BLAST table : Chalc_00230

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q5SFB2_STRBI
(Q5SFB2)		 
[query] 1 - 3788 (3788)
[subject] 1 - 3788 (3788)
 0.0 7400   100% Polyketide synthase subunit chmGIII Streptomyces bikiniensis
2
 B4VEL0_9ACTO
(B4VEL0)		 
[query] 1 - 3788 (3788)
[subject] 6 - 3761 (3761)
 0.0 6043   87% Polyketide synthase subunit SSAG_06220 Streptomyces sp. Mg1
3
 Q8KPW3_9ACTO
(Q8KPW3)		 
[query] 21 - 3788 (3788)
[subject] 1 - 3734 (3734)
 0.0 5997   87% Putative type I polyketide synthase gerSIII Streptomyces sp. KCTC 0041BP
4
 A9YLB4_9ACTO
(A9YLB4)		 
[query] 2 - 3785 (3788)
[subject] 8 - 3850 (3850)
 0.0 3617   56% AngAIII angAIII Streptomyces eurythermus
5
 O33956_STRFR
(O33956)		 
[query] 2 - 3785 (3788)
[subject] 5 - 3729 (3729)
 0.0 3563   56% Tylactone synthase modules 4 & 5 tylG Streptomyces fradiae
Streptomyces roseoflavus
6
 Q5SFB4_STRBI
(Q5SFB4)		 Jump to Chalc_00210 
[query] 40 - 3012 (3788)
[subject] 1063 - 3986 (4441)
(9 hsp)		 0.0 3524   67% Polyketide synthase subunit chmGI Streptomyces bikiniensis
7
 Q83WE8_MICGR
(Q83WE8)		 
[query] 7 - 3788 (3788)
[subject] 3 - 3649 (3649)
 0.0 3297   55% Protomycinolide IV synthase 3 mycAIII Micromonospora griseorubida
8
 Q8KPW5_9ACTO
(Q8KPW5)		 
[query] 5 - 3012 (3788)
[subject] 978 - 3929 (4387)
(8 hsp)		 0.0 3293   64% Putative type I polyketide synthase gerSI Streptomyces sp. KCTC 0041BP
9
 Q9ZGI4_9ACTO
(Q9ZGI4)		 Jump to Pikro_00040 
[query] 9 - 3788 (3788)
[subject] 5 - 3737 (3739)
 0.0 3210   53% Type I polyketide synthase PikAII pikAII Streptomyces venezuelae
10
 B4VAJ6_9ACTO
(B4VAJ6)		 
[query] 5 - 2666 (3788)
[subject] 986 - 3604 (3605)
(6 hsp)		 0.0 3205   68% Polyketide synthase subunit SSAG_04835 Streptomyces sp. Mg1
11
 E0KRC7_STRVO
(E0KRC7)		 
[query] 40 - 3692 (3788)
[subject] 191 - 3753 (5559)
(9 hsp)		 0.0 3068   51% Beta-ketoacyl synthase StrviDRAFT_5204 Streptomyces violaceusniger Tu 4113
12
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 40 - 3692 (3788)
[subject] 1729 - 5297 (7102)
(12 hsp)		 0.0 3054   51% Polyketide synthase merB Streptomyces sp. NRRL 30748
13
 A0FCL2_STRVO
(A0FCL2)		 Jump to Merid_00030 
[query] 40 - 3692 (3788)
[subject] 1734 - 5373 (7178)
(13 hsp)		 0.0 3044   51% MerB merB Streptomyces violaceoniger
14
 A4F7P0_SACEN
(A4F7P0)		 
[query] 8 - 3786 (3788)
[subject] 2 - 3562 (3567)
 0.0 2823   48% EryAII Erythromycin polyketide synthase modules 3 and 4 eryAII
SACE_0723		 Saccharopolyspora erythraea (strain NRRL 23338)
15
 Q5UNP5_SACER
(Q5UNP5)		 
[query] 8 - 3786 (3788)
[subject] 2 - 3562 (3567)
 0.0 2823   48% EryAII eryAII Saccharopolyspora erythraea
Streptomyces erythraeus
16
 ERYA2_SACER
(Q03132)		 
[query] 8 - 3786 (3788)
[subject] 2 - 3562 (3567)
 0.0 2810   48% Erythronolide synthase, modules 3 and 4
6-deoxyerythronolide B synthase II
DEBS 2
ORF 2		 eryA Saccharopolyspora erythraea
Streptomyces erythraeus		 2.3.1.94
17
 Q9F829_9ACTO
(Q9F829)		 Jump to Megalo_00130 
[query] 8 - 3786 (3788)
[subject] 2 - 3557 (3562)
 0.0 2782   48% Megalomicin 6-deoxyerythronolide B synthase 2 megAII Micromonospora megalomicea subsp. nigra
18
 E0KRC6_STRVO
(E0KRC6)		 
[query] 30 - 3692 (3788)
[subject] 5909 - 9411 (11118)
(15 hsp)		 0.0 2748   48% Beta-ketoacyl synthase StrviDRAFT_5203 Streptomyces violaceusniger Tu 4113
19
 A0FCL3_STRVO
(A0FCL3)		 Jump to Merid_00040 
[query] 30 - 3692 (3788)
[subject] 5933 - 9538 (11604)
(15 hsp)		 0.0 2746   48% MerC merC Streptomyces violaceoniger
20
 C5HV14_STRAT
(C5HV14)		 Jump to Indano_00160 
[query] 45 - 3695 (3788)
[subject] 1094 - 4701 (4779)
(6 hsp)		 0.0 2745   48% Polyketide synthase idmL Streptomyces antibioticus
21
 Q83X70_STRRO
(Q83X70)		 
[query] 8 - 3787 (3788)
[subject] 2 - 3651 (3656)
 0.0 2738   47% Lankamycin synthase LkmAII lkmAII Streptomyces rochei
Streptomyces parvullus
22
 E8S0C2_MICSL
(E8S0C2)		 
[query] 9 - 3788 (3788)
[subject] 3 - 3743 (3743)
 0.0 2736   47% Beta-ketoacyl synthase ML5_5895 Micromonospora sp. (strain L5)
23
 D9T6W7_MICAI
(D9T6W7)		 
[query] 9 - 3788 (3788)
[subject] 3 - 3741 (3741)
 0.0 2734   47% Acyl transferase Micau_2467 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
24
 A0ACH1_STRAM
(A0ACH1)		 
[query] 8 - 3692 (3788)
[subject] 3 - 3570 (8154)
(9 hsp)		 0.0 2734   48% Putative polyketide synthase B SAMR0465 Streptomyces ambofaciens ATCC 23877
25
 Q0ILD4_9ACTO
(Q0ILD4)		 
[query] 40 - 3787 (3788)
[subject] 2479 - 6146 (6148)
(7 hsp)		 0.0 2724   48% NlmA1 nlmA1 Streptomyces nanchangensis
26
 D6C4C5_9ACTO
(D6C4C5)		 Jump to Meili_00790 
[query] 40 - 3788 (3788)
[subject] 578 - 4330 (4330)
(5 hsp)		 0.0 2721   46% Modular polyketide synthase meiA1 Streptomyces nanchangensis
27
 Q93HJ5_STRAW
(Q93HJ5)		 Jump to Oligo_00080 
[query] 40 - 3787 (3788)
[subject] 2467 - 6144 (6146)
(7 hsp)		 0.0 2720   48% Modular polyketide synthase olmA1
SAV2899
SAV_2899		 Streptomyces avermitilis
28
 D7C488_STRBB
(D7C488)		 
[query] 40 - 3788 (3788)
[subject] 587 - 4343 (4343)
(5 hsp)		 0.0 2718   46% Type I polyketide synthase milA1
SBI_00789		 Streptomyces bingchenggensis (strain BCW-1)
29
 Q53840_SORCE
(Q53840)		 Jump to Soraph_00080 
[query] 8 - 3700 (3788)
[subject] 2 - 3660 (8817)
(10 hsp)		 0.0 2627   45% Soraphen polyketide synthase B sorB Sorangium cellulosum
Polyangium cellulosum
30
 D7C2B8_STRBB
(D7C2B8)		 
[query] 7 - 3693 (3788)
[subject] 2 - 3621 (7498)
(9 hsp)		 0.0 2614   47% Type I modular polyketide synthase pks3-2
SBI_00651		 Streptomyces bingchenggensis (strain BCW-1)
31
 B1W4J2_STRGG
(B1W4J2)		 
[query] 40 - 3697 (3788)
[subject] 1580 - 5254 (5343)
(4 hsp)		 0.0 2592   46% Putative type-I PKS pks2-2
SGR_6180		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
32
 D1GLV8_9ACTO
(D1GLV8)		 Jump to Strply_00300 
[query] 2 - 2946 (3788)
[subject] 13 - 3014 (3479)
(4 hsp)		 0.0 2576   52% Polyketide synthase type I slgA2 Streptomyces lydicus
33
 A9YLB2_9ACTO
(A9YLB2)		 
[query] 40 - 2979 (3788)
[subject] 1071 - 3916 (4436)
(8 hsp)		 0.0 2561   53% AngAI angAI Streptomyces eurythermus
34
 A0ACI2_STRAM
(A0ACI2)		 
[query] 7 - 3785 (3788)
[subject] 3 - 3562 (3565)
 0.0 2558   47% Putative modular polyketide synthase SAMR0476 Streptomyces ambofaciens ATCC 23877
35
 C9YYI3_STRSW
(C9YYI3)		 
[query] 40 - 2979 (3788)
[subject] 1624 - 4543 (5001)
(7 hsp)		 0.0 2543   51% Putative type I polyketide synthase SCAB_83921 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
36
 F1DI32_9ACTO
(F1DI32)		 
[query] 9 - 3012 (3788)
[subject] 15 - 2986 (3378)
(4 hsp)		 0.0 2522   49% TrdAII Streptomyces sp. SCSIO1666
37
 Q3S869_9ACTO
(Q3S869)		 Jump to Conca_00080 
[query] 40 - 2979 (3788)
[subject] 1625 - 4546 (5006)
(7 hsp)		 0.0 2520   51% Modular polyketide synthase Streptomyces neyagawaensis
38
 D3Y1I4_9ACTO
(D3Y1I4)		 
[query] 9 - 3012 (3788)
[subject] 2 - 2973 (3365)
(4 hsp)		 0.0 2516   49% TamAII Streptomyces sp. 307-9
39
 A4F5C6_SORCE
(A4F5C6)		 
[query] 8 - 3696 (3788)
[subject] 2 - 3685 (5331)
(5 hsp)		 0.0 2487   44% Polyketide synthase spiG Sorangium cellulosum
Polyangium cellulosum
40
 Q6W5P7_9ACTO
(Q6W5P7)		 Jump to FR008_00190 
[query] 39 - 3786 (3788)
[subject] 4117 - 7766 (7771)
(7 hsp)		 0.0 2486   45% FscE fscE Streptomyces sp. FR-008
41
 Q9KIV3_STRAT
(Q9KIV3)		 
[query] 8 - 2764 (3788)
[subject] 2 - 2789 (3816)
(2 hsp)		 0.0 2478   53% 8,8a-deoxyoleandolide synthase 2 oleAII Streptomyces antibioticus
42
 Q5Y9G5_9ACTO
(Q5Y9G5)		 
[query] 9 - 3786 (3788)
[subject] 2 - 3567 (3574)
 0.0 2468   45% Polyketide synthase modules 3 and 4 eryAII Aeromicrobium erythreum
43
 E0KBI6_STRVO
(E0KBI6)		 
[query] 37 - 2980 (3788)
[subject] 1598 - 4547 (4996)
(6 hsp)		 0.0 2449   49% Acyl transferase StrviDRAFT_0201 Streptomyces violaceusniger Tu 4113
44
 Q7WTD6_9ACTO
(Q7WTD6)		 Jump to Nanch_00270 
[query] 7 - 2980 (3788)
[subject] 15 - 2992 (3455)
(4 hsp)		 0.0 2441   50% NanA8 nanA8 Streptomyces nanchangensis
45
 F1ADM1_9ACTO
(F1ADM1)		 
[query] 9 - 2979 (3788)
[subject] 28 - 3039 (3511)
(5 hsp)		 0.0 2436   50% BafAIV Streptomyces lohii
46
 D7BSM1_STRBB
(D7BSM1)		 
[query] 7 - 2980 (3788)
[subject] 2 - 2976 (3439)
(4 hsp)		 0.0 2429   50% Type I polyketide synthase nanA8
SBI_08400		 Streptomyces bingchenggensis (strain BCW-1)
47
 E2Q518_STRCL
(E2Q518)		 
[query] 9 - 2987 (3788)
[subject] 16 - 3117 (3596)
(4 hsp)		 0.0 2405   49% Modular polyketide synthase SCLAV_0012 Streptomyces clavuligerus ATCC 27064
48
 D1GLV9_9ACTO
(D1GLV9)		 Jump to Strply_00310 
[query] 40 - 2998 (3788)
[subject] 2622 - 5640 (6171)
(11 hsp)		 0.0 2392   49% Polyketide synthase type I slgA1 Streptomyces lydicus
49
 E4NJF4_KITSK
(E4NJF4)		 
[query] 13 - 2979 (3788)
[subject] 1 - 2964 (3436)
(4 hsp)		 0.0 2375   50% Modular polyketide synthase BFAS4 bfmA4
KSE_73470		 Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
50
 E0KN03_STRVO
(E0KN03)		 
[query] 40 - 2764 (3788)
[subject] 1018 - 3634 (3735)
(6 hsp)		 0.0 2372   53% 6-deoxyerythronolide-B synthase., Mycocerosate synthase StrviDRAFT_3962 Streptomyces violaceusniger Tu 4113 2.3.1.111

2.3.1.94
51
 D9WQ82_9ACTO
(D9WQ82)		 
[query] 8 - 2415 (3788)
[subject] 3 - 2458 (3199)
(4 hsp)		 0.0 2368   56% Erythronolide synthase, modules 1 and 2 SSOG_05756 Streptomyces himastatinicus ATCC 53653
52
 A0FCL1_STRVO
(A0FCL1)		 Jump to Merid_00020 
[query] 40 - 2764 (3788)
[subject] 1067 - 3682 (5721)
(12 hsp)		 0.0 2358   52% MerA merA Streptomyces violaceoniger
53
 Q1WEK9_9ACTO
(Q1WEK9)		 
[query] 40 - 2764 (3788)
[subject] 1061 - 3677 (5712)
(12 hsp)		 0.0 2353   52% Polyketide synthase merA Streptomyces sp. NRRL 30748
54
 E0KBI1_STRVO
(E0KBI1)		 
[query] 8 - 2985 (3788)
[subject] 2 - 2991 (3456)
(4 hsp)		 0.0 2342   47% Acyl transferase StrviDRAFT_0196 Streptomyces violaceusniger Tu 4113
55
 D5ZU03_9ACTO
(D5ZU03)		 
[query] 40 - 2764 (3788)
[subject] 1474 - 4080 (4652)
(9 hsp)		 0.0 2342   53% Type I modular polyketide synthase SSFG_00092 Streptomyces ghanaensis ATCC 14672
56
 O33954_STRFR
(O33954)		 
[query] 39 - 3012 (3788)
[subject] 1059 - 4031 (4472)
(9 hsp)		 0.0 2324   51% Tylactone synthase starter module and modules 1 & 2 tylG Streptomyces fradiae
Streptomyces roseoflavus
57
 B4VB12_9ACTO
(B4VB12)		 
[query] 9 - 2426 (3788)
[subject] 3 - 2482 (3203)
(4 hsp)		 0.0 2319   54% Polyketide synthase type I SSAG_04922 Streptomyces sp. Mg1
58
 D3Y1I3_9ACTO
(D3Y1I3)		 
[query] 36 - 2980 (3788)
[subject] 2529 - 5366 (5828)
(10 hsp)		 0.0 2309   48% TamAI Streptomyces sp. 307-9
59
 F1DI31_9ACTO
(F1DI31)		 
[query] 36 - 2980 (3788)
[subject] 2529 - 5367 (5829)
(10 hsp)		 0.0 2302   48% TrdAI Streptomyces sp. SCSIO1666
60
 Q52V51_9ACTO
(Q52V51)		 
[query] 9 - 2415 (3788)
[subject] 3 - 2502 (3227)
(5 hsp)		 0.0 2301   55% Polyketide synthase type I Streptomyces aizunensis
61
 D9W5P0_9ACTO
(D9W5P0)		 
[query] 8 - 2788 (3788)
[subject] 4 - 2798 (3748)
(2 hsp)		 0.0 2298   51% Modular polyketide synthase SSNG_07470 Streptomyces sp. C
62
 Q93HJ1_STRAW
(Q93HJ1)		 Jump to Oligo_00120 
[query] 9 - 2980 (3788)
[subject] 2 - 2924 (3613)
(4 hsp)		 0.0 2295   48% Modular polyketide synthase olmA7
SAV2895
SAV_2895		 Streptomyces avermitilis
63
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 34 - 3009 (3788)
[subject] 3656 - 6632 (7026)
(11 hsp)		 0.0 2290   47% Polyketide synthase pldAII Streptomyces platensis
64
 C9YYI1_STRSW
(C9YYI1)		 
[query] 9 - 2417 (3788)
[subject] 3 - 2462 (4970)
(8 hsp)		 0.0 2284   55% Putative type I polyketide synthase SCAB_83901 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
65
 Q3S864_9ACTO
(Q3S864)		 Jump to Conca_00060 
[query] 9 - 2417 (3788)
[subject] 3 - 2458 (4970)
(8 hsp)		 0.0 2274   55% Nodular polyketide synthase Streptomyces neyagawaensis
66
 Q9KIV4_STRAT
(Q9KIV4)		 
[query] 40 - 2418 (3788)
[subject] 1062 - 3423 (4150)
(8 hsp)		 0.0 2267   57% 8,8a-deoxyoleandolide synthase 1 oleAI Streptomyces antibioticus
67
 E0KBI4_STRVO
(E0KBI4)		 
[query] 40 - 2764 (3788)
[subject] 4507 - 7279 (8275)
(8 hsp)		 0.0 2250   48% Beta-ketoacyl synthase StrviDRAFT_0199 Streptomyces violaceusniger Tu 4113
68
 A1YAM9_AMYOR
(A1YAM9)		 
[query] 9 - 2998 (3788)
[subject] 3 - 2850 (3264)
(4 hsp)		 0.0 2245   48% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
69
 B1W487_STRGG
(B1W487)		 
[query] 8 - 2417 (3788)
[subject] 3 - 2447 (3188)
(5 hsp)		 0.0 2244   54% Putative type-I PKS pks1-3
SGR_6075		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
70
 Q0ILD0_9ACTO
(Q0ILD0)		 
[query] 9 - 3009 (3788)
[subject] 2 - 2938 (3593)
(4 hsp)		 0.0 2240   46% NlmA7 nlmA7 Streptomyces nanchangensis
71
 D3U9Y9_9ACTO
(D3U9Y9)		 
[query] 8 - 2791 (3788)
[subject] 24 - 2833 (3405)
(5 hsp)		 0.0 2239   50% Type I polyketide synthase sfaI Streptomyces flaveolus
72
 B1W4J5_STRGG
(B1W4J5)		 
[query] 8 - 3009 (3788)
[subject] 2 - 2934 (3579)
(5 hsp)		 0.0 2234   49% Putative type-I PKS pks2-5
SGR_6183		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
73
 B6ZIR2_STRPT
(B6ZIR2)		 Jump to Pladi_00010 
[query] 40 - 2984 (3788)
[subject] 1016 - 3971 (6532)
(9 hsp)		 0.0 2232   47% Polyketide synthase pldAI Streptomyces platensis
74
 B1W485_STRGG
(B1W485)		 
[query] 36 - 2979 (3788)
[subject] 1772 - 4669 (5136)
(8 hsp)		 0.0 2230   49% Putative type-I PKS pks1-1
SGR_6073		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
75
 Q68BG4_STRHA
(Q68BG4)		 Jump to Halsto_00020 
[query] 9 - 2979 (3788)
[subject] 3 - 2959 (7111)
(9 hsp)		 0.0 2222   47% Type I polyketide synthase hlsB Streptomyces halstedii
76
 E0KFI7_STRVO
(E0KFI7)		 
[query] 34 - 2980 (3788)
[subject] 5109 - 8039 (8538)
(12 hsp)		 0.0 2209   47% Beta-ketoacyl synthase StrviDRAFT_1370 Streptomyces violaceusniger Tu 4113
77
 Q0PD02_STRHA
(Q0PD02)		 Jump to Halsto_00030 
[query] 8 - 3009 (3788)
[subject] 2 - 3010 (5220)
(7 hsp)		 0.0 2207   47% Type I polyketide synthase hlsC Streptomyces halstedii
78
 F1ADL9_9ACTO
(F1ADL9)		 
[query] 8 - 2442 (3788)
[subject] 2 - 2540 (5145)
(9 hsp)		 0.0 2202   52% BafAII Streptomyces lohii
79
 Q68BG3_STRHA
(Q68BG3)		 
[query] 8 - 3009 (3788)
[subject] 2 - 3010 (3367)
(4 hsp)		 0.0 2202   47% Type I polyketide synthase hlsC Streptomyces halstedii
80
 E0D202_9ACTO
(E0D202)		 Jump to FD891_00010 
[query] 40 - 2420 (3788)
[subject] 1038 - 3419 (7480)
(13 hsp)		 0.0 2201   54% Polyketide synthase gfsA Streptomyces graminofaciens
81
 E4NJF2_KITSK
(E4NJF2)		 
[query] 8 - 2415 (3788)
[subject] 2 - 2474 (5004)
(9 hsp)		 0.0 2193   54% Modular polyketide synthase BFAS2 bfmA2
KSE_73450		 Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
82
 Q846W6_STRCM
(Q846W6)		 Jump to Monen_00250 
[query] 8 - 2747 (3788)
[subject] 2 - 2768 (3753)
 0.0 2191   48% Monensin polyketide synthase modules 11 and 12 monAVIII Streptomyces cinnamonensis
83
 Q9L4W4_9ACTO
(Q9L4W4)		 Jump to Nysta_00140 
[query] 9 - 2415 (3788)
[subject] 11 - 2464 (3192)
(4 hsp)		 0.0 2191   53% NysB nysB Streptomyces noursei
84
 Q93HJ2_STRAW
(Q93HJ2)		 Jump to Oligo_00110 
[query] 40 - 2417 (3788)
[subject] 1567 - 3965 (4685)
(7 hsp)		 0.0 2187   54% Modular polyketide synthase olmA6
SAV2896
SAV_2896		 Streptomyces avermitilis
85
 E0KBI0_STRVO
(E0KBI0)		 
[query] 1064 - 3788 (3788)
[subject] 1298 - 3955 (3955)
(5 hsp)		 0.0 2186   50% Acyl transferase StrviDRAFT_0195 Streptomyces violaceusniger Tu 4113
86
 A8L4B1_FRASN
(A8L4B1)		 
[query] 8 - 2792 (3788)
[subject] 2 - 2910 (3493)
(4 hsp)		 0.0 2169   49% Beta-ketoacyl synthase Franean1_3889 Frankia sp. (strain EAN1pec)
87
 Q0ILD1_9ACTO
(Q0ILD1)		 
[query] 12 - 2418 (3788)
[subject] 3 - 2422 (4635)
(6 hsp)		 0.0 2165   53% NlmA6 nlmA6 Streptomyces nanchangensis
88
 Q93NW7_9ACTO
(Q93NW7)		 Jump to Amph_00160 
[query] 8 - 2415 (3788)
[subject] 7 - 2462 (3190)
(6 hsp)		 0.0 2157   52% AmphB amphB Streptomyces nodosus
89
 D5ZU01_9ACTO
(D5ZU01)		 
[query] 8 - 2415 (3788)
[subject] 30 - 2435 (4790)
(8 hsp)		 0.0 2156   53% Nodular polyketide synthase SSFG_00090 Streptomyces ghanaensis ATCC 14672
90
 D6C473_9ACTO
(D6C473)		 Jump to Meili_00240 
[query] 42 - 2986 (3788)
[subject] 2583 - 5491 (5987)
(10 hsp)		 0.0 2149   45% Modular polyketide synthase meiA2 Streptomyces nanchangensis
91
 E9LIP5_9ACTO
(E9LIP5)		 
[query] 3 - 2715 (3788)
[subject] 8 - 2629 (3205)
(4 hsp)		 0.0 2148   49% Putative modular polyketide synthase tiaA2 Dactylosporangium aurantiacum subsp. hamdenensis
92
 B4VBW0_9ACTO
(B4VBW0)		 
[query] 28 - 3012 (3788)
[subject] 5023 - 7949 (10873)
(15 hsp)		 0.0 2147   46% Polyketide synthase type I SSAG_05337 Streptomyces sp. Mg1
93
 Q9ZGI5_9ACTO
(Q9ZGI5)		 Jump to Pikro_00030 
[query] 40 - 2994 (3788)
[subject] 1109 - 4095 (4613)
(8 hsp)		 0.0 2142   47% Type I polyketide synthase PikAI pikAI Streptomyces venezuelae
94
 D9WQ70_9ACTO
(D9WQ70)		 
[query] 40 - 2980 (3788)
[subject] 823 - 3714 (5483)
(9 hsp)		 0.0 2142   47% Modular polyketide synthase SSOG_05744 Streptomyces himastatinicus ATCC 53653
95
 E0KFI9_STRVO
(E0KFI9)		 
[query] 42 - 2987 (3788)
[subject] 1703 - 4634 (8238)
(13 hsp)		 0.0 2137   46% Beta-ketoacyl synthase StrviDRAFT_1372 Streptomyces violaceusniger Tu 4113
96
 E0KBI2_STRVO
(E0KBI2)		 
[query] 40 - 2420 (3788)
[subject] 1760 - 4200 (4930)
(9 hsp)		 0.0 2133   52% Mycocerosate synthase., 6-deoxyerythronolide-B synthase StrviDRAFT_0197 Streptomyces violaceusniger Tu 4113 2.3.1.111

2.3.1.94
97
 D2CKM3_PSEAH
(D2CKM3)		 
[query] 9 - 2437 (3788)
[subject] 7 - 2474 (3175)
(4 hsp)		 0.0 2123   53% CppB cppB Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
98
 D9WQ74_9ACTO
(D9WQ74)		 
[query] 9 - 3012 (3788)
[subject] 3 - 2979 (3286)
(4 hsp)		 0.0 2122   45% Modular polyketide synthase SSOG_05748 Streptomyces himastatinicus ATCC 53653
99
 D9T6W4_MICAI
(D9T6W4)		 
[query] 7 - 2979 (3788)
[subject] 2 - 2962 (9936)
(14 hsp)		 0.0 2101   46% Beta-ketoacyl synthase Micau_2464 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
100
 E8S0C5_MICSL
(E8S0C5)		 
[query] 7 - 2979 (3788)
[subject] 2 - 2962 (9937)
(15 hsp)		 0.0 2100   46% Beta-ketoacyl synthase ML5_5898 Micromonospora sp. (strain L5)
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 Q5SFB2_STRBI
(Q5SFB2)		 
[query] 1 - 3788 (3788)
[subject] 1 - 3788 (3788)
 0.0 7400   100%
Product
Polyketide synthase subunit
Gene
chmGIII
Organism
Streptomyces bikiniensis
1uniprot[Pubmed] 15561847
Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.(Antimicrob. Agents Chemother.) [2004]
3
 Q8KPW3_9ACTO
(Q8KPW3)		 
[query] 21 - 3788 (3788)
[subject] 1 - 3734 (3734)
 0.0 5997   87%
Product
Putative type I polyketide synthase
Gene
gerSIII
Organism
Streptomyces sp. KCTC 0041BP
1uniprot[Pubmed] 17053005
Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007]
2uniprot
Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006]
6
 Q5SFB4_STRBI
(Q5SFB4)		 Jump to Chalc_00210 
[query] 40 - 3012 (3788)
[subject] 1063 - 3986 (4441)
(9 hsp)		 0.0 3524   67%
Product
Polyketide synthase subunit
Gene
chmGI
Organism
Streptomyces bikiniensis
1uniprot[Pubmed] 15561847
Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.(Antimicrob. Agents Chemother.) [2004]
7
 Q83WE8_MICGR
(Q83WE8)		 
[query] 7 - 3788 (3788)
[subject] 3 - 3649 (3649)
 0.0 3297   55%
Product
Protomycinolide IV synthase 3
Gene
mycAIII
Organism
Micromonospora griseorubida
1uniprot[Pubmed] 12583909 [Medline] 22472038
Organization of the biosynthetic gene cluster for the polyketide macrolide mycinamicin in Micromonospora griseorubida.(FEMS Microbiol. Lett.) [2003]
8
 Q8KPW5_9ACTO
(Q8KPW5)		 
[query] 5 - 3012 (3788)
[subject] 978 - 3929 (4387)
(8 hsp)		 0.0 3293   64%
Product
Putative type I polyketide synthase
Gene
gerSI
Organism
Streptomyces sp. KCTC 0041BP
1uniprot[Pubmed] 17053005
Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007]
2uniprot
Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006]
9
 Q9ZGI4_9ACTO
(Q9ZGI4)		 Jump to Pikro_00040 
[query] 9 - 3788 (3788)
[subject] 5 - 3737 (3739)
 0.0 3210   53%
Product
Type I polyketide synthase PikAII
Gene
pikAII
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 9770448 [Medline] 98445333
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998]
12
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 40 - 3692 (3788)
[subject] 1729 - 5297 (7102)
(12 hsp)		 0.0 3054   51%
Product
Polyketide synthase
Gene
merB
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
13
 A0FCL2_STRVO
(A0FCL2)		 Jump to Merid_00030 
[query] 40 - 3692 (3788)
[subject] 1734 - 5373 (7178)
(13 hsp)		 0.0 3044   51%
Product
MerB
Gene
merB
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
14
 A4F7P0_SACEN
(A4F7P0)		 
[query] 8 - 3786 (3788)
[subject] 2 - 3562 (3567)
 0.0 2823   48%
Product
EryAII Erythromycin polyketide synthase modules 3 and 4
Gene
eryAII
SACE_0723
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
2uniprot[Pubmed] 17719492
Structural and mechanistic analysis of protein interactions in module 3 of the 6-deoxyerythronolide B synthase.(Chem. Biol.) [2007]
[pubmed all]
15
 Q5UNP5_SACER
(Q5UNP5)		 
[query] 8 - 3786 (3788)
[subject] 2 - 3562 (3567)
 0.0 2823   48%
Product
EryAII
Gene
eryAII
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 15496466
Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
16
 ERYA2_SACER
(Q03132)		 
[query] 8 - 3786 (3788)
[subject] 2 - 3562 (3567)
 0.0 2810   48%
Product
Erythronolide synthase, modules 3 and 4
6-deoxyerythronolide B synthase II
DEBS 2
ORF 2
Gene
eryA
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 2024119 [Medline] 91220065
Modular organization of genes required for complex polyketide biosynthesis.(Science) [1991]
2uniprot[Pubmed] 1740151 [Medline] 92155230
6-deoxyerythronolide-B synthase 2 from Saccharopolyspora erythraea. Cloning of the structural gene, sequence analysis and inferred domain structure of the multifunctional enzyme.(Eur. J. Biochem.) [1992]
3uniprot[Pubmed] 1618327
Identification of DEBS 1, DEBS 2 and DEBS 3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase from Saccharopolyspora erythraea.(FEBS Lett.) [1992]
4uniprot[Pubmed] 12954331
The structure of docking domains in modular polyketide synthases.(Chem. Biol.) [2003]
[pubmed all]
17
 Q9F829_9ACTO
(Q9F829)		 Jump to Megalo_00130 
[query] 8 - 3786 (3788)
[subject] 2 - 3557 (3562)
 0.0 2782   48%
Product
Megalomicin 6-deoxyerythronolide B synthase 2
Gene
megAII
Organism
Micromonospora megalomicea subsp. nigra
1uniprot[Pubmed] 10972798 [Medline] 20430101
Biosynthesis of the anti-parasitic agent megalomicin: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea.(Mol. Microbiol.) [2000]
19
 A0FCL3_STRVO
(A0FCL3)		 Jump to Merid_00040 
[query] 30 - 3692 (3788)
[subject] 5933 - 9538 (11604)
(15 hsp)		 0.0 2746   48%
Product
MerC
Gene
merC
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
20
 C5HV14_STRAT
(C5HV14)		 Jump to Indano_00160 
[query] 45 - 3695 (3788)
[subject] 1094 - 4701 (4779)
(6 hsp)		 0.0 2745   48%
Product
Polyketide synthase
Gene
idmL
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
21
 Q83X70_STRRO
(Q83X70)		 
[query] 8 - 3787 (3788)
[subject] 2 - 3651 (3656)
 0.0 2738   47%
Product
Lankamycin synthase LkmAII
Gene
lkmAII
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
24
 A0ACH1_STRAM
(A0ACH1)		 
[query] 8 - 3692 (3788)
[subject] 3 - 3570 (8154)
(9 hsp)		 0.0 2734   48%
Product
Putative polyketide synthase B
Gene
SAMR0465
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
26
 D6C4C5_9ACTO
(D6C4C5)		 Jump to Meili_00790 
[query] 40 - 3788 (3788)
[subject] 578 - 4330 (4330)
(5 hsp)		 0.0 2721   46%
Product
Modular polyketide synthase
Gene
meiA1
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
27
 Q93HJ5_STRAW
(Q93HJ5)		 Jump to Oligo_00080 
[query] 40 - 3787 (3788)
[subject] 2467 - 6144 (6146)
(7 hsp)		 0.0 2720   48%
Product
Modular polyketide synthase
Gene
olmA1
SAV2899
SAV_2899
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
28
 D7C488_STRBB
(D7C488)		 
[query] 40 - 3788 (3788)
[subject] 587 - 4343 (4343)
(5 hsp)		 0.0 2718   46%
Product
Type I polyketide synthase
Gene
milA1
SBI_00789
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
29
 Q53840_SORCE
(Q53840)		 Jump to Soraph_00080 
[query] 8 - 3700 (3788)
[subject] 2 - 3660 (8817)
(10 hsp)		 0.0 2627   45%
Product
Soraphen polyketide synthase B
Gene
sorB
Organism
Sorangium cellulosum
Polyangium cellulosum
1uniprot[Pubmed] 7601830 [Medline] 95325306
A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes.(J. Bacteriol.) [1995]
2uniprot[Pubmed] 12039053 [Medline] 22035375
Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.(Gene) [2002]
[pubmed all]
30
 D7C2B8_STRBB
(D7C2B8)		 
[query] 7 - 3693 (3788)
[subject] 2 - 3621 (7498)
(9 hsp)		 0.0 2614   47%
Product
Type I modular polyketide synthase
Gene
pks3-2
SBI_00651
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
31
 B1W4J2_STRGG
(B1W4J2)		 
[query] 40 - 3697 (3788)
[subject] 1580 - 5254 (5343)
(4 hsp)		 0.0 2592   46%
Product
Putative type-I PKS
Gene
pks2-2
SGR_6180
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
32
 D1GLV8_9ACTO
(D1GLV8)		 Jump to Strply_00300 
[query] 2 - 2946 (3788)
[subject] 13 - 3014 (3479)
(4 hsp)		 0.0 2576   52%
Product
Polyketide synthase type I
Gene
slgA2
Organism
Streptomyces lydicus
1uniprot
Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009]
34
 A0ACI2_STRAM
(A0ACI2)		 
[query] 7 - 3785 (3788)
[subject] 3 - 3562 (3565)
 0.0 2558   47%
Product
Putative modular polyketide synthase
Gene
SAMR0476
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
35
 C9YYI3_STRSW
(C9YYI3)		 
[query] 40 - 2979 (3788)
[subject] 1624 - 4543 (5001)
(7 hsp)		 0.0 2543   51%
Product
Putative type I polyketide synthase
Gene
SCAB_83921
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
36
 F1DI32_9ACTO
(F1DI32)		 
[query] 9 - 3012 (3788)
[subject] 15 - 2986 (3378)
(4 hsp)		 0.0 2522   49%
Product
TrdAII
Gene
 
Organism
Streptomyces sp. SCSIO1666
1uniprot[Pubmed] 21329667
Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011]
37
 Q3S869_9ACTO
(Q3S869)		 Jump to Conca_00080 
[query] 40 - 2979 (3788)
[subject] 1625 - 4546 (5006)
(7 hsp)		 0.0 2520   51%
Product
Modular polyketide synthase
Gene
 
Organism
Streptomyces neyagawaensis
1uniprot[Pubmed] 16207901
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005]
38
 D3Y1I4_9ACTO
(D3Y1I4)		 
[query] 9 - 3012 (3788)
[subject] 2 - 2973 (3365)
(4 hsp)		 0.0 2516   49%
Product
TamAII
Gene
 
Organism
Streptomyces sp. 307-9
1uniprot[Pubmed] 20127927
Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010]
39
 A4F5C6_SORCE
(A4F5C6)		 
[query] 8 - 3696 (3788)
[subject] 2 - 3685 (5331)
(5 hsp)		 0.0 2487   44%
Product
Polyketide synthase
Gene
spiG
Organism
Sorangium cellulosum
Polyangium cellulosum
1uniprot[Pubmed] 17317575
Spiroketal polyketide formation in Sorangium: Identification of the biosynthetic gene cluster for the highly cytotoxic spirangienes.(Chem. Biol.) [2007]
40
 Q6W5P7_9ACTO
(Q6W5P7)		 Jump to FR008_00190 
[query] 39 - 3786 (3788)
[subject] 4117 - 7766 (7771)
(7 hsp)		 0.0 2486   45%
Product
FscE
Gene
fscE
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
41
 Q9KIV3_STRAT
(Q9KIV3)		 
[query] 8 - 2764 (3788)
[subject] 2 - 2789 (3816)
(2 hsp)		 0.0 2478   53%
Product
8,8a-deoxyoleandolide synthase 2
Gene
oleAII
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 10908114 [Medline] 20363406
Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin.(J. Antibiot.) [2000]
42
 Q5Y9G5_9ACTO
(Q5Y9G5)		 
[query] 9 - 3786 (3788)
[subject] 2 - 3567 (3574)
 0.0 2468   45%
Product
Polyketide synthase modules 3 and 4
Gene
eryAII
Organism
Aeromicrobium erythreum
1uniprot[Pubmed] 15257441
The erythromycin biosynthetic gene cluster of Aeromicrobium erythreum.(J. Ind. Microbiol. Biotechnol.) [2004]
44
 Q7WTD6_9ACTO
(Q7WTD6)		 Jump to Nanch_00270 
[query] 7 - 2980 (3788)
[subject] 15 - 2992 (3455)
(4 hsp)		 0.0 2441   50%
Product
NanA8
Gene
nanA8
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12770825 [Medline] 22654646
A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin.(Chem. Biol.) [2003]
46
 D7BSM1_STRBB
(D7BSM1)		 
[query] 7 - 2980 (3788)
[subject] 2 - 2976 (3439)
(4 hsp)		 0.0 2429   50%
Product
Type I polyketide synthase
Gene
nanA8
SBI_08400
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
47
 E2Q518_STRCL
(E2Q518)		 
[query] 9 - 2987 (3788)
[subject] 16 - 3117 (3596)
(4 hsp)		 0.0 2405   49%
Product
Modular polyketide synthase
Gene
SCLAV_0012
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
48
 D1GLV9_9ACTO
(D1GLV9)		 Jump to Strply_00310 
[query] 40 - 2998 (3788)
[subject] 2622 - 5640 (6171)
(11 hsp)		 0.0 2392   49%
Product
Polyketide synthase type I
Gene
slgA1
Organism
Streptomyces lydicus
1uniprot
Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009]
49
 E4NJF4_KITSK
(E4NJF4)		 
[query] 13 - 2979 (3788)
[subject] 1 - 2964 (3436)
(4 hsp)		 0.0 2375   50%
Product
Modular polyketide synthase BFAS4
Gene
bfmA4
KSE_73470
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
52
 A0FCL1_STRVO
(A0FCL1)		 Jump to Merid_00020 
[query] 40 - 2764 (3788)
[subject] 1067 - 3682 (5721)
(12 hsp)		 0.0 2358   52%
Product
MerA
Gene
merA
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
53
 Q1WEK9_9ACTO
(Q1WEK9)		 
[query] 40 - 2764 (3788)
[subject] 1061 - 3677 (5712)
(12 hsp)		 0.0 2353   52%
Product
Polyketide synthase
Gene
merA
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
56
 O33954_STRFR
(O33954)		 
[query] 39 - 3012 (3788)
[subject] 1059 - 4031 (4472)
(9 hsp)		 0.0 2324   51%
Product
Tylactone synthase starter module and modules 1 & 2
Gene
tylG
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 17719489
A tylosin ketoreductase reveals how chirality is determined in polyketides.(Chem. Biol.) [2007]
58
 D3Y1I3_9ACTO
(D3Y1I3)		 
[query] 36 - 2980 (3788)
[subject] 2529 - 5366 (5828)
(10 hsp)		 0.0 2309   48%
Product
TamAI
Gene
 
Organism
Streptomyces sp. 307-9
1uniprot[Pubmed] 20127927
Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010]
59
 F1DI31_9ACTO
(F1DI31)		 
[query] 36 - 2980 (3788)
[subject] 2529 - 5367 (5829)
(10 hsp)		 0.0 2302   48%
Product
TrdAI
Gene
 
Organism
Streptomyces sp. SCSIO1666
1uniprot[Pubmed] 21329667
Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011]
60
 Q52V51_9ACTO
(Q52V51)		 
[query] 9 - 2415 (3788)
[subject] 3 - 2502 (3227)
(5 hsp)		 0.0 2301   55%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
62
 Q93HJ1_STRAW
(Q93HJ1)		 Jump to Oligo_00120 
[query] 9 - 2980 (3788)
[subject] 2 - 2924 (3613)
(4 hsp)		 0.0 2295   48%
Product
Modular polyketide synthase
Gene
olmA7
SAV2895
SAV_2895
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
63
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 34 - 3009 (3788)
[subject] 3656 - 6632 (7026)
(11 hsp)		 0.0 2290   47%
Product
Polyketide synthase
Gene
pldAII
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
64
 C9YYI1_STRSW
(C9YYI1)		 
[query] 9 - 2417 (3788)
[subject] 3 - 2462 (4970)
(8 hsp)		 0.0 2284   55%
Product
Putative type I polyketide synthase
Gene
SCAB_83901
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
65
 Q3S864_9ACTO
(Q3S864)		 Jump to Conca_00060 
[query] 9 - 2417 (3788)
[subject] 3 - 2458 (4970)
(8 hsp)		 0.0 2274   55%
Product
Nodular polyketide synthase
Gene
 
Organism
Streptomyces neyagawaensis
1uniprot[Pubmed] 16207901
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005]
66
 Q9KIV4_STRAT
(Q9KIV4)		 
[query] 40 - 2418 (3788)
[subject] 1062 - 3423 (4150)
(8 hsp)		 0.0 2267   57%
Product
8,8a-deoxyoleandolide synthase 1
Gene
oleAI
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 10908114 [Medline] 20363406
Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin.(J. Antibiot.) [2000]
68
 A1YAM9_AMYOR
(A1YAM9)		 
[query] 9 - 2998 (3788)
[subject] 3 - 2850 (3264)
(4 hsp)		 0.0 2245   48%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
69
 B1W487_STRGG
(B1W487)		 
[query] 8 - 2417 (3788)
[subject] 3 - 2447 (3188)
(5 hsp)		 0.0 2244   54%
Product
Putative type-I PKS
Gene
pks1-3
SGR_6075
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
71
 D3U9Y9_9ACTO
(D3U9Y9)		 
[query] 8 - 2791 (3788)
[subject] 24 - 2833 (3405)
(5 hsp)		 0.0 2239   50%
Product
Type I polyketide synthase
Gene
sfaI
Organism
Streptomyces flaveolus
1uniprot
Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010]
72
 B1W4J5_STRGG
(B1W4J5)		 
[query] 8 - 3009 (3788)
[subject] 2 - 2934 (3579)
(5 hsp)		 0.0 2234   49%
Product
Putative type-I PKS
Gene
pks2-5
SGR_6183
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
73
 B6ZIR2_STRPT
(B6ZIR2)		 Jump to Pladi_00010 
[query] 40 - 2984 (3788)
[subject] 1016 - 3971 (6532)
(9 hsp)		 0.0 2232   47%
Product
Polyketide synthase
Gene
pldAI
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
74
 B1W485_STRGG
(B1W485)		 
[query] 36 - 2979 (3788)
[subject] 1772 - 4669 (5136)
(8 hsp)		 0.0 2230   49%
Product
Putative type-I PKS
Gene
pks1-1
SGR_6073
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
75
 Q68BG4_STRHA
(Q68BG4)		 Jump to Halsto_00020 
[query] 9 - 2979 (3788)
[subject] 3 - 2959 (7111)
(9 hsp)		 0.0 2222   47%
Product
Type I polyketide synthase
Gene
hlsB
Organism
Streptomyces halstedii
1uniprot
Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004]
79
 Q68BG3_STRHA
(Q68BG3)		 
[query] 8 - 3009 (3788)
[subject] 2 - 3010 (3367)
(4 hsp)		 0.0 2202   47%
Product
Type I polyketide synthase
Gene
hlsC
Organism
Streptomyces halstedii
1uniprot
Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004]
80
 E0D202_9ACTO
(E0D202)		 Jump to FD891_00010 
[query] 40 - 2420 (3788)
[subject] 1038 - 3419 (7480)
(13 hsp)		 0.0 2201   54%
Product
Polyketide synthase
Gene
gfsA
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
81
 E4NJF2_KITSK
(E4NJF2)		 
[query] 8 - 2415 (3788)
[subject] 2 - 2474 (5004)
(9 hsp)		 0.0 2193   54%
Product
Modular polyketide synthase BFAS2
Gene
bfmA2
KSE_73450
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
82
 Q846W6_STRCM
(Q846W6)		 Jump to Monen_00250 
[query] 8 - 2747 (3788)
[subject] 2 - 2768 (3753)
 0.0 2191   48%
Product
Monensin polyketide synthase modules 11 and 12
Gene
monAVIII
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 12940979 [Medline] 22823264
Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization.(Mol. Microbiol.) [2003]
2uniprot
The gene cluster for monensin biosynthesis. [1999]
83
 Q9L4W4_9ACTO
(Q9L4W4)		 Jump to Nysta_00140 
[query] 9 - 2415 (3788)
[subject] 11 - 2464 (3192)
(4 hsp)		 0.0 2191   53%
Product
NysB
Gene
nysB
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
84
 Q93HJ2_STRAW
(Q93HJ2)		 Jump to Oligo_00110 
[query] 40 - 2417 (3788)
[subject] 1567 - 3965 (4685)
(7 hsp)		 0.0 2187   54%
Product
Modular polyketide synthase
Gene
olmA6
SAV2896
SAV_2896
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
86
 A8L4B1_FRASN
(A8L4B1)		 
[query] 8 - 2792 (3788)
[subject] 2 - 2910 (3493)
(4 hsp)		 0.0 2169   49%
Product
Beta-ketoacyl synthase
Gene
Franean1_3889
Organism
Frankia sp. (strain EAN1pec)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
88
 Q93NW7_9ACTO
(Q93NW7)		 Jump to Amph_00160 
[query] 8 - 2415 (3788)
[subject] 7 - 2462 (3190)
(6 hsp)		 0.0 2157   52%
Product
AmphB
Gene
amphB
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
3uniprot[Pubmed] 20696392
Structural and functional analysis of A-type ketoreductases from the amphotericin modular polyketide synthase.(Structure) [2010]
[pubmed all]
90
 D6C473_9ACTO
(D6C473)		 Jump to Meili_00240 
[query] 42 - 2986 (3788)
[subject] 2583 - 5491 (5987)
(10 hsp)		 0.0 2149   45%
Product
Modular polyketide synthase
Gene
meiA2
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
91
 E9LIP5_9ACTO
(E9LIP5)		 
[query] 3 - 2715 (3788)
[subject] 8 - 2629 (3205)
(4 hsp)		 0.0 2148   49%
Product
Putative modular polyketide synthase
Gene
tiaA2
Organism
Dactylosporangium aurantiacum subsp. hamdenensis
1uniprot[Pubmed] 21186805
Characterization of tiacumicin B biosynthetic gene cluster affording diversified tiacumicin analogues and revealing a tailoring dihalogenase.(J. Am. Chem. Soc.) [2011]
93
 Q9ZGI5_9ACTO
(Q9ZGI5)		 Jump to Pikro_00030 
[query] 40 - 2994 (3788)
[subject] 1109 - 4095 (4613)
(8 hsp)		 0.0 2142   47%
Product
Type I polyketide synthase PikAI
Gene
pikAI
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 9770448 [Medline] 98445333
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998]
97
 D2CKM3_PSEAH
(D2CKM3)		 
[query] 9 - 2437 (3788)
[subject] 7 - 2474 (3175)
(4 hsp)		 0.0 2123   53%
Product
CppB
Gene
cppB
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]