遺伝子 : Aromatic ring hydroxylase (PHEA2)

遺伝子情報

ID	NRULE_0084
遺伝子ID	PHEA2
作成日	2012/11/21
タンパク質名	Protein name Full Aromatic ring hydroxylase EC EC 1.14.13.- Synonym Full Aromatic hydrocarbon monooxygenase
遺伝子名	該当データなし
遺伝子条件	BLASTP; P31020; hit=1; score=820; pid=35 OR BLASTP; Q6SSJ6; hit=1; score=720; pid=30 OR HAMAP; MF_01652; hit=1
参照	Family and domain databases InterPro IPR002938, mOase_FAD-bd IPR003042, Rng_hydrolase-like Pfam PF01494, FAD_binding_3, 1 PRINTS PR00420, RNGMNOXGNASE
配列の特徴	該当データなし
注釈	Function Hydroxylation of phenol derivatives to catechol derivatives Cofactor FAD Pathway Aromatic compound metabolism Sequence similarities Belongs to the PheA/TfdB FAD monooxygenase family
参考文献	P31020 Pseudomonas sp. (strain EST1001). 1650730 Sequence of the gene (pheA) encoding phenol monooxygenase from Pseudomonas sp. EST1001: expression in Escherichia coli and Pseudomonas putida. (Gene. 1991) Q6SSJ6 Comamonas testosteroni (Pseudomonas testosteroni). 17045293 Crystal structure of 3-hydroxybenzoate hydroxylase from Comamonas testosteroni has a large tunnel for substrate and oxygen access to the active site. (J Mol Biol. 2006) P77397 Escherichia coli (strain K12). 9098055 Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia coli K-12. (J Bacteriol. 1997) P27138 Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134)). 2185214 Organization and sequence analysis of the 2,4-dichlorophenol hydroxylase and dichlorocatechol oxidative operons of plasmid pJP4. (J Bacteriol. 1990)

関与する機能

機能名
Phenol degradation

該当CDS

学名	NBRC番号	CDS	タンパク質名
Amycolatopsis mediterranei	13415	RAM_30725	FAD-dependent oxidoreductase
Arthrobacter globiformis	12137	ARGLB_027_02000	putative phenol 2-monooxygenase
		ARGLB_110_00190	putative phenol 2-monooxygenase
		ARGLB_110_00230	putative phenol 2-monooxygenase
Bradyrhizobium diazoefficiens	14792	blr4222	putative phenol 2-monooxygenase (EC 1.14.13.7)
Brevibacterium linens	12170	BlinB_010200012311	phenol 2-monooxygenase
Cellulomonas fimi	15513	Celf_2070	Phenol hydroxylase domain protein dimerization
Corynebacterium ammoniagenes	12612	HMPREF0281_00614	FAD binding domain protein
		HMPREF0281_01056	FAD binding domain protein
Corynebacterium efficiens	100395	CE2219	putative phenol 2-monooxygenase
Corynebacterium glutamicum	12168	Cgl2681	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Corynebacterium glutamicum	12153	KIQ_12310	phenol 2-monooxygenase
Corynebacterium striatum	15291	HMPREF0308_2494	FAD binding domain protein
Escherichia coli	3972	EcolC_3278	monooxygenase FAD-binding
Escherichia coli	13500	WFL_02090	3-(3-hydroxyphenyl)propionate hydroxylase
Escherichia coli	12713	Y75_0337	3-(3-hydroxyphenyl)propionate hydroxylase
Gordonia aichiensis	108223	GOACH_01_01900	putative phenol monooxygenase
		GOACH_22_00900	putative phenol monooxygenase
Gordonia amarae	15530	GOAMR_25_00110	putative phenol monooxygenase
Gordonia otitidis	100426	GOOTI_109_00280	putative monooxygenase
Gordonia polyisoprenivorans	16320	GOPIP_092_00690	putative phenol 2-monooxygenase
		GOPIP_093_00410	putative phenol monooxygenase
Gordonia rhizosphera	16068	GORHZ_126_00250	putative phenol 2-monooxygenase
Gordonia sihwensis	108236	GSI01S_15_00850	putative monooxygenase
Gordonia sputi	100414	GOSPT_003_00210	putative monooxygenase
Hylemonella gracilis	14920	HGR_05469	phenol 2-monooxygenase
Kocuria rhizophila	103217	KRH_22060	putative phenol 2-monooxygenase
Labrenzia aggregata	16684	SIAM614_03563	phenol 2-monooxygenase
Micrococcus luteus	3333	Mlut_20120	2-polyprenyl-6-methoxyphenol hydroxylase-like oxidoreductase
Nakamurella multipartita	105858	Namu_0227	monooxygenase FAD-binding
Rubrobacter xylanophilus	100952	Rxyl_0473	Phenol hydroxylase-like dimerisation
Shimwellia blattae	105725	EB105725_09_00100	3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase
Sphingobium japonicum	101211	SJA_C1-21170	dichlorophenol hydroxylase
Sphingomonas wittichii	105917	Swit_2298	monooxygenase, FAD-binding
		Swit_3045	monooxygenase, FAD-binding
Streptomyces mobaraensis	13819	H340_25572	FAD-binding monooxygenase
Zimmermannella faecalis	15706	G328_05435	hypothetical protein