BLAST table : Rifam_00220

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 O52545_AMYMD
(O52545)		 
[query] 1 - 5060 (5060)
[subject] 1 - 5060 (5060)
 0.0 9894   100% RifB rifB Amycolatopsis mediterranei
Nocardia mediterranei
2
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 1 - 5060 (5060)
[subject] 1 - 5060 (5060)
 0.0 9888   100% Rifamycin polyketide synthase rifB
AMED_0618		 Amycolatopsis mediterranei (strain U-32)
3
 O52789_AMYMD
(O52789)		 
[query] 1 - 5060 (5060)
[subject] 10 - 5069 (5069)
 0.0 9884   100% Rifamycin polyketide synthase, type 1 Amycolatopsis mediterranei
Nocardia mediterranei
4
 A8M6C7_SALAI
(A8M6C7)		 
[query] 1 - 5033 (5060)
[subject] 1 - 5206 (5255)
 0.0 6943   74% Beta-ketoacyl synthase Sare_1247 Salinispora arenicola (strain CNS-205)
5
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 1 - 5005 (5060)
[subject] 1 - 5259 (5339)
(2 hsp)		 0.0 6049   65% Polyketide synthase natB Streptomyces sp. CS
6
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 32 - 5007 (5060)
[subject] 28 - 5241 (5321)
(2 hsp)		 0.0 5134   58% Polyketide synthase natC Streptomyces sp. CS
7
 A4X8L0_SALTO
(A4X8L0)		 
[query] 28 - 5005 (5060)
[subject] 1904 - 7129 (7210)
(5 hsp)		 0.0 4372   51% Beta-ketoacyl synthase Strop_2768 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
8
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 35 - 5005 (5060)
[subject] 1882 - 7031 (7110)
(5 hsp)		 0.0 4326   52% Short-chain dehydrogenase/reductase SDR Amir_2695 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
9
 E0L044_STRVO
(E0L044)		 
[query] 35 - 5038 (5060)
[subject] 1854 - 7171 (7224)
(7 hsp)		 0.0 4278   50% Beta-ketoacyl synthase StrviDRAFT_8272 Streptomyces violaceusniger Tu 4113
10
 Q82QT4_STRAW
(Q82QT4)		 
[query] 35 - 5001 (5060)
[subject] 2552 - 7657 (7746)
(11 hsp)		 0.0 4068   50% Modular polyketide synthase pteA1
SAV419
SAV_419		 Streptomyces avermitilis
11
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 28 - 5010 (5060)
[subject] 1571 - 6748 (6831)
(6 hsp)		 0.0 4063   49% ScnS1 scnS1 Streptomyces chattanoogensis
12
 Q2PC52_STRAH
(Q2PC52)		 Jump to Rubra_00380 
[query] 1 - 4464 (5060)
[subject] 1 - 4574 (5066)
(5 hsp)		 0.0 4059   53% Putative polyketide synthase rubB Streptomyces achromogenes subsp. rubradiris
13
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 3 - 5005 (5060)
[subject] 2 - 5290 (5588)
(3 hsp)		 0.0 4056   48% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
14
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 3 - 5038 (5060)
[subject] 2 - 5051 (5099)
 0.0 4046   49% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
15
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 35 - 5045 (5060)
[subject] 5575 - 10870 (10917)
(10 hsp)		 0.0 4038   49% AmphC amphC Streptomyces nodosus
16
 E8S0C5_MICSL
(E8S0C5)		 
[query] 1 - 5005 (5060)
[subject] 1549 - 6819 (9937)
(14 hsp)		 0.0 4037   49% Beta-ketoacyl synthase ML5_5898 Micromonospora sp. (strain L5)
17
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 35 - 5007 (5060)
[subject] 5254 - 10146 (10223)
(6 hsp)		 0.0 4036   49% Polyketide synthase rapB Streptomyces hygroscopicus
18
 D9T6W4_MICAI
(D9T6W4)		 
[query] 1 - 5005 (5060)
[subject] 1549 - 6819 (9936)
(14 hsp)		 0.0 4034   49% Beta-ketoacyl synthase Micau_2464 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
19
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 1 - 5037 (5060)
[subject] 1 - 5131 (5176)
 0.0 4031   49% ObsB Saccharopolyspora spinosa
20
 B4VDY6_9ACTO
(B4VDY6)		 
[query] 35 - 4612 (5060)
[subject] 19 - 4843 (4894)
(3 hsp)		 0.0 4029   51% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
21
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 32 - 5033 (5060)
[subject] 989 - 5996 (6078)
(6 hsp)		 0.0 4023   49% ObsA Saccharopolyspora spinosa
22
 D7BRD4_STRBB
(D7BRD4)		 
[query] 42 - 5042 (5060)
[subject] 4605 - 9902 (9950)
(10 hsp)		 0.0 4020   49% Short-chain dehydrogenase/reductase SDR SBI_01976 Streptomyces bingchenggensis (strain BCW-1)
23
 Q52V52_9ACTO
(Q52V52)		 
[query] 5 - 5042 (5060)
[subject] 4 - 5381 (5432)
 0.0 3982   48% Polyketide synthase type I Streptomyces aizunensis
24
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 28 - 5010 (5060)
[subject] 1555 - 6714 (6797)
(7 hsp)		 0.0 3981   49% PimS1 protein
Polyketide synthase		 pimS1 Streptomyces natalensis
25
 D1XUK5_9ACTO
(D1XUK5)		 
[query] 5 - 5033 (5060)
[subject] 4 - 5097 (5157)
 0.0 3925   49% Short-chain dehydrogenase/reductase SDR SACTEDRAFT_6365 Streptomyces sp. SA3_actE
26
 E8WEN5_STRFA
(E8WEN5)		 
[query] 5 - 5033 (5060)
[subject] 4 - 5096 (5156)
 0.0 3878   48% Beta-ketoacyl synthase Sfla_0979 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
27
 D9VEY7_9ACTO
(D9VEY7)		 
[query] 23 - 5007 (5060)
[subject] 112 - 5217 (5260)
(5 hsp)		 0.0 3868   47% Modular polyketide synthase SSMG_05939 Streptomyces sp. AA4
28
 Q9S0R4_STRAW
(Q9S0R4)		 Jump to Aver_00080 
[query] 1 - 5009 (5060)
[subject] 1 - 5442 (5532)
(3 hsp)		 0.0 3856   47% Type I polyketide synthase AVES 3 aveA3
SAV942
SAV_942		 Streptomyces avermitilis
29
 D8HZ86_AMYMU
(D8HZ86)		 
[query] 3 - 3304 (5060)
[subject] 2 - 3409 (3413)
(3 hsp)		 0.0 3848   63% Rifamycin polyketide synthase rifE
AMED_0621		 Amycolatopsis mediterranei (strain U-32)
30
 O54593_AMYMD
(O54593)		 Jump to Rifam_00250 
[query] 3 - 3304 (5060)
[subject] 2 - 3409 (3413)
(3 hsp)		 0.0 3848   63% RifE
Rifamycin polyketide synthase, type 1		 rifE Amycolatopsis mediterranei
Nocardia mediterranei
31
 C6K7D8_9ACTO
(C6K7D8)		 
[query] 24 - 5059 (5060)
[subject] 3139 - 7905 (7938)
(6 hsp)		 0.0 3845   48% Polyketide synthase rapA Actinoplanes sp. N902-109
32
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 33 - 5034 (5060)
[subject] 1024 - 6331 (6383)
(6 hsp)		 0.0 3842   45% Polyketide synthase type I mlaA1 Streptomyces sp. MP39-85
33
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 27 - 5005 (5060)
[subject] 1780 - 6945 (10625)
(8 hsp)		 0.0 3793   49% FscC fscC Streptomyces sp. FR-008
34
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 3 - 5005 (5060)
[subject] 7 - 5110 (5400)
 0.0 3786   48% Short-chain dehydrogenase/reductase SDR Amir_2684 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
35
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 33 - 5045 (5060)
[subject] 5582 - 10825 (10876)
(7 hsp)		 0.0 3770   48% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
36
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 28 - 4643 (5060)
[subject] 3795 - 8572 (10827)
(15 hsp)		 0.0 3698   50% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
37
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 30 - 4642 (5060)
[subject] 4136 - 8782 (9528)
(12 hsp)		 0.0 3697   49% Type I modular polyketide synthase ttnA Streptomyces griseochromogenes
38
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 30 - 4642 (5060)
[subject] 4252 - 8902 (9648)
(12 hsp)		 0.0 3692   49% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
39
 Q0PCZ9_STRHA
(Q0PCZ9)		 Jump to Halsto_00060 
[query] 5 - 4213 (5060)
[subject] 4 - 4526 (5232)
(6 hsp)		 0.0 3640   50% Type I polyketide synthase hlsF Streptomyces halstedii
40
 B5L6K9_MICCH
(B5L6K9)		 
[query] 11 - 5059 (5060)
[subject] 1711 - 7004 (7007)
(2 hsp)		 0.0 3636   45% Putative type I polyketide synthase Micromonospora chalcea
41
 A8M6D0_SALAI
(A8M6D0)		 
[query] 3 - 3306 (5060)
[subject] 2 - 3483 (3494)
(2 hsp)		 0.0 3632   61% Acyl transferase Sare_1250 Salinispora arenicola (strain CNS-205)
42
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 5 - 4656 (5060)
[subject] 4 - 4513 (6260)
(9 hsp)		 0.0 3628   48% Polyketide synthase rapC Streptomyces hygroscopicus
43
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 1 - 4508 (5060)
[subject] 1 - 4698 (11096)
(14 hsp)		 0.0 3618   49% NysC nysC Streptomyces noursei
44
 E9KTB5_STRKN
(E9KTB5)		 
[query] 35 - 5006 (5060)
[subject] 1171 - 5984 (7591)
(7 hsp)		 0.0 3613   46% Polyketide synthase fkbB
Tcs_SK_031		 Streptomyces kanamyceticus
45
 Q9KIE0_STRHY
(Q9KIE0)		 Jump to Asco_00140 
[query] 35 - 5005 (5060)
[subject] 1161 - 5945 (7525)
(8 hsp)		 0.0 3583   47% FkbB fkbB Streptomyces hygroscopicus subsp. ascomyceticus
46
 F8JUL0_STRCT
(F8JUL0)		 
[query] 35 - 4322 (5060)
[subject] 1030 - 5431 (5950)
(9 hsp)		 0.0 3573   51% Putative polyketide synthase SCAT_3270 Streptomyces cattleya
47
 B3TMQ7_9ACTO
(B3TMQ7)		 
[query] 5 - 4838 (5060)
[subject] 2 - 4960 (6872)
(5 hsp)		 0.0 3563   46% Polyketide synthase KijS2 Actinomadura kijaniata
48
 F8QPG1_9ACTO
(F8QPG1)		 
[query] 1713 - 5059 (5060)
[subject] 30 - 3615 (3621)
(3 hsp)		 0.0 3538   59% Polyketide synthase natD Streptomyces sp. CS
49
 B1W5P4_STRGG
(B1W5P4)		 
[query] 14 - 5009 (5060)
[subject] 16 - 4770 (4843)
(3 hsp)		 0.0 3503   45% Putative type-I PKS pks3-2
SGR_6372		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
50
 Q9ZGA4_9ACTO
(Q9ZGA4)		 
[query] 35 - 5006 (5060)
[subject] 1183 - 5979 (7576)
(7 hsp)		 0.0 3483   46% FK506 polyketide synthase fkbB Streptomyces sp. MA6548
51
 F1D8Z6_9ACTO
(F1D8Z6)		 
[query] 35 - 5001 (5060)
[subject] 1216 - 6043 (7655)
(5 hsp)		 0.0 3481   46% FkbB Streptomyces sp. MJM7001
52
 E9KTI2_9ACTO
(E9KTI2)		 
[query] 35 - 5001 (5060)
[subject] 1207 - 6034 (7646)
(5 hsp)		 0.0 3479   46% Polyketide synthase fkbB
Tcs_11604BP_028		 Streptomyces sp. KCTC 11604BP
53
 C0Z477_STRVN
(C0Z477)		 
[query] 31 - 4203 (5060)
[subject] 1057 - 5388 (6130)
(7 hsp)		 0.0 3463   51% Type I polyketide synthase, loading module and modules 1-3 ken16 Streptomyces violaceoruber
54
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 1 - 4199 (5060)
[subject] 1 - 4269 (8301)
(5 hsp)		 0.0 3441   51% Type I polyketide synthase sfaH Streptomyces flaveolus
55
 F8QPG2_9ACTO
(F8QPG2)		 
[query] 1717 - 5010 (5060)
[subject] 35 - 3525 (3533)
(3 hsp)		 0.0 3429   58% Polyketide synthase natE Streptomyces sp. CS
56
 D7P611_CHOCO
(D7P611)		 
[query] 477 - 4642 (5060)
[subject] 985 - 5462 (6255)
(10 hsp)		 0.0 3422   48% TugA tugA Chondromyces crocatus
57
 F4F7F4_VERMA
(F4F7F4)		 
[query] 35 - 5037 (5060)
[subject] 955 - 5769 (5781)
(7 hsp)		 0.0 3415   45% Modular polyketide synthase VAB18032_16435 Verrucosispora maris (strain AB-18-032)
58
 A8LUX2_SALAI
(A8LUX2)		 
[query] 35 - 4191 (5060)
[subject] 991 - 5202 (7279)
(14 hsp)		 0.0 3393   49% Beta-ketoacyl synthase Sare_3156 Salinispora arenicola (strain CNS-205)
59
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 33 - 4322 (5060)
[subject] 1025 - 5574 (5582)
(9 hsp)		 0.0 3373   45% Polyketide synthase type I becA Streptomyces sp. DSM 21069
60
 F8JVX1_STRCT
(F8JVX1)		 
[query] 29 - 4187 (5060)
[subject] 1037 - 5399 (6125)
(11 hsp)		 0.0 3280   47% Putative 6-methylsalicylic acid synthase SCAT_0136 Streptomyces cattleya 2.3.1.165

2.3.1.94
61
 D9VBL5_9ACTO
(D9VBL5)		 
[query] 37 - 3987 (5060)
[subject] 984 - 5007 (5113)
(6 hsp)		 0.0 3273   50% Modular polyketide synthase SSMG_01148 Streptomyces sp. AA4
62
 D7F1M0_9ACTO
(D7F1M0)		 
[query] 6 - 4228 (5060)
[subject] 7 - 4432 (5136)
(5 hsp)		 0.0 3268   46% Polyketide synthase tsnAII Streptomyces longisporoflavus
63
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 1242 - 5041 (5060)
[subject] 2277 - 6200 (6241)
(8 hsp)		 0.0 3124   50% Polyketide synthase KijS1 Actinomadura kijaniata
64
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 1321 - 5005 (5060)
[subject] 3374 - 7196 (7488)
(7 hsp)		 0.0 3054   50% ObsC Saccharopolyspora spinosa
65
 Q52V50_9ACTO
(Q52V50)		 
[query] 1321 - 5042 (5060)
[subject] 3527 - 7461 (7510)
(5 hsp)		 0.0 3041   49% Polyketide synthase type I Streptomyces aizunensis
66
 E0D206_9ACTO
(E0D206)		 Jump to FD891_00050 
[query] 1717 - 5006 (5060)
[subject] 34 - 3495 (3799)
(3 hsp)		 0.0 2982   53% Polyketide synthase gfsE Streptomyces graminofaciens
67
 A8J704_9ACTO
(A8J704)		 
[query] 1339 - 5060 (5060)
[subject] 1719 - 5649 (5674)
(6 hsp)		 0.0 2969   48% Modular polyketide synthase nemA3 Streptomyces cyaneogriseus subsp. noncyanogenus
68
 Q52V53_9ACTO
(Q52V53)		 
[query] 1251 - 5037 (5060)
[subject] 1110 - 5155 (5207)
(8 hsp)		 0.0 2968   48% Polyketide synthase type I Streptomyces aizunensis
69
 D6C477_9ACTO
(D6C477)		 Jump to Meili_00310 
[query] 1344 - 5008 (5060)
[subject] 1787 - 5737 (5822)
(8 hsp)		 0.0 2959   48% Modular polyketide synthase meiA3 Streptomyces nanchangensis
70
 D7F1M1_9ACTO
(D7F1M1)		 
[query] 1339 - 5038 (5060)
[subject] 1712 - 5578 (5630)
(6 hsp)		 0.0 2958   47% Polyketide synthase tsnAIII Streptomyces longisporoflavus
71
 Q93H87_STRAW
(Q93H87)		 
[query] 1242 - 5001 (5060)
[subject] 2061 - 5959 (6048)
(11 hsp)		 0.0 2943   48% Modular polyketide synthase pteA1 Streptomyces avermitilis
72
 B4VB11_9ACTO
(B4VB11)		 
[query] 1401 - 5001 (5060)
[subject] 4 - 3838 (3928)
(4 hsp)		 0.0 2905   49% Polyketide synthase type I SSAG_04921 Streptomyces sp. Mg1
73
 Q0R4M5_STRAT
(Q0R4M5)		 Jump to Chth_00290 
[query] 1305 - 5060 (5060)
[subject] 1721 - 5716 (5718)
(6 hsp)		 0.0 2854   45% ChlA3 Streptomyces antibioticus
74
 Q82QT5_STRAW
(Q82QT5)		 
[query] 1715 - 5030 (5060)
[subject] 32 - 3498 (3564)
(3 hsp)		 0.0 2853   51% Modular polyketide synthase pteA2
SAV418
SAV_418		 Streptomyces avermitilis
75
 B5L6K8_MICCH
(B5L6K8)		 
[query] 1242 - 5041 (5060)
[subject] 2284 - 6265 (6305)
(9 hsp)		 0.0 2852   46% Putative type I polyketide synthase Micromonospora chalcea
76
 Q93H86_STRAW
(Q93H86)		 
[query] 1724 - 5030 (5060)
[subject] 1 - 3458 (3524)
(3 hsp)		 0.0 2835   51% Modular polyketide synthase pteA2 Streptomyces avermitilis
77
 Q1MX73_9ACTO
(Q1MX73)		 Jump to Tetrn_00160 
[query] 1329 - 5039 (5060)
[subject] 1718 - 5606 (5657)
(5 hsp)		 0.0 2813   46% Type I polyketide synthase tmnAIV Streptomyces sp. NRRL 11266
78
 C5HV15_STRAT
(C5HV15)		 Jump to Indano_00170 
[query] 3 - 3313 (5060)
[subject] 4 - 3512 (3596)
(2 hsp)		 0.0 2799   49% Polyketide synthase idmM Streptomyces antibioticus
79
 E0KBI0_STRVO
(E0KBI0)		 
[query] 1713 - 4667 (5060)
[subject] 33 - 3184 (3955)
(6 hsp)		 0.0 2790   53% Acyl transferase StrviDRAFT_0195 Streptomyces violaceusniger Tu 4113
80
 Q68BG4_STRHA
(Q68BG4)		 Jump to Halsto_00020 
[query] 1251 - 4643 (5060)
[subject] 1094 - 4733 (7111)
(14 hsp)		 0.0 2784   49% Type I polyketide synthase hlsB Streptomyces halstedii
81
 E8WEN9_STRFA
(E8WEN9)		 
[query] 1 - 3307 (5060)
[subject] 1 - 3423 (3511)
(2 hsp)		 0.0 2781   50% Mycocerosate synthase, 6-deoxyerythronolide-B synthase Sfla_0983 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD) 2.3.1.111

2.3.1.94
82
 Q30CS1_STRAU
(Q30CS1)		 Jump to Alip_00140 
[query] 3 - 3304 (5060)
[subject] 2 - 3503 (3582)
(3 hsp)		 0.0 2779   50% LipPks2 lipPks2 Streptomyces aureofaciens
83
 Q0R4M8_STRAT
(Q0R4M8)		 Jump to Chth_00260 
[query] 1601 - 5012 (5060)
[subject] 971 - 4618 (4699)
(6 hsp)		 0.0 2768   48% ChlA1 Streptomyces antibioticus
84
 C3VLZ7_9ACTO
(C3VLZ7)		 
[query] 35 - 3304 (5060)
[subject] 37 - 3291 (3373)
(2 hsp)		 0.0 2748   50% Polyketide synthase type I mlaF Streptomyces sp. MP39-85
85
 E0D205_9ACTO
(E0D205)		 Jump to FD891_00040 
[query] 1717 - 5010 (5060)
[subject] 34 - 3547 (3639)
(2 hsp)		 0.0 2744   49% Polyketide synthase gfsD Streptomyces graminofaciens
86
 C3VLW9_9ACTO
(C3VLW9)		 
[query] 5 - 3304 (5060)
[subject] 7 - 3294 (3377)
(3 hsp)		 0.0 2742   50% Polyketide synthase type I becF Streptomyces sp. DSM 21069
87
 D7CC08_STRBB
(D7CC08)		 
[query] 1717 - 4670 (5060)
[subject] 34 - 3200 (5530)
(10 hsp)		 0.0 2741   53% Putative type I polyketide synthase pks5-2
SBI_01382		 Streptomyces bingchenggensis (strain BCW-1)
88
 D6B4Q9_9ACTO
(D6B4Q9)		 
[query] 1248 - 5050 (5060)
[subject] 103 - 4054 (5945)
(7 hsp)		 0.0 2734   48% Polyketide synthase SSHG_00090 Streptomyces albus J1074
89
 Q76KY0_STRHA
(Q76KY0)		 Jump to Vicen_00200 
[query] 35 - 3304 (5060)
[subject] 2220 - 5744 (5826)
(10 hsp)		 0.0 2714   49% Polyketide synthase modules 1-3 vinP1 Streptomyces halstedii
90
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 1220 - 4213 (5060)
[subject] 1328 - 4501 (5214)
(9 hsp)		 0.0 2712   54% Polyketide synthase idmN Streptomyces antibioticus
91
 C3VLY6_9ACTO
(C3VLY6)		 
[query] 1654 - 5001 (5060)
[subject] 46 - 3479 (3530)
(2 hsp)		 0.0 2711   49% Polyketide synthase type I mlaB Streptomyces sp. MP39-85
92
 C9YYI2_STRSW
(C9YYI2)		 
[query] 1717 - 4670 (5060)
[subject] 38 - 3171 (3919)
(6 hsp)		 0.0 2707   53% Putative type I polyketide synthase SCAB_83911 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
93
 D7C2B8_STRBB
(D7C2B8)		 
[query] 1321 - 4652 (5060)
[subject] 3239 - 6735 (7498)
(15 hsp)		 0.0 2706   49% Type I modular polyketide synthase pks3-2
SBI_00651		 Streptomyces bingchenggensis (strain BCW-1)
94
 C3VLV8_9ACTO
(C3VLV8)		 
[query] 1618 - 5001 (5060)
[subject] 3 - 3480 (3527)
(2 hsp)		 0.0 2705   49% Polyketide synthase type I becB Streptomyces sp. DSM 21069
95
 D7CC07_STRBB
(D7CC07)		 
[query] 1605 - 4670 (5060)
[subject] 938 - 4223 (4979)
(9 hsp)		 0.0 2692   51% Putative type I polyketide synthase pks5-1
SBI_01381		 Streptomyces bingchenggensis (strain BCW-1)
96
 Q30CS0_STRAU
(Q30CS0)		 Jump to Alip_00150 
[query] 1717 - 5057 (5060)
[subject] 34 - 3607 (3612)
(3 hsp)		 0.0 2687   48% LipPks3 lipPks3 Streptomyces aureofaciens
97
 Q52V49_9ACTO
(Q52V49)		 
[query] 1717 - 5005 (5060)
[subject] 33 - 3577 (3872)
(4 hsp)		 0.0 2683   49% Polyketide synthase type I Streptomyces aizunensis
98
 Q54297_STRHY
(Q54297)		 Jump to Rapam_00120 
[query] 1321 - 4650 (5060)
[subject] 2905 - 6161 (8563)
(13 hsp)		 0.0 2674   50% Polyketide synthase rapA Streptomyces hygroscopicus
99
 D9T6W9_MICAI
(D9T6W9)		 
[query] 1717 - 5008 (5060)
[subject] 34 - 3571 (3649)
(4 hsp)		 0.0 2669   49% Acyl transferase Micau_2469 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
100
 B1W4J1_STRGG
(B1W4J1)		 
[query] 1600 - 5005 (5060)
[subject] 938 - 4585 (4681)
(8 hsp)		 0.0 2667   48% Putative type-I PKS pks2-1
SGR_6179		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 O52545_AMYMD
(O52545)		 
[query] 1 - 5060 (5060)
[subject] 1 - 5060 (5060)
 0.0 9894   100%
Product
RifB
Gene
rifB
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
2
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 1 - 5060 (5060)
[subject] 1 - 5060 (5060)
 0.0 9888   100%
Product
Rifamycin polyketide synthase
Gene
rifB
AMED_0618
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
5
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 1 - 5005 (5060)
[subject] 1 - 5259 (5339)
(2 hsp)		 0.0 6049   65%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
6
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 32 - 5007 (5060)
[subject] 28 - 5241 (5321)
(2 hsp)		 0.0 5134   58%
Product
Polyketide synthase
Gene
natC
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
8
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 35 - 5005 (5060)
[subject] 1882 - 7031 (7110)
(5 hsp)		 0.0 4326   52%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2695
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
10
 Q82QT4_STRAW
(Q82QT4)		 
[query] 35 - 5001 (5060)
[subject] 2552 - 7657 (7746)
(11 hsp)		 0.0 4068   50%
Product
Modular polyketide synthase
Gene
pteA1
SAV419
SAV_419
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
11
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 28 - 5010 (5060)
[subject] 1571 - 6748 (6831)
(6 hsp)		 0.0 4063   49%
Product
ScnS1
Gene
scnS1
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
12
 Q2PC52_STRAH
(Q2PC52)		 Jump to Rubra_00380 
[query] 1 - 4464 (5060)
[subject] 1 - 4574 (5066)
(5 hsp)		 0.0 4059   53%
Product
Putative polyketide synthase
Gene
rubB
Organism
Streptomyces achromogenes subsp. rubradiris
1uniprot[Pubmed] 9387157 [Medline] 98048398
Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997]
2uniprot[Pubmed] 12889805 [Medline] 22771458
Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003]
[pubmed all]
13
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 3 - 5005 (5060)
[subject] 2 - 5290 (5588)
(3 hsp)		 0.0 4056   48%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
14
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 3 - 5038 (5060)
[subject] 2 - 5051 (5099)
 0.0 4046   49%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
15
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 35 - 5045 (5060)
[subject] 5575 - 10870 (10917)
(10 hsp)		 0.0 4038   49%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
17
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 35 - 5007 (5060)
[subject] 5254 - 10146 (10223)
(6 hsp)		 0.0 4036   49%
Product
Polyketide synthase
Gene
rapB
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
19
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 1 - 5037 (5060)
[subject] 1 - 5131 (5176)
 0.0 4031   49%
Product
ObsB
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
21
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 32 - 5033 (5060)
[subject] 989 - 5996 (6078)
(6 hsp)		 0.0 4023   49%
Product
ObsA
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
22
 D7BRD4_STRBB
(D7BRD4)		 
[query] 42 - 5042 (5060)
[subject] 4605 - 9902 (9950)
(10 hsp)		 0.0 4020   49%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_01976
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
23
 Q52V52_9ACTO
(Q52V52)		 
[query] 5 - 5042 (5060)
[subject] 4 - 5381 (5432)
 0.0 3982   48%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
24
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 28 - 5010 (5060)
[subject] 1555 - 6714 (6797)
(7 hsp)		 0.0 3981   49%
Product
PimS1 protein
Polyketide synthase
Gene
pimS1
Organism
Streptomyces natalensis
1uniprot[Pubmed] 10187796 [Medline] 99214571
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999]
2uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
[pubmed all]
28
 Q9S0R4_STRAW
(Q9S0R4)		 Jump to Aver_00080 
[query] 1 - 5009 (5060)
[subject] 1 - 5442 (5532)
(3 hsp)		 0.0 3856   47%
Product
Type I polyketide synthase AVES 3
Gene
aveA3
SAV942
SAV_942
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 10449723 [Medline] 99380548
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999]
2uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
3uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
29
 D8HZ86_AMYMU
(D8HZ86)		 
[query] 3 - 3304 (5060)
[subject] 2 - 3409 (3413)
(3 hsp)		 0.0 3848   63%
Product
Rifamycin polyketide synthase
Gene
rifE
AMED_0621
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
30
 O54593_AMYMD
(O54593)		 Jump to Rifam_00250 
[query] 3 - 3304 (5060)
[subject] 2 - 3409 (3413)
(3 hsp)		 0.0 3848   63%
Product
RifE
Rifamycin polyketide synthase, type 1
Gene
rifE
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
32
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 33 - 5034 (5060)
[subject] 1024 - 6331 (6383)
(6 hsp)		 0.0 3842   45%
Product
Polyketide synthase type I
Gene
mlaA1
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
33
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 27 - 5005 (5060)
[subject] 1780 - 6945 (10625)
(8 hsp)		 0.0 3793   49%
Product
FscC
Gene
fscC
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
34
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 3 - 5005 (5060)
[subject] 7 - 5110 (5400)
 0.0 3786   48%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2684
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
35
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 33 - 5045 (5060)
[subject] 5582 - 10825 (10876)
(7 hsp)		 0.0 3770   48%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
36
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 28 - 4643 (5060)
[subject] 3795 - 8572 (10827)
(15 hsp)		 0.0 3698   50%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
37
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 30 - 4642 (5060)
[subject] 4136 - 8782 (9528)
(12 hsp)		 0.0 3697   49%
Product
Type I modular polyketide synthase
Gene
ttnA
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
38
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 30 - 4642 (5060)
[subject] 4252 - 8902 (9648)
(12 hsp)		 0.0 3692   49%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
40
 B5L6K9_MICCH
(B5L6K9)		 
[query] 11 - 5059 (5060)
[subject] 1711 - 7004 (7007)
(2 hsp)		 0.0 3636   45%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
42
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 5 - 4656 (5060)
[subject] 4 - 4513 (6260)
(9 hsp)		 0.0 3628   48%
Product
Polyketide synthase
Gene
rapC
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
43
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 1 - 4508 (5060)
[subject] 1 - 4698 (11096)
(14 hsp)		 0.0 3618   49%
Product
NysC
Gene
nysC
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
44
 E9KTB5_STRKN
(E9KTB5)		 
[query] 35 - 5006 (5060)
[subject] 1171 - 5984 (7591)
(7 hsp)		 0.0 3613   46%
Product
Polyketide synthase
Gene
fkbB
Tcs_SK_031
Organism
Streptomyces kanamyceticus
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
45
 Q9KIE0_STRHY
(Q9KIE0)		 Jump to Asco_00140 
[query] 35 - 5005 (5060)
[subject] 1161 - 5945 (7525)
(8 hsp)		 0.0 3583   47%
Product
FkbB
Gene
fkbB
Organism
Streptomyces hygroscopicus subsp. ascomyceticus
1uniprot[Pubmed] 10863099 [Medline] 20323220
The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.(Gene) [2000]
47
 B3TMQ7_9ACTO
(B3TMQ7)		 
[query] 5 - 4838 (5060)
[subject] 2 - 4960 (6872)
(5 hsp)		 0.0 3563   46%
Product
Polyketide synthase
Gene
KijS2
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
48
 F8QPG1_9ACTO
(F8QPG1)		 
[query] 1713 - 5059 (5060)
[subject] 30 - 3615 (3621)
(3 hsp)		 0.0 3538   59%
Product
Polyketide synthase
Gene
natD
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
49
 B1W5P4_STRGG
(B1W5P4)		 
[query] 14 - 5009 (5060)
[subject] 16 - 4770 (4843)
(3 hsp)		 0.0 3503   45%
Product
Putative type-I PKS
Gene
pks3-2
SGR_6372
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
50
 Q9ZGA4_9ACTO
(Q9ZGA4)		 
[query] 35 - 5006 (5060)
[subject] 1183 - 5979 (7576)
(7 hsp)		 0.0 3483   46%
Product
FK506 polyketide synthase
Gene
fkbB
Organism
Streptomyces sp. MA6548
1uniprot[Pubmed] 9780228 [Medline] 98451508
The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506.(Eur. J. Biochem.) [1998]
52
 E9KTI2_9ACTO
(E9KTI2)		 
[query] 35 - 5001 (5060)
[subject] 1207 - 6034 (7646)
(5 hsp)		 0.0 3479   46%
Product
Polyketide synthase
Gene
fkbB
Tcs_11604BP_028
Organism
Streptomyces sp. KCTC 11604BP
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
54
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 1 - 4199 (5060)
[subject] 1 - 4269 (8301)
(5 hsp)		 0.0 3441   51%
Product
Type I polyketide synthase
Gene
sfaH
Organism
Streptomyces flaveolus
1uniprot
Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010]
55
 F8QPG2_9ACTO
(F8QPG2)		 
[query] 1717 - 5010 (5060)
[subject] 35 - 3525 (3533)
(3 hsp)		 0.0 3429   58%
Product
Polyketide synthase
Gene
natE
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
56
 D7P611_CHOCO
(D7P611)		 
[query] 477 - 4642 (5060)
[subject] 985 - 5462 (6255)
(10 hsp)		 0.0 3422   48%
Product
TugA
Gene
tugA
Organism
Chondromyces crocatus
1uniprot[Pubmed] 20416506
Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010]
57
 F4F7F4_VERMA
(F4F7F4)		 
[query] 35 - 5037 (5060)
[subject] 955 - 5769 (5781)
(7 hsp)		 0.0 3415   45%
Product
Modular polyketide synthase
Gene
VAB18032_16435
Organism
Verrucosispora maris (strain AB-18-032)
1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]
59
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 33 - 4322 (5060)
[subject] 1025 - 5574 (5582)
(9 hsp)		 0.0 3373   45%
Product
Polyketide synthase type I
Gene
becA
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
63
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 1242 - 5041 (5060)
[subject] 2277 - 6200 (6241)
(8 hsp)		 0.0 3124   50%
Product
Polyketide synthase
Gene
KijS1
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
64
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 1321 - 5005 (5060)
[subject] 3374 - 7196 (7488)
(7 hsp)		 0.0 3054   50%
Product
ObsC
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
65
 Q52V50_9ACTO
(Q52V50)		 
[query] 1321 - 5042 (5060)
[subject] 3527 - 7461 (7510)
(5 hsp)		 0.0 3041   49%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
66
 E0D206_9ACTO
(E0D206)		 Jump to FD891_00050 
[query] 1717 - 5006 (5060)
[subject] 34 - 3495 (3799)
(3 hsp)		 0.0 2982   53%
Product
Polyketide synthase
Gene
gfsE
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
68
 Q52V53_9ACTO
(Q52V53)		 
[query] 1251 - 5037 (5060)
[subject] 1110 - 5155 (5207)
(8 hsp)		 0.0 2968   48%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
69
 D6C477_9ACTO
(D6C477)		 Jump to Meili_00310 
[query] 1344 - 5008 (5060)
[subject] 1787 - 5737 (5822)
(8 hsp)		 0.0 2959   48%
Product
Modular polyketide synthase
Gene
meiA3
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
71
 Q93H87_STRAW
(Q93H87)		 
[query] 1242 - 5001 (5060)
[subject] 2061 - 5959 (6048)
(11 hsp)		 0.0 2943   48%
Product
Modular polyketide synthase
Gene
pteA1
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
73
 Q0R4M5_STRAT
(Q0R4M5)		 Jump to Chth_00290 
[query] 1305 - 5060 (5060)
[subject] 1721 - 5716 (5718)
(6 hsp)		 0.0 2854   45%
Product
ChlA3
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
74
 Q82QT5_STRAW
(Q82QT5)		 
[query] 1715 - 5030 (5060)
[subject] 32 - 3498 (3564)
(3 hsp)		 0.0 2853   51%
Product
Modular polyketide synthase
Gene
pteA2
SAV418
SAV_418
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
75
 B5L6K8_MICCH
(B5L6K8)		 
[query] 1242 - 5041 (5060)
[subject] 2284 - 6265 (6305)
(9 hsp)		 0.0 2852   46%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
76
 Q93H86_STRAW
(Q93H86)		 
[query] 1724 - 5030 (5060)
[subject] 1 - 3458 (3524)
(3 hsp)		 0.0 2835   51%
Product
Modular polyketide synthase
Gene
pteA2
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
78
 C5HV15_STRAT
(C5HV15)		 Jump to Indano_00170 
[query] 3 - 3313 (5060)
[subject] 4 - 3512 (3596)
(2 hsp)		 0.0 2799   49%
Product
Polyketide synthase
Gene
idmM
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
80
 Q68BG4_STRHA
(Q68BG4)		 Jump to Halsto_00020 
[query] 1251 - 4643 (5060)
[subject] 1094 - 4733 (7111)
(14 hsp)		 0.0 2784   49%
Product
Type I polyketide synthase
Gene
hlsB
Organism
Streptomyces halstedii
1uniprot
Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004]
82
 Q30CS1_STRAU
(Q30CS1)		 Jump to Alip_00140 
[query] 3 - 3304 (5060)
[subject] 2 - 3503 (3582)
(3 hsp)		 0.0 2779   50%
Product
LipPks2
Gene
lipPks2
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 16723573
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006]
83
 Q0R4M8_STRAT
(Q0R4M8)		 Jump to Chth_00260 
[query] 1601 - 5012 (5060)
[subject] 971 - 4618 (4699)
(6 hsp)		 0.0 2768   48%
Product
ChlA1
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
84
 C3VLZ7_9ACTO
(C3VLZ7)		 
[query] 35 - 3304 (5060)
[subject] 37 - 3291 (3373)
(2 hsp)		 0.0 2748   50%
Product
Polyketide synthase type I
Gene
mlaF
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
85
 E0D205_9ACTO
(E0D205)		 Jump to FD891_00040 
[query] 1717 - 5010 (5060)
[subject] 34 - 3547 (3639)
(2 hsp)		 0.0 2744   49%
Product
Polyketide synthase
Gene
gfsD
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
86
 C3VLW9_9ACTO
(C3VLW9)		 
[query] 5 - 3304 (5060)
[subject] 7 - 3294 (3377)
(3 hsp)		 0.0 2742   50%
Product
Polyketide synthase type I
Gene
becF
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
87
 D7CC08_STRBB
(D7CC08)		 
[query] 1717 - 4670 (5060)
[subject] 34 - 3200 (5530)
(10 hsp)		 0.0 2741   53%
Product
Putative type I polyketide synthase
Gene
pks5-2
SBI_01382
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
89
 Q76KY0_STRHA
(Q76KY0)		 Jump to Vicen_00200 
[query] 35 - 3304 (5060)
[subject] 2220 - 5744 (5826)
(10 hsp)		 0.0 2714   49%
Product
Polyketide synthase modules 1-3
Gene
vinP1
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
90
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 1220 - 4213 (5060)
[subject] 1328 - 4501 (5214)
(9 hsp)		 0.0 2712   54%
Product
Polyketide synthase
Gene
idmN
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
91
 C3VLY6_9ACTO
(C3VLY6)		 
[query] 1654 - 5001 (5060)
[subject] 46 - 3479 (3530)
(2 hsp)		 0.0 2711   49%
Product
Polyketide synthase type I
Gene
mlaB
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
92
 C9YYI2_STRSW
(C9YYI2)		 
[query] 1717 - 4670 (5060)
[subject] 38 - 3171 (3919)
(6 hsp)		 0.0 2707   53%
Product
Putative type I polyketide synthase
Gene
SCAB_83911
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
93
 D7C2B8_STRBB
(D7C2B8)		 
[query] 1321 - 4652 (5060)
[subject] 3239 - 6735 (7498)
(15 hsp)		 0.0 2706   49%
Product
Type I modular polyketide synthase
Gene
pks3-2
SBI_00651
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
94
 C3VLV8_9ACTO
(C3VLV8)		 
[query] 1618 - 5001 (5060)
[subject] 3 - 3480 (3527)
(2 hsp)		 0.0 2705   49%
Product
Polyketide synthase type I
Gene
becB
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
95
 D7CC07_STRBB
(D7CC07)		 
[query] 1605 - 4670 (5060)
[subject] 938 - 4223 (4979)
(9 hsp)		 0.0 2692   51%
Product
Putative type I polyketide synthase
Gene
pks5-1
SBI_01381
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
96
 Q30CS0_STRAU
(Q30CS0)		 Jump to Alip_00150 
[query] 1717 - 5057 (5060)
[subject] 34 - 3607 (3612)
(3 hsp)		 0.0 2687   48%
Product
LipPks3
Gene
lipPks3
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 16723573
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006]
97
 Q52V49_9ACTO
(Q52V49)		 
[query] 1717 - 5005 (5060)
[subject] 33 - 3577 (3872)
(4 hsp)		 0.0 2683   49%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
98
 Q54297_STRHY
(Q54297)		 Jump to Rapam_00120 
[query] 1321 - 4650 (5060)
[subject] 2905 - 6161 (8563)
(13 hsp)		 0.0 2674   50%
Product
Polyketide synthase
Gene
rapA
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
100
 B1W4J1_STRGG
(B1W4J1)		 
[query] 1600 - 5005 (5060)
[subject] 938 - 4585 (4681)
(8 hsp)		 0.0 2667   48%
Product
Putative type-I PKS
Gene
pks2-1
SGR_6179
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]