Substance Data

Chemical Substances Information

CAS RN MITI Number Chemical Substance Name Chemical Structure
18662-53-8 - Trisodium 2,2',2''-nitrilotriacetate monohydrate -


Regulatory Classification

Regulatory Classification Cabinet Order No./Registration No. Chemical Substance Name date Remarks
Priority Assessment Chemical Substances (PACSs)  152  Sodium salts of 2,2',2''-nitrilotriacetic acid  2013/12/20   
Canceled - Priority Assessment Chemical Substances  120  Trisodium 2,2',2''-nitrilotriacetate  2013/12/20  It is currently included in PACSs No. 152 (Sodium salts of 2,2',2''-nitrilotriacetic acid). 


Information of Priority Assessment Chemical Substance

Information of designation

Classification Designated date No. MITI No. Name of Priority Assessment Chemical Substance Rationale for designation Remarks
PACS  2013/12/20  152    Sodium salts of 2,2',2''-nitrilotriacetic acid 
Human health effect:x
Ecological effect:x
detailed assessment by experts for:
Canceled PACS  2013/12/20  120    Trisodium 2,2',2''-nitrilotriacetate It is currently included in PACSs No. 152 (Sodium salts of 2,2',2''-nitrilotriacetic acid).
PACS  2012/12/21  120    Trisodium 2,2',2''-nitrilotriacetate 
Human health effect:x
Ecological effect:x
detailed assessment by experts for:


No. 152

Risk Assessment Phase 1-I

publication date Status of risk assessment publication source Remarks
2023/04/01 Risk Assessment Phase 1-I (human health effect)
2022/04/01 Risk Assessment Phase 1-I (human health effect)
2021/04/01 Risk Assessment Phase 1-I (human health effect)
2020/04/01 Risk Assessment Phase 1-I (human health effect)
2019/04/01 Risk Assessment Phase 1-I (human health effect)
2018/03/22 Risk Assessment Phase 1-I (human health effect)
2016/12/27 Risk Assessment Phase 1-I (human health effect)
2015/11/26 Risk Assessment Phase 1-II (ecological effect), Risk Assessment Phase 1-I (human health effect)

Risk Assessment Phase 1-Ⅱ, 1-Ⅲ

publication date Status of risk assessment publication source Remarks
2023/04/01 Risk Assessment Phase 1-II (ecological effect)
2022/04/01 Risk Assessment Phase 1-II (ecological effect)
2021/04/01 Risk Assessment Phase 1-II (ecological effect)
2020/04/01 Risk Assessment Phase 1-II (ecological effect)
2019/04/01 Risk Assessment Phase 1-II (ecological effect)
2018/03/22 Risk Assessment Phase 1-II (ecological effect)
2016/12/27 Risk Assessment Phase 1-II (ecological effect)


No. 120

Risk Assessment Phase 1-I

publication date Status of risk assessment publication source Remarks
2014/07/31 Risk Assessment Phase 1-II (ecological effect)





Other information

Not regarded as a new chemical substance in "Implementation of the Act on the Evaluation of Chemical Substances and Regulation of Their Manufacture, etc."(operation notification ）
MITI number Chemical Substances Name Regulatory Classification Reference Article No. of CSCL Implementation Notice Remarks
2-1277 Sodium salts of 2,2',2''-nitrilotriacetic acid Priority Assessment Chemical Substances (PACSs) 152 / Existing chemical substances 
Indicated "combination" in case of more than one case of not treated as a new chemical substance.


Manufactured and/or imported quantities

Fiscal year MITI Number Registration No. Chemical Substance Name Classification Manufactured and/or imported quantities (t) Remarks
2021 2-1277 152 Sodium salts of 2,2',2''-nitrilotriacetic acid Priority Assessment Chemical Substances (PACSs) 5,493
2020 2-1277 152 Sodium salts of 2,2',2''-nitrilotriacetic acid Priority Assessment Chemical Substances (PACSs) 4,935
2019 2-1277 152 Sodium salts of 2,2',2''-nitrilotriacetic acid Priority Assessment Chemical Substances (PACSs) 11,178
2018 2-1277 152 Sodium salts of 2,2',2''-nitrilotriacetic acid Priority Assessment Chemical Substances (PACSs) 6,010
2017 2-1277 152 Sodium salts of 2,2',2''-nitrilotriacetic acid Priority Assessment Chemical Substances (PACSs) 6,264
2016 2-1277 152 Sodium salts of 2,2',2''-nitrilotriacetic acid Priority Assessment Chemical Substances (PACSs) 7,366
2015 2-1277 152 Sodium salts of 2,2',2''-nitrilotriacetic acid Priority Assessment Chemical Substances (PACSs) 7,062
2014 2-1277 152 Sodium salts of 2,2',2''-nitrilotriacetic acid Priority Assessment Chemical Substances (PACSs) 3,541
2013 2-1277 152 Sodium salts of 2,2',2''-nitrilotriacetic acid Priority Assessment Chemical Substances (PACSs) 6,402
2012 2-1277 120 Trisodium 2,2',2''-nitrilotriacetate Priority Assessment Chemical Substances (PACSs) 4,735


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