| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
Q54823_STRPE (Q54823) |
|
|
0.0 |
845 |
100% |
|
- Product
- DnrQ protein
- Gene
- dnrQ
- Organism
- Streptomyces peucetius
|
1uniprot[Pubmed] 7592454 [Medline] 96062261 Cloning and characterization of the Streptomyces peucetius dnrQS genes encoding a daunosamine biosynthesis enzyme and a glycosyl transferase involved in daunorubicin biosynthesis.(J. Bacteriol.) [1995] |
|
2
|
Q9L4U5_9ACTO (Q9L4U5) |
|
|
3e-64 |
251 |
40% |
|
- Product
- AknT
- Gene
- aknT
- Organism
- Streptomyces galilaeus
|
1uniprot[Pubmed] 11016846 [Medline] 20469061 A gene cluster from Streptomyces galilaeus involved in glycosylation of aclarubicin.(Mol. Gen. Genet.) [2000] |
|
3
|
Q2PZR5_9ACTO (Q2PZR5) |
|
|
6e-62 |
243 |
41% |
|
- Product
- CosT
- Gene
- cosT
- Organism
- Streptomyces olindensis
|
1uniprot[Pubmed] 16810496 Insights in the glycosylation steps during biosynthesis of the antitumor anthracycline cosmomycin: characterization of two glycosyltransferase genes.(Appl. Microbiol. Biotechnol.) [2006] |
|
8
|
Q2P9Y8_9ACTO (Q2P9Y8) |
|
|
3e-47 |
194 |
38% |
|
- Product
- Cytochrome P450-like
- Gene
- stfPII
- Organism
- Streptomyces steffisburgensis
|
1uniprot[Pubmed] 16751529 Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin.(Appl. Environ. Microbiol.) [2006] |
|
10
|
Q83WE0_MICGR (Q83WE0) |
|
|
4e-43 |
180 |
37% |
|
- Product
- Tautomerase
- Gene
- mydC
- Organism
- Micromonospora griseorubida
|
1uniprot[Pubmed] 12583909 [Medline] 22472038 Organization of the biosynthetic gene cluster for the polyketide macrolide mycinamicin in Micromonospora griseorubida.(FEMS Microbiol. Lett.) [2003] |
|
11
|
Q55218_STRSQ (Q55218) |
|
|
1e-42 |
179 |
94% |
|
- Product
- DauQ protein
- Gene
- dauQ
- Organism
- Streptomyces sp
|
1uniprot[Pubmed] 7836284 [Medline] 95138010 Analysis of clustered genes encoding both early and late steps in daunomycin biosynthesis by Streptomyces sp. strain C5.(J. Bacteriol.) [1995] |
|
12
|
Q9ZGH8_9ACTO (Q9ZGH8) |
|
|
3e-42 |
177 |
39% |
|
- Product
- Putative tautomerase
- Gene
- desVIII
- Organism
- Streptomyces venezuelae
|
1uniprot[Pubmed] 9770448 [Medline] 98445333 A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998] |
|
13
|
A8Y8F6_STRAM (A8Y8F6) |
|
|
8e-37 |
159 |
36% |
|
- Product
- Probable glycosyltransferase auxiliary protein
- Gene
- srm2*c
- Organism
- Streptomyces ambofaciens
|
1uniprot Organization of the biosynthetic gene cluster for the macrolide antibiotic spiramycin in Streptomyces ambofaciens.(Microbiology (Mosc.)) [2007] |
|
14
|
Q5SFA9_STRBI (Q5SFA9) |
|
|
2e-36 |
158 |
34% |
|
- Product
- Putative NDP-hexose 3,4-isomerase
- Gene
- chmCII
- Organism
- Streptomyces bikiniensis
|
1uniprot[Pubmed] 15561847 Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.(Antimicrob. Agents Chemother.) [2004] |
|
15
|
A0ACI4_STRAM (A0ACI4) |
|
|
3e-34 |
151 |
30% |
|
- Product
- Putative cytochrome P450
- Gene
- SAMR0478
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
16
|
A8Y8I0_STRAM (A8Y8I0) |
|
|
5e-34 |
150 |
37% |
|
- Product
- Probable glycosyltransferase auxiliary protein
- Gene
- srm16
- Organism
- Streptomyces ambofaciens
|
1uniprot Organization of the biosynthetic gene cluster for the macrolide antibiotic spiramycin in Streptomyces ambofaciens.(Microbiology (Mosc.)) [2007] |
|
17
|
D7AUQ9_NOCDD (D7AUQ9) |
|
|
1e-32 |
145 |
34% |
|
- Product
- Cytochrome P450
- Gene
- Ndas_2217
- Organism
- Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
|
1uniprot Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010] |
|
18
|
Q9RN55_STRNO (Q9RN55) |
|
|
6e-32 |
143 |
39% |
|
- Product
- SnogN
- Gene
- snogN
- Organism
- Streptomyces nogalater
|
1uniprot[Pubmed] 9349712 [Medline] 98007868 Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.(Mol. Gen. Genet.) [1997] | 2uniprot[Pubmed] 10639368 [Medline] 20106987 Identification of a cyclase gene dictating the C-9 stereochemistry of anthracyclines from Streptomyces nogalater.(Antimicrob. Agents Chemother.) [2000] | [pubmed all]
|
19
|
C7PYJ5_CATAD (C7PYJ5) |
|
|
5e-31 |
140 |
30% |
|
- Product
- Cytochrome P450
- Gene
- Caci_8494
- Organism
- Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
|
1uniprot Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009] |
|
20
|
A4FM47_SACEN (A4FM47) |
|
|
8e-31 |
139 |
31% |
|
- Product
- Cytochrome p450-like enzyme
- Gene
- bioI
SACE_5939
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
22
|
B2HLE0_MYCMM (B2HLE0) |
|
|
2e-29 |
135 |
31% |
|
- Product
- Cytochrome P450 164A3 Cyp164A3
- Gene
- cyp164A3
MMAR_5268
- Organism
- Mycobacterium marinum (strain ATCC BAA-535 / M)
|
1uniprot[Pubmed] 18403782 Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.(Genome Res.) [2008] |
|
26
|
Q9CBE7_MYCLE (Q9CBE7) |
|
|
8e-28 |
129 |
32% |
|
- Product
- Putative cytochrome p450
- Gene
- ML2088
- Organism
- Mycobacterium leprae
|
1uniprot[Pubmed] 11234002 [Medline] 21128732 Massive gene decay in the leprosy bacillus.(Nature) [2001] |
|
27
|
B8ZSP5_MYCLB (B8ZSP5) |
|
|
8e-28 |
129 |
32% |
|
- Product
- Putative cytochrome p450
- Gene
- MLBr02088
- Organism
- Mycobacterium leprae (strain Br4923)
|
1uniprot[Pubmed] 19881526 Comparative genomic and phylogeographic analysis of Mycobacterium leprae.(Nat. Genet.) [2009] |
|
28
|
Q331Q1_9ACTO (Q331Q1) |
|
|
2e-27 |
128 |
32% |
|
- Product
- NDP-hexose-3,4-isomerase
- Gene
- gerY
- Organism
- Streptomyces sp. KCTC 0041BP
|
1uniprot[Pubmed] 17053005 Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007] | 2uniprot Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006] |
|
30
|
D4G097_BACNA (D4G097) |
|
|
3e-27 |
127 |
25% |
|
- Product
- Cytochrome P450 enzyme
- Gene
- bioI
BSNT_04397
- Organism
- Bacillus subtilis subsp. natto BEST195
|
1uniprot[Pubmed] 20398357 Whole genome assembly of a natto production strain Bacillus subtilis natto from very short read data.(BMC Genomics) [2010] |
|
31
|
BIOI_BACSU (P53554) |
|
|
4e-27 |
127 |
26% |
|
- Product
- Biotin biosynthesis cytochrome P450
- Gene
- bioI
CYP107H BSU30190
- Organism
- Bacillus subtilis
|
1uniprot[Pubmed] 8763940 [Medline] 96312354 Cloning, sequencing, and characterization of the Bacillus subtilis biotin biosynthetic operon.(J. Bacteriol.) [1996] | 2uniprot[Pubmed] 9387221 [Medline] 98048467 Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region.(Microbiology) [1997] | 3uniprot[Pubmed] 9384377 [Medline] 98044033 The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.(Nature) [1997] | 4uniprot[Pubmed] 11368323 Expression, purification, and characterization of BioI: a carbon-carbon bond cleaving cytochrome P450 involved in biotin biosynthesis in Bacillus subtilis.(Arch. Biochem. Biophys.) [2000] | 5uniprot[Pubmed] 11472016 Expression, purification and characterization of cytochrome P450 Biol: a novel P450 involved in biotin synthesis in Bacillus subtilis.(J. Biol. Inorg. Chem.) [2001] | 6uniprot[Pubmed] 15449931 Thermodynamic and biophysical characterization of cytochrome P450 BioI from Bacillus subtilis.(Biochemistry) [2004] | 7uniprot[Pubmed] 14737344 Carbon-carbon bond cleavage by cytochrome p450(BioI)(CYP107H1).(Chem. Commun. (Camb.)) [2004] | 8uniprot[Pubmed] 18838690 Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex.(Proc. Natl. Acad. Sci. U.S.A.) [2008] | [pubmed all]
|
32
|
Q8KZM6_BACSU (Q8KZM6) |
|
|
4e-27 |
127 |
25% |
|
- Product
- Cytochrome P450 enzyme
- Gene
- bioI
- Organism
- Bacillus subtilis
|
1uniprot[Pubmed] 15056910 Genetic analysis of an incomplete bio operon in a biotin auxotrophic strain of Bacillus subtilis natto OK2.(Biosci. Biotechnol. Biochem.) [2004] |
|
33
|
O32927_MYCLE (O32927) |
|
|
5e-27 |
127 |
32% |
|
- Product
- Cytochrome p450
- Gene
- MLCB1788.51c
- Organism
- Mycobacterium leprae
|
1uniprot[Pubmed] 8446027 [Medline] 93188700 Use of an ordered cosmid library to deduce the genomic organization of Mycobacterium leprae.(Mol. Microbiol.) [1993] |
|
34
|
A0ACI5_STRAM (A0ACI5) |
|
|
5e-27 |
127 |
31% |
|
- Product
- Putative cytochrome P450
- Gene
- SAMR0479
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
35
|
C6WGZ2_ACTMD (C6WGZ2) |
|
|
7e-27 |
126 |
33% |
|
- Product
- Cytochrome P450
- Gene
- Amir_2115
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
36
|
E8VHT9_BACST (E8VHT9) |
|
|
8e-27 |
126 |
26% |
|
- Product
- Cytochrome P450 for pimelic acid formation for biotin biosynthesis
- Gene
- BSn5_05935
- Organism
- Bacillus subtilis (strain BSn5)
|
1uniprot[Pubmed] 21317323 Complete genome sequence of Bacillus subtilis BSn5, an endophytic bacterium of Amorphophallus konjac with antimicrobial activity to plant pathogen Erwinia carotovora subsp. carotovora.(J. Bacteriol.) [2011] |
|
37
|
P95746_STRFR (P95746) |
|
|
7e-26 |
123 |
34% |
|
- Product
- Hypothetical NDP hexose 3,4 isomerase
- Gene
- tylMIII(orf1*)
- Organism
- Streptomyces fradiae
Streptomyces roseoflavus
|
1uniprot[Pubmed] 9031628 [Medline] 97183662 Analysis of four tylosin biosynthetic genes from the tylLM region of Streptomyces fradiae.(Gene) [1997] |
|
38
|
Q0PY16_STRMY (Q0PY16) |
|
|
1e-25 |
122 |
33% |
|
- Product
- Putative NDP-hexose 3,4-isomerase
- Gene
- midH
- Organism
- Streptomyces mycarofaciens
|
1uniprot[Pubmed] 17342257 Cloning and characterization of genes encoded in dTDP-D-mycaminose biosynthetic pathway from a midecamycin-producing strain, Streptomyces mycarofaciens.(Acta Biochim. Biophys. Sin.) [2007] |
|
41
|
Q82A10_STRAW (Q82A10) |
|
|
2e-25 |
122 |
32% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- cyp23
SAV6249 SAV_6249
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
42
|
O87829_STRAT (O87829) |
|
|
2e-25 |
121 |
31% |
|
- Product
- Cytochrome P450 monooxygenase
- Gene
- oleP1
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 9749673 [Medline] 98420102 Analysis of a Streptomyces antibioticus chromosomal region involved in oleandomycin biosynthesis, which encodes two glycosyltransferases responsible for glycosylation of the macrolactone ring.(Mol. Gen. Genet.) [1998] |
|
45
|
F2LRH1_BURGA (F2LRH1) |
|
|
4e-25 |
120 |
27% |
|
- Product
- Cytochrome P-450 like protein
- Gene
- bgla_1p0600
- Organism
- Burkholderia gladioli BSR3
|
1uniprot[Pubmed] 21478339 Complete Genome Sequence of Burkholderia gladioli BSR3.(J. Bacteriol.) [2011] |
|
49
|
Q744J7_MYCPA (Q744J7) |
|
|
7e-25 |
120 |
30% |
|
- Product
- Putative uncharacterized protein
- Gene
- MAP_0344c
- Organism
- Mycobacterium paratuberculosis
|
1uniprot[Pubmed] 16116077 The complete genome sequence of Mycobacterium avium subspecies paratuberculosis.(Proc. Natl. Acad. Sci. U.S.A.) [2005] |
|
53
|
A7Z5B1_BACA2 (A7Z5B1) |
|
|
2e-24 |
118 |
28% |
|
- Product
- BioI
- Gene
- bioI
RBAM_018240
- Organism
- Bacillus amyloliquefaciens (strain FZB42)
|
1uniprot[Pubmed] 17704766 Comparative analysis of the complete genome sequence of the plant growth-promoting bacterium Bacillus amyloliquefaciens FZB42.(Nat. Biotechnol.) [2007] |
|
54
|
Q70JZ2_BACAM (Q70JZ2) |
|
|
2e-24 |
118 |
28% |
|
- Product
- BioI protein
- Gene
- bioI
- Organism
- Bacillus amyloliquefaciens
Bacillus velezensis
|
1uniprot[Pubmed] 14762003 Structural and functional characterization of gene clusters directing nonribosomal synthesis of bioactive cyclic lipopeptides in Bacillus amyloliquefaciens strain FZB42.(J. Bacteriol.) [2004] |
|
60
|
D2B7E9_STRRD (D2B7E9) |
|
|
8e-24 |
116 |
31% |
|
- Product
- Cytochrome P450 family protein
- Gene
- Sros_8837
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
67
|
A9G3Q4_SORC5 (A9G3Q4) |
|
|
4e-23 |
114 |
30% |
|
- Product
- Cytochrome P450 CYP266A1
- Gene
- cypA4
sce5624
- Organism
- Sorangium cellulosum (strain So ce56)
Polyangium cellulosum (strain So ce56)
|
1uniprot[Pubmed] 17965706 Complete genome sequence of the myxobacterium Sorangium cellulosum.(Nat. Biotechnol.) [2007] |
|
74
|
Q9X8Q3_STRCO (Q9X8Q3) |
|
|
2e-22 |
112 |
30% |
|
- Product
- Putative cytochrome P-450 hydroxylase
- Gene
- SCO3636
- Organism
- Streptomyces coelicolor
|
1uniprot[Pubmed] 12000953 [Medline] 21996410 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002] |
|
78
|
C7CJA5_METED (C7CJA5) |
|
|
3e-22 |
111 |
32% |
|
- Product
- Putative cytochrome P450 reductase
- Gene
- METDI4994
- Organism
- Methylobacterium extorquens (strain DSM 5838 / DM4)
Methylobacterium dichloromethanicum (strain DM4)
|
1uniprot[Pubmed] 19440302 Methylobacterium genome sequences: a reference blueprint to investigate microbial metabolism of C1 compounds from natural and industrial sources.(PLoS ONE) [2009] |
|
79
|
A8L4G2_FRASN (A8L4G2) |
|
|
4e-22 |
110 |
33% |
|
- Product
- Cytochrome P450
- Gene
- Franean1_3940
- Organism
- Frankia sp. (strain EAN1pec)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
80
|
Q73YC3_MYCPA (Q73YC3) |
|
|
4e-22 |
110 |
28% |
|
- Product
- Putative uncharacterized protein
- Gene
- MAP_2033
- Organism
- Mycobacterium paratuberculosis
|
1uniprot[Pubmed] 16116077 The complete genome sequence of Mycobacterium avium subspecies paratuberculosis.(Proc. Natl. Acad. Sci. U.S.A.) [2005] |
|
81
|
Q0QMN1_9ACTO (Q0QMN1) |
|
|
4e-22 |
110 |
27% |
|
- Product
- Cytochrome P450
- Gene
-
- Organism
- Streptomyces sp. Eco86
|
1uniprot[Pubmed] 16724457 Isolation and identification of three new 5-alkenyl-3,3(2H)-furanones from two streptomyces species using a genomic screening approach.(J. Antibiot.) [2006] |
|
82
|
C5B2Z1_METEA (C5B2Z1) |
|
|
5e-22 |
110 |
32% |
|
- Product
- Putative cytochrome P450 reductase
- Gene
- MexAM1_META1p4388
- Organism
- Methylobacterium extorquens (strain ATCC 14718 / DSM 1338 / AM1)
|
1uniprot[Pubmed] 19440302 Methylobacterium genome sequences: a reference blueprint to investigate microbial metabolism of C1 compounds from natural and industrial sources.(PLoS ONE) [2009] |
|
90
|
Q1D4X1_MYXXD (Q1D4X1) |
|
|
2e-21 |
108 |
31% |
|
- Product
- Cytochrome P450 family protein
- Gene
- MXAN_4127
- Organism
- Myxococcus xanthus (strain DK 1622)
|
1uniprot[Pubmed] 17015832 Evolution of sensory complexity recorded in a myxobacterial genome.(Proc. Natl. Acad. Sci. U.S.A.) [2006] |
|
98
|
D8HUE4_AMYMU (D8HUE4) |
|
|
9e-21 |
106 |
33% |
|
- Product
- Cytochrome P450
- Gene
- AMED_0142
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
99
|
A4FH88_SACEN (A4FH88) |
|
|
9e-21 |
106 |
34% |
|
- Product
- Cytochrome P450 monooxygenase
- Gene
- SACE_4144
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
100
|
Q5VKQ6_SACER (Q5VKQ6) |
|
|
9e-21 |
106 |
34% |
|
- Product
- P450 monooxygenase
- Gene
- pkePI
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15925898 A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004] |
|