遺伝子 : Streptogramin A acetyltransferase (VAT)

遺伝子情報

ID	NRULE_0113
遺伝子ID	VAT
作成日	2013/01/17
タンパク質名	Protein name Full Streptogramin A acetyltransferase EC EC 2.3.1.- Synonym Full Virginiamycin acetyltransferase
遺伝子名	vatD
遺伝子条件	BLASTP; P26839; hit=1; score=500; pid=50
参照	Gene Ontology GO GO:0016746, F:transferase activity, transferring acyl groups, IEA:UniProtKB-KW GO:0046677, P:response to antibiotic, IEA:UniProtKB-KW Family and domain databases InterPro IPR001451, Hexapep_transf IPR018357, Hexapep_transf_CS IPR011004, Trimer_LpxA-like Pfam PF00132, Hexapep, 1 PROSITE PS00101, HEXAPEP_TRANSFERASES, 1
配列の特徴	P50870 Enterococcus faecium (Streptococcus faecium). ACT_SITE 82
注釈	Function Inactivates the A compounds of virginiamycin-like antibiotics, thus providing resistance to these antibiotics Sequence similarities Belongs to the transferase hexapeptide repeat family
参考文献	P26839 Staphylococcus aureus. 8344533 Sequence of a staphylococcal gene, vat, encoding an acetyltransferase inactivating the A-type compounds of virginiamycin-like antibiotics. (Gene. 1993) P50870 Enterococcus faecium (Streptococcus faecium). 8257133 Identification of the satA gene encoding a streptogramin A acetyltransferase in Enterococcus faecium BM4145. (Antimicrob Agents Chemother. 1993)

関与する機能

機能名
Streptogramin resistance

該当CDS

学名	NBRC番号	CDS	タンパク質名
Acaryochloris marina	102967	AM1_5174	acetyltransferase
Bacillus cereus	15305	BC_2611	Virginiamycin A acetyltransferase
Bacillus pseudomycoides	101232	bpmyx0001_22440	Virginiamycin A acetyltransferase
Dehalococcoides mccartyi		DehaBAV1_0994	Acetyltransferase (isoleucine patch superfamily)-like protein
Fischerella sp.		PCC9339_RS0123235	Vat family streptogramin A O-acetyltransferase
Myroides odoratus	14945	Myrod_3713	transferase hexapeptide repeat containing protein
Oscillibacter valericigenes	101213	OBV_21670	acetyltransferase
Synechocystis sp.		sll1900	acetyltransferase