| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
Q6W5R0_9ACTO (Q6W5R0) |
|
|
0.0 |
1920 |
100% |
|
- Product
- FscRIV
- Gene
- fscRIV
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
4
|
Q9L4W1_9ACTO (Q9L4W1) |
|
|
0.0 |
859 |
56% |
|
- Product
- NysRI
- Gene
- nysRI
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
5
|
D7C1U6_STRBB (D7C1U6) |
|
|
0.0 |
854 |
55% |
|
- Product
- Transcriptional regulator, LuxR family protein
- Gene
- SBI_09029
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
7
|
D2CKM6_PSEAH (D2CKM6) |
|
|
1e-155 |
555 |
45% |
|
- Product
- CppRI
- Gene
- cppRI
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 19697072 Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009] |
|
8
|
Q5QES7_9ACTO (Q5QES7) |
|
|
1e-127 |
461 |
40% |
|
- Product
- AmphRI
- Gene
-
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 15563836 Analysis and manipulation of amphotericin biosynthetic genes by means of modified phage KC515 transduction techniques.(Gene) [2004] |
|
11
|
Q5QEU4_9ACTO (Q5QEU4) |
|
|
4e-94 |
351 |
39% |
|
- Product
- Similar to AmphRI regulatory protein
- Gene
-
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 15563836 Analysis and manipulation of amphotericin biosynthetic genes by means of modified phage KC515 transduction techniques.(Gene) [2004] |
|
12
|
Q197Y9_9ACTO (Q197Y9) |
|
|
1e-67 |
263 |
33% |
|
- Product
- SalRI
- Gene
- salRI
- Organism
- Streptomyces albus
|
1uniprot[Pubmed] 18062184 Multiple regulatory genes in the salinomycin biosynthetic gene cluster of Streptomyces albus CCM 4719.(Folia Microbiol. (Praha)) [2007] |
|
16
|
B1W483_STRGG (B1W483) |
|
|
2e-51 |
209 |
30% |
|
- Product
- Putative LAL subfamily transcriptional regulator
- Gene
- SGR_6071
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
17
|
Q6F498_STRGR (Q6F498) |
|
|
2e-51 |
209 |
30% |
|
- Product
- Putative transcriptional regulator, similar to LAL subfamily
- Gene
- orf1-AdBS4
- Organism
- Streptomyces griseus
|
1uniprot[Pubmed] 15228534 DNA-binding specificity of AdpA, a transcriptional activator in the A-factor regulatory cascade in Streptomyces griseus.(Mol. Microbiol.) [2004] |
|
18
|
Q6W5R2_9ACTO (Q6W5R2) |
|
|
2e-50 |
206 |
32% |
|
- Product
- FscRII
- Gene
- fscRII
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
21
|
Q0QMP2_9ACTO (Q0QMP2) |
|
|
5e-47 |
194 |
32% |
|
- Product
- Regulator
- Gene
-
- Organism
- Streptomyces sp. Eco86
|
1uniprot[Pubmed] 16724457 Isolation and identification of three new 5-alkenyl-3,3(2H)-furanones from two streptomyces species using a genomic screening approach.(J. Antibiot.) [2006] |
|
24
|
D1GLT1_9ACTO (D1GLT1) |
|
|
4e-43 |
182 |
30% |
|
- Product
- LuxR-family transcriptional regulator
- Gene
- slgR2
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
26
|
Q9L4V9_9ACTO (Q9L4V9) |
|
|
4e-42 |
178 |
31% |
|
- Product
- NysRIII
- Gene
- nysRIII
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
29
|
Q5QES5_9ACTO (Q5QES5) |
|
|
9e-42 |
177 |
31% |
|
- Product
- AmphRIII
- Gene
-
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 15563836 Analysis and manipulation of amphotericin biosynthetic genes by means of modified phage KC515 transduction techniques.(Gene) [2004] |
|
30
|
Q197Z0_9ACTO (Q197Z0) |
|
|
2e-41 |
176 |
29% |
|
- Product
- SalRII
- Gene
- salRII
- Organism
- Streptomyces albus
|
1uniprot[Pubmed] 18062184 Multiple regulatory genes in the salinomycin biosynthetic gene cluster of Streptomyces albus CCM 4719.(Folia Microbiol. (Praha)) [2007] |
|
32
|
A4FDQ2_SACEN (A4FDQ2) |
|
|
9e-40 |
171 |
32% |
|
- Product
- LuxR-family transcriptional regulator
- Gene
- fscRIV
SACE_2899
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
33
|
D7C1U8_STRBB (D7C1U8) |
|
|
1e-39 |
170 |
31% |
|
- Product
- Transcriptional regulator, LuxR family protein
- Gene
- SBI_09031
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
38
|
D3Y1J2_9ACTO (D3Y1J2) |
|
|
9e-39 |
167 |
28% |
|
- Product
- TamH
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
39
|
F1DI40_9ACTO (F1DI40) |
|
|
2e-38 |
166 |
28% |
|
- Product
- TrdH
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
41
|
D8I5D8_AMYMU (D8I5D8) |
|
|
1e-37 |
163 |
29% |
|
- Product
- LuxR family transcriptional regulator fused with ATPase domain
- Gene
- AMED_1177
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
42
|
D2ATJ5_STRRD (D2ATJ5) |
|
|
3e-37 |
162 |
29% |
|
- Product
- ATPase-like protein
- Gene
- Sros_3795
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
44
|
E4N8L9_KITSK (E4N8L9) |
|
|
1e-36 |
160 |
28% |
|
- Product
- Putative regulatory protein
- Gene
- KSE_17260
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
45
|
C3VLY0_9ACTO (C3VLY0) |
|
|
9e-36 |
157 |
29% |
|
- Product
- LuxR-type transcriptional regulator
- Gene
- mlaH
- Organism
- Streptomyces sp. MP39-85
|
1uniprot[Pubmed] 19854930 Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010] |
|
47
|
C3VLV3_9ACTO (C3VLV3) |
|
|
3e-35 |
155 |
28% |
|
- Product
- LuxR-type transcriptional regulator
- Gene
- becH
- Organism
- Streptomyces sp. DSM 21069
|
1uniprot[Pubmed] 19875084 Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009] |
|
48
|
F8QZQ8_STRCX (F8QZQ8) |
|
|
1e-34 |
154 |
31% |
|
- Product
- LuxR family regulator
- Gene
- SchR2
- Organism
- Streptomyces chartreusis
|
1uniprot[Pubmed] 21173184 Characterization of the biosynthesis gene cluster for the pyrrole polyether antibiotic calcimycin (A23187) in Streptomyces chartreusis NRRL 3882.(Antimicrob. Agents Chemother.) [2011] |
|
51
|
A1YAL2_AMYOR (A1YAL2) |
|
|
1e-33 |
150 |
29% |
|
- Product
- Transcriptional regulator
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 17136886 Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006] |
|
55
|
Q93HJ8_STRAW (Q93HJ8) |
|
|
4e-33 |
148 |
28% |
|
- Product
- LuxR-family transcriptional regulator
LuxR-family transcriptional regulatory protein
- Gene
- olmRI
SAV2902 SAV_2902
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
56
|
E9LIP0_9ACTO (E9LIP0) |
|
|
1e-32 |
147 |
29% |
|
- Product
- Putative LuxR class regulator
- Gene
- tiaR1
- Organism
- Dactylosporangium aurantiacum subsp. hamdenensis
|
1uniprot[Pubmed] 21186805 Characterization of tiacumicin B biosynthetic gene cluster affording diversified tiacumicin analogues and revealing a tailoring dihalogenase.(J. Am. Chem. Soc.) [2011] |
|
57
|
E2PZ90_STRCL (E2PZ90) |
|
|
1e-32 |
147 |
26% |
|
- Product
- AmphRI-like transcriptional regulator
- Gene
- SCLAV_5278
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
59
|
D5MEG0_STRHY (D5MEG0) |
|
|
5e-32 |
145 |
30% |
|
- Product
- LuxR family transcriptional regulator
- Gene
- cltH
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 20154110 Identification and analysis of the biosynthetic gene cluster encoding the thiopeptide antibiotic cyclothiazomycin in Streptomyces hygroscopicus 10-22.(Appl. Environ. Microbiol.) [2010] |
|
60
|
Q3S885_9ACTO (Q3S885) |
|
|
8e-32 |
144 |
29% |
|
- Product
- Putative LuxR class regulator
- Gene
-
- Organism
- Streptomyces neyagawaensis
|
1uniprot[Pubmed] 16207901 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005] |
|
61
|
Q84G13_STRHY (Q84G13) |
|
|
1e-31 |
143 |
28% |
|
- Product
- GdmRII
- Gene
- gdmRII
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 12586396 [Medline] 22474162 Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003] |
|
62
|
Q52V61_9ACTO (Q52V61) |
|
|
3e-31 |
142 |
29% |
|
- Product
- Transcriptional regulator
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
63
|
Q52V76_9ACTO (Q52V76) |
|
|
4e-31 |
142 |
29% |
|
- Product
- Transcriptional regulator
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
66
|
Q49BD2_STRHY (Q49BD2) |
|
|
1e-29 |
137 |
28% |
|
- Product
- HbmRII
- Gene
- hbmRII
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 16085885 Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.(Appl. Environ. Microbiol.) [2005] |
|
69
|
Q9ZGI0_9ACTO (Q9ZGI0) |
|
|
5e-29 |
135 |
28% |
|
- Product
- Putative transcriptional activator PikD
- Gene
- pikD
- Organism
- Streptomyces venezuelae
|
1uniprot[Pubmed] 9770448 [Medline] 98445333 A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998] | 2uniprot[Pubmed] 9831532 [Medline] 99051447 Hydroxylation of macrolactones YC-17 and narbomycin is mediated by the pikC-encoded cytochrome P450 in Streptomyces venezuelae.(Chem. Biol.) [1998] | [pubmed all]
|
70
|
D2CKN2_PSEAH (D2CKN2) |
|
|
5e-29 |
135 |
28% |
|
- Product
- CppRV
- Gene
- cppRV
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 19697072 Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009] |
|
71
|
Q9K4E9_STRCO (Q9K4E9) |
|
(2 hsp) |
2e-28 |
132 |
32% |
|
- Product
- Putative transcriptional regulatory protein
- Gene
- SCO4263
- Organism
- Streptomyces coelicolor
|
1uniprot[Pubmed] 12000953 [Medline] 21996410 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002] |
|
72
|
D7C433_STRBB (D7C433) |
|
|
6e-28 |
131 |
28% |
|
- Product
- LuxR family transcriptional regulator
- Gene
- milR
SBI_00734
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
74
|
D2CKN3_PSEAH (D2CKN3) |
|
|
4e-27 |
129 |
32% |
|
- Product
- CppRVI
- Gene
- cppRVI
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 19697072 Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009] |
|
75
|
Q767F4_9ACTO (Q767F4) |
|
|
6e-27 |
128 |
39% |
|
- Product
- Putative transcriptional regulator
- Gene
-
- Organism
- Actinoplanes sp. A40644
|
1uniprot[Pubmed] 14763562 A relationship between the mevalonate pathway and isoprenoid production in actinomycetes.(J. Antibiot.) [2003] |
|
76
|
A4FDP3_SACEN (A4FDP3) |
|
|
7e-27 |
128 |
39% |
|
- Product
- LuxR-family transcriptional regulator
- Gene
- nysRI
SACE_2890
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
77
|
C6WQ76_ACTMD (C6WQ76) |
|
|
2e-26 |
127 |
33% |
|
- Product
- Transcriptional regulator, LuxR family
- Gene
- Amir_1178
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
79
|
Q9KID4_STRHY (Q9KID4) |
|
|
3e-26 |
126 |
28% |
|
- Product
- FkbN
- Gene
- fkbN
- Organism
- Streptomyces hygroscopicus subsp. ascomyceticus
|
1uniprot[Pubmed] 10863099 [Medline] 20323220 The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.(Gene) [2000] |
|
82
|
B6CWI5_STRRM (B6CWI5) |
|
|
1e-25 |
123 |
29% |
|
- Product
- ToyA
- Gene
- toyA
- Organism
- Streptomyces rimosus
|
1uniprot[Pubmed] 18721750 Deciphering deazapurine biosynthesis: pathway for pyrrolopyrimidine nucleosides toyocamycin and sangivamycin.(Chem. Biol.) [2008] |
|
84
|
D6C478_9ACTO (D6C478) |
|
|
3e-25 |
122 |
28% |
|
- Product
- LuxR-family transcriptional regulator
- Gene
- meiR
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12811466 [Medline] 22777186 Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003] | 2uniprot[Pubmed] 20348291 Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010] | [pubmed all]
|
85
|
F3NGB6_9ACTO (F3NGB6) |
|
|
3e-25 |
122 |
29% |
|
- Product
- Regulatory protein
- Gene
- SGM_2180
- Organism
- Streptomyces griseoaurantiacus M045
|
1uniprot[Pubmed] 21551298 Draft Genome Sequence of the Marine Bacterium Streptomyces griseoaurantiacus M045, Which Produces Novel Manumycin-Type Antibiotics with a pABA Core Component.(J. Bacteriol.) [2011] |
|
92
|
D7C1U7_STRBB (D7C1U7) |
|
|
7e-24 |
118 |
29% |
|
- Product
- Transcriptional regulator, luxR family protein
- Gene
- SBI_09030
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
93
|
Q9EWC6_STRGR (Q9EWC6) |
|
|
1e-23 |
117 |
31% |
|
- Product
- Cho-like protein
- Gene
-
- Organism
- Streptomyces griseus
|
1uniprot[Pubmed] 11782498 [Medline] 21642576 The candicidin gene cluster from Streptomyces griseus IMRU 3570.(Microbiology) [2002] |
|
94
|
O30483_STRHY (O30483) |
|
|
7e-23 |
114 |
29% |
|
- Product
- Putative regulatory protein
- Gene
-
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 9426000 [Medline] 98085969 A second type-I PKS gene cluster isolated from Streptomyces hygroscopicus ATCC 29253, a rapamycin-producing strain.(Gene) [1997] |
|
95
|
D5SK51_STRCL (D5SK51) |
|
|
8e-23 |
114 |
36% |
|
- Product
- Transcriptional regulatory protein
- Gene
- SCLAV_p0808
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
97
|
Q9XAN4_STRCO (Q9XAN4) |
|
|
1e-22 |
114 |
29% |
|
- Product
- Putative regulatory protein
- Gene
- SCO6696
- Organism
- Streptomyces coelicolor
|
1uniprot[Pubmed] 12000953 [Medline] 21996410 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002] |
|