Substance Data

Chemical Substances Information

CAS RN MITI Number Chemical Substance Name Chemical Structure
13463-41-7 5-3725 Pyrithione zinc


Regulatory Classification

Regulatory Classification Cabinet Order No./Registration No. Chemical Substance Name date Remarks
Priority Assessment Chemical Substances (PACSs)  139  (T-4)-Bis[2-(thioxo-kappaS)-pyridin-1(2H)-olato-kappaO]zinc(II)  2012/12/21   
Existing chemical substances  -  Zinc 2-pyridinethiol-1-oxide     


Screening Info

Publication year Human health effect Ecological effect Detailed assessment by experts Remarks
Exposure Class Hazard Class Priority Exposure Class Hazard Class Priority
2021 4 2 Medium - - - Assessment has been conducted by the serial number of Priority Assessment Chemical Substances (PACSs).
2012 3 - - 3 1 High Assessment has been conducted by the CAS RN.


Remarks


Information of Priority Assessment Chemical Substance

Information of designation

Classification Designated date No. MITI No. Name of Priority Assessment Chemical Substance Rationale for designation Remarks
PACS  2012/12/21  139  5-3725  (T-4)-Bis[2-(thioxo-kappaS)-pyridin-1(2H)-olato-kappaO]zinc(II) 
Human health effect:x(2021/12/16)
Ecological effect:x
detailed assessment by experts for:Human health effect(2021/12/16)


No. 139

Risk Assessment Phase 1-I

publication date Status of risk assessment publication source Remarks
2024/04/01 Risk Assessment Phase 1-I (human health effect)
2023/04/01 Risk Assessment Phase 1-I (human health effect)
2022/04/01 Risk Assessment Phase 1-I (human health effect)
2014/07/31 Risk Assessment Phase 1-II (ecological effect)

Risk Assessment Phase 1-Ⅱ, 1-Ⅲ

publication date Status of risk assessment publication source Remarks
2024/04/01 Risk Assessment Phase 1-II (ecological effect)
2023/04/01 Risk Assessment Phase 1-II (ecological effect)
2022/04/01 Risk Assessment Phase 1-II (ecological effect)
2021/04/01 Risk Assessment Phase 1-II (ecological effect)
2020/04/01 Risk Assessment Phase 1-II (ecological effect)
2019/04/01 Risk Assessment Phase 1-II (ecological effect)
2018/03/22 Risk Assessment Phase 1-II (ecological effect)
2016/12/27 Risk Assessment Phase 1-II (ecological effect)






Manufactured and/or imported quantities

Fiscal year MITI Number Registration No. Chemical Substance Name Classification Manufactured and/or imported quantities (t) Remarks
2022 5-3725 139 (T-4)-Bis[2-(thioxo-kappaS)-pyridin-1(2H)-olato-kappaO]zinc(II) Priority Assessment Chemical Substances (PACSs) 335 MITI number: 5-3725, 9-1110
2021 5-3725 139 (T-4)-Bis[2-(thioxo-kappaS)-pyridin-1(2H)-olato-kappaO]zinc(II) Priority Assessment Chemical Substances (PACSs) 562 MITI number: 5-3725, 9-1110
2020 5-3725 139 (T-4)-Bis[2-(thioxo-kappaS)-pyridin-1(2H)-olato-kappaO]zinc(II) Priority Assessment Chemical Substances (PACSs) 653 MITI number: 5-3725, 9-1110
2019 5-3725 139 (T-4)-Bis[2-(thioxo-kappaS)-pyridin-1(2H)-olato-kappaO]zinc(II) Priority Assessment Chemical Substances (PACSs) 609 MITI number: 5-3725, 9-1110
2018 5-3725 139 (T-4)-Bis[2-(thioxo-kappaS)-pyridin-1(2H)-olato-kappaO]zinc(II) Priority Assessment Chemical Substances (PACSs) 962 MITI number: 5-3725, 9-1110
2017 5-3725 139 (T-4)-Bis[2-(thioxo-kappaS)-pyridin-1(2H)-olato-kappaO]zinc(II) Priority Assessment Chemical Substances (PACSs) 1,099 MITI number: 5-3725, 9-1110
2016 5-3725 139 (T-4)-Bis[2-(thioxo-kappaS)-pyridin-1(2H)-olato-kappaO]zinc(II) Priority Assessment Chemical Substances (PACSs) 984 MITI number: 5-3725, 9-1110
2015 5-3725 139 (T-4)-Bis[2-(thioxo-kappaS)-pyridin-1(2H)-olato-kappaO]zinc(II) Priority Assessment Chemical Substances (PACSs) 851 MITI number: 5-3725, 9-1110
2014 5-3725 139 (T-4)-Bis[2-(thioxo-kappaS)-pyridin-1(2H)-olato-kappaO]zinc(II) Priority Assessment Chemical Substances (PACSs) 905 MITI number: 5-3725, 9-1110
2013 5-3725 139 (T-4)-Bis[2-(thioxo-kappaS)-pyridin-1(2H)-olato-kappaO]zinc(II) Priority Assessment Chemical Substances (PACSs) 779 MITI number: 5-3725, 9-1110
2012 5-3725 139 (T-4)-Bis[2-(thioxo-kappaS)-pyridin-1(2H)-olato-kappaO]zinc(II) Priority Assessment Chemical Substances (PACSs) 882 MITI number: 5-3725, 9-1110


Published information

publication source publication date Chemical Substance Name Published Result Judgement Remarks
Official Bulletin of Economy, Trade and Industry 2004/11/15 bis(2-sulfido-kappaS-pyridinio-1-olato-kappaO)zinc(II) (synonym:pyrithione zinc) Chemical substance determinated to be persistent but not highly bioaccumulative
Official Bulletin of Economy, Trade and Industry 2003/01/17 bis(2-sulfido-kappaS-pyridinio-1-olato-kappaO)zinc (synonym:pyrithione zinc) Chemical substance determinated to be persistent


Remarks 

Safety Test Results [METI] (PDF)
Data Sheet of Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test (TG422)
Summary Report of Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test (TG422)
Final Report of Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test (TG422) (in Japanese)


Test data    If you need test report(s)(Japanese only), please visit J-CHECK Japanese site.


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