| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
Q9EWA1_9ACTO (Q9EWA1) |
|
|
0.0 |
18590 |
100% |
|
- Product
- PimS2 protein
- Gene
- pimS2
- Organism
- Streptomyces natalensis
|
1uniprot[Pubmed] 11094342 [Medline] 20547809 A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000] |
|
2
|
F1CLA9_9ACTO (F1CLA9) |
|
|
0.0 |
16590 |
93% |
|
- Product
- ScnS2
- Gene
- scnS2
- Organism
- Streptomyces chattanoogensis
|
1uniprot[Pubmed] 21330439 The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011] |
|
3
|
Q6W5P6_9ACTO (Q6W5P6) |
|
|
0.0 |
11490 |
67% |
|
- Product
- FscD
- Gene
- fscD
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
4
|
Q9L4X3_9ACTO (Q9L4X3) |
|
|
0.0 |
10530 |
63% |
|
- Product
- NysI
- Gene
- nysI
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
5
|
D2CKL5_PSEAH (D2CKL5) |
|
|
0.0 |
10250 |
62% |
|
- Product
- CppI
- Gene
- cppI
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 19697072 Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009] |
|
6
|
Q93NX9_9ACTO (Q93NX9) |
|
(10 hsp) |
0.0 |
8748 |
65% |
|
- Product
- AmphI
- Gene
- amphI
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|
7
|
Q1WEK7_9ACTO (Q1WEK7) |
|
(9 hsp) |
0.0 |
6504 |
51% |
|
- Product
- Polyketide synthase
- Gene
- merC
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
9
|
A0FCL3_STRVO (A0FCL3) |
|
(24 hsp) |
0.0 |
6311 |
51% |
|
- Product
- MerC
- Gene
- merC
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
10
|
D7C2C3_STRBB (D7C2C3) |
|
(7 hsp) |
0.0 |
5769 |
66% |
|
- Product
- Modular polyketide synthase
- Gene
- pks3-4
SBI_00656
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
11
|
Q93H84_STRAW (Q93H84) |
|
(7 hsp) |
0.0 |
5727 |
55% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA4
SAV416 SAV_416
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
12
|
Q52V44_9ACTO (Q52V44) |
|
(12 hsp) |
0.0 |
5422 |
55% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
13
|
D7C2C2_STRBB (D7C2C2) |
|
(7 hsp) |
0.0 |
5287 |
63% |
|
- Product
- Modular polyketide synthase
- Gene
- pks3-3
SBI_00655
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
15
|
E0D202_9ACTO (E0D202) |
|
(21 hsp) |
0.0 |
5004 |
52% |
|
- Product
- Polyketide synthase
- Gene
- gfsA
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
16
|
A0ACI0_STRAM (A0ACI0) |
|
(9 hsp) |
0.0 |
4886 |
51% |
|
- Product
- Putative modular polyketide synthase
- Gene
- SAMR0474
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
18
|
D7BRE1_STRBB (D7BRE1) |
|
(8 hsp) |
0.0 |
4506 |
53% |
|
- Product
- Modular polyketide synthase
- Gene
- SBI_01983
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
19
|
Q52V46_9ACTO (Q52V46) |
|
(11 hsp) |
0.0 |
4457 |
54% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
21
|
Q66VY5_STRRM (Q66VY5) |
|
(8 hsp) |
0.0 |
4367 |
78% |
|
- Product
- Rimocidin synthase
- Gene
- rms
- Organism
- Streptomyces rimosus
|
1uniprot Cloning and characterisation of type I polyketide synthase from an anti-fungal antibiotic producing Streptomyces rimosus. [2004] | 2uniprot Characterisation of type I polyketide synthase gene cluster from rimocidin-producing Streptomyces rimosus R7. [2004] |
|
22
|
Q6MZ72_MYCUA (Q6MZ72) |
|
(38 hsp) |
0.0 |
4331 |
45% |
|
- Product
- Type I modular polyketide synthase
- Gene
- mlsB
MUP032c
- Organism
- Mycobacterium ulcerans (strain Agy99)
|
1uniprot[Pubmed] 14736915 Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004] | 2uniprot[Pubmed] 15758215 Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005] | [pubmed all]
|
23
|
A0ACH1_STRAM (A0ACH1) |
|
(16 hsp) |
0.0 |
4200 |
52% |
|
- Product
- Putative polyketide synthase B
- Gene
- SAMR0465
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
24
|
B6CLY1_9MYCO (B6CLY1) |
|
(32 hsp) |
0.0 |
4181 |
45% |
|
- Product
- Type I modular polyketide synthase, MlsB
- Gene
- mlsB
MULP_051
- Organism
- Mycobacterium liflandii 128FXT
|
1uniprot[Pubmed] 18840298 Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008] |
|
25
|
Q9ALM3_9PSEU (Q9ALM3) |
|
(8 hsp) |
0.0 |
4158 |
52% |
|
- Product
- Polyketide synthase extender modules 5-7
- Gene
- spnD
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001] |
|
32
|
Q27W58_STRVO (Q27W58) |
|
(9 hsp) |
0.0 |
3987 |
50% |
|
- Product
- NigAVII
- Gene
-
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17584617 Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137.(Chem. Biol.) [2007] |
|
37
|
Q93HJ2_STRAW (Q93HJ2) |
|
(8 hsp) |
0.0 |
3789 |
50% |
|
- Product
- Modular polyketide synthase
- Gene
- olmA6
SAV2896 SAV_2896
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
38
|
Q3S864_9ACTO (Q3S864) |
|
(15 hsp) |
0.0 |
3774 |
55% |
|
- Product
- Nodular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
39
|
D3Y1I3_9ACTO (D3Y1I3) |
|
(21 hsp) |
0.0 |
3736 |
53% |
|
- Product
- TamAI
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
40
|
C9YYI1_STRSW (C9YYI1) |
|
(14 hsp) |
0.0 |
3731 |
55% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83901
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
41
|
A0ACH3_STRAM (A0ACH3) |
|
(21 hsp) |
0.0 |
3724 |
49% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SAMR0467
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
42
|
F1DI31_9ACTO (F1DI31) |
|
(21 hsp) |
0.0 |
3722 |
53% |
|
- Product
- TrdAI
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
43
|
Q1WEK8_9ACTO (Q1WEK8) |
|
(22 hsp) |
0.0 |
3701 |
52% |
|
- Product
- Polyketide synthase
- Gene
- merB
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
44
|
D1GLV9_9ACTO (D1GLV9) |
|
(20 hsp) |
0.0 |
3683 |
52% |
|
- Product
- Polyketide synthase type I
- Gene
- slgA1
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
45
|
C9YYI3_STRSW (C9YYI3) |
|
(13 hsp) |
0.0 |
3677 |
53% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83921
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
48
|
Q3S869_9ACTO (Q3S869) |
|
(15 hsp) |
0.0 |
3662 |
53% |
|
- Product
- Modular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
49
|
Q3S865_9ACTO (Q3S865) |
|
(9 hsp) |
0.0 |
3611 |
49% |
|
- Product
- Modular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
50
|
C0SMW4_9ACTO (C0SMW4) |
|
(38 hsp) |
0.0 |
3610 |
52% |
|
- Product
- Type I modular polyketide synthase
- Gene
- ttmJ
- Organism
- Streptomyces spiroverticillatus
|
1uniprot[Pubmed] 16707708 Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006] | 2uniprot[Pubmed] 18708355 Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008] | [pubmed all]
|
52
|
Q93HJ5_STRAW (Q93HJ5) |
|
(21 hsp) |
0.0 |
3596 |
54% |
|
- Product
- Modular polyketide synthase
- Gene
- olmA1
SAV2899 SAV_2899
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
53
|
D6C474_9ACTO (D6C474) |
|
(14 hsp) |
0.0 |
3592 |
53% |
|
- Product
- Modular polyketide synthase
- Gene
- meiA4
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12811466 [Medline] 22777186 Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003] | 2uniprot[Pubmed] 20348291 Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010] | [pubmed all]
|
54
|
C9YYI0_STRSW (C9YYI0) |
|
(8 hsp) |
0.0 |
3581 |
49% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83891
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
55
|
A0FCL2_STRVO (A0FCL2) |
|
(23 hsp) |
0.0 |
3549 |
51% |
|
- Product
- MerB
- Gene
- merB
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
56
|
B6ZIR3_STRPT (B6ZIR3) |
|
(22 hsp) |
0.0 |
3543 |
50% |
|
- Product
- Polyketide synthase
- Gene
- pldAII
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
57
|
A4KCE4_9ACTO (A4KCE4) |
|
(38 hsp) |
0.0 |
3539 |
52% |
|
- Product
- Tautomycetin biosynthetic PKS
- Gene
-
- Organism
- Streptomyces sp. CK4412
|
1uniprot[Pubmed] 17379718 Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007] |
|
58
|
C6ZCS1_9ACTO (C6ZCS1) |
|
(38 hsp) |
0.0 |
3537 |
52% |
|
- Product
- Type I modular polyketide synthase
- Gene
- ttnA
- Organism
- Streptomyces griseochromogenes
|
1uniprot[Pubmed] 19191560 Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009] |
|
60
|
E4NJF2_KITSK (E4NJF2) |
|
(13 hsp) |
0.0 |
3519 |
54% |
|
- Product
- Modular polyketide synthase BFAS2
- Gene
- bfmA2
KSE_73450
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
62
|
Q53840_SORCE (Q53840) |
|
(24 hsp) |
0.0 |
3480 |
48% |
|
- Product
- Soraphen polyketide synthase B
- Gene
- sorB
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 7601830 [Medline] 95325306 A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes.(J. Bacteriol.) [1995] | 2uniprot[Pubmed] 12039053 [Medline] 22035375 Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.(Gene) [2002] | [pubmed all]
|
64
|
B1W4J2_STRGG (B1W4J2) |
|
(16 hsp) |
0.0 |
3336 |
51% |
|
- Product
- Putative type-I PKS
- Gene
- pks2-2
SGR_6180
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
65
|
B1W485_STRGG (B1W485) |
|
(15 hsp) |
0.0 |
3333 |
50% |
|
- Product
- Putative type-I PKS
- Gene
- pks1-1
SGR_6073
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
66
|
A4F5C7_SORCE (A4F5C7) |
|
(13 hsp) |
0.0 |
3333 |
50% |
|
- Product
- Polyketide synthase
- Gene
- spiH
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 17317575 Spiroketal polyketide formation in Sorangium: Identification of the biosynthetic gene cluster for the highly cytotoxic spirangienes.(Chem. Biol.) [2007] |
|
69
|
Q93HJ4_STRAW (Q93HJ4) |
|
(16 hsp) |
0.0 |
3301 |
51% |
|
- Product
- Modular polyketide synthase
OlmA2 protein
- Gene
- olmA2
SAV2898 SAV_2898
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
71
|
D3U9Y8_9ACTO (D3U9Y8) |
|
(28 hsp) |
0.0 |
3277 |
52% |
|
- Product
- Type I polyketide synthase
- Gene
- sfaH
- Organism
- Streptomyces flaveolus
|
1uniprot Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010] |
|
74
|
D6C473_9ACTO (D6C473) |
|
(20 hsp) |
0.0 |
3179 |
47% |
|
- Product
- Modular polyketide synthase
- Gene
- meiA2
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12811466 [Medline] 22777186 Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003] | 2uniprot[Pubmed] 20348291 Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010] | [pubmed all]
|
75
|
E4NJF1_KITSK (E4NJF1) |
|
(24 hsp) |
0.0 |
3155 |
50% |
|
- Product
- Modular polyketide synthase BFAS1
- Gene
- bfmA1
KSE_73440
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
76
|
Q9L4W4_9ACTO (Q9L4W4) |
|
(7 hsp) |
0.0 |
3080 |
58% |
|
- Product
- NysB
- Gene
- nysB
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
78
|
Q52V45_9ACTO (Q52V45) |
|
(9 hsp) |
0.0 |
3073 |
55% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
79
|
Q9S0R7_STRAW (Q9S0R7) |
|
(23 hsp) |
0.0 |
3061 |
44% |
|
- Product
- Type I polyketide synthase AVES 2
- Gene
- aveA2
SAV939 SAV_939
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 10449723 [Medline] 99380548 Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999] | 2uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 3uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
80
|
Q93NW7_9ACTO (Q93NW7) |
|
(7 hsp) |
0.0 |
3060 |
57% |
|
- Product
- AmphB
- Gene
- amphB
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | 3uniprot[Pubmed] 20696392 Structural and functional analysis of A-type ketoreductases from the amphotericin modular polyketide synthase.(Structure) [2010] | [pubmed all]
|
84
|
Q68BG5_STRHA (Q68BG5) |
|
(14 hsp) |
0.0 |
2966 |
53% |
|
- Product
- Type I polyketide synthase
- Gene
- hlsA
- Organism
- Streptomyces halstedii
|
1uniprot Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004] |
|
88
|
Q52V51_9ACTO (Q52V51) |
|
(8 hsp) |
0.0 |
2939 |
55% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
90
|
Q93H83_STRAW (Q93H83) |
|
(8 hsp) |
0.0 |
2920 |
54% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA5
SAV415 SAV_415
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
92
|
F1CLC1_9ACTO (F1CLC1) |
|
(25 hsp) |
0.0 |
2906 |
61% |
|
- Product
- ScnS1
- Gene
- scnS1
- Organism
- Streptomyces chattanoogensis
|
1uniprot[Pubmed] 21330439 The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011] |
|
93
|
A4FH83_SACEN (A4FH83) |
|
(18 hsp) |
0.0 |
2903 |
53% |
|
- Product
- Type I modular polyketide synthase
- Gene
- SACE_4139
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
94
|
Q5VKR4_SACER (Q5VKR4) |
|
(18 hsp) |
0.0 |
2903 |
53% |
|
- Product
- Type I PKS
- Gene
- pkeAIII
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15925898 A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004] |
|
95
|
D7C2B8_STRBB (D7C2B8) |
|
(27 hsp) |
0.0 |
2876 |
60% |
|
- Product
- Type I modular polyketide synthase
- Gene
- pks3-2
SBI_00651
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
96
|
Q93NW6_9ACTO (Q93NW6) |
|
(41 hsp) |
0.0 |
2873 |
61% |
|
- Product
- AmphC
- Gene
- amphC
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|
97
|
D7BRD4_STRBB (D7BRD4) |
|
(41 hsp) |
0.0 |
2870 |
61% |
|
- Product
- Short-chain dehydrogenase/reductase SDR
- Gene
- SBI_01976
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
99
|
Q9X993_9ACTO (Q9X993) |
|
(25 hsp) |
0.0 |
2860 |
61% |
|
- Product
- PimS1 protein
Polyketide synthase
- Gene
- pimS1
- Organism
- Streptomyces natalensis
|
1uniprot[Pubmed] 10187796 [Medline] 99214571 The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999] | 2uniprot[Pubmed] 11094342 [Medline] 20547809 A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000] | [pubmed all]
|