Substance Data

Chemical Substances Information

CAS RN MITI Number Chemical Substance Name Chemical Structure
64359-81-5 5-6165 4,5-dichloro-2-octyl-2H-isothiazol-3-one


Regulatory Classification

Regulatory Classification Cabinet Order No./Registration No. Chemical Substance Name date Remarks
Priority Assessment Chemical Substances (PACSs)  221  4,5-Dichloro-2-octylisothiazol-3(2H)-one  2017/04/03   
Designated (before amendment)  61  4,5-Dichloro-2-n-octylisothiazol-3-one  1990/03/26   


Screening Info

Publication year Human health effect Ecological effect Detailed assessment by experts Remarks
Exposure Class Hazard Class Priority Exposure Class Hazard Class Priority
2016 5 - - 5 1 Medium Result of detailed assessment by experts on ecological effect, it has been selected as Priority Assessment Chemical Substances (PACSs). Assessment has been conducted by the serial number of Type II Monitoring Chemical Substance (before amendment).
2015 5 - - 5 - - Assessment has been conducted by the serial number of Type II Monitoring Chemical Substance (before amendment).
2014 5 - - 5 - - Assessment has been conducted by the serial number of Type II Monitoring Chemical Substance (before amendment).
2013 5 - - 5 - - Assessment has been conducted by the serial number of Type II Monitoring Chemical Substance (before amendment).
2012 5 - - 5 - - Assessment has been conducted by the serial number of Type II Monitoring Chemical Substance (before amendment).
2010 4 2 Medium - - - Assessment has been conducted by the serial number of Type II Monitoring Chemical Substance (before amendment).


Remarks


Information of Priority Assessment Chemical Substance

Information of designation

Classification Designated date No. MITI No. Name of Priority Assessment Chemical Substance Rationale for designation Remarks
PACS  2017/04/03  221  5-6165  4,5-Dichloro-2-octylisothiazol-3(2H)-one 
Human health effect:
Ecological effect:x
detailed assessment by experts for:Ecological effect


No. 221

Risk Assessment Phase 1-I

publication date Status of risk assessment publication source Remarks
2023/04/01 Risk Assessment Phase 1-I (ecological effect)
2022/04/01 Risk Assessment Phase 1-I (ecological effect)
2021/04/01 Risk Assessment Phase 1-I (ecological effect)
2020/04/01 Risk Assessment Phase 1-I (ecological effect)
2019/04/01 Risk Assessment Phase 1-I (ecological effect)

Risk Assessment Phase 1-Ⅱ, 1-Ⅲ

publication date Status of risk assessment publication source Remarks
2024/04/01 Risk Assessment Phase 1-II (ecological effect)






Published information

publication source publication date Chemical Substance Name Published Result Judgement Remarks
METI website (Only available in Japanese) 2019/09/06 4,5-Dichloro-2-n-octylisothiazol-3-one Not readily biodegradable / Not highly bioaccumulative
METI website (Only available in Japanese) 2019/09/06 4,5-Dichloro-2-n-octylisothiazol-3-one Test method : Bioaccumulation in Fish, Test result : BCF = 1189 The test result is the maximum value of BCF.


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