Substance Data

Chemical Substances Information

CAS RN MITI Number Chemical Substance Name Chemical Structure
66558-66-5 - Compound of 2,2'-{ethane-1,2-diylbis[(methoxycarbonyl)imino]}diacetic acid and 2,2',2''-nitrilotriethanol


Regulatory Classification

Regulatory Classification Cabinet Order No./Registration No. Chemical Substance Name date Remarks
Priority Assessment Chemical Substances (PACSs)  108  Triethanolamine  2012/12/21   
Priority Assessment Chemical Substances (PACSs)  36  Ethylenediaminetetraacetic acid  2011/04/01   


Screening Info

Publication year Human health effect Ecological effect Detailed assessment by experts Remarks
Exposure Class Hazard Class Priority Exposure Class Hazard Class Priority
2022 - - - 2 4 Medium Assessment has been conducted by the serial number 108 of Priority Assessment Chemical Substances (PACSs).
2021 - - - 2 4 Medium Assessment has been conducted by the serial number 108 of Priority Assessment Chemical Substances (PACSs).
2020 2 4 Medium Assessment has been conducted by the serial number 108 of Priority Assessment Chemical Substances (PACSs).
2019 2 4 Medium Assessment has been conducted by the serial number 108 of Priority Assessment Chemical Substances (PACSs).
2018 2 4 Medium Assessment has been conducted by the serial number 108 of Priority Assessment Chemical Substances (PACSs).
2017 2 4 Medium Assessment has been conducted by the serial number 108 of Priority Assessment Chemical Substances (PACSs).
2016 2 4 Medium Assessment has been conducted by the serial number 108 of Priority Assessment Chemical Substances (PACSs).
2015 2 4 Medium Assessment has been conducted by the serial number 108 of Priority Assessment Chemical Substances (PACSs).
2015 2 2 High Assessment has been conducted by the serial number 36 of Priority Assessment Chemical Substances (PACSs).
2014 2 4 Medium Assessment has been conducted by the serial number 108 of Priority Assessment Chemical Substances (PACSs).


Remarks


Information of Priority Assessment Chemical Substance

Information of designation

Classification Designated date No. MITI No. Name of Priority Assessment Chemical Substance Rationale for designation Remarks
PACS  2012/12/21  108    Triethanolamine 
Human health effect:x
Ecological effect:
detailed assessment by experts for:
PACS  2011/04/01  36    Ethylenediaminetetraacetic acid 
Human health effect:x
Ecological effect:x (2015/10/23)
detailed assessment by experts for:


No. 108

Risk Assessment Phase 1-I

publication date Status of risk assessment publication source Remarks
2023/04/01 Risk Assessment Phase 1-I (human health effect)
2022/04/01 Risk Assessment Phase 1-I (human health effect)
2021/04/01 Risk Assessment Phase 1-I (human health effect)
2020/04/01 Risk Assessment Phase 1-I (human health effect)
2019/04/01 Risk Assessment Phase 1-I (human health effect)
2018/03/22 Risk Assessment Phase 1-I (human health effect)
2016/12/27 Risk Assessment Phase 1-I (human health effect)
2015/11/26 Risk Assessment Phase 1-I
2014/07/31 Risk Assessment Phase 1-I

No. 36

Risk Assessment Phase 1-I

publication date Status of risk assessment publication source Remarks
2023/04/01 Risk Assessment Phase 1-I (human health effect)
2022/04/01 Risk Assessment Phase 1-I (human health effect)
2021/04/01 Risk Assessment Phase 1-I (human health effect)
2020/04/01 Risk Assessment Phase 1-I (human health effect)
2019/04/01 Risk Assessment Phase 1-I (human health effect)
2018/03/22 Risk Assessment Phase 1-I (human health effect)
2016/12/27 Risk Assessment Phase 1-I (human health effect), Risk Assessment Phase 1-II (ecological effect)
2015/11/26 Risk Assessment Phase 1-I
2014/07/31 Risk Assessment Phase 1-I

Risk Assessment Phase 1-Ⅱ, 1-Ⅲ

publication date Status of risk assessment publication source Remarks
2023/04/01 Risk Assessment Phase 1-II (ecological effect)
2022/04/01 Risk Assessment Phase 1-II (ecological effect)
2021/04/01 Risk Assessment Phase 1-II (ecological effect)
2020/04/01 Risk Assessment Phase 1-II (ecological effect)
2019/04/01 Risk Assessment Phase 1-II (ecological effect)
2018/03/22 Risk Assessment Phase 1-II (ecological effect)






Other information

Not regarded as a new chemical substance in "Implementation of the Act on the Evaluation of Chemical Substances and Regulation of Their Manufacture, etc."(operation notification ）
MITI number Chemical Substances Name Regulatory Classification Reference Article No. of CSCL Implementation Notice Remarks
2-1263 Ethylenediaminetetraacetic acid Priority Assessment Chemical Substances (PACSs) 36 / Existing chemical substances / Type II Monitoring Chemical Substances (before amendment) Combination 1
2-308 Triethanolamine Priority Assessment Chemical Substances (PACSs) 108 / Existing chemical substances Combination 1
2-1263 Ethylenediaminetetraacetic acid Priority Assessment Chemical Substances (PACSs) 36 / Existing chemical substances / Type II Monitoring Chemical Substances (before amendment) Combination 2
2-353 Triethanolamine Priority Assessment Chemical Substances (PACSs) 108 / Existing chemical substances Combination 2 
Indicated "combination" in case of more than one case of not treated as a new chemical substance.


Manufactured and/or imported quantities

Fiscal year MITI Number Registration No. Chemical Substance Name Classification Manufactured and/or imported quantities (t) Remarks
2021 2-1263 36 Ethylenediaminetetraacetic acid Priority Assessment Chemical Substances (PACSs) 3,368
2021 2-308 108 Triethanolamine Priority Assessment Chemical Substances (PACSs) 16,247 MITI number: 2-308, 2-353
2020 2-1263 36 Ethylenediaminetetraacetic acid Priority Assessment Chemical Substances (PACSs) 2,479
2020 2-308 108 Triethanolamine Priority Assessment Chemical Substances (PACSs) 14,482 MITI number: 2-308, 2-353
2019 2-1263 36 Ethylenediaminetetraacetic acid Priority Assessment Chemical Substances (PACSs) 2,780
2019 2-308 108 Triethanolamine Priority Assessment Chemical Substances (PACSs) 15,524 MITI number: 2-308, 2-353
2018 2-1263 36 Ethylenediaminetetraacetic acid Priority Assessment Chemical Substances (PACSs) 2,515
2018 2-308 108 Triethanolamine Priority Assessment Chemical Substances (PACSs) 17,079 MITI number: 2-308,2-353
2017 2-1263 36 Ethylenediaminetetraacetic acid Priority Assessment Chemical Substances (PACSs) 2,857
2017 2-308 108 Triethanolamine Priority Assessment Chemical Substances (PACSs) 15,121
2016 2-1263 36 Ethylenediaminetetraacetic acid Priority Assessment Chemical Substances (PACSs) 2,463
2016 2-308 108 Triethanolamine Priority Assessment Chemical Substances (PACSs) 15,485
2015 2-1263 36 Ethylenediaminetetraacetic acid Priority Assessment Chemical Substances (PACSs) 2,863
2015 2-308 108 Triethanolamine Priority Assessment Chemical Substances (PACSs) 15,733
2014 2-1263 36 Ethylenediaminetetraacetic acid Priority Assessment Chemical Substances (PACSs) 2,390
2014 2-308 108 Triethanolamine Priority Assessment Chemical Substances (PACSs) 14,883
2013 2-1263 36 Ethylenediaminetetraacetic acid Priority Assessment Chemical Substances (PACSs) 2,129
2013 2-308 108 Triethanolamine Priority Assessment Chemical Substances (PACSs) 14,518
2012 2-1263 36 Ethylenediaminetetraacetic acid Priority Assessment Chemical Substances (PACSs) 1,872
2012 2-308 108 Triethanolamine Priority Assessment Chemical Substances (PACSs) 13,182


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