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遺伝子 : Catechol 1,2-dioxygenase (CATA)

遺伝子情報

ID NRULE_0052
遺伝子ID CATA
作成日 2012/09/28
タンパク質名
Protein name
Full
Catechol 1,2-dioxygenase
EC
EC 1.13.11.1
遺伝子名 catA
遺伝子条件 TIGRFAMs; TIGR02439; hit=1
OR
TIGRFAMs; TIGR02438; hit=1
参照
Gene Ontology
GO
GO:0018576, F:catechol 1,2-dioxygenase activity, IDA:UniProtKB
GO:0008199, F:ferric iron binding, IDA:UniProtKB
GO:0042952, P:beta-ketoadipate pathway, IEA:UniProtKB-UniPathway
GO:0019614, P:catechol-containing compound catabolic process, IDA:UniProtKB
GO:0019439, P:aromatic compound catabolic process, IEA:UniProtKB-KW
Phylogenomic databases
eggNOG
COG3485, -
KO
K03381, -
ProtClustDB
CLSK867324, -
Enzyme and pathway databases
UniPathway
UPA00157, UER00258
Family and domain databases
InterPro
IPR007535, Catechol_dOase_N
IPR012801, Cchol_dOase_prob
IPR000627, Intradiol_dOase_C
IPR015889, Intradiol_dOase_core
IPR012800, Cchol_dOase_actb
Pfam
PF00775, Dioxygenase_C, 1
PF04444, Dioxygenase_N, 1
TIGRFAMs
TIGR02438, catachol_actin, 1
PROSITE
PS00083, INTRADIOL_DIOXYGENAS, 1
配列の特徴
P07773 Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1).
METAL164Iron.
METAL200Iron.
METAL224Iron.
METAL226Iron.
注釈
Catalytic activity
Catechol + O(2) = cis,cis-muconate
Cofactor
Binds 1 Fe(3+) ion per subunit
Pathway
Aromatic compound metabolism; beta-ketoadipate pathway; 5-oxo-4,5-dihydro-2-furylacetate from catechol: step 1/3
Subunit structure
Homodimer
Sequence similarities
Belongs to the intradiol ring-cleavage dioxygenase family
参考文献
P07773 Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1).
3170486
DNA sequence of the Acinetobacter calcoaceticus catechol 1,2-dioxygenase I structural gene catA: evidence for evolutionary divergence of intradiol dioxygenases by acquisition of DNA sequence repetitions. (J Bacteriol. 1988)
P95607 Rhodococcus opacus (Nocardia opaca).
8990288
Characterization of catechol catabolic genes from Rhodococcus erythropolis 1CP. (J Bacteriol. 1997)
20040374
Catechol 1,2-dioxygenase from the Gram-positive Rhodococcus opacus 1CP: quantitative structure/activity relationship and the crystal structures of native enzyme and catechols adducts. (J Struct Biol. 2010)



関与する機能

機能名
Catechol degradation (beta-ketoadipate pathway)

該当CDS

データダウンロード
学名 NBRC番号 CDS タンパク質名
Acinetobacter sp.100985ACT4_038_00470catechol 1,2-dioxygenase
Amycolatopsis azurea14573C791_4458Catechol 1,2-dioxygenase
Corynebacterium ammoniagenes12612HMPREF0281_01041catechol 1,2-dioxygenase
Corynebacterium callunae15359H924_10115catechol 1,2-dioxygenase
Corynebacterium efficiens100395CE2304putative catechol 1,2-dioxygenase
Corynebacterium glutamicum12168Cgl2402Protocatechuate 3,4-dioxygenase beta subunit
Corynebacterium glutamicum12153KIQ_00490catechol 1,2-dioxygenase
Cupriavidus metallidurans102507Rmet_1781Catechol 1,2-dioxygenase
Rmet_4881Catechol 1,2-dioxygenase
Enterobacter aerogenes13534EAE_19900catechol 1,2-dioxygenase
Escherichia fergusonii102419EFER_1481Catechol 1,2-dioxygenase (1,2-CTD)
Geodermatophilus obscurus13315Gobs_1294catechol 1,2-dioxygenase
Gordonia aichiensis108223GOACH_07_01280catechol 1,2-dioxygenase
Gordonia alkanivorans16433GOALK_038_00950catechol 1,2-dioxygenase
GOALK_047_00090catechol 1,2-dioxygenase
Gordonia amarae15530GOAMR_78_00330catechol 1,2-dioxygenase
Gordonia amicalis100051GOAMI_26_00200catechol 1,2-dioxygenase
GOAMI_40_00430catechol 1,2-dioxygenase
Gordonia bronchialis16047Gbro_4154catechol 1,2-dioxygenase
Gordonia namibiensis108229GONAM_24_00060catechol 1,2-dioxygenase
GONAM_25_00340catechol 1,2-dioxygenase
Gordonia otitidis100426GOOTI_181_00070catechol 1,2-dioxygenase
Gordonia polyisoprenivorans16320GOPIP_011_00810catechol 1,2-dioxygenase
Gordonia rhizosphera16068GORHZ_062_00750catechol 1,2-dioxygenase
Gordonia rubripertincta101908GORBP_060_00800catechol 1,2-dioxygenase
GORBP_108_00140catechol 1,2-dioxygenase
Gordonia sihwensis108236GSI01S_28_00230catechol 1,2-dioxygenase
Gordonia terrae100016GOTRE_125_00090catechol 1,2-dioxygenase
Marinomonas mediterranea103028Marme_3628catechol 1,2-dioxygenase
Pseudomonas putida100650PP_3166catechol 1,2-dioxygenase
PP_3713catechol 1,2-dioxygenase
Pseudomonas stutzeri14165PSTAB_1584catechol 1,2-dioxygenase
Rhodococcus erythropolis100887RER_54230catechol 1,2-dioxygenase
Rhodococcus opacus108011ROP_20870catechol 1,2-dioxygenase
ROP_22420catechol 1,2-dioxygenase
Saccharomonospora cyanea14841SaccyDRAFT_1682catechol 1,2-dioxygenase
Saccharomonospora viridis12207Svir_19220catechol 1,2-dioxygenase
Saccharopolyspora erythraea13426SACE_4382catechol 1,2-dioxygenase
Shimwellia blattae105725EB105725_23_00460catechol 1,2-dioxygenase
Sphingomonas wittichii105917Swit_0977catechol 1,2-dioxygenase
Streptomyces ghanaensis15414SSFG_07169catechol 1,2-dioxygenase