遺伝子 : Rubredoxin reductase (RUBB)

遺伝子情報

ID	NRULE_0040
遺伝子ID	RUBB
作成日	2012/09/07
タンパク質名	Protein name Full Rubredoxin reductase EC EC 1.18.1.1
遺伝子名	rubB
遺伝子条件	BLASTP; Q0VTB0; hit=1; score=639; pid=38 OR BLASTP; Q93DN0; hit=1; score=770; pid=41 OR BLASTP; P17052; hit=1; score=750; pid=40
参照	Gene Ontology GO GO:0050660, F:flavin adenine dinucleotide binding, IEA:InterPro GO:0015044, F:rubredoxin-NAD+ reductase activity, IEA:EC GO:0043448, P:alkane catabolic process, IMP:UniProtKB Phylogenomic databases KO K05297, - Enzyme and pathway databases UniPathway UPA00191, - Family and domain databases InterPro IPR013027, FAD_pyr_nucl-diS_OxRdtase IPR023753, Pyr_nucl-diS_OxRdtase_FAD/NAD IPR001327, Pyr_OxRdtase_NAD-bd_dom Pfam PF00070, Pyr_redox, 1 PF07992, Pyr_redox_2, 1 PRINTS PR00368, FADPNR
配列の特徴	P17052 Pseudomonas oleovorans. BINDING 41 FAD or NAD. BINDING 79 FAD or NAD; viaamide nitrogen and carbonyl oxygen. BINDING 156 FAD or NAD.
注釈	Function Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1-monooxygenase Catalytic activity 2 reduced rubredoxin + NAD(+) + H(+)= 2 oxidized rubredoxin + NADH Cofactor FAD Pathway Hydrocarbon metabolism; alkane degradation Subunit structure Homodimer Sequence similarities Belongs to the FAD-dependent oxidoreductase family
参考文献	P17052 Pseudomonas oleovorans. 2319593 Rubredoxin reductase of Pseudomonas oleovorans. Structural relationship to other flavoprotein oxidoreductases based on one NAD and two FAD fingerprints. (J Mol Biol. 1990) Q0VTB0 Alcanivorax borkumensis (strain ATCC 700651 / DSM 11573 / NCIMB 13689 SK2). 21714118 Rubredoxin reductase from Alcanivorax borkumensis: expression and characterization. (Biotechnol Prog. 2011) Q93DN0 Rhodococcus sp. (strain Q15). 12450813 Gene cloning and characterization of multiple alkane hydroxylase systems in Rhodococcus strains Q15 and NRRL B-16531. (Appl Environ Microbiol. 2002)

関与する機能

機能名
n-alkane hydroxylation

該当CDS

学名	NBRC番号	CDS	タンパク質名
Acinetobacter radioresistens	102413	ACRAD_02_01990	rubredoxin reductase
Acinetobacter sp.	100985	ACT4_013_00270	rubredoxin-NAD(+) reductase
Congregibacter litoralis	104960	KT71_05015	NAD(P)H-nitrite reductase
Halomonas elongata	15536	HELO_4414	FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Magnetospirillum magnetotacticum	15272	Magn03010384	COG0446: Uncharacterized NAD(FAD)-dependent dehydrogenases
Nitrosomonas europaea	14298	NE1420	probable rubredoxin reductase
Pseudomonas putida	100650	PP_5314	rubredoxin reductase
		PP_5371	rubredoxin/rubredoxin reductase
Pseudomonas stutzeri	14165	PSTAB_0469	rubredoxin reductase
Rhodococcus erythropolis	100887	RER_07490	rubredoxin reductase
Rhodococcus opacus	108011	ROP_22600	rubredoxin reductase
		ROP_pROB01-04380	rubredoxin reductase
Tsukamurella paurometabola	16120	Tpau_2747	FAD-dependent pyridine nucleotide-disulfide oxidoreductase