Chalc_00220 Chalc_00220   Chalc_00240 Chalc_00240

Chalc_00230 : CDS information

close this sectionLocation

Organism
StrainNRRL 2737
Entry nameChalcomycin
Contig
Start / Stop / Direction43,022 / 54,388 / + [in whole cluster]
43,022 / 54,388 / + [in contig]
Location43022..54388 [in whole cluster]
43022..54388 [in contig]
TypeCDS
Length11,367 bp (3,788 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category1.1 PKS
Productpolyketide synthase
Product (GenBank)polyketide synthase subunit
Gene
Gene (GenBank)chmGIII
EC number
Keyword
Note
Note (GenBank)
  • modules 4-5 KS/AT/KR/ACP/KS/AT/DH/ER/KR/ACP
Reference
ACC
PmId
[15561847] Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae. (Antimicrob Agents Chemother. , 2004)
comment
Chalcomycin biosynthesis gene clusterに関する文献。

chmGIII(3,788a.a.): PKS, modules 4 and 5

tyl PKS genesを削除したS.fradiae K159-1でchm PKS genesを発現すると、5-O-mycaminosylchalcolactone産生。よって、これらgenesはchalcomycin PKSであり、同定したclusterはchalcomycin生合成をする。

close this sectionPKS/NRPS Module

4 methylmalonyl-CoA
5 methylmalonyl-CoA
KS40..418
AT579..896
kr1160..1330
ACP1445..1515
KS1543..1919
AT2071..2387
DH2436..2635
ER3007..3312
KR3322..3503
ACP3619..3689

close this sectionSequence

selected fasta
>polyketide synthase [polyketide synthase subunit]
MSSTSPATNEEKLRDYLRRAMTDLHEAREQIRRTESARHEPIAIVGMGCRLPGGVSSPEG
LWDLVASGVDAVSPFPTDRGWDVGGLFDPEPGVPGRSYVREGGFLHEAGEFDAGFFGISP
REALAMDPQQRLLLETSWEALERAGIDPHTLRGSRTGVYAGVMYHDYGSTATVSVASDDE
TAGFLGTGTSGSVASGRISYVLGLEGPAVTVDTACSSSLVALHLAVRALRSGECDLALAG
GVTVMAEPGVFVEFSRQRGLAADGRCKAFAAAADGTGWAEGVGVLAVERLSDAVRHGRRV
LAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALADARLGVADVDVVEGHGTGTRLGDPI
EAQALLATYGQRDAGRALRLGSLKSNVGHTQAAAGVAGVIKMVMAMRHGVLPKTLHVDEP
TAEVDWSAGAVSLLREQEAWPEVGRLRRAAVSSFGVSGTNAHVVVEEAPASEAPVAGEPV
EPVEPGAVGLLPVVPVVVSGRSAGAVAELASRLNESVRSDRLVDVGLSSVVSRSVFEHRS
VVLAEDSAELHTGLVAVGTGVPSPGVVSGVASVEGGRSVFVFPGQGTQWAGMALGLWAES
AVFAESMARCEAAFAGLVDWRLADVLGDRSALERVDVVQPASFAVMVSLAELWRSLGVVP
DAVVGHSQGEIAAAVVAGGLSLEDGARVVVLRARLIGRELAGHGGMASVALPVAVVEERL
AAWAGRLGVAVVNAPSATVVAGDVDAVAEFVTACEVEGVRARVLPVDYASHSAHVEELRA
ELEQILAGIDPVAGETPLYSTVEAGVVDTASMDAGYWFRNLRRPVRFQETVERLLADGFR
VFVECGAHPVLTGAVQETAESTGRQVCAVGSLRRDEGGLRRFLTSAAEAFVQGVEVSWPV
LFDGTGARTVDLPTYPFQRRRYWLESRPPAAVVPSGVQDGLSYEVVWKSLPVRESSRLDG
RWLLVVPETLDADGTRIAHDLQHALTTHGATVHTLALDPSAAHFDGLFDGILQEETDVTG
IFSLLGLASGPHPDHGEVELAGAASLTLMRQAQRDGFRAPVWAVTRGAVSVVPGEVPETA
GAQLWALGRVAGLELPDRWGGLIDLPADADARTAGLAVRALAAGIADGEDQLAVRPSGAY
GRRLVRATARRGRKDWRPQGTVLLAGHLDAVGEPLARWLLTGGADHVVLADPALTELPAT
LADLAQTVTTAAAPDLADRAVLAALVTEYVPATVVVVPPAAELAPLASISPADLAAAVTA
KSATAAHFDALLDGPHAPELVLISSVAGIWGGVRQGAYAVGAAHLDALAARRRARGLSAA
SVAWTPWAGSVTADGSAAESLRQYGIAPLEPQAALAELDRALNQQLHGGGGDAAVADIDW
ERFLASFTSVRPSVLFDELPEVRRLREAEAAAMADQAAARTGAPGGTELARSLRAKSLNA
QRTALLELVTAHVAAVLGESVPEAIDRSRAFKDIGFTSMTAMELRNRLKEATGLALPASL
VFDHPHPGALADHLREELLGEDGAAGADSAAEEPSATSPTVQDEPIAIIGMACRLPGDVG
TPDELWELLETGRDAMSDLPVNRGWDVAGLYDPDPDAAGRSYVREGGFLHDAGEFDAEFF
GISPREALAMDPQQRIVLELAWESFERAGLDPAGRRGSRTGVFMGTNGQHYMPLLQNGND
SFDGYLGTGNSASVMSGRISYTLGLEGPALTVDTACSSSLVALHLAVRALRNGECDLALA
GGATVMSTPEVLVEFSRQRAVSADGRCKAFSASADGFGPAEGAGVLLVERLSDAVRHGRR
VLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALADARLGVADVDVVEGHGTGTRLGDP
IEAQALLATYGQRDAGRPLRLGSLKSNVGHTQAAAGVAGVIKMVMAMRHGVLPKTLHVDE
VSPHVDWSAGAVSLLTEQEPWPEVGRPRRAAVSSFGLSGTNAHVVVEEAPVGEAGQAAGD
ARLAVVPVVVSGRSAGAVAELASRLNESIRSDRLVDVGLSSVVSRSVFEHRSVLLAGDSG
ELHTGLVAVGTGVPSPGVVSGVASVGGGRSVFVFPGQGTQWAGMALGLWAESSVFAESMA
RCEAAFEGLVDWSLADVLGDGSALERVDVVQPASFAVMVSLAELWRSLGVVPDAVVGHSQ
GEIAAAVVAGGLSLEDGARVVVLRARLIGRELAGRGGMASVALPVAVVEERLAGWAGRLG
VAVVNGPSATVVAGDVDAVAEFVTACEVEGVRARVLPVDYASHSAHVEDLKAELEEVLAG
IGPVTGGIPFYSTSEAAQIDTAGLDAGYWFGNLRRPVRFQETVERLLADGFRVFVECGAH
PVLTGAVQETAESTGRQVCAVGSLRRDEGGLRRFLTSAAEAFVQGVGVFWPALFDGTGAR
IVDLPTYPFQRRHYWYNDPARRTGDATSFGMAQAGHPLLDAGTELPESGEHLYTARLAAD
SHPWLLEHTLLGAPLLPGAAFVDLVLWAGGEVGCDLIEELTLTSPLLLSDSAALQLRLVV
GTADAEGRRTITVHSRPDGDPRTTRTPAASSETSPDAESDTEIRRDTSAWTKHAQATVAP
APDVPPSGVDAEGDAVRPAVEWSVAATESDAFQAEDFYASFAAHGYGYGPLFQGVRSGRQ
DGTDVYAEVALDHDRLPSAEQFGLHPALLDAAFQTMRLGSFFPDDGQARVPYTFRGIRLY
APGAARLRVRVSAVGADAVRVECADERGRLVCEIDALVVSTVSPDQLRPAGQDATQDMLH
RIEWPVLSPPTGSATSPAPPRWIVVGGEDEGLGLGGLRLDGPRLDGPGLAEALSEAGMGT
ERHRNLADALSAVRTPVDTAGSAAAAGTTSLIAVPVPQSPTMDAGAVRHAVHRALELVQG
WVAADEAAEEGGSDGAAADRRLVLVTSGAVSTGDADPLRDPVAAAVWGLIKSAQSEQPGR
IVLVDLDEGAVDGAALAAAISTGEPQLALRDGDVHVPRLAPLSVRDSQTLLPPAGTRAWH
LVGAGTGTLSDLALVPAQTDTVALAPGQVRIAVRAAGLNFRDTLIALGMYPGEGVMGAEG
AGVITEVGPDVVSLAVGDRVLGMWTDGFGPYVVADHRMVAPMPRDWSYAEAASVPAVFLS
AYYGLRHLAGLRAGQSVLVHAAAGGVGMAAVQLARHFGAEVFGTAGTAKWDALRAQGLDD
RHIAGSRTLDFADRFLDATEGRGVDVVLNSLAGDFVDASLRLLPRGGRFVELGKADVRDA
AQVAADRPGTVYRAFELMEAGPELIGRMLNELLELFESGALRLLPVTPYDIRRAPDAFRT
LSQAGHVGKLVLTMPPAFEPHGTVLITGGTGNLGGTLARHLVTEHGVRHLLLAGRRGPEA
EGAAELVRELHDLGASVTVAACDVADRAALRKLLGGIPPERPLTGVVHAAGVLDDGVVTS
LTPDRVDGVLRPKVDAALNLHEAALDPELGLDITAFVLFSSVAALLGGSGQGSYAAANGF
LDGLAQYRRGRSLPALSLGWGLAGSGRMTSHLDSRALLRRMARGGVLPLSPAESMALFDA
AQGFDEALQVPARFHTAALGADGNVPPLFNGLIRGGTAHAEARRRTVGASPAGGPAGGEP
VNLADRLSGLTEDEQRALLLDTVRTHAALVLGHTGTDGIQADRAFKDLGFDSLTAVEMRN
RLTAATGLHLAATLVFDHPAPADLAEHLRSRLVPEGTDVPPLLAELGRLETAFKKLTTAD
LASVVPDDIARDEIAVRLAALGSLWNGLHGNGLSGDAAQKHGDSIVEDIDSADDDEIFAF
LDESFGDS
selected fasta
>polyketide synthase [polyketide synthase subunit]
ATGTCTTCCACATCGCCCGCCACCAACGAAGAGAAGCTCCGCGACTACCTCCGCCGCGCC
ATGACCGACCTGCACGAGGCCCGCGAGCAGATCCGCCGGACCGAGTCGGCCAGGCACGAG
CCGATCGCGATCGTGGGGATGGGGTGCCGTCTGCCGGGTGGGGTGTCGTCGCCGGAGGGG
TTGTGGGATCTGGTGGCGTCGGGGGTGGATGCGGTTTCTCCGTTCCCCACGGATCGGGGT
TGGGATGTGGGGGGTCTGTTCGATCCGGAGCCGGGGGTGCCGGGGCGTTCGTATGTGCGT
GAGGGCGGGTTCCTTCATGAGGCGGGGGAGTTCGACGCGGGGTTCTTCGGTATCTCTCCG
CGTGAGGCGTTGGCGATGGATCCGCAGCAGCGGTTGCTGTTGGAGACGTCGTGGGAGGCG
TTGGAGCGGGCGGGCATCGATCCGCACACGCTCCGCGGCTCACGGACCGGCGTCTACGCC
GGAGTGATGTACCACGACTACGGCAGCACCGCGACCGTCTCCGTCGCCTCCGACGACGAG
ACCGCCGGATTCCTCGGCACGGGGACGTCCGGGAGTGTGGCTTCGGGTCGTATCTCGTAT
GTGCTGGGGCTGGAGGGGCCGGCGGTGACGGTGGACACGGCGTGTTCGTCGTCGTTGGTG
GCGCTGCATCTGGCGGTGCGGGCGCTGCGGAGTGGTGAGTGTGACCTTGCTCTTGCGGGT
GGGGTGACGGTGATGGCGGAGCCGGGTGTGTTCGTGGAGTTCTCGCGGCAGCGGGGGTTG
GCTGCGGACGGGCGGTGCAAGGCGTTCGCGGCTGCTGCCGATGGCACGGGCTGGGCCGAG
GGTGTGGGCGTGCTGGCGGTGGAGCGGTTGTCGGATGCGGTGCGTCACGGGCGCCGGGTC
CTGGCGGTCGTGCGTGGTTCCGCGGTCAACCAGGACGGTGCGAGCAATGGGTTGACGGCT
CCGAACGGTCCGTCGCAGCAGCGGGTGATTCGTCAGGCGTTGGCGGATGCGCGGTTGGGT
GTGGCTGATGTGGATGTGGTGGAGGGGCATGGGACGGGGACGCGTCTGGGTGATCCGATC
GAGGCGCAGGCGTTGTTGGCGACGTATGGGCAGCGGGATGCGGGTCGGGCTTTGCGGCTT
GGTTCGCTGAAGTCGAACGTGGGGCATACGCAGGCGGCTGCCGGTGTGGCGGGCGTGATC
AAGATGGTCATGGCGATGCGGCACGGTGTCCTGCCGAAGACGCTGCACGTGGATGAGCCG
ACGGCGGAGGTGGACTGGTCGGCGGGCGCGGTGTCCCTGCTGAGGGAGCAGGAGGCGTGG
CCTGAGGTGGGGCGTCTGCGTAGGGCTGCGGTGTCTTCGTTCGGTGTGAGTGGGACGAAC
GCGCATGTGGTGGTGGAGGAGGCACCTGCTTCGGAGGCGCCGGTCGCGGGGGAGCCGGTG
GAGCCGGTGGAGCCGGGGGCTGTGGGGCTTCTTCCGGTGGTGCCGGTGGTGGTGTCGGGT
CGTTCTGCGGGTGCGGTGGCGGAGCTGGCCTCCCGCTTGAACGAGTCGGTTCGTTCGGAT
CGGTTGGTGGATGTGGGGTTGTCGTCGGTGGTGTCGCGGTCGGTGTTCGAGCACCGGTCC
GTGGTTCTGGCGGAGGACTCTGCCGAGCTGCATACCGGTCTGGTTGCTGTCGGGACTGGG
GTGCCGTCGCCTGGCGTGGTGTCGGGTGTGGCGTCGGTCGAGGGTGGCCGGTCGGTGTTC
GTGTTCCCTGGTCAGGGGACGCAGTGGGCGGGGATGGCGCTCGGGTTGTGGGCGGAGTCG
GCGGTGTTCGCGGAGTCGATGGCGCGGTGTGAGGCGGCGTTCGCCGGGTTGGTGGACTGG
CGTCTGGCGGATGTGCTGGGTGACAGGTCTGCGTTGGAGCGGGTCGATGTGGTGCAGCCG
GCGTCGTTCGCGGTGATGGTGTCGCTGGCCGAGCTGTGGCGGTCGCTGGGTGTGGTGCCC
GATGCGGTGGTGGGGCATTCGCAGGGGGAGATCGCTGCTGCGGTGGTGGCGGGTGGTCTC
TCGCTGGAGGACGGCGCGCGTGTGGTGGTGTTGCGTGCGCGGTTGATAGGCCGTGAGCTG
GCCGGGCACGGTGGGATGGCGTCGGTGGCGCTGCCGGTCGCGGTGGTGGAGGAGCGTCTG
GCGGCGTGGGCGGGGCGTCTGGGTGTGGCGGTGGTCAACGCACCCTCCGCCACGGTCGTC
GCGGGTGATGTGGACGCGGTGGCGGAGTTTGTGACCGCGTGCGAGGTGGAGGGGGTTCGG
GCGCGTGTTCTGCCGGTGGACTACGCCTCGCACTCGGCGCACGTGGAGGAGCTGAGGGCC
GAGCTTGAACAGATTCTGGCCGGCATCGACCCGGTGGCCGGTGAGACCCCCCTGTACTCC
ACGGTGGAGGCGGGTGTCGTGGATACGGCGTCGATGGATGCGGGGTACTGGTTCAGGAAT
CTGCGTCGGCCGGTTCGTTTCCAGGAGACGGTCGAGCGGTTGCTGGCGGATGGTTTCCGG
GTGTTCGTGGAGTGCGGCGCGCATCCGGTGCTGACGGGGGCGGTGCAGGAGACCGCGGAA
TCCACCGGTCGCCAGGTGTGTGCGGTCGGATCCCTGCGTCGTGACGAGGGTGGTCTGCGA
CGCTTCCTGACCTCTGCGGCGGAGGCGTTCGTCCAGGGGGTGGAGGTGTCCTGGCCGGTG
CTGTTCGATGGCACCGGCGCCCGCACGGTCGACCTGCCCACCTACCCCTTCCAGCGTCGG
CGTTACTGGCTGGAGTCACGTCCTCCTGCGGCGGTTGTTCCGTCGGGGGTCCAGGACGGA
TTGTCGTATGAGGTGGTGTGGAAGAGCCTGCCGGTACGGGAGTCGTCGCGTCTTGACGGC
CGGTGGCTGCTCGTCGTGCCCGAAACCCTGGACGCCGACGGCACGCGGATCGCCCACGAC
CTCCAGCACGCCCTCACCACCCACGGCGCCACCGTGCACACTCTTGCTCTTGACCCCAGC
GCGGCGCACTTCGACGGTCTCTTTGACGGGATACTCCAGGAAGAAACAGATGTCACGGGC
ATCTTCTCTCTCCTCGGACTGGCATCGGGCCCGCACCCGGATCACGGCGAGGTGGAGCTC
GCGGGAGCCGCGTCGCTGACGTTGATGCGCCAAGCCCAGCGAGACGGCTTCCGTGCTCCG
GTGTGGGCGGTGACGCGGGGTGCGGTGTCCGTGGTGCCTGGTGAGGTGCCGGAGACCGCG
GGTGCGCAACTGTGGGCGCTCGGCCGGGTCGCCGGTCTCGAACTCCCCGACCGTTGGGGT
GGTCTGATCGATCTCCCGGCGGATGCCGATGCGCGTACGGCGGGGCTTGCGGTGCGGGCC
CTGGCCGCCGGGATCGCCGATGGTGAGGACCAGCTGGCGGTGCGCCCCTCAGGTGCCTAC
GGCCGGCGCCTCGTACGAGCCACCGCGCGCCGGGGACGGAAGGACTGGCGCCCGCAGGGT
ACGGTGCTGCTCGCCGGGCACCTCGACGCCGTCGGTGAACCACTGGCCCGATGGCTGCTC
ACCGGCGGCGCGGACCACGTCGTCCTTGCGGATCCCGCCCTGACCGAACTCCCGGCCACC
CTCGCGGATCTGGCCCAGACCGTGACGACCGCTGCGGCACCCGACCTTGCCGACCGTGCA
GTCCTCGCCGCCCTGGTCACCGAGTACGTACCCGCCACCGTGGTCGTCGTTCCGCCCGCG
GCGGAGCTCGCTCCGCTGGCGAGTATCAGCCCGGCCGACCTCGCGGCGGCCGTCACCGCC
AAGTCCGCGACCGCGGCGCACTTCGACGCGCTGCTCGACGGACCCCACGCACCGGAGCTG
GTGCTGATCTCCTCGGTCGCGGGGATCTGGGGTGGTGTCCGGCAGGGTGCGTACGCCGTC
GGTGCCGCTCACCTCGATGCCCTGGCCGCCCGCCGCAGGGCCCGCGGTCTGTCGGCGGCC
TCCGTCGCGTGGACGCCCTGGGCGGGTTCCGTCACCGCGGACGGCTCCGCCGCCGAGTCG
CTGCGGCAGTACGGCATCGCTCCGCTGGAGCCGCAGGCGGCGCTCGCGGAGCTGGACCGG
GCGCTGAACCAGCAGCTGCACGGCGGCGGGGGCGACGCGGCGGTGGCCGACATCGACTGG
GAGCGGTTCCTCGCGTCGTTCACCTCCGTACGTCCCAGCGTTCTCTTCGACGAGCTGCCC
GAGGTACGCCGTCTCCGCGAGGCGGAGGCGGCGGCCATGGCGGACCAGGCCGCCGCCCGG
ACGGGAGCGCCCGGCGGAACGGAGCTGGCGCGCTCTCTGCGGGCCAAGTCCCTGAACGCC
CAGCGAACTGCGCTCCTGGAATTGGTCACTGCCCACGTGGCGGCCGTGCTGGGAGAGAGC
GTTCCCGAGGCGATCGACCGGAGCCGGGCGTTCAAGGACATCGGCTTCACCTCCATGACC
GCGATGGAACTGCGCAACCGGCTCAAGGAGGCCACCGGGCTCGCCCTTCCTGCCTCCCTC
GTCTTCGACCACCCCCACCCCGGCGCACTCGCCGACCACCTGCGCGAGGAACTCCTGGGC
GAGGACGGTGCGGCGGGCGCCGACTCCGCGGCGGAGGAACCGAGCGCTACCTCTCCGACG
GTCCAGGACGAGCCGATCGCCATCATCGGCATGGCCTGCCGCCTCCCTGGTGACGTCGGA
ACACCCGACGAACTCTGGGAGCTGCTGGAAACCGGCCGCGACGCGATGTCGGACCTGCCC
GTCAACCGCGGGTGGGACGTGGCGGGGCTCTACGACCCGGATCCAGACGCGGCGGGGCGT
TCCTACGTCCGGGAGGGCGGGTTCCTCCACGACGCGGGGGAGTTCGACGCGGAGTTCTTC
GGCATCTCGCCGCGTGAGGCGCTGGCGATGGACCCGCAGCAGCGCATCGTCCTCGAACTC
GCCTGGGAATCGTTCGAACGTGCGGGCCTGGACCCGGCCGGCCGCCGCGGCAGCCGTACC
GGCGTGTTCATGGGAACCAACGGCCAGCACTACATGCCGCTGCTGCAGAACGGCAACGAC
AGCTTCGACGGCTACCTCGGCACCGGGAACTCGGCCAGTGTCATGTCGGGCCGCATCTCG
TACACCCTCGGCTTGGAGGGGCCGGCGCTGACGGTGGACACGGCGTGTTCGTCGTCGCTG
GTCGCGCTGCATCTGGCGGTGCGGGCGCTGCGCAACGGTGAGTGCGACCTCGCCCTCGCC
GGCGGCGCGACCGTGATGTCGACGCCGGAAGTCCTGGTGGAGTTCTCCCGGCAGCGTGCA
GTCTCCGCAGACGGTCGCTGCAAGGCGTTCTCCGCCTCGGCCGACGGCTTCGGACCGGCC
GAGGGTGCGGGCGTGTTGCTCGTCGAGCGGTTGTCGGATGCGGTGCGTCATGGGCGTCGG
GTGTTGGCGGTCGTGCGTGGTTCGGCGGTGAATCAGGACGGTGCGAGTAATGGGTTGACG
GCTCCGAACGGTCCGTCGCAGCAGCGGGTGATTCGTCAGGCGTTGGCGGATGCGCGGTTG
GGTGTGGCTGATGTGGATGTGGTGGAGGGGCATGGGACGGGGACGCGTCTGGGTGATCCG
ATCGAGGCGCAGGCGTTGTTGGCGACGTATGGGCAGCGGGATGCGGGTCGGCCGTTGCGG
CTTGGTTCGTTGAAGTCGAACGTGGGGCATACGCAGGCGGCTGCCGGTGTGGCGGGCGTG
ATCAAGATGGTCATGGCGATGCGGCACGGTGTCCTGCCGAAGACGCTGCACGTCGATGAG
GTCTCTCCGCACGTCGACTGGTCGGCGGGTGCGGTGTCCCTGCTGACGGAGCAGGAGCCG
TGGCCGGAGGTGGGGCGCCCTCGCAGGGCTGCGGTCTCTTCGTTCGGGCTCAGCGGGACG
AATGCGCATGTGGTGGTCGAGGAGGCGCCGGTCGGGGAGGCGGGGCAGGCCGCCGGGGAT
GCTCGGTTGGCTGTGGTGCCGGTGGTGGTGTCGGGCCGGTCTGCGGGTGCGGTTGCTGAA
CTGGCCTCCCGCTTGAACGAGTCGATTCGTTCGGATCGGTTGGTGGATGTGGGGTTGTCG
TCGGTGGTGTCGCGGTCGGTGTTCGAGCACCGGTCCGTGCTACTGGCGGGGGACTCTGGC
GAGCTGCATACCGGTCTGGTTGCTGTCGGGACTGGTGTGCCGTCGCCTGGTGTGGTGTCG
GGTGTGGCGTCGGTCGGGGGTGGCCGGTCGGTGTTCGTGTTCCCTGGTCAGGGGACGCAG
TGGGCGGGGATGGCGCTCGGGTTGTGGGCGGAGTCGTCGGTGTTCGCGGAGTCGATGGCG
CGGTGTGAGGCGGCGTTCGAGGGGTTGGTGGACTGGAGTCTGGCGGATGTGCTGGGTGAC
GGGTCCGCGTTGGAGCGGGTCGATGTGGTGCAGCCGGCGTCGTTCGCGGTGATGGTGTCG
CTTGCTGAGCTGTGGCGGTCGTTGGGTGTGGTGCCGGATGCGGTGGTGGGGCATTCGCAG
GGGGAGATCGCTGCTGCGGTGGTGGCGGGTGGTCTGTCGTTGGAAGACGGGGCGCGTGTG
GTGGTGTTGCGTGCGCGGTTGATCGGCCGTGAGCTGGCCGGGCGCGGTGGGATGGCGTCG
GTGGCGCTGCCGGTCGCGGTGGTGGAGGAGCGTCTGGCGGGGTGGGCGGGGCGTCTGGGT
GTGGCGGTGGTCAACGGACCGTCCGCCACGGTCGTCGCGGGTGATGTGGATGCGGTGGCG
GAGTTTGTGACCGCGTGCGAGGTGGAGGGGGTTCGGGCGCGTGTTCTGCCGGTGGACTAC
GCCTCGCACTCGGCGCACGTGGAGGACCTGAAGGCCGAGCTTGAAGAGGTGCTGGCCGGC
ATCGGCCCGGTGACCGGTGGGATCCCGTTCTATTCGACGTCCGAAGCCGCGCAGATCGAC
ACGGCTGGTCTGGACGCGGGGTACTGGTTCGGGAATCTGCGTCGGCCGGTGCGGTTCCAG
GAGACGGTCGAGCGGTTGTTGGCGGATGGTTTCCGGGTGTTCGTGGAGTGTGGTGCGCAT
CCGGTGCTGACGGGGGCGGTGCAGGAGACCGCGGAATCCACCGGTCGCCAGGTGTGTGCG
GTCGGATCCCTGCGTCGTGACGAGGGAGGTCTGCGCCGCTTCCTCACCTCTGCGGCGGAG
GCGTTCGTCCAGGGGGTCGGGGTGTTCTGGCCGGCACTGTTCGACGGCACCGGCGCCCGT
ATCGTCGACCTGCCCACCTACCCCTTCCAACGACGGCACTACTGGTACAACGACCCTGCC
CGCCGCACGGGCGATGCCACCTCCTTCGGTATGGCGCAGGCCGGTCATCCCTTGCTCGAT
GCCGGTACGGAGCTCCCTGAATCAGGCGAGCACCTCTACACCGCTCGGCTCGCCGCCGAC
TCGCATCCTTGGCTGCTGGAACACACCCTGCTGGGTGCGCCGTTGCTGCCCGGTGCGGCG
TTCGTCGACCTCGTCCTGTGGGCCGGCGGGGAGGTCGGATGCGACCTGATCGAAGAGCTG
ACGCTGACCTCGCCGCTGCTGTTGTCCGACAGCGCTGCCCTTCAACTGCGGCTGGTCGTG
GGCACGGCGGACGCCGAGGGACGTCGTACGATCACCGTCCACTCGCGGCCGGACGGAGAC
CCGCGTACGACGCGCACACCTGCGGCATCGTCCGAGACCAGCCCGGACGCGGAGTCGGAC
ACGGAGATCCGTAGGGACACGTCCGCCTGGACGAAGCACGCTCAGGCGACGGTCGCCCCC
GCCCCTGACGTCCCCCCTTCCGGGGTGGACGCGGAAGGGGACGCCGTTCGCCCCGCAGTG
GAATGGAGCGTGGCGGCGACGGAGTCGGATGCCTTCCAGGCCGAGGACTTCTACGCGTCC
TTCGCCGCACACGGCTATGGCTACGGCCCGCTGTTCCAGGGCGTACGGTCAGGCCGTCAG
GACGGGACCGACGTCTACGCCGAAGTCGCCCTGGATCACGACCGCTTGCCGTCTGCCGAG
CAGTTCGGCCTGCACCCCGCGCTGCTCGACGCGGCGTTCCAGACGATGCGTCTGGGATCG
TTCTTCCCCGACGACGGACAGGCACGTGTGCCGTACACCTTCCGGGGGATTCGTCTCTAC
GCCCCGGGAGCCGCGCGCCTGCGGGTCCGTGTCTCGGCGGTCGGGGCCGATGCCGTACGC
GTGGAGTGCGCCGATGAGCGGGGGCGGCTCGTCTGTGAGATCGACGCCCTCGTCGTCAGC
ACGGTCTCCCCGGACCAGTTGCGGCCGGCCGGACAGGACGCGACCCAGGACATGCTGCAC
CGGATCGAGTGGCCCGTCCTCTCCCCGCCGACCGGCAGCGCCACCTCCCCTGCTCCGCCC
CGCTGGATCGTGGTCGGGGGCGAGGACGAGGGCCTCGGGCTCGGGGGCCTTCGACTCGAC
GGTCCGAGGCTTGACGGTCCCGGGCTTGCGGAAGCGCTGTCCGAAGCCGGTATGGGGACC
GAGCGTCACCGGAACCTGGCCGACGCGCTGTCGGCCGTACGGACGCCGGTGGACACGGCA
GGCTCCGCTGCCGCCGCCGGCACGACCTCCCTCATAGCCGTCCCCGTACCGCAGTCGCCC
ACCATGGACGCCGGTGCCGTGCGCCACGCCGTCCACCGAGCCCTGGAGCTGGTGCAGGGC
TGGGTGGCGGCGGACGAGGCGGCGGAAGAGGGCGGGAGCGACGGTGCCGCGGCCGACCGG
CGGCTGGTGCTGGTCACGAGCGGAGCGGTGTCCACGGGTGACGCCGACCCGCTGCGCGAC
CCGGTGGCCGCGGCCGTCTGGGGTCTGATCAAGTCCGCCCAGTCGGAGCAGCCCGGCCGC
ATCGTCCTCGTTGACCTCGACGAGGGAGCCGTGGACGGGGCGGCCTTGGCAGCCGCGATC
TCGACCGGCGAACCACAACTCGCCCTGCGCGACGGCGATGTGCACGTGCCCAGGCTGGCA
CCCCTGTCCGTGCGGGACTCGCAGACGCTGCTGCCGCCCGCCGGTACGCGCGCCTGGCAT
CTGGTCGGCGCCGGCACCGGAACCCTTTCGGACCTCGCGCTCGTACCGGCGCAGACCGAC
ACCGTCGCGCTCGCACCTGGGCAGGTGCGGATCGCGGTGCGAGCCGCCGGACTCAACTTC
CGGGACACGCTCATCGCGCTCGGTATGTATCCGGGCGAGGGCGTGATGGGCGCCGAGGGC
GCCGGAGTGATCACCGAGGTCGGCCCGGACGTGGTGAGCCTCGCCGTCGGGGACCGCGTC
CTGGGCATGTGGACCGACGGGTTCGGGCCGTACGTCGTGGCCGACCACCGCATGGTGGCC
CCGATGCCGCGCGACTGGTCCTACGCGGAGGCCGCTTCGGTACCCGCCGTCTTCCTCAGT
GCCTACTACGGACTCAGGCACCTGGCCGGTCTGCGCGCCGGCCAGTCGGTGCTGGTGCAC
GCGGCGGCGGGCGGTGTGGGCATGGCTGCCGTCCAACTCGCCCGGCACTTCGGGGCCGAG
GTCTTCGGCACGGCCGGCACGGCCAAATGGGACGCACTGCGGGCACAGGGCCTGGACGAC
CGGCACATCGCCGGTTCACGGACGCTGGACTTCGCGGACCGGTTTCTCGACGCGACCGAG
GGGCGCGGCGTGGACGTCGTCCTGAACTCGCTGGCGGGCGACTTCGTCGACGCCTCCCTG
CGACTGCTGCCGCGCGGAGGGCGGTTCGTGGAACTGGGCAAGGCGGACGTACGCGACGCC
GCGCAGGTCGCCGCCGACCGGCCGGGAACCGTCTACCGGGCCTTCGAGCTGATGGAGGCC
GGGCCGGAGCTGATCGGCCGCATGCTGAACGAACTGCTGGAACTGTTCGAGTCCGGGGCG
CTGCGCCTGCTGCCCGTCACCCCGTACGACATCCGGCGGGCACCCGACGCCTTCCGCACG
CTCAGCCAGGCCGGTCACGTCGGCAAACTGGTCCTGACGATGCCACCGGCCTTCGAACCC
CACGGCACGGTCCTGATCACCGGCGGCACCGGGAACCTGGGCGGAACACTCGCCCGCCAT
CTCGTGACCGAACACGGAGTGCGCCACCTGCTCCTGGCCGGACGTAGGGGGCCCGAGGCC
GAAGGCGCCGCCGAACTCGTACGGGAACTGCACGACCTGGGCGCCTCCGTCACGGTCGCC
GCCTGTGACGTGGCCGACCGAGCGGCGCTCCGGAAACTCCTCGGCGGCATACCGCCGGAG
CGCCCGCTCACCGGAGTCGTCCACGCGGCGGGCGTTCTCGACGACGGCGTGGTCACGTCA
TTGACCCCGGACAGGGTCGACGGCGTCCTGCGGCCCAAGGTGGATGCCGCTCTCAACCTC
CACGAAGCGGCCCTCGATCCCGAACTCGGTCTCGACATCACCGCGTTCGTCCTGTTCTCG
TCCGTCGCTGCCCTGCTCGGCGGCTCGGGTCAGGGAAGCTACGCCGCCGCCAACGGCTTC
CTCGACGGACTCGCCCAGTACCGGCGTGGCCGCTCGCTGCCCGCGCTCTCCCTCGGCTGG
GGCCTGGCCGGGAGCGGCCGGATGACATCCCACCTGGACAGCCGGGCCCTGCTCCGGCGC
ATGGCCAGGGGCGGTGTCCTGCCGCTGTCCCCGGCGGAGAGCATGGCACTGTTCGACGCG
GCCCAGGGCTTCGACGAGGCGCTCCAGGTGCCGGCGCGCTTCCACACCGCCGCACTGGGC
GCCGACGGCAACGTCCCGCCGCTCTTCAACGGACTGATCCGGGGCGGGACGGCGCATGCC
GAGGCCCGGCGCAGGACGGTCGGCGCGTCGCCCGCGGGTGGTCCTGCCGGAGGCGAGCCG
GTGAACCTCGCCGACCGGCTGTCCGGACTGACGGAGGACGAACAGCGGGCGCTGCTCCTC
GACACGGTGCGCACGCACGCGGCTCTCGTCCTGGGCCACACGGGCACGGACGGCATCCAG
GCCGACCGGGCGTTCAAGGACCTGGGATTCGACTCGCTGACGGCCGTCGAGATGCGCAAC
CGGCTCACCGCCGCCACGGGGCTGCACCTCGCGGCGACGCTGGTCTTCGACCACCCCGCT
CCGGCGGACCTCGCCGAGCACCTCCGCTCTCGACTCGTCCCCGAGGGGACGGACGTACCG
CCGCTCCTCGCGGAACTCGGTCGGCTCGAAACGGCGTTCAAGAAGCTGACCACCGCGGAC
CTCGCCTCGGTCGTGCCCGACGACATCGCCCGCGACGAGATCGCCGTACGTCTCGCCGCC
CTCGGTTCCCTGTGGAACGGGCTCCATGGCAACGGCCTCAGCGGAGACGCGGCGCAGAAG
CACGGCGACTCGATCGTCGAGGACATCGACTCCGCCGACGACGACGAGATCTTCGCCTTC
CTCGACGAGAGCTTCGGCGACTCCTGA
[4] KS40..418
[4] AT579..896
[4] methylmalonyl-CoA768..772
[4] kr1160..1330
[4] ACP1445..1515
[5] KS1543..1919
[5] AT2071..2387
[5] methylmalonyl-CoA2260..2264
[5] DH2436..2635
[5] ER3007..3312
[5] KR3322..3503
[5] ACP3619..3689
[4] KS118..1254
[4] AT1735..2688
[4] methylmalonyl-CoA2302..2316
[4] kr3478..3990
[4] ACP4333..4545
[5] KS4627..5757
[5] AT6211..7161
[5] methylmalonyl-CoA6778..6792
[5] DH7306..7905
[5] ER9019..9936
[5] KR9964..10509
[5] ACP10855..11067

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR001227 Acyl transferase domain (Domain)
[573-699] G3DSA:3.40.366.10 [768-885] G3DSA:3.40.366.10 [2067-2191] G3DSA:3.40.366.10 [2260-2377] G3DSA:3.40.366.10
G3DSA:3.40.366.10   Ac_transferase_reg
IPR002198 Short-chain dehydrogenase/reductase SDR (Family)
[3322-3490] 2.19999999999997e-59 PF00106
PF00106   adh_short
IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site (Conserved_site)
[3134-3155] PS01162
PS01162   QOR_ZETA_CRYSTAL
IPR006162 Phosphopantetheine attachment site (PTM)
[3647-3662] PS00012
PS00012   PHOSPHOPANTETHEINE
IPR009081 Acyl carrier protein-like (Domain)
[1449-1514] 2.8e-10 PF00550 [3622-3688] 3.7e-10 PF00550
PF00550   PP-binding
[1438-1560] 7.19999557654549e-25 SSF47336 [3610-3696] 5.10001002358244e-22 SSF47336
SSF47336   ACP_like
[1442-1518] 2.89999999999999e-42 G3DSA:1.10.1200.10 [3619-3692] 2.89999999999999e-42 G3DSA:1.10.1200.10
G3DSA:1.10.1200.10   ACP_like
[1445-1515] PS50075 [3619-3689] PS50075
PS50075   ACP_DOMAIN
IPR011032 GroES-like (Domain)
[2993-3141] 1.20000117458134e-32 SSF50129
SSF50129   GroES_like
IPR013149 Alcohol dehydrogenase, C-terminal (Domain)
[3145-3236] 4.2e-17 PF00107
PF00107   ADH_zinc_N
IPR013154 Alcohol dehydrogenase GroES-like (Domain)
[3026-3084] 4.5e-08 PF08240
PF08240   ADH_N
IPR013968 Polyketide synthase, KR (Domain)
[1160-1329] 1.9e-27 PF08659
PF08659   KR
IPR014030 Beta-ketoacyl synthase, N-terminal (Domain)
[40-293] 7.99999999999993e-100 PF00109 [1543-1794] 7.20000000000003e-98 PF00109
PF00109   ketoacyl-synt
IPR014031 Beta-ketoacyl synthase, C-terminal (Domain)
[301-418] 1.09999999999999e-46 PF02801 [1802-1919] 1.70000000000001e-47 PF02801
PF02801   Ketoacyl-synt_C
IPR014043 Acyl transferase (Domain)
[579-896] 5.30000000000001e-102 PF00698 [2071-2387] 9.69999999999989e-103 PF00698
PF00698   Acyl_transf_1
IPR015083 Polyketide synthase, docking (Domain)
[8-32] 2.4e-10 PF08990
PF08990   Docking
IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase (Domain)
[577-877] 4.89996723796399e-65 SSF52151 [2069-2369] 1.20000117458134e-64 SSF52151
SSF52151   Acyl_Trfase/lysoPlipase
IPR016036 Malonyl-CoA ACP transacylase, ACP-binding (Domain)
[702-767] 1.60000240695997e-17 SSF55048 [2194-2259] 4.30000170645867e-18 SSF55048
SSF55048   Malonyl_transacylase_ACP-bd
IPR016038 Thiolase-like, subgroup (Domain)
[42-305] G3DSA:3.40.47.10 [306-470] 3.30000000000002e-126 G3DSA:3.40.47.10 [1546-1806] G3DSA:3.40.47.10 [1807-1970] 3.30000000000002e-126 G3DSA:3.40.47.10
G3DSA:3.40.47.10   Thiolase-like_subgr
IPR016039 Thiolase-like (Domain)
[32-470] 2.19999900980707e-102 SSF53901 [1536-1917] 2.89997807423186e-103 SSF53901
SSF53901   Thiolase-like
IPR016040 NAD(P)-binding domain (Domain)
[1161-1336] 3.09999999999998e-45 G3DSA:3.40.50.720 [3097-3285] 1.29999999999998e-48 G3DSA:3.40.50.720 [3323-3532] 3.09999999999998e-45 G3DSA:3.40.50.720
G3DSA:3.40.50.720   NAD(P)-bd
IPR018201 Beta-ketoacyl synthase, active site (Active_site)
[206-222] PS00606 [1707-1723] PS00606
PS00606   B_KETOACYL_SYNTHASE
IPR020801 Polyketide synthase, acyl transferase domain (Domain)
[581-876] 1.3000049540733e-114 SM00827 [2073-2368] 2.1000026783403e-114 SM00827
SM00827   PKS_AT
IPR020806 Polyketide synthase, phosphopantetheine-binding domain (Domain)
[1446-1518] 2.10000267834031e-31 SM00823 [3620-3692] 1e-30 SM00823
SM00823   PKS_PP
IPR020807 Polyketide synthase, dehydratase domain (Domain)
[2436-2635] 1.90000694315261e-65 SM00826
SM00826   PKS_DH
IPR020841 Polyketide synthase, beta-ketoacyl synthase domain (Domain)
[42-470] SM00825 [1546-1971] SM00825
SM00825   PKS_KS
IPR020842 Polyketide synthase/Fatty acid synthase, KR (Domain)
[1160-1330] 4.19999771339581e-12 SM00822 [3322-3503] 1.60000240695997e-54 SM00822
SM00822   PKS_KR
IPR020843 Polyketide synthase, enoylreductase (Domain)
[3007-3312] SM00829
SM00829   PKS_ER
SignalP No significant hit
TMHMM No significant hit
Chalc_00220 Chalc_00220   Chalc_00240 Chalc_00240
Page top