| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
Q30CS2_STRAU (Q30CS2) |
|
|
0.0 |
4409 |
100% |
|
- Product
- LipPks1
- Gene
- lipPks1
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 16723573 Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006] |
|
2
|
B6ZIR2_STRPT (B6ZIR2) |
|
(10 hsp) |
0.0 |
1744 |
51% |
|
- Product
- Polyketide synthase
- Gene
- pldAI
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
3
|
Q68BG5_STRHA (Q68BG5) |
|
(6 hsp) |
0.0 |
1721 |
49% |
|
- Product
- Type I polyketide synthase
- Gene
- hlsA
- Organism
- Streptomyces halstedii
|
1uniprot Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004] |
|
5
|
D6C4C5_9ACTO (D6C4C5) |
|
(6 hsp) |
0.0 |
1663 |
48% |
|
- Product
- Modular polyketide synthase
- Gene
- meiA1
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12811466 [Medline] 22777186 Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003] | 2uniprot[Pubmed] 20348291 Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010] | [pubmed all]
|
6
|
D7C488_STRBB (D7C488) |
|
(6 hsp) |
0.0 |
1659 |
48% |
|
- Product
- Type I polyketide synthase
- Gene
- milA1
SBI_00789
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
7
|
E2Q521_STRCL (E2Q521) |
|
(9 hsp) |
0.0 |
1658 |
50% |
|
- Product
- Modular polyketide synthase
- Gene
- SCLAV_0015
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
8
|
D1GLV9_9ACTO (D1GLV9) |
|
(9 hsp) |
0.0 |
1640 |
50% |
|
- Product
- Polyketide synthase type I
- Gene
- slgA1
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
9
|
E4NJF1_KITSK (E4NJF1) |
|
(6 hsp) |
0.0 |
1631 |
52% |
|
- Product
- Modular polyketide synthase BFAS1
- Gene
- bfmA1
KSE_73440
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
13
|
D3Y1I3_9ACTO (D3Y1I3) |
|
(9 hsp) |
0.0 |
1587 |
48% |
|
- Product
- TamAI
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
15
|
F1DI31_9ACTO (F1DI31) |
|
(9 hsp) |
0.0 |
1579 |
47% |
|
- Product
- TrdAI
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
16
|
Q8KPW5_9ACTO (Q8KPW5) |
|
(6 hsp) |
0.0 |
1577 |
48% |
|
- Product
- Putative type I polyketide synthase
- Gene
- gerSI
- Organism
- Streptomyces sp. KCTC 0041BP
|
1uniprot[Pubmed] 17053005 Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007] | 2uniprot Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006] |
|
17
|
Q5SFB4_STRBI (Q5SFB4) |
|
(6 hsp) |
0.0 |
1575 |
48% |
|
- Product
- Polyketide synthase subunit
- Gene
- chmGI
- Organism
- Streptomyces bikiniensis
|
1uniprot[Pubmed] 15561847 Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.(Antimicrob. Agents Chemother.) [2004] |
|
18
|
A4FH85_SACEN (A4FH85) |
|
(7 hsp) |
0.0 |
1574 |
54% |
|
- Product
- Type I modular polyketide synthase
- Gene
- SACE_4141
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
19
|
Q5VKQ3_SACER (Q5VKQ3) |
|
(7 hsp) |
0.0 |
1574 |
54% |
|
- Product
- Type I PKS
- Gene
- pkeAI
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15925898 A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004] |
|
20
|
Q52V51_9ACTO (Q52V51) |
|
(4 hsp) |
0.0 |
1565 |
52% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
21
|
Q3S869_9ACTO (Q3S869) |
|
(8 hsp) |
0.0 |
1558 |
54% |
|
- Product
- Modular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
22
|
C5HV16_STRAT (C5HV16) |
|
(8 hsp) |
0.0 |
1557 |
54% |
|
- Product
- Polyketide synthase
- Gene
- idmN
- Organism
- Streptomyces antibioticus
|
1uniprot Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009] |
|
23
|
E0D202_9ACTO (E0D202) |
|
(12 hsp) |
0.0 |
1556 |
54% |
|
- Product
- Polyketide synthase
- Gene
- gfsA
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
24
|
Q1WEK9_9ACTO (Q1WEK9) |
|
(8 hsp) |
0.0 |
1554 |
48% |
|
- Product
- Polyketide synthase
- Gene
- merA
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
27
|
A0FCL1_STRVO (A0FCL1) |
|
(7 hsp) |
0.0 |
1551 |
48% |
|
- Product
- MerA
- Gene
- merA
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
28
|
C9YYI3_STRSW (C9YYI3) |
|
(8 hsp) |
0.0 |
1547 |
54% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83921
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
30
|
Q9ZGI5_9ACTO (Q9ZGI5) |
|
(6 hsp) |
0.0 |
1540 |
48% |
|
- Product
- Type I polyketide synthase PikAI
- Gene
- pikAI
- Organism
- Streptomyces venezuelae
|
1uniprot[Pubmed] 9770448 [Medline] 98445333 A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998] |
|
32
|
D7BRE1_STRBB (D7BRE1) |
|
(7 hsp) |
0.0 |
1535 |
54% |
|
- Product
- Modular polyketide synthase
- Gene
- SBI_01983
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
33
|
B1W485_STRGG (B1W485) |
|
(9 hsp) |
0.0 |
1532 |
55% |
|
- Product
- Putative type-I PKS
- Gene
- pks1-1
SGR_6073
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
34
|
F1DI32_9ACTO (F1DI32) |
|
(6 hsp) |
0.0 |
1531 |
55% |
|
- Product
- TrdAII
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
35
|
Q9KIV4_STRAT (Q9KIV4) |
|
(5 hsp) |
0.0 |
1530 |
46% |
|
- Product
- 8,8a-deoxyoleandolide synthase 1
- Gene
- oleAI
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 10908114 [Medline] 20363406 Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin.(J. Antibiot.) [2000] |
|
37
|
D3Y1I4_9ACTO (D3Y1I4) |
|
(6 hsp) |
0.0 |
1524 |
55% |
|
- Product
- TamAII
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
38
|
D1GLV8_9ACTO (D1GLV8) |
|
(6 hsp) |
0.0 |
1519 |
56% |
|
- Product
- Polyketide synthase type I
- Gene
- slgA2
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
39
|
Q83X69_STRRO (Q83X69) |
|
(5 hsp) |
0.0 |
1515 |
48% |
|
- Product
- Lankamycin synthase LkmAI
- Gene
- lkmAI
- Organism
- Streptomyces rochei
Streptomyces parvullus
|
1uniprot[Pubmed] 12791134 [Medline] 22676866 The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003] | 2uniprot[Pubmed] 10954087 [Medline] 20408175 Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000] | 3uniprot[Pubmed] 10767533 [Medline] 20231737 Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000] | 4uniprot[Pubmed] 9836424 [Medline] 99053144 Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998] | [pubmed all]
|
41
|
D8HZ82_AMYMU (D8HZ82) |
|
(6 hsp) |
0.0 |
1510 |
48% |
|
- Product
- Rifamycin polyketide synthase
- Gene
- rifA
AMED_0617
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
42
|
O54666_AMYMD (O54666) |
|
(6 hsp) |
0.0 |
1510 |
48% |
|
- Product
- RifA
Rifamycin polyketide synthase, type 1
- Gene
- rifA
- Organism
- Amycolatopsis mediterranei
Nocardia mediterranei
|
1uniprot[Pubmed] 9512878 [Medline] 98174059 Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998] | 2uniprot[Pubmed] 9497318 [Medline] 98165773 3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998] | 3uniprot[Pubmed] 11278540 [Medline] 21201076 Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001] | [pubmed all]
|
43
|
B1W487_STRGG (B1W487) |
|
(4 hsp) |
0.0 |
1505 |
52% |
|
- Product
- Putative type-I PKS
- Gene
- pks1-3
SGR_6075
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
44
|
Q9ALM6_9PSEU (Q9ALM6) |
|
(3 hsp) |
0.0 |
1504 |
46% |
|
- Product
- Polyketide synthase loading and extender module 1
- Gene
- spnA
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001] |
|
45
|
Q6W5P6_9ACTO (Q6W5P6) |
|
(13 hsp) |
0.0 |
1498 |
53% |
|
- Product
- FscD
- Gene
- fscD
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
46
|
Q9S0R8_STRAW (Q9S0R8) |
|
(8 hsp) |
0.0 |
1489 |
46% |
|
- Product
- Type I polyketide synthase AVES 1
- Gene
- aveA1
SAV938 SAV_938
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 10449723 [Medline] 99380548 Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999] | 2uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 3uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
47
|
D7CC08_STRBB (D7CC08) |
|
(8 hsp) |
0.0 |
1487 |
52% |
|
- Product
- Putative type I polyketide synthase
- Gene
- pks5-2
SBI_01382
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
48
|
Q1WEK8_9ACTO (Q1WEK8) |
|
(12 hsp) |
0.0 |
1485 |
52% |
|
- Product
- Polyketide synthase
- Gene
- merB
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
52
|
Q93NX9_9ACTO (Q93NX9) |
|
(12 hsp) |
0.0 |
1475 |
52% |
|
- Product
- AmphI
- Gene
- amphI
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|
53
|
B6ZIR3_STRPT (B6ZIR3) |
|
(12 hsp) |
0.0 |
1474 |
52% |
|
- Product
- Polyketide synthase
- Gene
- pldAII
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
55
|
Q9F830_9ACTO (Q9F830) |
|
(7 hsp) |
0.0 |
1472 |
46% |
|
- Product
- Megalomicin 6-deoxyerythronolide B synthase 1
- Gene
- megAI
- Organism
- Micromonospora megalomicea subsp. nigra
|
1uniprot[Pubmed] 10972798 [Medline] 20430101 Biosynthesis of the anti-parasitic agent megalomicin: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea.(Mol. Microbiol.) [2000] |
|
56
|
A0FCL2_STRVO (A0FCL2) |
|
(12 hsp) |
0.0 |
1469 |
51% |
|
- Product
- MerB
- Gene
- merB
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
57
|
A4F7N8_SACEN (A4F7N8) |
|
(4 hsp) |
0.0 |
1463 |
46% |
|
- Product
- EryAI Erythromycin polyketide synthase modules 1 and 2
- Gene
- eryAI
SACE_0721
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
58
|
Q5UNP6_SACER (Q5UNP6) |
|
(4 hsp) |
0.0 |
1463 |
46% |
|
- Product
- EryAI
- Gene
- eryAI
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15496466 Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2004] |
|
59
|
A4FH83_SACEN (A4FH83) |
|
(8 hsp) |
0.0 |
1454 |
51% |
|
- Product
- Type I modular polyketide synthase
- Gene
- SACE_4139
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
60
|
Q5VKR4_SACER (Q5VKR4) |
|
(8 hsp) |
0.0 |
1454 |
51% |
|
- Product
- Type I PKS
- Gene
- pkeAIII
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15925898 A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004] |
|
61
|
Q3S864_9ACTO (Q3S864) |
|
(8 hsp) |
0.0 |
1452 |
53% |
|
- Product
- Nodular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
63
|
Q93H83_STRAW (Q93H83) |
|
(5 hsp) |
0.0 |
1449 |
52% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA5
SAV415 SAV_415
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
64
|
D2CKL5_PSEAH (D2CKL5) |
|
(13 hsp) |
0.0 |
1447 |
52% |
|
- Product
- CppI
- Gene
- cppI
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 19697072 Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009] |
|
67
|
C9YYI1_STRSW (C9YYI1) |
|
(8 hsp) |
0.0 |
1441 |
55% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83901
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
68
|
ERYA1_SACER (Q03131) |
|
(6 hsp) |
0.0 |
1439 |
46% |
|
- Product
- Erythronolide synthase, modules 1 and 2
6-deoxyerythronolide B synthase I DEBS 1 ORF 1
- Gene
- eryA
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 2024119 [Medline] 91220065 Modular organization of genes required for complex polyketide biosynthesis.(Science) [1991] | 2uniprot[Pubmed] 8386127 [Medline] 93231529 IS1136, an insertion element in the erythromycin gene cluster of Saccharopolyspora erythraea.(Gene) [1993] | [pubmed all]
|
71
|
D3U9Y9_9ACTO (D3U9Y9) |
|
(6 hsp) |
0.0 |
1435 |
55% |
|
- Product
- Type I polyketide synthase
- Gene
- sfaI
- Organism
- Streptomyces flaveolus
|
1uniprot Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010] |
|
75
|
Q9L4X3_9ACTO (Q9L4X3) |
|
(13 hsp) |
0.0 |
1431 |
51% |
|
- Product
- NysI
- Gene
- nysI
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
76
|
Q93HJ2_STRAW (Q93HJ2) |
|
(6 hsp) |
0.0 |
1428 |
51% |
|
- Product
- Modular polyketide synthase
- Gene
- olmA6
SAV2896 SAV_2896
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
77
|
F1CLA9_9ACTO (F1CLA9) |
|
(13 hsp) |
0.0 |
1427 |
53% |
|
- Product
- ScnS2
- Gene
- scnS2
- Organism
- Streptomyces chattanoogensis
|
1uniprot[Pubmed] 21330439 The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011] |
|
78
|
Q82QT4_STRAW (Q82QT4) |
|
(13 hsp) |
0.0 |
1425 |
45% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA1
SAV419 SAV_419
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
79
|
Q93H87_STRAW (Q93H87) |
|
(10 hsp) |
0.0 |
1424 |
45% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA1
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
81
|
D7C2C3_STRBB (D7C2C3) |
|
(7 hsp) |
0.0 |
1421 |
53% |
|
- Product
- Modular polyketide synthase
- Gene
- pks3-4
SBI_00656
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
82
|
B6ZIR4_STRPT (B6ZIR4) |
|
(6 hsp) |
0.0 |
1421 |
55% |
|
- Product
- Polyketide synthase
- Gene
- pldAIII
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
84
|
E4NJF2_KITSK (E4NJF2) |
|
(8 hsp) |
0.0 |
1419 |
55% |
|
- Product
- Modular polyketide synthase BFAS2
- Gene
- bfmA2
KSE_73450
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
85
|
Q30CS1_STRAU (Q30CS1) |
|
(7 hsp) |
0.0 |
1418 |
82% |
|
- Product
- LipPks2
- Gene
- lipPks2
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 16723573 Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006] |
|
86
|
Q1WEK7_9ACTO (Q1WEK7) |
|
(11 hsp) |
0.0 |
1416 |
52% |
|
- Product
- Polyketide synthase
- Gene
- merC
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
87
|
Q52V47_9ACTO (Q52V47) |
|
(3 hsp) |
0.0 |
1415 |
51% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
90
|
F1CT51_9ACTO (F1CT51) |
|
(9 hsp) |
0.0 |
1404 |
49% |
|
- Product
- GdmAI
- Gene
- gdmAI
- Organism
- Streptomyces autolyticus
|
1uniprot[Pubmed] 21544574 Streptomyces autolyticus JX-47 Large-Insert Bacterial Artificial Chromosome Library Construction and Identification of Clones Covering Geldanamycin Biosynthesis Gene Cluster.(Curr. Microbiol.) [2011] |
|
91
|
B1W490_STRGG (B1W490) |
|
(4 hsp) |
0.0 |
1404 |
54% |
|
- Product
- Putative type-I PKS
- Gene
- pks1-6
SGR_6078
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
92
|
Q9EWA1_9ACTO (Q9EWA1) |
|
(13 hsp) |
0.0 |
1404 |
53% |
|
- Product
- PimS2 protein
- Gene
- pimS2
- Organism
- Streptomyces natalensis
|
1uniprot[Pubmed] 11094342 [Medline] 20547809 A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000] |
|
94
|
A4F5C6_SORCE (A4F5C6) |
|
(7 hsp) |
0.0 |
1402 |
51% |
|
- Product
- Polyketide synthase
- Gene
- spiG
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 17317575 Spiroketal polyketide formation in Sorangium: Identification of the biosynthetic gene cluster for the highly cytotoxic spirangienes.(Chem. Biol.) [2007] |
|
95
|
Q76KZ4_STRHA (Q76KZ4) |
|
(5 hsp) |
0.0 |
1402 |
48% |
|
- Product
- Polyketide synthase modules 5-6
- Gene
- vinP3
- Organism
- Streptomyces halstedii
|
1uniprot[Pubmed] 15112997 Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004] |
|
96
|
Q53840_SORCE (Q53840) |
|
(13 hsp) |
0.0 |
1402 |
51% |
|
- Product
- Soraphen polyketide synthase B
- Gene
- sorB
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 7601830 [Medline] 95325306 A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes.(J. Bacteriol.) [1995] | 2uniprot[Pubmed] 12039053 [Medline] 22035375 Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.(Gene) [2002] | [pubmed all]
|
97
|
B1W488_STRGG (B1W488) |
|
(3 hsp) |
0.0 |
1401 |
51% |
|
- Product
- Putative type-I PKS
- Gene
- pks1-4
SGR_6076
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
98
|
Q1L0T2_STRHY (Q1L0T2) |
|
(9 hsp) |
0.0 |
1401 |
48% |
|
- Product
- GelA
- Gene
-
- Organism
- Streptomyces hygroscopicus subsp. duamyceticus
|
1uniprot[Pubmed] 18600054 Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008] |
|
99
|
O33954_STRFR (O33954) |
|
(7 hsp) |
0.0 |
1399 |
47% |
|
- Product
- Tylactone synthase starter module and modules 1 & 2
- Gene
- tylG
- Organism
- Streptomyces fradiae
Streptomyces roseoflavus
|
1uniprot[Pubmed] 17719489 A tylosin ketoreductase reveals how chirality is determined in polyketides.(Chem. Biol.) [2007] |
|