BLAST table : Amph_00160

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
Q93NW7_9ACTO
(Q93NW7)
[query] 1 - 3190 (3190)
[subject] 1 - 3190 (3190)
0.0 6271   100% AmphB amphB Streptomyces nodosus
2
Q9L4W4_9ACTO
(Q9L4W4)
Jump to Nysta_00140
[query] 1 - 3190 (3190)
[subject] 1 - 3192 (3192)
0.0 4622   78% NysB nysB Streptomyces noursei
3
D2CKM3_PSEAH
(D2CKM3)
[query] 3 - 3190 (3190)
[subject] 2 - 3175 (3175)
0.0 4013   70% CppB cppB Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
4
Q93NX9_9ACTO
(Q93NX9)
Jump to Amph_00040
[query] 37 - 3112 (3190)
[subject] 3315 - 6378 (9510)
(7 hsp)
0.0 3261   61% AmphI amphI Streptomyces nodosus
5
Q9L4X3_9ACTO
(Q9L4X3)
Jump to Nysta_00050
[query] 37 - 3113 (3190)
[subject] 3356 - 6428 (9477)
(8 hsp)
0.0 3114   60% NysI nysI Streptomyces noursei
6
D2CKL5_PSEAH
(D2CKL5)
[query] 37 - 3113 (3190)
[subject] 3336 - 6410 (9499)
(7 hsp)
0.0 3101   58% CppI cppI Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
7
D7BRE1_STRBB
(D7BRE1)
[query] 38 - 3112 (3190)
[subject] 451 - 3511 (5139)
(4 hsp)
0.0 3083   56% Modular polyketide synthase SBI_01983 Streptomyces bingchenggensis (strain BCW-1)
8
F1CLA9_9ACTO
(F1CLA9)
[query] 38 - 3114 (3190)
[subject] 3323 - 6387 (9498)
(7 hsp)
0.0 3033   57% ScnS2 scnS2 Streptomyces chattanoogensis
9
Q9EWA1_9ACTO
(Q9EWA1)
Jump to Pimar_00070
[query] 38 - 3123 (3190)
[subject] 3331 - 6402 (9507)
(7 hsp)
0.0 3019   57% PimS2 protein pimS2 Streptomyces natalensis
10
D9WQ82_9ACTO
(D9WQ82)
[query] 7 - 3102 (3190)
[subject] 3 - 3109 (3199)
0.0 2984   56% Erythronolide synthase, modules 1 and 2 SSOG_05756 Streptomyces himastatinicus ATCC 53653
11
Q6W5P6_9ACTO
(Q6W5P6)
Jump to FR008_00200
[query] 38 - 3111 (3190)
[subject] 3342 - 6407 (9550)
(7 hsp)
0.0 2972   56% FscD fscD Streptomyces sp. FR-008
12
B4VB12_9ACTO
(B4VB12)
[query] 8 - 3102 (3190)
[subject] 3 - 3119 (3203)
0.0 2896   54% Polyketide synthase type I SSAG_04922 Streptomyces sp. Mg1
13
Q52V51_9ACTO
(Q52V51)
[query] 8 - 3102 (3190)
[subject] 3 - 3143 (3227)
0.0 2892   54% Polyketide synthase type I Streptomyces aizunensis
14
E0KBI2_STRVO
(E0KBI2)
[query] 37 - 3180 (3190)
[subject] 1758 - 4925 (4930)
(4 hsp)
0.0 2883   52% Mycocerosate synthase., 6-deoxyerythronolide-B synthase StrviDRAFT_0197 Streptomyces violaceusniger Tu 4113 2.3.1.111

2.3.1.94
15
C9YYI3_STRSW
(C9YYI3)
[query] 9 - 3126 (3190)
[subject] 6 - 3203 (5001)
(4 hsp)
0.0 2867   54% Putative type I polyketide synthase SCAB_83921 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
16
Q3S869_9ACTO
(Q3S869)
Jump to Conca_00080
[query] 9 - 3126 (3190)
[subject] 6 - 3202 (5006)
(4 hsp)
0.0 2850   54% Modular polyketide synthase Streptomyces neyagawaensis
17
E0KBI6_STRVO
(E0KBI6)
[query] 8 - 3102 (3190)
[subject] 2 - 3132 (4996)
(4 hsp)
0.0 2832   52% Acyl transferase StrviDRAFT_0201 Streptomyces violaceusniger Tu 4113
18
C9YYI1_STRSW
(C9YYI1)
[query] 9 - 3111 (3190)
[subject] 4 - 3111 (4970)
(4 hsp)
0.0 2819   55% Putative type I polyketide synthase SCAB_83901 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
19
F1ADL9_9ACTO
(F1ADL9)
[query] 6 - 3114 (3190)
[subject] 1 - 3177 (5145)
(6 hsp)
0.0 2817   53% BafAII Streptomyces lohii
20
Q3S864_9ACTO
(Q3S864)
Jump to Conca_00060
[query] 9 - 3111 (3190)
[subject] 4 - 3111 (4970)
(6 hsp)
0.0 2810   55% Nodular polyketide synthase Streptomyces neyagawaensis
21
E0D202_9ACTO
(E0D202)
Jump to FD891_00010
[query] 38 - 3126 (3190)
[subject] 1037 - 4089 (7480)
(9 hsp)
0.0 2777   53% Polyketide synthase gfsA Streptomyces graminofaciens
22
E0KBI5_STRVO
(E0KBI5)
[query] 8 - 3102 (3190)
[subject] 3 - 3117 (3205)
(3 hsp)
0.0 2753   53% Acyl transferase StrviDRAFT_0200 Streptomyces violaceusniger Tu 4113
23
E4NJF2_KITSK
(E4NJF2)
[query] 6 - 3108 (3190)
[subject] 1 - 3127 (5004)
(4 hsp)
0.0 2741   54% Modular polyketide synthase BFAS2 bfmA2
KSE_73450
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
24
Q93HJ2_STRAW
(Q93HJ2)
Jump to Oligo_00110
[query] 6 - 3120 (3190)
[subject] 2 - 3086 (4685)
(2 hsp)
0.0 2718   53% Modular polyketide synthase olmA6
SAV2896
SAV_2896
Streptomyces avermitilis
25
B1W487_STRGG
(B1W487)
[query] 7 - 3114 (3190)
[subject] 3 - 3105 (3188)
(2 hsp)
0.0 2712   52% Putative type-I PKS pks1-3
SGR_6075
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
26
D5ZU01_9ACTO
(D5ZU01)
[query] 2 - 3102 (3190)
[subject] 25 - 3005 (4790)
(6 hsp)
0.0 2679   53% Nodular polyketide synthase SSFG_00090 Streptomyces ghanaensis ATCC 14672
27
Q93H83_STRAW
(Q93H83)
[query] 7 - 3120 (3190)
[subject] 3 - 3067 (3352)
0.0 2640   51% Modular polyketide synthase pteA5
SAV415
SAV_415
Streptomyces avermitilis
28
Q0ILD1_9ACTO
(Q0ILD1)
[query] 11 - 3126 (3190)
[subject] 3 - 3070 (4635)
(2 hsp)
0.0 2635   51% NlmA6 nlmA6 Streptomyces nanchangensis
29
Q68BG5_STRHA
(Q68BG5)
Jump to Halsto_00010
[query] 35 - 3182 (3190)
[subject] 1016 - 4188 (4194)
(5 hsp)
0.0 2634   50% Type I polyketide synthase hlsA Streptomyces halstedii
30
E8S0C1_MICSL
(E8S0C1)
[query] 36 - 3102 (3190)
[subject] 1538 - 4621 (4706)
(3 hsp)
0.0 2622   52% 6-deoxyerythronolide-B synthase., (Acyl-carrier-protein) S-acetyltransferase ML5_5894 Micromonospora sp. (strain L5) 2.3.1.38

2.3.1.94
31
D7C2C3_STRBB
(D7C2C3)
[query] 38 - 2995 (3190)
[subject] 1870 - 4852 (4868)
(5 hsp)
0.0 2608   53% Modular polyketide synthase pks3-4
SBI_00656
Streptomyces bingchenggensis (strain BCW-1)
32
D9T6W8_MICAI
(D9T6W8)
[query] 36 - 3102 (3190)
[subject] 1542 - 4625 (4710)
(3 hsp)
0.0 2597   52% Beta-ketoacyl synthase Micau_2468 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
33
Q9KIV4_STRAT
(Q9KIV4)
[query] 37 - 3190 (3190)
[subject] 1060 - 4149 (4150)
(5 hsp)
0.0 2578   51% 8,8a-deoxyoleandolide synthase 1 oleAI Streptomyces antibioticus
34
E0KRC6_STRVO
(E0KRC6)
[query] 37 - 3102 (3190)
[subject] 2929 - 5897 (11118)
(12 hsp)
0.0 2565   51% Beta-ketoacyl synthase StrviDRAFT_5203 Streptomyces violaceusniger Tu 4113
35
E0KBI3_STRVO
(E0KBI3)
[query] 37 - 3163 (3190)
[subject] 1589 - 4707 (4750)
(2 hsp)
0.0 2556   49% 6-methylsalicylic acid synthase., 6-deoxyerythronolide-B synthase StrviDRAFT_0198 Streptomyces violaceusniger Tu 4113 2.3.1.165

2.3.1.94
36
E0KFI9_STRVO
(E0KFI9)
[query] 29 - 3108 (3190)
[subject] 5024 - 8156 (8238)
(6 hsp)
0.0 2554   50% Beta-ketoacyl synthase StrviDRAFT_1372 Streptomyces violaceusniger Tu 4113
37
E0KBI4_STRVO
(E0KBI4)
[query] 8 - 3109 (3190)
[subject] 3 - 3118 (8275)
(6 hsp)
0.0 2550   49% Beta-ketoacyl synthase StrviDRAFT_0199 Streptomyces violaceusniger Tu 4113
38
D3Y1I3_9ACTO
(D3Y1I3)
[query] 39 - 3102 (3190)
[subject] 1024 - 3996 (5828)
(7 hsp)
0.0 2541   50% TamAI Streptomyces sp. 307-9
39
Q9ALM4_9PSEU
(Q9ALM4)
Jump to Spino_00190
[query] 7 - 3109 (3190)
[subject] 2 - 3093 (3170)
(2 hsp)
0.0 2541   51% Polyketide synthase extender modules 3-4 spnC Saccharopolyspora spinosa
40
Q1WEK7_9ACTO
(Q1WEK7)
[query] 37 - 3122 (3190)
[subject] 2952 - 5943 (7968)
(6 hsp)
0.0 2540   51% Polyketide synthase merC Streptomyces sp. NRRL 30748
41
F1DI31_9ACTO
(F1DI31)
[query] 38 - 3102 (3190)
[subject] 1023 - 3997 (5829)
(7 hsp)
0.0 2534   50% TrdAI Streptomyces sp. SCSIO1666
42
Q93H84_STRAW
(Q93H84)
[query] 22 - 3109 (3190)
[subject] 2 - 3029 (6145)
(2 hsp)
0.0 2533   50% Modular polyketide synthase pteA4
SAV416
SAV_416
Streptomyces avermitilis
43
D1GLV9_9ACTO
(D1GLV9)
Jump to Strply_00310
[query] 32 - 3117 (3190)
[subject] 1062 - 4179 (6171)
(7 hsp)
0.0 2500   49% Polyketide synthase type I slgA1 Streptomyces lydicus
44
Q53840_SORCE
(Q53840)
Jump to Soraph_00080
[query] 38 - 3130 (3190)
[subject] 3670 - 6785 (8817)
(9 hsp)
0.0 2497   48% Soraphen polyketide synthase B sorB Sorangium cellulosum
Polyangium cellulosum
45
Q52V46_9ACTO
(Q52V46)
[query] 38 - 3108 (3190)
[subject] 5005 - 8068 (8147)
(9 hsp)
0.0 2471   50% Polyketide synthase type I Streptomyces aizunensis
46
A0FCL3_STRVO
(A0FCL3)
Jump to Merid_00040
[query] 38 - 3110 (3190)
[subject] 2949 - 5929 (11604)
(10 hsp)
0.0 2459   50% MerC merC Streptomyces violaceoniger
47
D9T6X1_MICAI
(D9T6X1)
[query] 8 - 3188 (3190)
[subject] 3 - 3163 (3165)
0.0 2424   49% Beta-ketoacyl synthase Micau_2471 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
48
A0ACI1_STRAM
(A0ACI1)
[query] 9 - 3176 (3190)
[subject] 4 - 3148 (3157)
0.0 2421   49% Putative modular polyketide synthase SAMR0475 Streptomyces ambofaciens ATCC 23877
49
E8S0B8_MICSL
(E8S0B8)
[query] 8 - 3188 (3190)
[subject] 3 - 3163 (3165)
0.0 2416   49% Beta-ketoacyl synthase ML5_5891 Micromonospora sp. (strain L5)
50
D1GLV8_9ACTO
(D1GLV8)
Jump to Strply_00300
[query] 2 - 2464 (3190)
[subject] 14 - 2538 (3479)
(4 hsp)
0.0 2409   55% Polyketide synthase type I slgA2 Streptomyces lydicus
51
D7C2C2_STRBB
(D7C2C2)
[query] 41 - 3180 (3190)
[subject] 1694 - 4816 (4821)
(4 hsp)
0.0 2408   49% Modular polyketide synthase pks3-3
SBI_00655
Streptomyces bingchenggensis (strain BCW-1)
52
Q52V44_9ACTO
(Q52V44)
[query] 40 - 3109 (3190)
[subject] 1831 - 4862 (6751)
(8 hsp)
0.0 2407   50% Polyketide synthase type I Streptomyces aizunensis
53
Q9ALM3_9PSEU
(Q9ALM3)
Jump to Spino_00200
[query] 35 - 3102 (3190)
[subject] 1781 - 4843 (4928)
(5 hsp)
0.0 2404   49% Polyketide synthase extender modules 5-7 spnD Saccharopolyspora spinosa
54
Q3S865_9ACTO
(Q3S865)
Jump to Conca_00050
[query] 12 - 3114 (3190)
[subject] 31 - 3197 (4825)
(2 hsp)
0.0 2394   50% Modular polyketide synthase Streptomyces neyagawaensis
55
Q27W58_STRVO
(Q27W58)
Jump to Niger_00170
[query] 8 - 3108 (3190)
[subject] 4 - 3147 (4787)
(3 hsp)
0.0 2382   46% NigAVII Streptomyces violaceoniger
56
E0KCN8_STRVO
(E0KCN8)
[query] 37 - 3102 (3190)
[subject] 1626 - 4725 (4810)
(2 hsp)
0.0 2363   47% 6-deoxyerythronolide-B synthase., 6-methylsalicylic acid synthase StrviDRAFT_0013 Streptomyces violaceusniger Tu 4113 2.3.1.165

2.3.1.94
57
F1DI32_9ACTO
(F1DI32)
[query] 5 - 2465 (3190)
[subject] 12 - 2468 (3378)
(4 hsp)
0.0 2363   54% TrdAII Streptomyces sp. SCSIO1666
58
Q93HJ5_STRAW
(Q93HJ5)
Jump to Oligo_00080
[query] 35 - 3108 (3190)
[subject] 1007 - 3970 (6146)
(8 hsp)
0.0 2361   49% Modular polyketide synthase olmA1
SAV2899
SAV_2899
Streptomyces avermitilis
59
D7P614_CHOCO
(D7P614)
[query] 38 - 3106 (3190)
[subject] 16 - 3110 (6610)
(5 hsp)
0.0 2359   47% TugD tugD Chondromyces crocatus
60
B4VBW0_9ACTO
(B4VBW0)
[query] 38 - 3111 (3190)
[subject] 178 - 3237 (10873)
(8 hsp)
0.0 2355   49% Polyketide synthase type I SSAG_05337 Streptomyces sp. Mg1
61
D6C474_9ACTO
(D6C474)
Jump to Meili_00270
[query] 8 - 3108 (3190)
[subject] 5 - 3074 (5277)
(4 hsp)
0.0 2354   49% Modular polyketide synthase meiA4 Streptomyces nanchangensis
62
A4F7P1_SACEN
(A4F7P1)
[query] 9 - 3175 (3190)
[subject] 9 - 2949 (3171)
0.0 2353   47% EryAIII Erythromycin polyketide synthase modules 5 and 6 eryAIII
SACE_0724
Saccharopolyspora erythraea (strain NRRL 23338)
63
Q5UNP4_SACER
(Q5UNP4)
[query] 9 - 3175 (3190)
[subject] 9 - 2949 (3171)
0.0 2353   47% EryAIII eryAIII Saccharopolyspora erythraea
Streptomyces erythraeus
64
D3Y1I4_9ACTO
(D3Y1I4)
[query] 9 - 2465 (3190)
[subject] 3 - 2455 (3365)
(4 hsp)
0.0 2350   54% TamAII Streptomyces sp. 307-9
65
C9YYI0_STRSW
(C9YYI0)
[query] 13 - 3110 (3190)
[subject] 1 - 3173 (4799)
(2 hsp)
0.0 2337   49% Putative type I polyketide synthase SCAB_83891 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
66
A0ACI0_STRAM
(A0ACI0)
[query] 7 - 3121 (3190)
[subject] 12 - 3056 (6333)
(4 hsp)
0.0 2333   49% Putative modular polyketide synthase SAMR0474 Streptomyces ambofaciens ATCC 23877
67
Q6W5P9_9ACTO
(Q6W5P9)
Jump to FR008_00170
[query] 6 - 2463 (3190)
[subject] 1 - 2487 (5541)
(7 hsp)
0.0 2327   54% FscB fscB Streptomyces sp. FR-008
68
A4F7N8_SACEN
(A4F7N8)
[query] 34 - 3111 (3190)
[subject] 553 - 3470 (3545)
(5 hsp)
0.0 2323   47% EryAI Erythromycin polyketide synthase modules 1 and 2 eryAI
SACE_0721
Saccharopolyspora erythraea (strain NRRL 23338)
69
Q5UNP6_SACER
(Q5UNP6)
[query] 34 - 3111 (3190)
[subject] 553 - 3470 (3545)
(5 hsp)
0.0 2323   47% EryAI eryAI Saccharopolyspora erythraea
Streptomyces erythraeus
70
F1ADM1_9ACTO
(F1ADM1)
[query] 10 - 2474 (3190)
[subject] 30 - 2562 (3511)
(4 hsp)
0.0 2322   54% BafAIV Streptomyces lohii
71
ERYA1_SACER
(Q03131)
[query] 34 - 3111 (3190)
[subject] 500 - 3416 (3491)
(5 hsp)
0.0 2320   47% Erythronolide synthase, modules 1 and 2
6-deoxyerythronolide B synthase I
DEBS 1
ORF 1
eryA Saccharopolyspora erythraea
Streptomyces erythraeus
2.3.1.94
72
D3U9Y9_9ACTO
(D3U9Y9)
[query] 5 - 2465 (3190)
[subject] 22 - 2537 (3405)
(4 hsp)
0.0 2315   54% Type I polyketide synthase sfaI Streptomyces flaveolus
73
Q0ILD4_9ACTO
(Q0ILD4)
[query] 38 - 3107 (3190)
[subject] 1006 - 3982 (6148)
(8 hsp)
0.0 2309   49% NlmA1 nlmA1 Streptomyces nanchangensis
74
E2Q518_STRCL
(E2Q518)
[query] 3 - 2468 (3190)
[subject] 11 - 2590 (3596)
(4 hsp)
0.0 2309   53% Modular polyketide synthase SCLAV_0012 Streptomyces clavuligerus ATCC 27064
75
C6WNU8_ACTMD
(C6WNU8)
[query] 8 - 3110 (3190)
[subject] 3 - 3025 (3092)
0.0 2308   48% Short-chain dehydrogenase/reductase SDR Amir_2682 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
76
Q1WEK8_9ACTO
(Q1WEK8)
[query] 38 - 2545 (3190)
[subject] 1728 - 4204 (7102)
(10 hsp)
0.0 2304   53% Polyketide synthase merB Streptomyces sp. NRRL 30748
77
B1W4J2_STRGG
(B1W4J2)
[query] 6 - 3114 (3190)
[subject] 1 - 3180 (5343)
(5 hsp)
0.0 2300   47% Putative type-I PKS pks2-2
SGR_6180
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
78
E4NJF4_KITSK
(E4NJF4)
[query] 14 - 2474 (3190)
[subject] 3 - 2488 (3436)
(4 hsp)
0.0 2297   55% Modular polyketide synthase BFAS4 bfmA4
KSE_73470
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
79
D9T6W1_MICAI
(D9T6W1)
[query] 38 - 3112 (3190)
[subject] 1773 - 4815 (6415)
(6 hsp)
0.0 2296   48% Beta-ketoacyl synthase Micau_2461 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
80
Q8GBX6_SORCE
(Q8GBX6)
[query] 9 - 3145 (3190)
[subject] 6 - 3169 (5017)
(4 hsp)
0.0 2294   46% Polyketide synthase spiH Sorangium cellulosum
Polyangium cellulosum
81
A4F5C7_SORCE
(A4F5C7)
[query] 16 - 3145 (3190)
[subject] 1 - 3157 (5005)
(4 hsp)
0.0 2289   46% Polyketide synthase spiH Sorangium cellulosum
Polyangium cellulosum
82
D5ZU03_9ACTO
(D5ZU03)
[query] 38 - 2469 (3190)
[subject] 1473 - 3774 (4652)
(8 hsp)
0.0 2287   55% Type I modular polyketide synthase SSFG_00092 Streptomyces ghanaensis ATCC 14672
83
A0FCL2_STRVO
(A0FCL2)
Jump to Merid_00030
[query] 38 - 2545 (3190)
[subject] 1733 - 4251 (7178)
(10 hsp)
0.0 2286   53% MerB merB Streptomyces violaceoniger
84
E0KRC7_STRVO
(E0KRC7)
[query] 38 - 2545 (3190)
[subject] 190 - 2665 (5559)
(9 hsp)
0.0 2281   52% Beta-ketoacyl synthase StrviDRAFT_5204 Streptomyces violaceusniger Tu 4113
85
D7P5Z5_SORCE
(D7P5Z5)
[query] 46 - 3137 (3190)
[subject] 1 - 3199 (6663)
(6 hsp)
0.0 2275   47% TgaC tgaC Sorangium cellulosum
Polyangium cellulosum
86
E0KBI1_STRVO
(E0KBI1)
[query] 7 - 2481 (3190)
[subject] 2 - 2505 (3456)
(4 hsp)
0.0 2274   52% Acyl transferase StrviDRAFT_0196 Streptomyces violaceusniger Tu 4113
87
Q9KIV3_STRAT
(Q9KIV3)
[query] 6 - 2480 (3190)
[subject] 1 - 2487 (3816)
(4 hsp)
0.0 2271   53% 8,8a-deoxyoleandolide synthase 2 oleAII Streptomyces antibioticus
88
A0ACH1_STRAM
(A0ACH1)
[query] 38 - 3108 (3190)
[subject] 3589 - 6568 (8154)
(5 hsp)
0.0 2270   48% Putative polyketide synthase B SAMR0465 Streptomyces ambofaciens ATCC 23877
89
B6ZIR3_STRPT
(B6ZIR3)
Jump to Pladi_00020
[query] 38 - 2462 (3190)
[subject] 3661 - 6105 (7026)
(10 hsp)
0.0 2262   53% Polyketide synthase pldAII Streptomyces platensis
90
F1ADL8_9ACTO
(F1ADL8)
[query] 20 - 3119 (3190)
[subject] 572 - 3717 (4884)
(8 hsp)
0.0 2260   47% BafAI Streptomyces lohii
91
A0FCL1_STRVO
(A0FCL1)
Jump to Merid_00020
[query] 38 - 2462 (3190)
[subject] 1066 - 3381 (5721)
(7 hsp)
0.0 2259   55% MerA merA Streptomyces violaceoniger
92
Q1WEK9_9ACTO
(Q1WEK9)
[query] 38 - 2475 (3190)
[subject] 1060 - 3389 (5712)
(7 hsp)
0.0 2253   54% Polyketide synthase merA Streptomyces sp. NRRL 30748
93
D9W5P0_9ACTO
(D9W5P0)
[query] 7 - 2465 (3190)
[subject] 4 - 2466 (3748)
(4 hsp)
0.0 2246   54% Modular polyketide synthase SSNG_07470 Streptomyces sp. C
94
Q6MZ72_MYCUA
(Q6MZ72)
Jump to MUP_00320
[query] 36 - 3148 (3190)
[subject] 1814 - 4921 (14130)
(19 hsp)
0.0 2235   44% Type I modular polyketide synthase mlsB
MUP032c
Mycobacterium ulcerans (strain Agy99)
95
ERYA3_SACER
(Q03133)
[query] 9 - 3175 (3190)
[subject] 9 - 2950 (3172)
0.0 2233   47% Erythronolide synthase, modules 5 and 6
6-deoxyerythronolide B synthase III
DEBS 3
ORF 3
eryA Saccharopolyspora erythraea
Streptomyces erythraeus
2.3.1.94
96
Q0ILD3_9ACTO
(Q0ILD3)
[query] 10 - 3102 (3190)
[subject] 5 - 2979 (4799)
(5 hsp)
0.0 2229   47% NlmA2 nlmA2 Streptomyces nanchangensis
97
E0KN03_STRVO
(E0KN03)
[query] 38 - 2470 (3190)
[subject] 1017 - 3342 (3735)
(5 hsp)
0.0 2219   54% 6-deoxyerythronolide-B synthase., Mycocerosate synthase StrviDRAFT_3962 Streptomyces violaceusniger Tu 4113 2.3.1.111

2.3.1.94
98
Q83X69_STRRO
(Q83X69)
[query] 27 - 3148 (3190)
[subject] 576 - 3599 (3651)
(5 hsp)
0.0 2210   48% Lankamycin synthase LkmAI lkmAI Streptomyces rochei
Streptomyces parvullus
99
B4VAJ6_9ACTO
(B4VAJ6)
[query] 38 - 2518 (3190)
[subject] 1015 - 3434 (3605)
(5 hsp)
0.0 2210   52% Polyketide synthase subunit SSAG_04835 Streptomyces sp. Mg1
100
Q5SFB4_STRBI
(Q5SFB4)
Jump to Chalc_00210
[query] 38 - 2518 (3190)
[subject] 1062 - 3486 (4441)
(6 hsp)
0.0 2205   52% Polyketide synthase subunit chmGI Streptomyces bikiniensis
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
Q93NW7_9ACTO
(Q93NW7)
[query] 1 - 3190 (3190)
[subject] 1 - 3190 (3190)
0.0 6271   100%
Product
AmphB
Gene
amphB
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
3uniprot[Pubmed] 20696392
Structural and functional analysis of A-type ketoreductases from the amphotericin modular polyketide synthase.(Structure) [2010]
[pubmed all]
2
Q9L4W4_9ACTO
(Q9L4W4)
Jump to Nysta_00140
[query] 1 - 3190 (3190)
[subject] 1 - 3192 (3192)
0.0 4622   78%
Product
NysB
Gene
nysB
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
3
D2CKM3_PSEAH
(D2CKM3)
[query] 3 - 3190 (3190)
[subject] 2 - 3175 (3175)
0.0 4013   70%
Product
CppB
Gene
cppB
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
4
Q93NX9_9ACTO
(Q93NX9)
Jump to Amph_00040
[query] 37 - 3112 (3190)
[subject] 3315 - 6378 (9510)
(7 hsp)
0.0 3261   61%
Product
AmphI
Gene
amphI
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
5
Q9L4X3_9ACTO
(Q9L4X3)
Jump to Nysta_00050
[query] 37 - 3113 (3190)
[subject] 3356 - 6428 (9477)
(8 hsp)
0.0 3114   60%
Product
NysI
Gene
nysI
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
6
D2CKL5_PSEAH
(D2CKL5)
[query] 37 - 3113 (3190)
[subject] 3336 - 6410 (9499)
(7 hsp)
0.0 3101   58%
Product
CppI
Gene
cppI
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
7
D7BRE1_STRBB
(D7BRE1)
[query] 38 - 3112 (3190)
[subject] 451 - 3511 (5139)
(4 hsp)
0.0 3083   56%
Product
Modular polyketide synthase
Gene
SBI_01983
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
8
F1CLA9_9ACTO
(F1CLA9)
[query] 38 - 3114 (3190)
[subject] 3323 - 6387 (9498)
(7 hsp)
0.0 3033   57%
Product
ScnS2
Gene
scnS2
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
9
Q9EWA1_9ACTO
(Q9EWA1)
Jump to Pimar_00070
[query] 38 - 3123 (3190)
[subject] 3331 - 6402 (9507)
(7 hsp)
0.0 3019   57%
Product
PimS2 protein
Gene
pimS2
Organism
Streptomyces natalensis
1uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
11
Q6W5P6_9ACTO
(Q6W5P6)
Jump to FR008_00200
[query] 38 - 3111 (3190)
[subject] 3342 - 6407 (9550)
(7 hsp)
0.0 2972   56%
Product
FscD
Gene
fscD
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
13
Q52V51_9ACTO
(Q52V51)
[query] 8 - 3102 (3190)
[subject] 3 - 3143 (3227)
0.0 2892   54%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
15
C9YYI3_STRSW
(C9YYI3)
[query] 9 - 3126 (3190)
[subject] 6 - 3203 (5001)
(4 hsp)
0.0 2867   54%
Product
Putative type I polyketide synthase
Gene
SCAB_83921
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
16
Q3S869_9ACTO
(Q3S869)
Jump to Conca_00080
[query] 9 - 3126 (3190)
[subject] 6 - 3202 (5006)
(4 hsp)
0.0 2850   54%
Product
Modular polyketide synthase
Gene
 
Organism
Streptomyces neyagawaensis
1uniprot[Pubmed] 16207901
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005]
18
C9YYI1_STRSW
(C9YYI1)
[query] 9 - 3111 (3190)
[subject] 4 - 3111 (4970)
(4 hsp)
0.0 2819   55%
Product
Putative type I polyketide synthase
Gene
SCAB_83901
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
20
Q3S864_9ACTO
(Q3S864)
Jump to Conca_00060
[query] 9 - 3111 (3190)
[subject] 4 - 3111 (4970)
(6 hsp)
0.0 2810   55%
Product
Nodular polyketide synthase
Gene
 
Organism
Streptomyces neyagawaensis
1uniprot[Pubmed] 16207901
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005]
21
E0D202_9ACTO
(E0D202)
Jump to FD891_00010
[query] 38 - 3126 (3190)
[subject] 1037 - 4089 (7480)
(9 hsp)
0.0 2777   53%
Product
Polyketide synthase
Gene
gfsA
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
23
E4NJF2_KITSK
(E4NJF2)
[query] 6 - 3108 (3190)
[subject] 1 - 3127 (5004)
(4 hsp)
0.0 2741   54%
Product
Modular polyketide synthase BFAS2
Gene
bfmA2
KSE_73450
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
24
Q93HJ2_STRAW
(Q93HJ2)
Jump to Oligo_00110
[query] 6 - 3120 (3190)
[subject] 2 - 3086 (4685)
(2 hsp)
0.0 2718   53%
Product
Modular polyketide synthase
Gene
olmA6
SAV2896
SAV_2896
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
25
B1W487_STRGG
(B1W487)
[query] 7 - 3114 (3190)
[subject] 3 - 3105 (3188)
(2 hsp)
0.0 2712   52%
Product
Putative type-I PKS
Gene
pks1-3
SGR_6075
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
27
Q93H83_STRAW
(Q93H83)
[query] 7 - 3120 (3190)
[subject] 3 - 3067 (3352)
0.0 2640   51%
Product
Modular polyketide synthase
Gene
pteA5
SAV415
SAV_415
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
29
Q68BG5_STRHA
(Q68BG5)
Jump to Halsto_00010
[query] 35 - 3182 (3190)
[subject] 1016 - 4188 (4194)
(5 hsp)
0.0 2634   50%
Product
Type I polyketide synthase
Gene
hlsA
Organism
Streptomyces halstedii
1uniprot
Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004]
31
D7C2C3_STRBB
(D7C2C3)
[query] 38 - 2995 (3190)
[subject] 1870 - 4852 (4868)
(5 hsp)
0.0 2608   53%
Product
Modular polyketide synthase
Gene
pks3-4
SBI_00656
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
33
Q9KIV4_STRAT
(Q9KIV4)
[query] 37 - 3190 (3190)
[subject] 1060 - 4149 (4150)
(5 hsp)
0.0 2578   51%
Product
8,8a-deoxyoleandolide synthase 1
Gene
oleAI
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 10908114 [Medline] 20363406
Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin.(J. Antibiot.) [2000]
38
D3Y1I3_9ACTO
(D3Y1I3)
[query] 39 - 3102 (3190)
[subject] 1024 - 3996 (5828)
(7 hsp)
0.0 2541   50%
Product
TamAI
Gene
 
Organism
Streptomyces sp. 307-9
1uniprot[Pubmed] 20127927
Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010]
39
Q9ALM4_9PSEU
(Q9ALM4)
Jump to Spino_00190
[query] 7 - 3109 (3190)
[subject] 2 - 3093 (3170)
(2 hsp)
0.0 2541   51%
Product
Polyketide synthase extender modules 3-4
Gene
spnC
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
40
Q1WEK7_9ACTO
(Q1WEK7)
[query] 37 - 3122 (3190)
[subject] 2952 - 5943 (7968)
(6 hsp)
0.0 2540   51%
Product
Polyketide synthase
Gene
merC
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
41
F1DI31_9ACTO
(F1DI31)
[query] 38 - 3102 (3190)
[subject] 1023 - 3997 (5829)
(7 hsp)
0.0 2534   50%
Product
TrdAI
Gene
 
Organism
Streptomyces sp. SCSIO1666
1uniprot[Pubmed] 21329667
Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011]
42
Q93H84_STRAW
(Q93H84)
[query] 22 - 3109 (3190)
[subject] 2 - 3029 (6145)
(2 hsp)
0.0 2533   50%
Product
Modular polyketide synthase
Gene
pteA4
SAV416
SAV_416
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
43
D1GLV9_9ACTO
(D1GLV9)
Jump to Strply_00310
[query] 32 - 3117 (3190)
[subject] 1062 - 4179 (6171)
(7 hsp)
0.0 2500   49%
Product
Polyketide synthase type I
Gene
slgA1
Organism
Streptomyces lydicus
1uniprot
Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009]
44
Q53840_SORCE
(Q53840)
Jump to Soraph_00080
[query] 38 - 3130 (3190)
[subject] 3670 - 6785 (8817)
(9 hsp)
0.0 2497   48%
Product
Soraphen polyketide synthase B
Gene
sorB
Organism
Sorangium cellulosum
Polyangium cellulosum
1uniprot[Pubmed] 7601830 [Medline] 95325306
A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes.(J. Bacteriol.) [1995]
2uniprot[Pubmed] 12039053 [Medline] 22035375
Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.(Gene) [2002]
[pubmed all]
45
Q52V46_9ACTO
(Q52V46)
[query] 38 - 3108 (3190)
[subject] 5005 - 8068 (8147)
(9 hsp)
0.0 2471   50%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
46
A0FCL3_STRVO
(A0FCL3)
Jump to Merid_00040
[query] 38 - 3110 (3190)
[subject] 2949 - 5929 (11604)
(10 hsp)
0.0 2459   50%
Product
MerC
Gene
merC
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
48
A0ACI1_STRAM
(A0ACI1)
[query] 9 - 3176 (3190)
[subject] 4 - 3148 (3157)
0.0 2421   49%
Product
Putative modular polyketide synthase
Gene
SAMR0475
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
50
D1GLV8_9ACTO
(D1GLV8)
Jump to Strply_00300
[query] 2 - 2464 (3190)
[subject] 14 - 2538 (3479)
(4 hsp)
0.0 2409   55%
Product
Polyketide synthase type I
Gene
slgA2
Organism
Streptomyces lydicus
1uniprot
Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009]
51
D7C2C2_STRBB
(D7C2C2)
[query] 41 - 3180 (3190)
[subject] 1694 - 4816 (4821)
(4 hsp)
0.0 2408   49%
Product
Modular polyketide synthase
Gene
pks3-3
SBI_00655
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
52
Q52V44_9ACTO
(Q52V44)
[query] 40 - 3109 (3190)
[subject] 1831 - 4862 (6751)
(8 hsp)
0.0 2407   50%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
53
Q9ALM3_9PSEU
(Q9ALM3)
Jump to Spino_00200
[query] 35 - 3102 (3190)
[subject] 1781 - 4843 (4928)
(5 hsp)
0.0 2404   49%
Product
Polyketide synthase extender modules 5-7
Gene
spnD
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
54
Q3S865_9ACTO
(Q3S865)
Jump to Conca_00050
[query] 12 - 3114 (3190)
[subject] 31 - 3197 (4825)
(2 hsp)
0.0 2394   50%
Product
Modular polyketide synthase
Gene
 
Organism
Streptomyces neyagawaensis
1uniprot[Pubmed] 16207901
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005]
55
Q27W58_STRVO
(Q27W58)
Jump to Niger_00170
[query] 8 - 3108 (3190)
[subject] 4 - 3147 (4787)
(3 hsp)
0.0 2382   46%
Product
NigAVII
Gene
 
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17584617
Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137.(Chem. Biol.) [2007]
57
F1DI32_9ACTO
(F1DI32)
[query] 5 - 2465 (3190)
[subject] 12 - 2468 (3378)
(4 hsp)
0.0 2363   54%
Product
TrdAII
Gene
 
Organism
Streptomyces sp. SCSIO1666
1uniprot[Pubmed] 21329667
Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011]
58
Q93HJ5_STRAW
(Q93HJ5)
Jump to Oligo_00080
[query] 35 - 3108 (3190)
[subject] 1007 - 3970 (6146)
(8 hsp)
0.0 2361   49%
Product
Modular polyketide synthase
Gene
olmA1
SAV2899
SAV_2899
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
59
D7P614_CHOCO
(D7P614)
[query] 38 - 3106 (3190)
[subject] 16 - 3110 (6610)
(5 hsp)
0.0 2359   47%
Product
TugD
Gene
tugD
Organism
Chondromyces crocatus
1uniprot[Pubmed] 20416506
Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010]
61
D6C474_9ACTO
(D6C474)
Jump to Meili_00270
[query] 8 - 3108 (3190)
[subject] 5 - 3074 (5277)
(4 hsp)
0.0 2354   49%
Product
Modular polyketide synthase
Gene
meiA4
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
62
A4F7P1_SACEN
(A4F7P1)
[query] 9 - 3175 (3190)
[subject] 9 - 2949 (3171)
0.0 2353   47%
Product
EryAIII Erythromycin polyketide synthase modules 5 and 6
Gene
eryAIII
SACE_0724
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
63
Q5UNP4_SACER
(Q5UNP4)
[query] 9 - 3175 (3190)
[subject] 9 - 2949 (3171)
0.0 2353   47%
Product
EryAIII
Gene
eryAIII
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 15496466
Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
2uniprot[Pubmed] 16844787
The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase.(Proc. Natl. Acad. Sci. U.S.A.) [2006]
[pubmed all]
64
D3Y1I4_9ACTO
(D3Y1I4)
[query] 9 - 2465 (3190)
[subject] 3 - 2455 (3365)
(4 hsp)
0.0 2350   54%
Product
TamAII
Gene
 
Organism
Streptomyces sp. 307-9
1uniprot[Pubmed] 20127927
Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010]
65
C9YYI0_STRSW
(C9YYI0)
[query] 13 - 3110 (3190)
[subject] 1 - 3173 (4799)
(2 hsp)
0.0 2337   49%
Product
Putative type I polyketide synthase
Gene
SCAB_83891
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
66
A0ACI0_STRAM
(A0ACI0)
[query] 7 - 3121 (3190)
[subject] 12 - 3056 (6333)
(4 hsp)
0.0 2333   49%
Product
Putative modular polyketide synthase
Gene
SAMR0474
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
67
Q6W5P9_9ACTO
(Q6W5P9)
Jump to FR008_00170
[query] 6 - 2463 (3190)
[subject] 1 - 2487 (5541)
(7 hsp)
0.0 2327   54%
Product
FscB
Gene
fscB
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
68
A4F7N8_SACEN
(A4F7N8)
[query] 34 - 3111 (3190)
[subject] 553 - 3470 (3545)
(5 hsp)
0.0 2323   47%
Product
EryAI Erythromycin polyketide synthase modules 1 and 2
Gene
eryAI
SACE_0721
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
69
Q5UNP6_SACER
(Q5UNP6)
[query] 34 - 3111 (3190)
[subject] 553 - 3470 (3545)
(5 hsp)
0.0 2323   47%
Product
EryAI
Gene
eryAI
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 15496466
Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
71
ERYA1_SACER
(Q03131)
[query] 34 - 3111 (3190)
[subject] 500 - 3416 (3491)
(5 hsp)
0.0 2320   47%
Product
Erythronolide synthase, modules 1 and 2
6-deoxyerythronolide B synthase I
DEBS 1
ORF 1
Gene
eryA
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 2024119 [Medline] 91220065
Modular organization of genes required for complex polyketide biosynthesis.(Science) [1991]
2uniprot[Pubmed] 8386127 [Medline] 93231529
IS1136, an insertion element in the erythromycin gene cluster of Saccharopolyspora erythraea.(Gene) [1993]
[pubmed all]
72
D3U9Y9_9ACTO
(D3U9Y9)
[query] 5 - 2465 (3190)
[subject] 22 - 2537 (3405)
(4 hsp)
0.0 2315   54%
Product
Type I polyketide synthase
Gene
sfaI
Organism
Streptomyces flaveolus
1uniprot
Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010]
74
E2Q518_STRCL
(E2Q518)
[query] 3 - 2468 (3190)
[subject] 11 - 2590 (3596)
(4 hsp)
0.0 2309   53%
Product
Modular polyketide synthase
Gene
SCLAV_0012
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
75
C6WNU8_ACTMD
(C6WNU8)
[query] 8 - 3110 (3190)
[subject] 3 - 3025 (3092)
0.0 2308   48%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2682
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
76
Q1WEK8_9ACTO
(Q1WEK8)
[query] 38 - 2545 (3190)
[subject] 1728 - 4204 (7102)
(10 hsp)
0.0 2304   53%
Product
Polyketide synthase
Gene
merB
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
77
B1W4J2_STRGG
(B1W4J2)
[query] 6 - 3114 (3190)
[subject] 1 - 3180 (5343)
(5 hsp)
0.0 2300   47%
Product
Putative type-I PKS
Gene
pks2-2
SGR_6180
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
78
E4NJF4_KITSK
(E4NJF4)
[query] 14 - 2474 (3190)
[subject] 3 - 2488 (3436)
(4 hsp)
0.0 2297   55%
Product
Modular polyketide synthase BFAS4
Gene
bfmA4
KSE_73470
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
81
A4F5C7_SORCE
(A4F5C7)
[query] 16 - 3145 (3190)
[subject] 1 - 3157 (5005)
(4 hsp)
0.0 2289   46%
Product
Polyketide synthase
Gene
spiH
Organism
Sorangium cellulosum
Polyangium cellulosum
1uniprot[Pubmed] 17317575
Spiroketal polyketide formation in Sorangium: Identification of the biosynthetic gene cluster for the highly cytotoxic spirangienes.(Chem. Biol.) [2007]
83
A0FCL2_STRVO
(A0FCL2)
Jump to Merid_00030
[query] 38 - 2545 (3190)
[subject] 1733 - 4251 (7178)
(10 hsp)
0.0 2286   53%
Product
MerB
Gene
merB
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
85
D7P5Z5_SORCE
(D7P5Z5)
[query] 46 - 3137 (3190)
[subject] 1 - 3199 (6663)
(6 hsp)
0.0 2275   47%
Product
TgaC
Gene
tgaC
Organism
Sorangium cellulosum
Polyangium cellulosum
1uniprot[Pubmed] 20416506
Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010]
87
Q9KIV3_STRAT
(Q9KIV3)
[query] 6 - 2480 (3190)
[subject] 1 - 2487 (3816)
(4 hsp)
0.0 2271   53%
Product
8,8a-deoxyoleandolide synthase 2
Gene
oleAII
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 10908114 [Medline] 20363406
Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin.(J. Antibiot.) [2000]
88
A0ACH1_STRAM
(A0ACH1)
[query] 38 - 3108 (3190)
[subject] 3589 - 6568 (8154)
(5 hsp)
0.0 2270   48%
Product
Putative polyketide synthase B
Gene
SAMR0465
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
89
B6ZIR3_STRPT
(B6ZIR3)
Jump to Pladi_00020
[query] 38 - 2462 (3190)
[subject] 3661 - 6105 (7026)
(10 hsp)
0.0 2262   53%
Product
Polyketide synthase
Gene
pldAII
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
91
A0FCL1_STRVO
(A0FCL1)
Jump to Merid_00020
[query] 38 - 2462 (3190)
[subject] 1066 - 3381 (5721)
(7 hsp)
0.0 2259   55%
Product
MerA
Gene
merA
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
92
Q1WEK9_9ACTO
(Q1WEK9)
[query] 38 - 2475 (3190)
[subject] 1060 - 3389 (5712)
(7 hsp)
0.0 2253   54%
Product
Polyketide synthase
Gene
merA
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
94
Q6MZ72_MYCUA
(Q6MZ72)
Jump to MUP_00320
[query] 36 - 3148 (3190)
[subject] 1814 - 4921 (14130)
(19 hsp)
0.0 2235   44%
Product
Type I modular polyketide synthase
Gene
mlsB
MUP032c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
2uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
[pubmed all]
95
ERYA3_SACER
(Q03133)
[query] 9 - 3175 (3190)
[subject] 9 - 2950 (3172)
0.0 2233   47%
Product
Erythronolide synthase, modules 5 and 6
6-deoxyerythronolide B synthase III
DEBS 3
ORF 3
Gene
eryA
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 2234082 [Medline] 91043075
An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea.(Nature) [1990]
2uniprot[Pubmed] 2024119 [Medline] 91220065
Modular organization of genes required for complex polyketide biosynthesis.(Science) [1991]
3uniprot[Pubmed] 1740151 [Medline] 92155230
6-deoxyerythronolide-B synthase 2 from Saccharopolyspora erythraea. Cloning of the structural gene, sequence analysis and inferred domain structure of the multifunctional enzyme.(Eur. J. Biochem.) [1992]
4uniprot[Pubmed] 1618327
Identification of DEBS 1, DEBS 2 and DEBS 3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase from Saccharopolyspora erythraea.(FEBS Lett.) [1992]
5uniprot[Pubmed] 11752428
Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: versatility from a unique substrate channel.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
6uniprot[Pubmed] 12379102
Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases.(Biochemistry) [2002]
[pubmed all]
98
Q83X69_STRRO
(Q83X69)
[query] 27 - 3148 (3190)
[subject] 576 - 3599 (3651)
(5 hsp)
0.0 2210   48%
Product
Lankamycin synthase LkmAI
Gene
lkmAI
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
100
Q5SFB4_STRBI
(Q5SFB4)
Jump to Chalc_00210
[query] 38 - 2518 (3190)
[subject] 1062 - 3486 (4441)
(6 hsp)
0.0 2205   52%
Product
Polyketide synthase subunit
Gene
chmGI
Organism
Streptomyces bikiniensis
1uniprot[Pubmed] 15561847
Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.(Antimicrob. Agents Chemother.) [2004]