| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
O52825_AMYOR (O52825) |
|
|
1e-81 |
305 |
100% |
|
- Product
- PCZA361.27
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 9545426 [Medline] 98212597 Sequencing and analysis of genes involved in the biosynthesis of a vancomycin group antibiotic.(Chem. Biol.) [1998] |
|
3
|
O87675_9PSEU (O87675) |
|
|
6e-48 |
194 |
85% |
|
- Product
- P450 monooxygenase
- Gene
- oxyC
- Organism
- Amycolatopsis balhimycina
|
1uniprot[Pubmed] 10390204 [Medline] 99318579 Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908.(Antimicrob. Agents Chemother.) [1999] | 2uniprot[Pubmed] 11932455 [Medline] 21930292 Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules.(Microbiology) [2002] | 3uniprot[Pubmed] 11495926 [Medline] 21486455 A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.(J. Biol. Chem.) [2001] | 4uniprot[Pubmed] 12404385 The biosynthesis of vancomycin-type glycopeptide antibiotics - the order of cyclization steps.(Angew. Chem. Int. Ed. Engl.) [2001] | 5uniprot[Pubmed] 11880037 [Medline] 21869276 Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.(Chem. Biol.) [2002] | 6uniprot Precursor-directed biosynthesis for the generation of novel glycopetides.(Ernst Schering Res. Found. Workshop) [2005] | [pubmed all]
|
4
|
C5C4_AMYOR (Q8RN03) |
|
|
1e-47 |
192 |
84% |
|
- Product
- Cytochrome P450 165C4
Vancomycin biosynthesis protein OxyC
- Gene
- CYP165C4
oxyC
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 12207020 [Medline] 22344604 Crystal structure of OxyB, a cytochrome P450 implicated in an oxidative phenol coupling reaction during vancomycin biosynthesis.(J. Biol. Chem.) [2002] | 2uniprot[Pubmed] 12888556 Crystal structure of OxyC, a cytochrome P450 implicated in an oxidative C-C coupling reaction during vancomycin biosynthesis.(J. Biol. Chem.) [2003] | [pubmed all]
|
5
|
B7T1C5_9BACT (B7T1C5) |
|
|
4e-44 |
181 |
77% |
|
- Product
- Veg12
- Gene
- veg12
- Organism
- uncultured soil bacterium
|
1uniprot[Pubmed] 18987322 Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008] |
|
6
|
E9L1L7_9ZZZZ (E9L1L7) |
|
|
5e-37 |
157 |
69% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA878-18
- Organism
- uncultured organism CA878
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
7
|
B7T1E0_9BACT (B7T1E0) |
|
|
3e-34 |
148 |
63% |
|
- Product
- Teg15
- Gene
- teg15
- Organism
- uncultured soil bacterium
|
1uniprot[Pubmed] 18987322 Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008] |
|
8
|
Q7WZ80_9ACTO (Q7WZ80) |
|
|
3e-32 |
142 |
67% |
|
- Product
- Putative oxygenase OxyC
- Gene
- dbv11
- Organism
- Nonomuraea sp. ATCC 39727
|
1uniprot[Pubmed] 12837387 [Medline] 22721464 The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003] |
|
9
|
E9L1I1_9ZZZZ (E9L1I1) |
|
|
2e-31 |
138 |
60% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA37-37
- Organism
- uncultured organism CA37
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
10
|
E9L1S6_9ZZZZ (E9L1S6) |
|
|
3e-31 |
138 |
55% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA915-34
- Organism
- uncultured organism CA915
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
11
|
Q6ZZI4_ACTTI (Q6ZZI4) |
|
|
2e-30 |
135 |
58% |
|
- Product
- P450 monooxygenase
- Gene
-
- Organism
- Actinoplanes teichomyceticus
|
1uniprot[Pubmed] 15113000 Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase.(Chem. Biol.) [2004] |
|
12
|
Q70AY6_ACTTI (Q70AY6) |
|
|
3e-26 |
121 |
63% |
|
- Product
- OxyC protein
- Gene
- tcp22
- Organism
- Actinoplanes teichomyceticus
|
1uniprot[Pubmed] 14702401 Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.(Microbiology) [2004] |
|
13
|
Q8KLM1_STRTO (Q8KLM1) |
|
|
8e-26 |
120 |
63% |
|
- Product
- StaJ
- Gene
-
- Organism
- Streptomyces toyocaensis
|
1uniprot[Pubmed] 9177243 [Medline] 97322398 D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB.(Proc. Natl. Acad. Sci. U.S.A.) [1997] | 2uniprot[Pubmed] 12060705 [Medline] 22080153 Assembling the glycopeptide antibiotic scaffold: the biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009.(Proc. Natl. Acad. Sci. U.S.A.) [2002] | [pubmed all]
|
14
|
O52816_AMYOR (O52816) |
|
|
2e-14 |
82.8 |
100% |
|
- Product
- PCZA361.27
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 9545426 [Medline] 98212597 Sequencing and analysis of genes involved in the biosynthesis of a vancomycin group antibiotic.(Chem. Biol.) [1998] |
|
15
|
Q93N81_STRLA (Q93N81) |
|
|
2e-08 |
62.8 |
42% |
|
- Product
- P450-related oxidase
- Gene
-
- Organism
- Streptomyces lavendulae
|
1uniprot[Pubmed] 11447274 [Medline] 21353013 Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
17
|
Q26591_SCHMA (Q26591) |
|
(6 hsp) |
2e-07 |
58.9 |
34% |
|
- Product
- P48 eggshell protein
- Gene
-
- Organism
- Schistosoma mansoni
Blood fluke
|
1uniprot[Pubmed] 1625706 [Medline] 92326866 Schistosoma mansoni p48 eggshell protein gene: characterization, developmentally regulated expression and comparison to the p14 eggshell protein gene.(Mol. Biochem. Parasitol.) [1992] |
|
18
|
B7T1D6_9BACT (B7T1D6) |
|
|
3e-07 |
58.5 |
41% |
|
- Product
- Teg11
- Gene
- teg11
- Organism
- uncultured soil bacterium
|
1uniprot[Pubmed] 18987322 Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008] |
|
19
|
Q8KLL9_STRTO (Q8KLL9) |
|
|
4e-07 |
58.2 |
38% |
|
- Product
- StaH
- Gene
-
- Organism
- Streptomyces toyocaensis
|
1uniprot[Pubmed] 9177243 [Medline] 97322398 D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB.(Proc. Natl. Acad. Sci. U.S.A.) [1997] | 2uniprot[Pubmed] 12060705 [Medline] 22080153 Assembling the glycopeptide antibiotic scaffold: the biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009.(Proc. Natl. Acad. Sci. U.S.A.) [2002] | [pubmed all]
|
20
|
E9L1I0_9ZZZZ (E9L1I0) |
|
|
2e-06 |
56.2 |
39% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA37-36
- Organism
- uncultured organism CA37
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
21
|
Q70AY8_ACTTI (Q70AY8) |
|
|
4e-06 |
55.1 |
38% |
|
- Product
- OxyB protein
- Gene
- tcp20
- Organism
- Actinoplanes teichomyceticus
|
1uniprot[Pubmed] 14702401 Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.(Microbiology) [2004] |
|
22
|
F4RDB2_MELLP (F4RDB2) |
|
|
4e-06 |
54.7 |
37% |
|
- Product
- Putative uncharacterized protein
- Gene
- MELLADRAFT_95813
- Organism
- Melampsora larici-populina (strain 98AG31 / pathotype 3-4-7)
Poplar leaf rust fungus
|
1uniprot[Pubmed] 21536894 Obligate biotrophy features unraveled by the genomic analysis of rust fungi.(Proc. Natl. Acad. Sci. U.S.A.) [2011] |
|
23
|
C7TZI4_SCHJA (C7TZI4) |
|
|
5e-06 |
54.7 |
27% |
|
- Product
- Stress protein DDR48 (DNA damage-responsive protein 48)
- Gene
-
- Organism
- Schistosoma japonicum
Blood fluke
|
1uniprot The Schistosoma japonicum genome reveals features of host-parasite interplay.(Nature) [2009] |
|
24
|
Q7WZ79_9ACTO (Q7WZ79) |
|
|
7e-06 |
54.3 |
38% |
|
- Product
- Putative OxyB monooxigenase
- Gene
- dbv12
- Organism
- Nonomuraea sp. ATCC 39727
|
1uniprot[Pubmed] 12837387 [Medline] 22721464 The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003] |
|
25
|
EGGS_SCHMA (P08016) |
|
|
8e-06 |
53.9 |
32% |
|
- Product
- Putative eggshell protein
- Gene
-
- Organism
- Schistosoma mansoni
Blood fluke
|
1uniprot[Pubmed] 3100949 [Medline] 87115624 Possible eggshell protein gene from Schistosoma mansoni.(Mol. Biochem. Parasitol.) [1987] |
|
26
|
Q7RE70_PLAYO (Q7RE70) |
|
(2 hsp) |
9e-06 |
53.9 |
53% |
|
- Product
- Putative uncharacterized protein PY05197
- Gene
- PY05197
- Organism
- Plasmodium yoelii yoelii
|
1uniprot[Pubmed] 12368865 [Medline] 22255706 Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii.(Nature) [2002] |
|
27
|
E9L1S5_9ZZZZ (E9L1S5) |
|
|
9e-06 |
53.9 |
37% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA915-33
- Organism
- uncultured organism CA915
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
28
|
F2Y371_9PHYC (F2Y371) |
|
(8 hsp) |
1e-05 |
53.5 |
54% |
|
- Product
- Putative uncharacterized protein
- Gene
- 162309597
- Organism
- Organic Lake phycodnavirus
|
1uniprot[Pubmed] 21444812 Virophage control of antarctic algal host-virus dynamics.(Proc. Natl. Acad. Sci. U.S.A.) [2011] |
|
29
|
A5K8V8_PLAVS (A5K8V8) |
|
(2 hsp) |
3e-05 |
52 |
57% |
|
- Product
- Kinesin motor domain containing protein
- Gene
- PVX_101175
- Organism
- Plasmodium vivax (strain Salvador I)
|
1uniprot[Pubmed] 18843361 Comparative genomics of the neglected human malaria parasite Plasmodium vivax.(Nature) [2008] |
|
30
|
B5MD94_HUMAN (B5MD94) |
|
(3 hsp) |
4e-05 |
51.6 |
44% |
|
- Product
- Uncharacterized protein
- Gene
- QRICH2
- Organism
- Homo sapiens
Human
|
1uniprot[Pubmed] 16625196 DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.(Nature) [2006] |
|
31
|
QRIC2_HUMAN (Q9H0J4) |
|
(4 hsp) |
4e-05 |
51.6 |
44% |
|
- Product
- Glutamine-rich protein 2
- Gene
- QRICH2
- Organism
- Homo sapiens
Human
|
1uniprot[Pubmed] 11230166 [Medline] 21154917 Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.(Genome Res.) [2001] | 2uniprot[Pubmed] 15489334 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).(Genome Res.) [2004] | 3uniprot[Pubmed] 14702039 Complete sequencing and characterization of 21,243 full-length human cDNAs.(Nat. Genet.) [2004] | [pubmed all]
|
32
|
Q5DHK3_SCHJA (Q5DHK3) |
|
(3 hsp) |
5e-05 |
51.2 |
37% |
|
- Product
- SJCHGC00913 protein
- Gene
-
- Organism
- Schistosoma japonicum
Blood fluke
|
1uniprot[Pubmed] 16617374 New perspectives on host-parasite interplay by comparative transcriptomic and proteomic analyses of Schistosoma japonicum.(PLoS Pathog.) [2006] |
|
33
|
Q5DEJ5_SCHJA (Q5DEJ5) |
|
(3 hsp) |
7e-05 |
50.8 |
37% |
|
- Product
- SJCHGC02037 protein
- Gene
-
- Organism
- Schistosoma japonicum
Blood fluke
|
1uniprot[Pubmed] 16617374 New perspectives on host-parasite interplay by comparative transcriptomic and proteomic analyses of Schistosoma japonicum.(PLoS Pathog.) [2006] |
|
34
|
E5APW4_BURRH (E5APW4) |
|
(2 hsp) |
8e-05 |
50.8 |
37% |
|
- Product
- Putative uncharacterized protein
- Gene
- RBRH_02277
- Organism
- Burkholderia rhizoxinica (strain DSM 19002 / CIP 109453 / HKI 454)
|
1uniprot[Pubmed] 21131495 Complete genome sequence of Burkholderia rhizoxinica, an endosymbiont of Rhizopus microsporus.(J. Bacteriol.) [2011] |
|
35
|
A5K0S5_PLAVS (A5K0S5) |
|
(3 hsp) |
8e-05 |
50.8 |
39% |
|
- Product
- Putative uncharacterized protein
- Gene
- PVX_084915
- Organism
- Plasmodium vivax (strain Salvador I)
|
1uniprot[Pubmed] 18843361 Comparative genomics of the neglected human malaria parasite Plasmodium vivax.(Nature) [2008] |
|
36
|
Q5DHX9_SCHJA (Q5DHX9) |
|
|
0.0001 |
50.4 |
33% |
|
- Product
- SJCHGC02035 protein
- Gene
-
- Organism
- Schistosoma japonicum
Blood fluke
|
1uniprot[Pubmed] 16617374 New perspectives on host-parasite interplay by comparative transcriptomic and proteomic analyses of Schistosoma japonicum.(PLoS Pathog.) [2006] |
|
37
|
F7EXS7_MACMU (F7EXS7) |
|
(3 hsp) |
0.0001 |
50.1 |
50% |
|
- Product
- Uncharacterized protein
- Gene
- QRICH2
- Organism
- Macaca mulatta
Rhesus macaque
|
1uniprot[Pubmed] 17431167 Evolutionary and biomedical insights from the rhesus macaque genome.(Science) [2007] |
|
38
|
B3L089_PLAKH (B3L089) |
|
(2 hsp) |
0.0001 |
49.7 |
38% |
|
- Product
- Putative uncharacterized protein
- Gene
- PKH_031370
- Organism
- Plasmodium knowlesi (strain H)
|
1uniprot[Pubmed] 18843368 The genome of the simian and human malaria parasite Plasmodium knowlesi.(Nature) [2008] |
|
40
|
D2HD63_AILME (D2HD63) |
|
|
0.0002 |
48.9 |
46% |
|
- Product
- Putative uncharacterized protein
- Gene
- PANDA_008599
- Organism
- Ailuropoda melanoleuca
Giant panda
|
1uniprot[Pubmed] 20010809 The sequence and de novo assembly of the giant panda genome.(Nature) [2010] |
|
41
|
C4Q136_SCHMA (C4Q136) |
|
(2 hsp) |
0.0003 |
48.9 |
36% |
|
- Product
- Putative uncharacterized protein
- Gene
- Smp_014610
- Organism
- Schistosoma mansoni
Blood fluke
|
1uniprot The genome of the blood fluke Schistosoma mansoni.(Nature) [2009] |
|
42
|
Q5DG07_SCHJA (Q5DG07) |
|
|
0.0003 |
48.9 |
37% |
|
- Product
- SJCHGC09509 protein
- Gene
-
- Organism
- Schistosoma japonicum
Blood fluke
|
1uniprot[Pubmed] 16617374 New perspectives on host-parasite interplay by comparative transcriptomic and proteomic analyses of Schistosoma japonicum.(PLoS Pathog.) [2006] |
|
44
|
Q5DDR5_SCHJA (Q5DDR5) |
|
|
0.0003 |
48.5 |
37% |
|
- Product
- SJCHGC02036 protein
- Gene
-
- Organism
- Schistosoma japonicum
Blood fluke
|
1uniprot[Pubmed] 16617374 New perspectives on host-parasite interplay by comparative transcriptomic and proteomic analyses of Schistosoma japonicum.(PLoS Pathog.) [2006] |
|
45
|
A4FI45_SACEN (A4FI45) |
|
|
0.0006 |
47.8 |
52% |
|
- Product
- Putative uncharacterized protein
- Gene
- SACE_4451
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
46
|
O87674_9PSEU (O87674) |
|
|
0.0006 |
47.8 |
34% |
|
- Product
- P450 monooxygenase
- Gene
- oxyB
- Organism
- Amycolatopsis balhimycina
|
1uniprot[Pubmed] 10390204 [Medline] 99318579 Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908.(Antimicrob. Agents Chemother.) [1999] | 2uniprot[Pubmed] 11932455 [Medline] 21930292 Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules.(Microbiology) [2002] | 3uniprot[Pubmed] 11495926 [Medline] 21486455 A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.(J. Biol. Chem.) [2001] | 4uniprot[Pubmed] 12404385 The biosynthesis of vancomycin-type glycopeptide antibiotics - the order of cyclization steps.(Angew. Chem. Int. Ed. Engl.) [2001] | 5uniprot[Pubmed] 11880037 [Medline] 21869276 Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.(Chem. Biol.) [2002] | 6uniprot Precursor-directed biosynthesis for the generation of novel glycopetides.(Ernst Schering Res. Found. Workshop) [2005] | [pubmed all]
|
47
|
C5B3_AMYOR (Q8RN04) |
|
|
0.0006 |
47.8 |
35% |
|
- Product
- Cytochrome P450 165B3
Vancomycin biosynthesis protein OxyB
- Gene
- CYP165B3
oxyB
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 12207020 [Medline] 22344604 Crystal structure of OxyB, a cytochrome P450 implicated in an oxidative phenol coupling reaction during vancomycin biosynthesis.(J. Biol. Chem.) [2002] |
|
48
|
E9L1H9_9ZZZZ (E9L1H9) |
|
|
0.0008 |
47.4 |
36% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA37-35
- Organism
- uncultured organism CA37
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
49
|
B3LCV0_PLAKH (B3LCV0) |
|
|
0.0008 |
47.4 |
53% |
|
- Product
- Protease, putative
- Gene
- PKH_144780
- Organism
- Plasmodium knowlesi (strain H)
|
1uniprot[Pubmed] 18843368 The genome of the simian and human malaria parasite Plasmodium knowlesi.(Nature) [2008] |
|
50
|
F7CG37_HORSE (F7CG37) |
|
|
0.0009 |
47.4 |
43% |
|
- Product
- Uncharacterized protein
- Gene
- LOC100058952
- Organism
- Equus caballus
Horse
|
1uniprot[Pubmed] 19892987 Genome sequence, comparative analysis, and population genetics of the domestic horse.(Science) [2009] |
|