| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
Q70HZ9_9ACTO (Q70HZ9) |
|
|
0.0 |
3125 |
100% |
|
- Product
- Borrelidin polyketide synthase, type I
- Gene
- borA4
- Organism
- Streptomyces parvulus
|
1uniprot[Pubmed] 15112998 Biosynthesis of the angiogenesis inhibitor borrelidin by Streptomyces parvulus Tu4055: cluster analysis and assignment of functions.(Chem. Biol.) [2004] | 2uniprot Evidence from engineered gene fusions for the repeated use of a module in a modular polyketide synthase";.(Chem. Commun. (Camb.)) [2003] |
|
3
|
Q70I00_9ACTO (Q70I00) |
|
(4 hsp) |
0.0 |
1495 |
89% |
|
- Product
- Borrelidin polyketide synthase, type I
- Gene
- borA3
- Organism
- Streptomyces parvulus
|
1uniprot[Pubmed] 15112998 Biosynthesis of the angiogenesis inhibitor borrelidin by Streptomyces parvulus Tu4055: cluster analysis and assignment of functions.(Chem. Biol.) [2004] | 2uniprot Evidence from engineered gene fusions for the repeated use of a module in a modular polyketide synthase";.(Chem. Commun. (Camb.)) [2003] |
|
4
|
A4FH83_SACEN (A4FH83) |
|
(5 hsp) |
0.0 |
1482 |
54% |
|
- Product
- Type I modular polyketide synthase
- Gene
- SACE_4139
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
5
|
Q5VKR4_SACER (Q5VKR4) |
|
(5 hsp) |
0.0 |
1482 |
54% |
|
- Product
- Type I PKS
- Gene
- pkeAIII
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15925898 A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004] |
|
6
|
D1GLV8_9ACTO (D1GLV8) |
|
(3 hsp) |
0.0 |
1482 |
55% |
|
- Product
- Polyketide synthase type I
- Gene
- slgA2
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
7
|
C5HV16_STRAT (C5HV16) |
|
(5 hsp) |
0.0 |
1482 |
56% |
|
- Product
- Polyketide synthase
- Gene
- idmN
- Organism
- Streptomyces antibioticus
|
1uniprot Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009] |
|
8
|
Q52V51_9ACTO (Q52V51) |
|
(2 hsp) |
0.0 |
1476 |
56% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
11
|
A4FH85_SACEN (A4FH85) |
|
(5 hsp) |
0.0 |
1467 |
54% |
|
- Product
- Type I modular polyketide synthase
- Gene
- SACE_4141
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
12
|
Q5VKQ3_SACER (Q5VKQ3) |
|
(5 hsp) |
0.0 |
1467 |
54% |
|
- Product
- Type I PKS
- Gene
- pkeAI
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15925898 A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004] |
|
13
|
F1DI32_9ACTO (F1DI32) |
|
(3 hsp) |
0.0 |
1457 |
54% |
|
- Product
- TrdAII
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
15
|
D3Y1I4_9ACTO (D3Y1I4) |
|
(3 hsp) |
0.0 |
1455 |
54% |
|
- Product
- TamAII
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
18
|
C5HV18_STRAT (C5HV18) |
|
(2 hsp) |
0.0 |
1447 |
56% |
|
- Product
- Polyketide synthase
- Gene
- idmP
- Organism
- Streptomyces antibioticus
|
1uniprot Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009] |
|
20
|
D7CC10_STRBB (D7CC10) |
|
|
0.0 |
1430 |
52% |
|
- Product
- Putative type I polyketide synthase
- Gene
- pks5-4
SBI_01384
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
21
|
B1W485_STRGG (B1W485) |
|
(5 hsp) |
0.0 |
1430 |
56% |
|
- Product
- Putative type-I PKS
- Gene
- pks1-1
SGR_6073
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
22
|
Q93HJ1_STRAW (Q93HJ1) |
|
(3 hsp) |
0.0 |
1424 |
55% |
|
- Product
- Modular polyketide synthase
- Gene
- olmA7
SAV2895 SAV_2895
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
23
|
Q1WEK8_9ACTO (Q1WEK8) |
|
(7 hsp) |
0.0 |
1421 |
54% |
|
- Product
- Polyketide synthase
- Gene
- merB
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
24
|
Q9KIV4_STRAT (Q9KIV4) |
|
(4 hsp) |
0.0 |
1415 |
53% |
|
- Product
- 8,8a-deoxyoleandolide synthase 1
- Gene
- oleAI
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 10908114 [Medline] 20363406 Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin.(J. Antibiot.) [2000] |
|
25
|
Q3S869_9ACTO (Q3S869) |
|
(4 hsp) |
0.0 |
1414 |
53% |
|
- Product
- Modular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
26
|
C9YYI3_STRSW (C9YYI3) |
|
(4 hsp) |
0.0 |
1414 |
53% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83921
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
27
|
A0FCL2_STRVO (A0FCL2) |
|
(7 hsp) |
0.0 |
1413 |
53% |
|
- Product
- MerB
- Gene
- merB
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
28
|
Q52V47_9ACTO (Q52V47) |
|
|
0.0 |
1412 |
53% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
30
|
Q846W6_STRCM (Q846W6) |
|
(3 hsp) |
0.0 |
1410 |
52% |
|
- Product
- Monensin polyketide synthase modules 11 and 12
- Gene
- monAVIII
- Organism
- Streptomyces cinnamonensis
|
1uniprot[Pubmed] 12940979 [Medline] 22823264 Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization.(Mol. Microbiol.) [2003] | 2uniprot The gene cluster for monensin biosynthesis. [1999] |
|
34
|
B1W487_STRGG (B1W487) |
|
(2 hsp) |
0.0 |
1407 |
53% |
|
- Product
- Putative type-I PKS
- Gene
- pks1-3
SGR_6075
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
35
|
Q9ALM4_9PSEU (Q9ALM4) |
|
(2 hsp) |
0.0 |
1407 |
54% |
|
- Product
- Polyketide synthase extender modules 3-4
- Gene
- spnC
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001] |
|
37
|
D1GLV9_9ACTO (D1GLV9) |
|
(6 hsp) |
0.0 |
1405 |
55% |
|
- Product
- Polyketide synthase type I
- Gene
- slgA1
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
40
|
B6ZIR3_STRPT (B6ZIR3) |
|
(7 hsp) |
0.0 |
1402 |
53% |
|
- Product
- Polyketide synthase
- Gene
- pldAII
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
41
|
C9YYI1_STRSW (C9YYI1) |
|
(4 hsp) |
0.0 |
1400 |
55% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCAB_83901
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
42
|
B1W490_STRGG (B1W490) |
|
(2 hsp) |
0.0 |
1400 |
54% |
|
- Product
- Putative type-I PKS
- Gene
- pks1-6
SGR_6078
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
43
|
D7BRE1_STRBB (D7BRE1) |
|
(4 hsp) |
0.0 |
1397 |
52% |
|
- Product
- Modular polyketide synthase
- Gene
- SBI_01983
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
44
|
B6ZIR4_STRPT (B6ZIR4) |
|
(3 hsp) |
0.0 |
1396 |
56% |
|
- Product
- Polyketide synthase
- Gene
- pldAIII
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
48
|
D7BSM1_STRBB (D7BSM1) |
|
(3 hsp) |
0.0 |
1393 |
53% |
|
- Product
- Type I polyketide synthase
- Gene
- nanA8
SBI_08400
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
49
|
D3Y1I3_9ACTO (D3Y1I3) |
|
(6 hsp) |
0.0 |
1391 |
54% |
|
- Product
- TamAI
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
50
|
Q7WTD6_9ACTO (Q7WTD6) |
|
(3 hsp) |
0.0 |
1390 |
53% |
|
- Product
- NanA8
- Gene
- nanA8
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12770825 [Medline] 22654646 A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin.(Chem. Biol.) [2003] |
|
52
|
E0D202_9ACTO (E0D202) |
|
(8 hsp) |
0.0 |
1389 |
53% |
|
- Product
- Polyketide synthase
- Gene
- gfsA
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
53
|
D7CC08_STRBB (D7CC08) |
|
(5 hsp) |
0.0 |
1387 |
52% |
|
- Product
- Putative type I polyketide synthase
- Gene
- pks5-2
SBI_01382
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
54
|
Q68BG5_STRHA (Q68BG5) |
|
(4 hsp) |
0.0 |
1387 |
53% |
|
- Product
- Type I polyketide synthase
- Gene
- hlsA
- Organism
- Streptomyces halstedii
|
1uniprot Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004] |
|
55
|
F1DI31_9ACTO (F1DI31) |
|
(6 hsp) |
0.0 |
1387 |
54% |
|
- Product
- TrdAI
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
56
|
Q3S864_9ACTO (Q3S864) |
|
(4 hsp) |
0.0 |
1384 |
54% |
|
- Product
- Nodular polyketide synthase
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
57
|
Q30CS2_STRAU (Q30CS2) |
|
(3 hsp) |
0.0 |
1383 |
51% |
|
- Product
- LipPks1
- Gene
- lipPks1
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 16723573 Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006] |
|
58
|
Q76KZ4_STRHA (Q76KZ4) |
|
(3 hsp) |
0.0 |
1382 |
50% |
|
- Product
- Polyketide synthase modules 5-6
- Gene
- vinP3
- Organism
- Streptomyces halstedii
|
1uniprot[Pubmed] 15112997 Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004] |
|
59
|
Q93HJ5_STRAW (Q93HJ5) |
|
(6 hsp) |
0.0 |
1375 |
56% |
|
- Product
- Modular polyketide synthase
- Gene
- olmA1
SAV2899 SAV_2899
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
60
|
Q1WEK7_9ACTO (Q1WEK7) |
|
(6 hsp) |
0.0 |
1370 |
55% |
|
- Product
- Polyketide synthase
- Gene
- merC
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
65
|
OL56_STRAT (Q07017) |
|
(2 hsp) |
0.0 |
1369 |
55% |
|
- Product
- Oleandomycin polyketide synthase, modules 5 and 6
- Gene
- orfB
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 8107683 [Medline] 94150470 Characterisation of a Streptomyces antibioticus gene encoding a type I polyketide synthase which has an unusual coding sequence.(Mol. Gen. Genet.) [1994] |
|
68
|
E4NJF2_KITSK (E4NJF2) |
|
(4 hsp) |
0.0 |
1367 |
54% |
|
- Product
- Modular polyketide synthase BFAS2
- Gene
- bfmA2
KSE_73450
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
69
|
Q93H83_STRAW (Q93H83) |
|
(2 hsp) |
0.0 |
1364 |
52% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA5
SAV415 SAV_415
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
71
|
E9LIP5_9ACTO (E9LIP5) |
|
(3 hsp) |
0.0 |
1362 |
52% |
|
- Product
- Putative modular polyketide synthase
- Gene
- tiaA2
- Organism
- Dactylosporangium aurantiacum subsp. hamdenensis
|
1uniprot[Pubmed] 21186805 Characterization of tiacumicin B biosynthetic gene cluster affording diversified tiacumicin analogues and revealing a tailoring dihalogenase.(J. Am. Chem. Soc.) [2011] |
|
72
|
Q846W5_STRCM (Q846W5) |
|
|
0.0 |
1360 |
50% |
|
- Product
- Monensin polyketide synthase module 10
- Gene
- monAVII
- Organism
- Streptomyces cinnamonensis
|
1uniprot[Pubmed] 12940979 [Medline] 22823264 Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization.(Mol. Microbiol.) [2003] | 2uniprot The gene cluster for monensin biosynthesis. [1999] |
|
73
|
A1YAM9_AMYOR (A1YAM9) |
|
(3 hsp) |
0.0 |
1360 |
55% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 17136886 Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006] |
|
74
|
A0FCL1_STRVO (A0FCL1) |
|
(6 hsp) |
0.0 |
1357 |
54% |
|
- Product
- MerA
- Gene
- merA
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
75
|
Q1WEK9_9ACTO (Q1WEK9) |
|
(6 hsp) |
0.0 |
1356 |
54% |
|
- Product
- Polyketide synthase
- Gene
- merA
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
76
|
Q331Q3_9ACTO (Q331Q3) |
|
|
0.0 |
1356 |
53% |
|
- Product
- Putative type I polyketide synthase
- Gene
- gerSIV
- Organism
- Streptomyces sp. KCTC 0041BP
|
1uniprot[Pubmed] 17053005 Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007] | 2uniprot Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006] |
|
77
|
B1W488_STRGG (B1W488) |
|
|
0.0 |
1353 |
49% |
|
- Product
- Putative type-I PKS
- Gene
- pks1-4
SGR_6076
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
78
|
A0ACH2_STRAM (A0ACH2) |
|
(3 hsp) |
0.0 |
1352 |
54% |
|
- Product
- Putative polyketide synthase B
- Gene
- SAMR0466
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
79
|
A0ACI0_STRAM (A0ACI0) |
|
(4 hsp) |
0.0 |
1352 |
54% |
|
- Product
- Putative modular polyketide synthase
- Gene
- SAMR0474
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
80
|
C0SMW4_9ACTO (C0SMW4) |
|
(12 hsp) |
0.0 |
1351 |
54% |
|
- Product
- Type I modular polyketide synthase
- Gene
- ttmJ
- Organism
- Streptomyces spiroverticillatus
|
1uniprot[Pubmed] 16707708 Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006] | 2uniprot[Pubmed] 18708355 Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008] | [pubmed all]
|
81
|
Q93HJ2_STRAW (Q93HJ2) |
|
(3 hsp) |
0.0 |
1348 |
53% |
|
- Product
- Modular polyketide synthase
- Gene
- olmA6
SAV2896 SAV_2896
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
82
|
A4FH82_SACEN (A4FH82) |
|
|
0.0 |
1344 |
53% |
|
- Product
- Type I PKS modular polyketide synthas
- Gene
- SACE_4138
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
83
|
Q5VKR3_SACER (Q5VKR3) |
|
|
0.0 |
1344 |
53% |
|
- Product
- Type I PKS
- Gene
-
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15925898 A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004] |
|
84
|
Q70HZ8_9ACTO (Q70HZ8) |
|
(2 hsp) |
0.0 |
1344 |
81% |
|
- Product
- Borrelidin polyketide synthase, type I
- Gene
- borA5
- Organism
- Streptomyces parvulus
|
1uniprot[Pubmed] 15112998 Biosynthesis of the angiogenesis inhibitor borrelidin by Streptomyces parvulus Tu4055: cluster analysis and assignment of functions.(Chem. Biol.) [2004] | 2uniprot Evidence from engineered gene fusions for the repeated use of a module in a modular polyketide synthase";.(Chem. Commun. (Camb.)) [2003] |
|
85
|
Q9L4W4_9ACTO (Q9L4W4) |
|
(2 hsp) |
0.0 |
1343 |
53% |
|
- Product
- NysB
- Gene
- nysB
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
88
|
Q93H84_STRAW (Q93H84) |
|
(4 hsp) |
0.0 |
1339 |
50% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA4
SAV416 SAV_416
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
89
|
A0ACI1_STRAM (A0ACI1) |
|
(2 hsp) |
0.0 |
1338 |
52% |
|
- Product
- Putative modular polyketide synthase
- Gene
- SAMR0475
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
91
|
Q5SFB1_STRBI (Q5SFB1) |
|
|
0.0 |
1332 |
52% |
|
- Product
- Polyketide synthase subunit
- Gene
- chmGIV
- Organism
- Streptomyces bikiniensis
|
1uniprot[Pubmed] 15561847 Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.(Antimicrob. Agents Chemother.) [2004] |
|
92
|
F1CT51_9ACTO (F1CT51) |
|
(6 hsp) |
0.0 |
1332 |
50% |
|
- Product
- GdmAI
- Gene
- gdmAI
- Organism
- Streptomyces autolyticus
|
1uniprot[Pubmed] 21544574 Streptomyces autolyticus JX-47 Large-Insert Bacterial Artificial Chromosome Library Construction and Identification of Clones Covering Geldanamycin Biosynthesis Gene Cluster.(Curr. Microbiol.) [2011] |
|
93
|
Q6W5P9_9ACTO (Q6W5P9) |
|
(5 hsp) |
0.0 |
1332 |
53% |
|
- Product
- FscB
- Gene
- fscB
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
94
|
B6ZIR2_STRPT (B6ZIR2) |
|
(7 hsp) |
0.0 |
1330 |
54% |
|
- Product
- Polyketide synthase
- Gene
- pldAI
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
97
|
Q53840_SORCE (Q53840) |
|
(7 hsp) |
0.0 |
1327 |
51% |
|
- Product
- Soraphen polyketide synthase B
- Gene
- sorB
- Organism
- Sorangium cellulosum
Polyangium cellulosum
|
1uniprot[Pubmed] 7601830 [Medline] 95325306 A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes.(J. Bacteriol.) [1995] | 2uniprot[Pubmed] 12039053 [Medline] 22035375 Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.(Gene) [2002] | [pubmed all]
|
99
|
B6ZK65_STRLS (B6ZK65) |
|
(5 hsp) |
0.0 |
1327 |
50% |
|
- Product
- Putative polyketide synthase
- Gene
- lsd12
- Organism
- Streptomyces lasaliensis
|
1uniprot[Pubmed] 19129623 Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009] | 2uniprot[Pubmed] 18710235 Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008] | [pubmed all]
|