Substance Data

Chemical Substances Information

CAS RN MITI Number Chemical Substance Name Chemical Structure
584-84-9 3-2214 Toluene 2,4-diisocyanate


Regulatory Classification

Regulatory Classification Cabinet Order No./Registration No. Chemical Substance Name date Remarks
Canceled - Priority Assessment Chemical Substances  129  1,3-Diisocyanato(methyl)benzene  2025/03/31   
Existing chemical substances  -  Diisocyanatotoluene     


Screening Info

Publication year Human health effect Ecological effect Detailed assessment by experts Remarks
Exposure Class Hazard Class Priority Exposure Class Hazard Class Priority
2023 - - - 5 3 Low Assessment has been conducted by the serial number of Priority Assessment Chemical Substances (PACSs).
2022 - - - 5 3 Low Assessment has been conducted by the serial number of Priority Assessment Chemical Substances (PACSs).
2021 - - - 5 3 Low Assessment has been conducted by the serial number of Priority Assessment Chemical Substances (PACSs).
2020 5 3 Low Assessment has been conducted by the serial number of Priority Assessment Chemical Substances (PACSs).
2019 5 3 Low Assessment has been conducted by the serial number of Priority Assessment Chemical Substances (PACSs).
2018 5 3 Low Assessment has been conducted by the serial number of Priority Assessment Chemical Substances (PACSs).
2017 4 3 Medium Assessment has been conducted by the serial number of Priority Assessment Chemical Substances (PACSs).
2016 5 3 Low Assessment has been conducted by the serial number of Priority Assessment Chemical Substances (PACSs).
2013 5 - - Out of classification - - Assessment has been conducted by the CAS RN.
2012 5 2 Medium Out of classification - - Assessment has been conducted by the CAS RN.


Remarks


Information of Priority Assessment Chemical Substance

Information of designation

Classification Designated date No. MITI No. Name of Priority Assessment Chemical Substance Rationale for designation Remarks
Canceled PACS  2025/03/31  129  3-2214  1,3-Diisocyanato(methyl)benzene
PACS  2012/12/21  129  3-2214  1,3-Diisocyanato(methyl)benzene 
Human health effect:x
Ecological effect:
detailed assessment by experts for:


No. 129

Risk Assessment Phase 1-I

publication date Status of risk assessment publication source Remarks
2015/11/26 Risk Assessment Phase 1-II (human health effect)
2014/07/31 Risk Assessment Phase 1-I

Risk Assessment Phase 1-Ⅱ, 1-Ⅲ

publication date Status of risk assessment publication source Remarks
2024/04/01 Risk Assessment Phase 1-II (human health effect)
2023/04/01 Risk Assessment Phase 1-II (human health effect)
2022/04/01 Risk Assessment Phase 1-II (human health effect)
2021/04/01 Risk Assessment Phase 1-II (human health effect)
2020/04/01 Risk Assessment Phase 1-II (human health effect)
2019/04/01 Risk Assessment Phase 1-II (human health effect)
2018/03/22 Risk Assessment Phase 1-II (human health effect)
2016/12/27 Risk Assessment Phase 1-II (human health effect)






Other information

The list of high priority chemicals

CAS RN Chemical Substance Name(Reference) International Status of Collection Plan and report of sponsors Remarks
584-84-9 4-methyl-m-phenylene diisocyanate OECD HPV Program Plans Assessment

Manufactured and/or imported quantities

Fiscal year MITI Number Registration No. Chemical Substance Name Classification Manufactured and/or imported quantities (t) Remarks
2022 3-2214 129 1,3-Diisocyanato(methyl)benzene Priority Assessment Chemical Substances (PACSs) 87,294
2021 3-2214 129 1,3-Diisocyanato(methyl)benzene Priority Assessment Chemical Substances (PACSs) 108,861
2020 3-2214 129 1,3-Diisocyanato(methyl)benzene Priority Assessment Chemical Substances (PACSs) 105,372
2019 3-2214 129 1,3-Diisocyanato(methyl)benzene Priority Assessment Chemical Substances (PACSs) 105,771
2018 3-2214 129 1,3-Diisocyanato(methyl)benzene Priority Assessment Chemical Substances (PACSs) 111,406
2017 3-2214 129 1,3-Diisocyanato(methyl)benzene Priority Assessment Chemical Substances (PACSs) 118,949
2016 3-2214 129 1,3-Diisocyanato(methyl)benzene Priority Assessment Chemical Substances (PACSs) 99,503
2015 3-2214 129 1,3-Diisocyanato(methyl)benzene Priority Assessment Chemical Substances (PACSs) 192,836
2014 3-2214 129 1,3-Diisocyanato(methyl)benzene Priority Assessment Chemical Substances (PACSs) 226,308
2013 3-2214 129 1,3-Diisocyanato(methyl)benzene Priority Assessment Chemical Substances (PACSs) 225,653
2012 3-2214 129 1,3-Diisocyanato(methyl)benzene Priority Assessment Chemical Substances (PACSs) 219,059


Published information

publication source publication date Chemical Substance Name Published Result Judgement Remarks
Official Bulletin of Economy, Trade and Industry 2003/10/14 4-methyl-1,3-phenylene diisocyanate Chemical substance determinated to be persistent but not highly bioaccumulative




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