| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
Q9L4W8_9ACTO (Q9L4W8) |
|
|
0.0 |
798 |
100% |
|
- Product
- NysN
- Gene
- nysN
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
2
|
Q93NX1_9ACTO (Q93NX1) |
|
|
0.0 |
658 |
84% |
|
- Product
- AmphN
- Gene
- amphN
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|
3
|
D2CKL9_PSEAH (D2CKL9) |
|
|
1e-174 |
615 |
80% |
|
- Product
- CppN
- Gene
- cppN
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 19697072 Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009] |
|
4
|
F1CLB6_9ACTO (F1CLB6) |
|
|
1e-153 |
544 |
70% |
|
- Product
- ScnG
- Gene
- scnG
- Organism
- Streptomyces chattanoogensis
|
1uniprot[Pubmed] 21330439 The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011] |
|
5
|
Q9EW94_9ACTO (Q9EW94) |
|
|
1e-150 |
535 |
68% |
|
- Product
- PimG protein
- Gene
- pimG
- Organism
- Streptomyces natalensis
|
1uniprot[Pubmed] 11094342 [Medline] 20547809 A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000] |
|
6
|
Q9EWC4_STRGR (Q9EWC4) |
|
|
1e-149 |
534 |
70% |
|
- Product
- Cytochrome P-450
- Gene
- canC
- Organism
- Streptomyces griseus
|
1uniprot[Pubmed] 11782498 [Medline] 21642576 The candicidin gene cluster from Streptomyces griseus IMRU 3570.(Microbiology) [2002] |
|
7
|
Q6W5Q7_9ACTO (Q6W5Q7) |
|
|
1e-149 |
534 |
70% |
|
- Product
- FscP
- Gene
- fscP
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
9
|
Q6T2C1_STRDI (Q6T2C1) |
|
|
1e-149 |
532 |
68% |
|
- Product
- RimG
- Gene
- rimG
- Organism
- Streptomyces diastaticus
|
1uniprot[Pubmed] 15123265 Starter unit choice determines the production of two tetraene macrolides, rimocidin and CE-108, in Streptomyces diastaticus var. 108.(Chem. Biol.) [2004] |
|
10
|
D7C2C0_STRBB (D7C2C0) |
|
|
1e-146 |
524 |
68% |
|
- Product
- Cytochrome P450
- Gene
- cyp11
SBI_00653
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
12
|
D8I293_AMYMU (D8I293) |
|
|
3e-96 |
356 |
50% |
|
- Product
- Cytochrome P450
- Gene
- AMED_0875
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
13
|
Q5ENH9_PSEAH (Q5ENH9) |
|
|
2e-94 |
350 |
50% |
|
- Product
- FadC
- Gene
- fadC
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 15752735 A gene cluster for the fatty acid catabolism from Pseudonocardia autotrophica BCRC12444.(Biochem. Biophys. Res. Commun.) [2005] |
|
15
|
Q8KRU0_PSEAH (Q8KRU0) |
|
|
4e-93 |
346 |
49% |
|
- Product
- PauC
- Gene
- pauC
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot Molecular cloning and analysis of the gene for P-450 hydroxylase from Pseudonocardia autotrophica IFO12743.(J. Microbiol.) [2002] |
|
16
|
D3PYH2_STANL (D3PYH2) |
|
|
9e-93 |
345 |
48% |
|
- Product
- Cytochrome P450
- Gene
- Snas_1843
- Organism
- Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
|
1uniprot Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009] |
|
18
|
Q156A0_AMYOR (Q156A0) |
|
|
5e-92 |
342 |
47% |
|
- Product
- Epothilone b hydroxylase
- Gene
- ebh
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 16972046 Cloning and expression of a cytochrome P450 hydroxylase gene from Amycolatopsis orientalis: hydroxylation of epothilone B for the production of epothilone F.(J. Ind. Microbiol. Biotechnol.) [2007] |
|
20
|
D8I294_AMYMU (D8I294) |
|
|
5e-92 |
342 |
50% |
|
- Product
- Cytochrome P450
- Gene
- AMED_0876
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
21
|
D2B913_STRRD (D2B913) |
|
|
7e-92 |
342 |
46% |
|
- Product
- Putative cytochrome P450
- Gene
- Sros_7070
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
24
|
D0U2E9_STRPT (D0U2E9) |
|
|
2e-90 |
337 |
47% |
|
- Product
- Hydroxylase
- Gene
-
- Organism
- Streptomyces platensis subsp. rosaceus
|
1uniprot[Pubmed] 19726666 iso-Migrastatin, migrastatin, and dorrigocin production in Streptomyces platensis NRRL 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase.(J. Biol. Chem.) [2009] |
|
25
|
C7MXK5_SACVD (C7MXK5) |
|
|
2e-89 |
334 |
48% |
|
- Product
- Cytochrome P450
- Gene
- Svir_22760
- Organism
- Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
|
1uniprot Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009] |
|
31
|
A4FF79_SACEN (A4FF79) |
|
|
3e-87 |
327 |
49% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- cyp28
SACE_3429
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
32
|
Q2L6S8_9ACTO (Q2L6S8) |
|
|
8e-87 |
325 |
49% |
|
- Product
- Cytochrome P450 type compactin 3'',4''-hydroxylase
- Gene
- moxA
- Organism
- Nonomuraea recticatena
|
1uniprot[Pubmed] 16428858 Hydroxylation of testosterone by bacterial cytochromes P450 using the Escherichia coli expression system.(Biosci. Biotechnol. Biochem.) [2006] | 2uniprot[Pubmed] 17679139 Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105).(Biochem. Biophys. Res. Commun.) [2007] | [pubmed all]
|
33
|
D8I768_AMYMU (D8I768) |
|
|
1e-86 |
324 |
47% |
|
- Product
- Cytochrome P450
- Gene
- AMED_3473
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
38
|
D2B704_STRRD (D2B704) |
|
|
2e-85 |
320 |
46% |
|
- Product
- Putative cytochrome P450
- Gene
- Sros_4934
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
40
|
Q595R1_9ACTO (Q595R1) |
|
|
4e-85 |
320 |
45% |
|
- Product
- Cytochrome P450 monooxygenase CYP105S1
- Gene
- cyp230
- Organism
- Streptomyces tubercidicus
|
1uniprot[Pubmed] 16269732 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005] | 2uniprot[Pubmed] 16269733 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005] | [pubmed all]
|
41
|
CPXF_STRGO (P18327) |
|
|
6e-85 |
319 |
47% |
|
- Product
- Cytochrome P450-SU2
CYP105B1 Cytochrome P450-CVB1
- Gene
- CYP105B1
subC
- Organism
- Streptomyces griseolus
|
1uniprot[Pubmed] 2345149 [Medline] 90264332 Genes for two herbicide-inducible cytochromes P-450 from Streptomyces griseolus.(J. Bacteriol.) [1990] |
|
44
|
Q595S4_9ACTO (Q595S4) |
|
|
1e-84 |
318 |
47% |
|
- Product
- Cytochrome P450 monooxygenase CYP105D8
- Gene
- cyp233
- Organism
- Streptomyces tubercidicus
|
1uniprot[Pubmed] 16269732 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005] | 2uniprot[Pubmed] 16269733 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005] | [pubmed all]
|
46
|
C6WQG7_ACTMD (C6WQG7) |
|
|
2e-84 |
317 |
45% |
|
- Product
- Cytochrome P450
- Gene
- Amir_2894
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
48
|
A4FDJ6_SACEN (A4FDJ6) |
|
|
4e-84 |
316 |
46% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- cyp7
SACE_2842
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
49
|
D2AYJ7_STRRD (D2AYJ7) |
|
|
7e-84 |
315 |
45% |
|
- Product
- Putative cytochrome P450
- Gene
- Sros_6255
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
52
|
Q73Z21_MYCPA (Q73Z21) |
|
|
6e-83 |
312 |
45% |
|
- Product
- Putative uncharacterized protein
- Gene
- MAP_1782c
- Organism
- Mycobacterium paratuberculosis
|
1uniprot[Pubmed] 16116077 The complete genome sequence of Mycobacterium avium subspecies paratuberculosis.(Proc. Natl. Acad. Sci. U.S.A.) [2005] |
|
58
|
Q825I8_STRAW (Q825I8) |
|
|
1e-82 |
311 |
47% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- cyp28
SAV7469 SAV_7469
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
60
|
Q9EWS4_STRCO (Q9EWS4) |
|
|
2e-82 |
310 |
45% |
|
- Product
- Putative cytochrome P450
- Gene
- SCO0774
- Organism
- Streptomyces coelicolor
|
1uniprot[Pubmed] 12000953 [Medline] 21996410 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002] |
|
61
|
C0JWI1_9BACT (C0JWI1) |
|
|
3e-82 |
310 |
73% |
|
- Product
- Candicidin biosynthesis protein FscP
- Gene
- fscP
- Organism
- uncultured bacterium
|
1uniprot Candicidin-producing Streptomyces sp. support leaf-cutting ants to protect their fungus garden against the pathogenic fungus Escovopsis.(Proc. Natl. Acad. Sci. U.S.A.) [2009] |
|
62
|
O85697_STRLI (O85697) |
|
|
3e-82 |
310 |
45% |
|
- Product
- Putative cytochrome P450 oxidoreductase
- Gene
-
- Organism
- Streptomyces lividans
|
1uniprot[Pubmed] 10627032 [Medline] 20090458 AUD4, a new amplifiable element from Streptomyces lividans.(Microbiology) [1999] |
|
66
|
E4N5M4_KITSK (E4N5M4) |
|
|
5e-82 |
309 |
46% |
|
- Product
- Putative cytochrome P450
- Gene
- KSE_06650
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
71
|
Q8KNC8_MICEC (Q8KNC8) |
|
|
1e-81 |
308 |
46% |
|
- Product
- CalE10
- Gene
- calE10
- Organism
- Micromonospora echinospora
Micromonospora purpurea
|
1uniprot[Pubmed] 12183629 [Medline] 22171414 The calicheamicin gene cluster and its iterative type I enediyne PKS.(Science) [2002] |
|
78
|
CPXE_STRGO (P18326) |
|
|
1e-80 |
305 |
45% |
|
- Product
- Cytochrome P450-SU1
CYP105A1 Cytochrome P450-CVA1
- Gene
- CYP105A1
suaC
- Organism
- Streptomyces griseolus
|
1uniprot[Pubmed] 2345149 [Medline] 90264332 Genes for two herbicide-inducible cytochromes P-450 from Streptomyces griseolus.(J. Bacteriol.) [1990] |
|
79
|
C6W8T3_ACTMD (C6W8T3) |
|
|
1e-80 |
305 |
43% |
|
- Product
- Cytochrome P450
- Gene
- Amir_3276
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
82
|
B3XWK3_9ACTO (B3XWK3) |
|
|
2e-80 |
304 |
45% |
|
- Product
- Cytochrome P450 monooxygenase
- Gene
- psmA
- Organism
- Streptomyces sp. A-1544
|
1uniprot[Pubmed] 18640605 Increase in pladienolide D production rate using a Streptomyces strain overexpressing a cytochrome P450 gene.(J. Biosci. Bioeng.) [2008] |
|
83
|
D7B189_NOCDD (D7B189) |
|
|
2e-80 |
304 |
46% |
|
- Product
- Cytochrome P450
- Gene
- Ndas_1037
- Organism
- Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
|
1uniprot Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010] |
|
86
|
B2HG54_MYCMM (B2HG54) |
|
|
4e-80 |
303 |
46% |
|
- Product
- Cytochrome P450 105Q4 Cyp105Q4
- Gene
- cyp105Q4
MMAR_4762
- Organism
- Mycobacterium marinum (strain ATCC BAA-535 / M)
|
1uniprot[Pubmed] 18403782 Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.(Genome Res.) [2008] |
|
91
|
Q595R4_9ACTO (Q595R4) |
|
|
2e-79 |
301 |
47% |
|
- Product
- Cytochrome P450 monooxygenase CYP105B2
- Gene
- cyp229
- Organism
- Streptomyces tubercidicus
|
1uniprot[Pubmed] 16269732 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005] | 2uniprot[Pubmed] 16269733 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005] | [pubmed all]
|
92
|
C7PXP7_CATAD (C7PXP7) |
|
|
2e-79 |
301 |
44% |
|
- Product
- Cytochrome P450
- Gene
- Caci_2582
- Organism
- Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
|
1uniprot Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009] |
|
93
|
Q9X9P7_STRTE (Q9X9P7) |
|
|
2e-79 |
301 |
46% |
|
- Product
- NikF protein
- Gene
- nikF
- Organism
- Streptomyces tendae
|
1uniprot[Pubmed] 10503541 [Medline] 99430866 Molecular characterization of co-transcribed genes from Streptomyces tendae Tu901 involved in the biosynthesis of the peptidyl moiety of the peptidyl nucleoside antibiotic nikkomycin.(Mol. Gen. Genet.) [1999] |
|
94
|
A0PL40_MYCUA (A0PL40) |
|
|
2e-79 |
301 |
46% |
|
- Product
- Cytochrome P450 105Q4 Cyp105Q4
- Gene
- cyp105Q4
MUL_0333
- Organism
- Mycobacterium ulcerans (strain Agy99)
|
1uniprot[Pubmed] 17210928 Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer.(Genome Res.) [2007] |
|
97
|
D8I8M5_AMYMU (D8I8M5) |
|
|
3e-79 |
300 |
46% |
|
- Product
- Cytochrome P450
- Gene
- AMED_3577
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
98
|
Q8RNW8_9ACTO (Q8RNW8) |
|
|
4e-79 |
300 |
45% |
|
- Product
- Cytochrome P450
- Gene
-
- Organism
- Streptomyces ansochromogenes
|
1uniprot[Pubmed] 12549190 [Medline] 22437434 Cloning, Sequencing and Function of SanL, a gene involved in nikkomycin biosynthesis of Streptomyces ansochromogenes.(Wei Sheng Wu Xue Bao) [2001] |
|
99
|
A8KXU3_FRASN (A8KXU3) |
|
|
4e-79 |
300 |
46% |
|
- Product
- Cytochrome P450
- Gene
- Franean1_3475
- Organism
- Frankia sp. (strain EAN1pec)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|