Substance Data

Chemical Substances Information

CAS RN MITI Number Chemical Substance Name Chemical Structure
1643-20-5 2-198 1-Dodecanamine, N,N-dimethyl-, N-oxide


Regulatory Classification

Regulatory Classification Cabinet Order No./Registration No. Chemical Substance Name date Remarks
Priority Assessment Chemical Substances (PACSs)  169  N,N-Dimethylalkan-1-amine oxide (C=10,12,14,16,18, normal chain), (Z)-N,N-dimethyloctadec-9-en-1-amine oxide or (9Z,12Z)-N,N-dimethyloctadeca-9,12-dien-1-amine oxide  2014/04/01   
Canceled - Priority Assessment Chemical Substances  101  N,N-Dimethyldodecylamine N-oxide  2014/04/01  It is currently included in PACSs No. 169 (N,N-Dimethylalkan-1-amine oxide (C=10,12,14,16,18, normal chain), (Z)-N,N-dimethyloctadec-9-en-1-amine oxide or (9Z,12Z)-N,N-dimethyloctadeca-9,12-dien-1-amine oxide). 
Existing chemical substances  -  Alkyl (or alkenyl, at least one of the alkyl or alkenyl groups is C8-24,others are C1-5) amine oxide     


Screening Info

Publication year Human health effect Ecological effect Detailed assessment by experts Remarks
Exposure Class Hazard Class Priority Exposure Class Hazard Class Priority
2012 4 - - 4 1 High Assessment has been conducted by the CAS RN.


Remarks


Information of Priority Assessment Chemical Substance

Information of designation

Classification Designated date No. MITI No. Name of Priority Assessment Chemical Substance Rationale for designation Remarks
PACS  2014/04/01  169  2-198  N,N-Dimethylalkan-1-amine oxide (C=10,12,14,16,18, normal chain), (Z)-N,N-dimethyloctadec-9-en-1-amine oxide or (9Z,12Z)-N,N-dimethyloctadeca-9,12-dien-1-amine oxide 
Human health effect:
Ecological effect:x
detailed assessment by experts for:
Canceled PACS  2014/04/01  101  2-198  N,N-Dimethyldodecylamine N-oxide It is currently included in PACSs No. 169 (N,N-Dimethylalkan-1-amine oxide (C=10,12,14,16,18, normal chain), (Z)-N,N-dimethyloctadec-9-en-1-amine oxide or (9Z,12Z)-N,N-dimethyloctadeca-9,12-dien-1-amine oxide).
PACS  2012/12/21  101  2-198  N,N-Dimethyldodecylamine N-oxide 
Human health effect:
Ecological effect:x
detailed assessment by experts for:


No. 169

Risk Assessment Phase 1-I

publication date Status of risk assessment publication source Remarks
2016/12/27 Risk Assessment Phase 1-II (ecological effect)

Risk Assessment Phase 1-Ⅱ, 1-Ⅲ

publication date Status of risk assessment publication source Remarks
2023/04/01 Risk Assessment Phase 1-II (ecological effect)
2022/04/01 Risk Assessment Phase 1-II (ecological effect)
2021/04/01 Risk Assessment Phase 1-II (ecological effect)
2020/04/01 Risk Assessment Phase 1-II (ecological effect)
2019/04/01 Risk Assessment Phase 1-II (ecological effect)
2018/03/22 Risk Assessment Phase 1-II (ecological effect)


No. 101

Risk Assessment Phase 1-I

publication date Status of risk assessment publication source Remarks
2014/07/31 Risk Assessment Phase 1-II (ecological effect)





Other information

The list of high priority chemicals

CAS RN Chemical Substance Name(Reference) International Status of Collection Plan and report of sponsors Remarks
1643-20-5 dodecyldimethylamine oxide OECD HPV Program Assessed

Manufactured and/or imported quantities

Fiscal year MITI Number Registration No. Chemical Substance Name Classification Manufactured and/or imported quantities (t) Remarks
2021 2-198 169 N,N-Dimethylalkan-1-amine oxide (C=10,12,14,16,18, normal chain), (Z)-N,N-dimethyloctadec-9-en-1-amine oxide or (9Z,12Z)-N,N-dimethyloctadeca-9,12-dien-1-amine oxide Priority Assessment Chemical Substances (PACSs) 2,589
2021 2-198 Alkyl (or alkenyl, at least one of the alkyl or alkenyl groups is C8-24,others are C1-5) amine oxide General chemical substance 1 - < 1,000
2020 2-198 169 N,N-Dimethylalkan-1-amine oxide (C=10,12,14,16,18, normal chain), (Z)-N,N-dimethyloctadec-9-en-1-amine oxide or (9Z,12Z)-N,N-dimethyloctadeca-9,12-dien-1-amine oxide Priority Assessment Chemical Substances (PACSs) 3,692
2019 2-198 169 N,N-Dimethylalkan-1-amine oxide (C=10,12,14,16,18, normal chain), (Z)-N,N-dimethyloctadec-9-en-1-amine oxide or (9Z,12Z)-N,N-dimethyloctadeca-9,12-dien-1-amine oxide Priority Assessment Chemical Substances (PACSs) 3,061
2018 2-198 169 N,N-Dimethylalkan-1-amine oxide (C=10,12,14,16,18, normal chain), (Z)-N,N-dimethyloctadec-9-en-1-amine oxide or (9Z,12Z)-N,N-dimethyloctadeca-9,12-dien-1-amine oxide Priority Assessment Chemical Substances (PACSs) 4,794
2017 2-198 169 N,N-Dimethylalkan-1-amine oxide (C=10,12,14,16,18, normal chain), (Z)-N,N-dimethyloctadec-9-en-1-amine oxide or (9Z,12Z)-N,N-dimethyloctadeca-9,12-dien-1-amine oxide Priority Assessment Chemical Substances (PACSs) 3,144
2016 2-198 169 N,N-Dimethylalkan-1-amine oxide (C=10,12,14,16,18, normal chain), (Z)-N,N-dimethyloctadec-9-en-1-amine oxide or (9Z,12Z)-N,N-dimethyloctadeca-9,12-dien-1-amine oxide Priority Assessment Chemical Substances (PACSs) 2,546
2015 2-198 169 N,N-Dimethylalkan-1-amine oxide (C=10,12,14,16,18, normal chain), (Z)-N,N-dimethyloctadec-9-en-1-amine oxide or (9Z,12Z)-N,N-dimethyloctadeca-9,12-dien-1-amine oxide Priority Assessment Chemical Substances (PACSs) 1,933
2014 2-198 169 N,N-Dimethylalkan-1-amine oxide (C=10,12,14,16,18, normal chain), (Z)-N,N-dimethyloctadec-9-en-1-amine oxide or (9Z,12Z)-N,N-dimethyloctadeca-9,12-dien-1-amine oxide Priority Assessment Chemical Substances (PACSs) 1,927
2013 2-198 101 N,N-Dimethyldodecylamine N-oxide Priority Assessment Chemical Substances (PACSs) 1,982
2012 2-198 101 N,N-Dimethyldodecylamine N-oxide Priority Assessment Chemical Substances (PACSs) 1,890


Published information

publication source publication date Chemical Substance Name Published Result Judgement Remarks
Official Bulletin of Ministry of International Trade and Industry 1995/12/28 N,N-dimethyldodecylamine N-oxide Chemical substance determinated to be ready biodegradable




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