| ID |
NRULE_0002 |
| 遺伝子ID |
NHAB |
| 作成日 |
2012/06/29 |
| タンパク質名 |
Protein name
- Full
- Nitrile hydratase subunit beta
- Short
- NHase
- EC
- EC 4.2.1.84
|
| 遺伝子名 |
nthB |
| 遺伝子条件 |
PFAM; PF02211; hit=1ANDTIGRFAMs; TIGR03888; hit=1 |
| 参照 |
Gene Ontology
- GO
- GO:0046914, F:transition metal ion binding, IEA:InterPro
- GO:0006807, P:nitrogen compound metabolic process, IEA:InterPro
Family and domain databases
- InterPro
- IPR024690, CN_hydtase_beta_dom
- IPR008990, Elect_transpt_acc-like_dom
- IPR003168, Nitrile_hydratase_bsu
- Pfam
- PF02211, NHase_beta, 1
- PIRSF
- PIRSF001427, NHase_beta, 1
- TIGRFAMs
- TIGR03888, Nitrile_beta, 1
|
| 配列の特徴 |
該当データなし |
| 注釈 |
- Function
- NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. Industrial production of acrylamide is now being developed using some of the enzymes of this class
- Catalytic activity
- An aliphatic amide = a nitrile + H(2)O
- Subunit structure
- Heterodimer of an alpha and a beta chain
- Sequence similarities
- Belongs to the nitrile hydratase subunit beta family
|
| 参考文献 |
- P13449 Rhodococcus erythropolis (Arthrobacter picolinophilus).
- 2659343
- Primary structure of nitrile hydratase deduced from the nucleotide sequence of a Rhodococcus species and its expression in Escherichia coli. (Eur J Biochem. 1989)
- 10101282
- Functional expression of nitrile hydratase in Escherichia coli: requirement of a nitrile hydratase activator and post-translational modification of a ligand cysteine. (J Biochem. 1999)
- P21220 Rhodococcus rhodochrous.
- 8633053
- Characterization of the gene cluster of high-molecular-mass nitrile hydratase (H-NHase) induced by its reaction product in Rhodococcus rhodochrous J1. (Proc Natl Acad Sci U S A. 1996)
- P29379 Rhodococcus rhodochrous.
- 1840499
- Cloning, nucleotide sequence and expression in Escherichia coli of two cobalt-containing nitrile hydratase genes from Rhodococcus rhodochrous J1. (Biochim Biophys Acta. 1991)
|
