52V53)		 
[query] 1311 - 5199 (7054)
[subject] 1143 - 5127 (5207)
(9 hsp)		 0.0 3670   54% Polyketide synthase type I Streptomyces aizunensis
62
 D7F1M0_9ACTO
(D7F1M0)		 
[query] 1 - 4379 (7054)
[subject] 1 - 4408 (5136)
(8 hsp)		 0.0 3656   49% Polyketide synthase tsnAII Streptomyces longisporoflavus
63
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 3105 - 6973 (7054)
[subject] 3396 - 7196 (7488)
(10 hsp)		 0.0 3633   55% ObsC Saccharopolyspora spinosa
64
 D9VBL5_9ACTO
(D9VBL5)		 
[query] 30 - 4165 (7054)
[subject] 979 - 5012 (5113)
(12 hsp)		 0.0 3631   51% Modular polyketide synthase SSMG_01148 Streptomyces sp. AA4
65
 Q76KY0_STRHA
(Q76KY0)		 Jump to Vicen_00200 
[query] 1410 - 5200 (7054)
[subject] 1871 - 5745 (5826)
(8 hsp)		 0.0 3621   54% Polyketide synthase modules 1-3 vinP1 Streptomyces halstedii
66
 B4VB11_9ACTO
(B4VB11)		 
[query] 1438 - 5199 (7054)
[subject] 4 - 3842 (3928)
(4 hsp)		 0.0 3605   56% Polyketide synthase type I SSAG_04921 Streptomyces sp. Mg1
67
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 35 - 4860 (7054)
[subject] 20 - 5062 (16990)
(25 hsp)		 0.0 3586   44% Type I modular polyketide synthase mlsA1
MUP040c		 Mycobacterium ulcerans (strain Agy99)
68
 Q52V49_9ACTO
(Q52V49)		 
[query] 5 - 3497 (7054)
[subject] 2 - 3611 (3872)
(4 hsp)		 0.0 3581   58% Polyketide synthase type I Streptomyces aizunensis
69
 Q93H87_STRAW
(Q93H87)		 
[query] 1293 - 5195 (7054)
[subject] 2082 - 5959 (6048)
(13 hsp)		 0.0 3569   53% Modular polyketide synthase pteA1 Streptomyces avermitilis
70
 D7P611_CHOCO
(D7P611)		 
[query] 483 - 4860 (7054)
[subject] 988 - 5491 (6255)
(14 hsp)		 0.0 3568   48% TugA tugA Chondromyces crocatus
71
 Q30CS0_STRAU
(Q30CS0)		 Jump to Alip_00150 
[query] 3 - 3464 (7054)
[subject] 1 - 3535 (3612)
(3 hsp)		 0.0 3524   56% LipPks3 lipPks3 Streptomyces aureofaciens
72
 F8AWN2_9ACTO
(F8AWN2)		 
[query] 33 - 4364 (7054)
[subject] 1235 - 5926 (6077)
(17 hsp)		 0.0 3514   47% (Acyl-carrier-protein) S-acetyltransferase., 6-deoxyerythronolide-B synthase FsymDg_1936 Frankia symbiont of Datisca glomerata 2.3.1.38

2.3.1.94
73
 Q0RIF5_FRAAA
(Q0RIF5)		 
[query] 1663 - 7053 (7054)
[subject] 918 - 6432 (6432)
(7 hsp)		 0.0 3496   44% Putative type I polyketide synthase FRAAL4072 Frankia alni (strain ACN14a) 2.3.1.-
74
 D6C477_9ACTO
(D6C477)		 Jump to Meili_00310 
[query] 1379 - 5199 (7054)
[subject] 1788 - 5734 (5822)
(7 hsp)		 0.0 3478   52% Modular polyketide synthase meiA3 Streptomyces nanchangensis
75
 Q2PC52_STRAH
(Q2PC52)		 Jump to Rubra_00380 
[query] 4 - 4636 (7054)
[subject] 3 - 4574 (5066)
(9 hsp)		 0.0 3445   47% Putative polyketide synthase rubB Streptomyces achromogenes subsp. rubradiris
76
 Q30CS1_STRAU
(Q30CS1)		 Jump to Alip_00140 
[query] 3455 - 7052 (7054)
[subject] 7 - 3582 (3582)
(3 hsp)		 0.0 3423   55% LipPks2 lipPks2 Streptomyces aureofaciens
77
 B6CLY8_9MYCO
(B6CLY8)		 
[query] 1754 - 6605 (7054)
[subject] 20 - 5041 (17019)
(26 hsp)		 0.0 3420   43% Type I modular polyketide synthase, MlsA1 mlsA1
MULP_065		 Mycobacterium liflandii 128FXT
78
 D7F1M1_9ACTO
(D7F1M1)		 
[query] 3090 - 7052 (7054)
[subject] 1706 - 5629 (5630)
(7 hsp)		 0.0 3402   50% Polyketide synthase tsnAIII Streptomyces longisporoflavus
79
 C5HV15_STRAT
(C5HV15)		 Jump to Indano_00170 
[query] 1 - 3460 (7054)
[subject] 1 - 3500 (3596)
(3 hsp)		 0.0 3402   55% Polyketide synthase idmM Streptomyces antibioticus
80
 Q82QT5_STRAW
(Q82QT5)		 
[query] 1752 - 5217 (7054)
[subject] 34 - 3492 (3564)
(4 hsp)		 0.0 3371   55% Modular polyketide synthase pteA2
SAV418
SAV_418		 Streptomyces avermitilis
81
 Q93H86_STRAW
(Q93H86)		 
[query] 1759 - 5217 (7054)
[subject] 1 - 3452 (3524)
(4 hsp)		 0.0 3359   55% Modular polyketide synthase pteA2 Streptomyces avermitilis
82
 Q0PD02_STRHA
(Q0PD02)		 Jump to Halsto_00030 
[query] 1123 - 5210 (7054)
[subject] 957 - 5145 (5220)
(8 hsp)		 0.0 3358   50% Type I polyketide synthase hlsC Streptomyces halstedii
83
 E0L075_STRVO
(E0L075)		 
[query] 3 - 3098 (7054)
[subject] 1 - 3161 (5786)
(13 hsp)		 0.0 3346   59% Beta-ketoacyl synthase StrviDRAFT_8303 Streptomyces violaceusniger Tu 4113
84
 E0D205_9ACTO
(E0D205)		 Jump to FD891_00040 
[query] 1752 - 5199 (7054)
[subject] 34 - 3542 (3639)
(3 hsp)		 0.0 3338   55% Polyketide synthase gfsD Streptomyces graminofaciens
85
 D6B4Q9_9ACTO
(D6B4Q9)		 
[query] 3033 - 6978 (7054)
[subject] 128 - 4013 (5945)
(8 hsp)		 0.0 3329   53% Polyketide synthase SSHG_00090 Streptomyces albus J1074
86
 E0L045_STRVO
(E0L045)		 
[query] 295 - 3463 (7054)
[subject] 1 - 3273 (3357)
(4 hsp)		 0.0 3327   58% Short-chain dehydrogenase/reductase SDR StrviDRAFT_8273 Streptomyces violaceusniger Tu 4113
87
 A8J704_9ACTO
(A8J704)		 
[query] 1378 - 5190 (7054)
[subject] 1724 - 5579 (5674)
(8 hsp)		 0.0 3327   52% Modular polyketide synthase nemA3 Streptomyces cyaneogriseus subsp. noncyanogenus
88
 Q0R4M5_STRAT
(Q0R4M5)		 Jump to Chth_00290 
[query] 3106 - 6973 (7054)
[subject] 1754 - 5630 (5718)
(9 hsp)		 0.0 3311   49% ChlA3 Streptomyces antibioticus
89
 C3VLW9_9ACTO
(C3VLW9)		 
[query] 3483 - 6999 (7054)
[subject] 37 - 3320 (3377)
(3 hsp)		 0.0 3291   54% Polyketide synthase type I becF Streptomyces sp. DSM 21069
90
 D7C2B8_STRBB
(D7C2B8)		 
[query] 1361 - 4840 (7054)
[subject] 3250 - 6733 (7498)
(18 hsp)		 0.0 3290   54% Type I modular polyketide synthase pks3-2
SBI_00651		 Streptomyces bingchenggensis (strain BCW-1)
91
 D9WQL2_9ACTO
(D9WQL2)		 
[query] 5 - 3457 (7054)
[subject] 4 - 3284 (3284)
(4 hsp)		 0.0 3278   55% Modular polyketide synthase SSOG_07859 Streptomyces himastatinicus ATCC 53653
92
 C3VLZ7_9ACTO
(C3VLZ7)		 
[query] 3483 - 6991 (7054)
[subject] 37 - 3308 (3373)
(4 hsp)		 0.0 3277   54% Polyketide synthase type I mlaF Streptomyces sp. MP39-85
93
 Q76KZ3_STRHA
(Q76KZ3)		 Jump to Vicen_00070 
[query] 3 - 3461 (7054)
[subject] 1 - 3498 (3808)
(5 hsp)		 0.0 3263   54% Polyketide synthase modules 7-8 vinP4 Streptomyces halstedii
94
 Q9EX53_STRCO
(Q9EX53)		 
[query] 3 - 3475 (7054)
[subject] 1 - 3508 (3576)
(3 hsp)		 0.0 3251   53% Putative type I polyketide synthase SCO6274 Streptomyces coelicolor
95
 Q1MX73_9ACTO
(Q1MX73)		 Jump to Tetrn_00160 
[query] 3103 - 7040 (7054)
[subject] 1730 - 5643 (5657)
(8 hsp)		 0.0 3244   49% Type I polyketide synthase tmnAIV Streptomyces sp. NRRL 11266
96
 C3VLV8_9ACTO
(C3VLV8)		 
[query] 1655 - 5199 (7054)
[subject] 3 - 3484 (3527)
(5 hsp)		 0.0 3244   53% Polyketide synthase type I becB Streptomyces sp. DSM 21069
97
 B6ZIR2_STRPT
(B6ZIR2)		 Jump to Pladi_00010 
[query] 1195 - 4834 (7054)
[subject] 1957 - 5751 (6532)
(17 hsp)		 0.0 3230   52% Polyketide synthase pldAI Streptomyces platensis
98
 D9WQ83_9ACTO
(D9WQ83)		 
[query] 3 - 2937 (7054)
[subject] 10 - 2997 (3002)
(5 hsp)		 0.0 3221   60% Modular polyketide synthase SSOG_05757 Streptomyces himastatinicus ATCC 53653
99
 C3VLY6_9ACTO
(C3VLY6)		 
[query] 1682 - 5199 (7054)
[subject] 38 - 3483 (3530)
(5 hsp)		 0.0 3219   53% Polyketide synthase type I mlaB Streptomyces sp. MP39-85
100
 D9T6W9_MICAI
(D9T6W9)		 
[query] 1743 - 5217 (7054)
[subject] 25 - 3584 (3649)
(3 hsp)		 0.0 3218   54% Acyl transferase Micau_2469 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
2
 D7BRD4_STRBB
(D7BRD4)		 
[query] 33 - 7054 (7054)
[subject] 2816 - 9950 (9950)
(8 hsp)		 0.0 6598   54%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_01976
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
3
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 29 - 7051 (7054)
[subject] 124 - 7106 (7110)
(3 hsp)		 0.0 6366   54%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2695
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
5
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 33 - 6978 (7054)
[subject] 1788 - 8694 (10625)
(7 hsp)		 0.0 6292   54%
Product
FscC
Gene
fscC
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
8
 B3TMQ7_9ACTO
(B3TMQ7)		 
[query] 1 - 6988 (7054)
[subject] 1 - 6816 (6872)
(3 hsp)		 0.0 5597   49%
Product
Polyketide synthase
Gene
KijS2
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
9
 B5L6K9_MICCH
(B5L6K9)		 
[query] 6 - 6966 (7054)
[subject] 9 - 6926 (7007)
(3 hsp)		 0.0 5523   49%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
10
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 33 - 7047 (7054)
[subject] 6694 - 13937 (14130)
(13 hsp)		 0.0 5433   46%
Product
Type I modular polyketide synthase
Gene
mlsB
MUP032c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
2uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
[pubmed all]
11
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 1361 - 7054 (7054)
[subject] 5184 - 10917 (10917)
(6 hsp)		 0.0 5311   54%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
12
 Q82QT4_STRAW
(Q82QT4)		 
[query] 1293 - 7054 (7054)
[subject] 2082 - 7746 (7746)
(13 hsp)		 0.0 5296   54%
Product
Modular polyketide synthase
Gene
pteA1
SAV419
SAV_419
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
13
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 1286 - 7054 (7054)
[subject] 1105 - 6831 (6831)
(7 hsp)		 0.0 5276   54%
Product
ScnS1
Gene
scnS1
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
14
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 1286 - 7054 (7054)
[subject] 1091 - 6797 (6797)
(8 hsp)		 0.0 5236   54%
Product
PimS1 protein
Polyketide synthase
Gene
pimS1
Organism
Streptomyces natalensis
1uniprot[Pubmed] 10187796 [Medline] 99214571
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999]
2uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
[pubmed all]
15
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 1396 - 7052 (7054)
[subject] 5264 - 11094 (11096)
(7 hsp)		 0.0 5034   52%
Product
NysC
Gene
nysC
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
16
 Q52V52_9ACTO
(Q52V52)		 
[query] 1753 - 7054 (7054)
[subject] 35 - 5432 (5432)
(2 hsp)		 0.0 4958   54%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
18
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 1396 - 7013 (7054)
[subject] 5223 - 10829 (10876)
(6 hsp)		 0.0 4929   53%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
19
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 1747 - 7050 (7054)
[subject] 30 - 5176 (5176)
(2 hsp)		 0.0 4812   53%
Product
ObsB
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
20
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 3 - 5206 (7054)
[subject] 1 - 5028 (5099)
(2 hsp)		 0.0 4794   54%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
22
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 1751 - 7053 (7054)
[subject] 30 - 5321 (5321)
(2 hsp)		 0.0 4719   53%
Product
Polyketide synthase
Gene
natC
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
23
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 1752 - 7052 (7054)
[subject] 35 - 5337 (5339)
(2 hsp)		 0.0 4719   52%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
26
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 1661 - 6973 (7054)
[subject] 901 - 5974 (6078)
(9 hsp)		 0.0 4650   53%
Product
ObsA
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
27
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 1629 - 7054 (7054)
[subject] 903 - 6383 (6383)
(8 hsp)		 0.0 4611   49%
Product
Polyketide synthase type I
Gene
mlaA1
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
28
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 1378 - 7053 (7054)
[subject] 4890 - 10220 (10223)
(7 hsp)		 0.0 4596   49%
Product
Polyketide synthase
Gene
rapB
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
29
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 1743 - 6973 (7054)
[subject] 30 - 5110 (5400)
(2 hsp)		 0.0 4517   53%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2684
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
30
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 3 - 5219 (7054)
[subject] 1 - 5304 (5588)
(2 hsp)		 0.0 4516   51%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
31
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 1648 - 7052 (7054)
[subject] 914 - 6239 (6241)
(7 hsp)		 0.0 4476   50%
Product
Polyketide synthase
Gene
KijS1
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
32
 E9KTB5_STRKN
(E9KTB5)		 
[query] 33 - 6970 (7054)
[subject] 1171 - 7536 (7591)
(5 hsp)		 0.0 4452   44%
Product
Polyketide synthase
Gene
fkbB
Tcs_SK_031
Organism
Streptomyces kanamyceticus
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
33
 B6CLY1_9MYCO
(B6CLY1)		 
[query] 1260 - 7047 (7054)
[subject] 6198 - 12159 (12352)
(12 hsp)		 0.0 4452   46%
Product
Type I modular polyketide synthase, MlsB
Gene
mlsB
MULP_051
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
36
 E9KTI2_9ACTO
(E9KTI2)		 
[query] 33 - 6960 (7054)
[subject] 1207 - 7576 (7646)
(5 hsp)		 0.0 4347   44%
Product
Polyketide synthase
Gene
fkbB
Tcs_11604BP_028
Organism
Streptomyces sp. KCTC 11604BP
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
37
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 1752 - 6976 (7054)
[subject] 35 - 5008 (5060)
(5 hsp)		 0.0 4333   50%
Product
Rifamycin polyketide synthase
Gene
rifB
AMED_0618
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
39
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 1752 - 6976 (7054)
[subject] 35 - 5008 (5060)
(5 hsp)		 0.0 4328   50%
Product
RifB
Gene
rifB
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
40
 Q9ZGA4_9ACTO
(Q9ZGA4)		 
[query] 33 - 6970 (7054)
[subject] 1183 - 7522 (7576)
(6 hsp)		 0.0 4318   44%
Product
FK506 polyketide synthase
Gene
fkbB
Organism
Streptomyces sp. MA6548
1uniprot[Pubmed] 9780228 [Medline] 98451508
The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506.(Eur. J. Biochem.) [1998]
43
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 3 - 4361 (7054)
[subject] 1 - 4473 (5214)
(9 hsp)		 0.0 4283   55%
Product
Polyketide synthase
Gene
idmN
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
44
 Q9S0R4_STRAW
(Q9S0R4)		 Jump to Aver_00080 
[query] 4 - 5200 (7054)
[subject] 3 - 5439 (5532)
(4 hsp)		 0.0 4276   50%
Product
Type I polyketide synthase AVES 3
Gene
aveA3
SAV942
SAV_942
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 10449723 [Medline] 99380548
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999]
2uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
3uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
45
 B5L6K8_MICCH
(B5L6K8)		 
[query] 1652 - 7054 (7054)
[subject] 919 - 6305 (6305)
(6 hsp)		 0.0 4169   47%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
46
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 4 - 4361 (7054)
[subject] 6 - 4550 (7026)
(9 hsp)		 0.0 4163   53%
Product
Polyketide synthase
Gene
pldAII
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
47
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 1640 - 6257 (7054)
[subject] 911 - 5575 (5582)
(9 hsp)		 0.0 4086   50%
Product
Polyketide synthase type I
Gene
becA
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
49
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 1721 - 6126 (7054)
[subject] 4 - 4262 (8301)
(10 hsp)		 0.0 4083   56%
Product
Type I polyketide synthase
Gene
sfaH
Organism
Streptomyces flaveolus
1uniprot
Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010]
51
 B1W5P4_STRGG
(B1W5P4)		 
[query] 3 - 5199 (7054)
[subject] 1 - 4766 (4843)
(6 hsp)		 0.0 4048   47%
Product
Putative type-I PKS
Gene
pks3-2
SGR_6372
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
52
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 30 - 4837 (7054)
[subject] 3799 - 8576 (10827)
(21 hsp)		 0.0 4035   51%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
53
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 30 - 4845 (7054)
[subject] 4138 - 8795 (9528)
(17 hsp)		 0.0 4011   51%
Product
Type I modular polyketide synthase
Gene
ttnA
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
54
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 30 - 4845 (7054)
[subject] 4254 - 8915 (9648)
(18 hsp)		 0.0 4007   51%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
55
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 5 - 4838 (7054)
[subject] 3 - 4507 (6260)
(14 hsp)		 0.0 3911   50%
Product
Polyketide synthase
Gene
rapC
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
57
 F4F7F4_VERMA
(F4F7F4)		 
[query] 33 - 5205 (7054)
[subject] 955 - 5754 (5781)
(14 hsp)		 0.0 3847   48%
Product
Modular polyketide synthase
Gene
VAB18032_16435
Organism
Verrucosispora maris (strain AB-18-032)
1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]
59
 Q52V50_9ACTO
(Q52V50)		 
[query] 1361 - 5207 (7054)
[subject] 3538 - 7435 (7510)
(8 hsp)		 0.0 3821   57%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
60
 Q9KIE0_STRHY
(Q9KIE0)		 Jump to Asco_00140 
[query] 1653 - 6992 (7054)
[subject] 1067 - 5964 (7525)
(8 hsp)		 0.0 3766   47%
Product
FkbB
Gene
fkbB
Organism
Streptomyces hygroscopicus subsp. ascomyceticus
1uniprot[Pubmed] 10863099 [Medline] 20323220
The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.(Gene) [2000]
61
 Q52V53_9ACTO
(Q52V53)		 
[query] 1311 - 5199 (7054)
[subject] 1143 - 5127 (5207)
(9 hsp)		 0.0 3670   54%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
63
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 3105 - 6973 (7054)
[subject] 3396 - 7196 (7488)
(10 hsp)		 0.0 3633   55%
Product
ObsC
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
65
 Q76KY0_STRHA
(Q76KY0)		 Jump to Vicen_00200 
[query] 1410 - 5200 (7054)
[subject] 1871 - 5745 (5826)
(8 hsp)		 0.0 3621   54%
Product
Polyketide synthase modules 1-3
Gene
vinP1
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
67
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 35 - 4860 (7054)
[subject] 20 - 5062 (16990)
(25 hsp)		 0.0 3586   44%
Product
Type I modular polyketide synthase
Gene
mlsA1
MUP040c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
2uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
[pubmed all]
68
 Q52V49_9ACTO
(Q52V49)		 
[query] 5 - 3497 (7054)
[subject] 2 - 3611 (3872)
(4 hsp)		 0.0 3581   58%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
69
 Q93H87_STRAW
(Q93H87)		 
[query] 1293 - 5195 (7054)
[subject] 2082 - 5959 (6048)
(13 hsp)		 0.0 3569   53%
Product
Modular polyketide synthase
Gene
pteA1
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
70
 D7P611_CHOCO
(D7P611)		 
[query] 483 - 4860 (7054)
[subject] 988 - 5491 (6255)
(14 hsp)		 0.0 3568   48%
Product
TugA
Gene
tugA
Organism
Chondromyces crocatus
1uniprot[Pubmed] 20416506
Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010]
71
 Q30CS0_STRAU
(Q30CS0)		 Jump to Alip_00150 
[query] 3 - 3464 (7054)
[subject] 1 - 3535 (3612)
(3 hsp)		 0.0 3524   56%
Product
LipPks3
Gene
lipPks3
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 16723573
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006]
73
 Q0RIF5_FRAAA
(Q0RIF5)		 
[query] 1663 - 7053 (7054)
[subject] 918 - 6432 (6432)
(7 hsp)		 0.0 3496   44%
Product
Putative type I polyketide synthase
Gene
FRAAL4072
Organism
Frankia alni (strain ACN14a)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
74
 D6C477_9ACTO
(D6C477)		 Jump to Meili_00310 
[query] 1379 - 5199 (7054)
[subject] 1788 - 5734 (5822)
(7 hsp)		 0.0 3478   52%
Product
Modular polyketide synthase
Gene
meiA3
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
75
 Q2PC52_STRAH
(Q2PC52)		 Jump to Rubra_00380 
[query] 4 - 4636 (7054)
[subject] 3 - 4574 (5066)
(9 hsp)		 0.0 3445   47%
Product
Putative polyketide synthase
Gene
rubB
Organism
Streptomyces achromogenes subsp. rubradiris
1uniprot[Pubmed] 9387157 [Medline] 98048398
Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997]
2uniprot[Pubmed] 12889805 [Medline] 22771458
Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003]
[pubmed all]
76
 Q30CS1_STRAU
(Q30CS1)		 Jump to Alip_00140 
[query] 3455 - 7052 (7054)
[subject] 7 - 3582 (3582)
(3 hsp)		 0.0 3423   55%
Product
LipPks2
Gene
lipPks2
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 16723573
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006]
77
 B6CLY8_9MYCO
(B6CLY8)		 
[query] 1754 - 6605 (7054)
[subject] 20 - 5041 (17019)
(26 hsp)		 0.0 3420   43%
Product
Type I modular polyketide synthase, MlsA1
Gene
mlsA1
MULP_065
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
79
 C5HV15_STRAT
(C5HV15)		 Jump to Indano_00170 
[query] 1 - 3460 (7054)
[subject] 1 - 3500 (3596)
(3 hsp)		 0.0 3402   55%
Product
Polyketide synthase
Gene
idmM
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
80
 Q82QT5_STRAW
(Q82QT5)		 
[query] 1752 - 5217 (7054)
[subject] 34 - 3492 (3564)
(4 hsp)		 0.0 3371   55%
Product
Modular polyketide synthase
Gene
pteA2
SAV418
SAV_418
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
81
 Q93H86_STRAW
(Q93H86)		 
[query] 1759 - 5217 (7054)
[subject] 1 - 3452 (3524)
(4 hsp)		 0.0 3359   55%
Product
Modular polyketide synthase
Gene
pteA2
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
84
 E0D205_9ACTO
(E0D205)		 Jump to FD891_00040 
[query] 1752 - 5199 (7054)
[subject] 34 - 3542 (3639)
(3 hsp)		 0.0 3338   55%
Product
Polyketide synthase
Gene
gfsD
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
88
 Q0R4M5_STRAT
(Q0R4M5)		 Jump to Chth_00290 
[query] 3106 - 6973 (7054)
[subject] 1754 - 5630 (5718)
(9 hsp)		 0.0 3311   49%
Product
ChlA3
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
89
 C3VLW9_9ACTO
(C3VLW9)		 
[query] 3483 - 6999 (7054)
[subject] 37 - 3320 (3377)
(3 hsp)		 0.0 3291   54%
Product
Polyketide synthase type I
Gene
becF
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
90
 D7C2B8_STRBB
(D7C2B8)		 
[query] 1361 - 4840 (7054)
[subject] 3250 - 6733 (7498)
(18 hsp)		 0.0 3290   54%
Product
Type I modular polyketide synthase
Gene
pks3-2
SBI_00651
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
92
 C3VLZ7_9ACTO
(C3VLZ7)		 
[query] 3483 - 6991 (7054)
[subject] 37 - 3308 (3373)
(4 hsp)		 0.0 3277   54%
Product
Polyketide synthase type I
Gene
mlaF
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
93
 Q76KZ3_STRHA
(Q76KZ3)		 Jump to Vicen_00070 
[query] 3 - 3461 (7054)
[subject] 1 - 3498 (3808)
(5 hsp)		 0.0 3263   54%
Product
Polyketide synthase modules 7-8
Gene
vinP4
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
94
 Q9EX53_STRCO
(Q9EX53)		 
[query] 3 - 3475 (7054)
[subject] 1 - 3508 (3576)
(3 hsp)		 0.0 3251   53%
Product
Putative type I polyketide synthase
Gene
SCO6274
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
96
 C3VLV8_9ACTO
(C3VLV8)		 
[query] 1655 - 5199 (7054)
[subject] 3 - 3484 (3527)
(5 hsp)		 0.0 3244   53%
Product
Polyketide synthase type I
Gene
becB
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
97
 B6ZIR2_STRPT
(B6ZIR2)		 Jump to Pladi_00010 
[query] 1195 - 4834 (7054)
[subject] 1957 - 5751 (6532)
(17 hsp)		 0.0 3230   52%
Product
Polyketide synthase
Gene
pldAI
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
99
 C3VLY6_9ACTO
(C3VLY6)		 
[query] 1682 - 5199 (7054)
[subject] 38 - 3483 (3530)
(5 hsp)		 0.0 3219   53%
Product
Polyketide synthase type I
Gene
mlaB
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]