| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
D1GLV7_9ACTO (D1GLV7) |
|
|
0.0 |
6700 |
100% |
|
- Product
- Polyketide synthase type I
- Gene
- slgA3
- Organism
- Streptomyces lydicus
|
1uniprot Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009] |
|
2
|
F1DI33_9ACTO (F1DI33) |
|
(4 hsp) |
0.0 |
3217 |
63% |
|
- Product
- TrdAIII
- Gene
-
- Organism
- Streptomyces sp. SCSIO1666
|
1uniprot[Pubmed] 21329667 Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011] |
|
3
|
D3Y1I5_9ACTO (D3Y1I5) |
|
(4 hsp) |
0.0 |
3215 |
63% |
|
- Product
- TamAIII
- Gene
-
- Organism
- Streptomyces sp. 307-9
|
1uniprot[Pubmed] 20127927 Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010] |
|
5
|
Q52V46_9ACTO (Q52V46) |
|
(10 hsp) |
0.0 |
3036 |
54% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
7
|
F1CLA9_9ACTO (F1CLA9) |
|
(9 hsp) |
0.0 |
2917 |
52% |
|
- Product
- ScnS2
- Gene
- scnS2
- Organism
- Streptomyces chattanoogensis
|
1uniprot[Pubmed] 21330439 The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011] |
|
9
|
Q93NX9_9ACTO (Q93NX9) |
|
(9 hsp) |
0.0 |
2910 |
52% |
|
- Product
- AmphI
- Gene
- amphI
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|
10
|
Q52V44_9ACTO (Q52V44) |
|
(6 hsp) |
0.0 |
2904 |
52% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
12
|
D7C2C3_STRBB (D7C2C3) |
|
(4 hsp) |
0.0 |
2895 |
52% |
|
- Product
- Modular polyketide synthase
- Gene
- pks3-4
SBI_00656
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
15
|
Q9EWA1_9ACTO (Q9EWA1) |
|
(10 hsp) |
0.0 |
2833 |
52% |
|
- Product
- PimS2 protein
- Gene
- pimS2
- Organism
- Streptomyces natalensis
|
1uniprot[Pubmed] 11094342 [Medline] 20547809 A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000] |
|
16
|
Q52V45_9ACTO (Q52V45) |
|
|
0.0 |
2833 |
52% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
19
|
Q30CR9_STRAU (Q30CR9) |
|
|
0.0 |
2823 |
53% |
|
- Product
- LipPks4
- Gene
- lipPks4
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 16723573 Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006] |
|
21
|
Q9L4X3_9ACTO (Q9L4X3) |
|
(10 hsp) |
0.0 |
2793 |
52% |
|
- Product
- NysI
- Gene
- nysI
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
24
|
Q6W5P6_9ACTO (Q6W5P6) |
|
(10 hsp) |
0.0 |
2738 |
51% |
|
- Product
- FscD
- Gene
- fscD
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
25
|
Q52V50_9ACTO (Q52V50) |
|
(9 hsp) |
0.0 |
2737 |
58% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
27
|
D2CKL5_PSEAH (D2CKL5) |
|
(10 hsp) |
0.0 |
2717 |
51% |
|
- Product
- CppI
- Gene
- cppI
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 19697072 Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009] |
|
29
|
Q52V53_9ACTO (Q52V53) |
|
(7 hsp) |
0.0 |
2715 |
57% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
30
|
Q52V49_9ACTO (Q52V49) |
|
(4 hsp) |
0.0 |
2703 |
56% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
31
|
Q9ALM3_9PSEU (Q9ALM3) |
|
(3 hsp) |
0.0 |
2699 |
49% |
|
- Product
- Polyketide synthase extender modules 5-7
- Gene
- spnD
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001] |
|
33
|
F1CLC1_9ACTO (F1CLC1) |
|
(9 hsp) |
0.0 |
2677 |
56% |
|
- Product
- ScnS1
- Gene
- scnS1
- Organism
- Streptomyces chattanoogensis
|
1uniprot[Pubmed] 21330439 The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011] |
|
34
|
Q52V52_9ACTO (Q52V52) |
|
(6 hsp) |
0.0 |
2659 |
57% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
35
|
D7C2B8_STRBB (D7C2B8) |
|
(11 hsp) |
0.0 |
2654 |
56% |
|
- Product
- Type I modular polyketide synthase
- Gene
- pks3-2
SBI_00651
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
36
|
Q30CS0_STRAU (Q30CS0) |
|
(5 hsp) |
0.0 |
2642 |
55% |
|
- Product
- LipPks3
- Gene
- lipPks3
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 16723573 Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006] |
|
37
|
Q9X993_9ACTO (Q9X993) |
|
(9 hsp) |
0.0 |
2630 |
56% |
|
- Product
- PimS1 protein
Polyketide synthase
- Gene
- pimS1
- Organism
- Streptomyces natalensis
|
1uniprot[Pubmed] 10187796 [Medline] 99214571 The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999] | 2uniprot[Pubmed] 11094342 [Medline] 20547809 A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000] | [pubmed all]
|
40
|
A4FH83_SACEN (A4FH83) |
|
(7 hsp) |
0.0 |
2610 |
49% |
|
- Product
- Type I modular polyketide synthase
- Gene
- SACE_4139
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
41
|
Q5VKR4_SACER (Q5VKR4) |
|
(7 hsp) |
0.0 |
2610 |
49% |
|
- Product
- Type I PKS
- Gene
- pkeAIII
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15925898 A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004] |
|
42
|
D7BRD4_STRBB (D7BRD4) |
|
(14 hsp) |
0.0 |
2605 |
56% |
|
- Product
- Short-chain dehydrogenase/reductase SDR
- Gene
- SBI_01976
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
43
|
Q93NW6_9ACTO (Q93NW6) |
|
(14 hsp) |
0.0 |
2599 |
56% |
|
- Product
- AmphC
- Gene
- amphC
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|
44
|
Q9L4W3_9ACTO (Q9L4W3) |
|
(15 hsp) |
0.0 |
2591 |
56% |
|
- Product
- NysC
- Gene
- nysC
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
46
|
Q6W5Q0_9ACTO (Q6W5Q0) |
|
(14 hsp) |
0.0 |
2572 |
56% |
|
- Product
- FscC
- Gene
- fscC
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
47
|
Q82QT4_STRAW (Q82QT4) |
|
(12 hsp) |
0.0 |
2563 |
55% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA1
SAV419 SAV_419
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
48
|
D7BRE0_STRBB (D7BRE0) |
|
(6 hsp) |
0.0 |
2556 |
55% |
|
- Product
- Modular polyketide synthase
- Gene
- SBI_01982
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
49
|
A4FH85_SACEN (A4FH85) |
|
(7 hsp) |
0.0 |
2554 |
48% |
|
- Product
- Type I modular polyketide synthase
- Gene
- SACE_4141
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
50
|
Q5VKQ3_SACER (Q5VKQ3) |
|
(7 hsp) |
0.0 |
2554 |
48% |
|
- Product
- Type I PKS
- Gene
- pkeAI
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15925898 A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004] |
|
51
|
Q9EX53_STRCO (Q9EX53) |
|
(5 hsp) |
0.0 |
2551 |
52% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCO6274
- Organism
- Streptomyces coelicolor
|
1uniprot[Pubmed] 12000953 [Medline] 21996410 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002] |
|
54
|
A0ACH3_STRAM (A0ACH3) |
|
(9 hsp) |
0.0 |
2508 |
48% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SAMR0467
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
55
|
B6ZIR3_STRPT (B6ZIR3) |
|
(9 hsp) |
0.0 |
2503 |
47% |
|
- Product
- Polyketide synthase
- Gene
- pldAII
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
56
|
Q93NX8_9ACTO (Q93NX8) |
|
(7 hsp) |
0.0 |
2502 |
54% |
|
- Product
- AmphJ
- Gene
- amphJ
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|
59
|
Q0R4M7_STRAT (Q0R4M7) |
|
(5 hsp) |
0.0 |
2491 |
51% |
|
- Product
- ChlA2
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006] |
|
60
|
Q6JHN6_9PSEU (Q6JHN6) |
|
(9 hsp) |
0.0 |
2476 |
53% |
|
- Product
- ObsC
- Gene
-
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 15346767 Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004] |
|
61
|
C5HV16_STRAT (C5HV16) |
|
(4 hsp) |
0.0 |
2469 |
47% |
|
- Product
- Polyketide synthase
- Gene
- idmN
- Organism
- Streptomyces antibioticus
|
1uniprot Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009] |
|
62
|
Q9ALM2_9PSEU (Q9ALM2) |
|
(7 hsp) |
0.0 |
2459 |
52% |
|
- Product
- Polyketide synthase extender modules 8-10
- Gene
- spnE
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001] |
|
63
|
Q1WEK8_9ACTO (Q1WEK8) |
|
(7 hsp) |
0.0 |
2454 |
47% |
|
- Product
- Polyketide synthase
- Gene
- merB
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
65
|
Q1WEK9_9ACTO (Q1WEK9) |
|
(9 hsp) |
0.0 |
2450 |
48% |
|
- Product
- Polyketide synthase
- Gene
- merA
- Organism
- Streptomyces sp. NRRL 30748
|
1uniprot[Pubmed] 16806745 Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006] |
|
68
|
D2CKM4_PSEAH (D2CKM4) |
|
(13 hsp) |
0.0 |
2435 |
55% |
|
- Product
- CppC
- Gene
- cppC
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 19697072 Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009] |
|
69
|
C3VLV4_9ACTO (C3VLV4) |
|
(9 hsp) |
0.0 |
2434 |
51% |
|
- Product
- Polyketide synthase type I
- Gene
- becA
- Organism
- Streptomyces sp. DSM 21069
|
1uniprot[Pubmed] 19875084 Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009] |
|
71
|
Q1L0T1_STRHY (Q1L0T1) |
|
|
0.0 |
2420 |
46% |
|
- Product
- GelB
- Gene
-
- Organism
- Streptomyces hygroscopicus subsp. duamyceticus
|
1uniprot[Pubmed] 18600054 Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008] |
|
72
|
Q84G23_STRHY (Q84G23) |
|
|
0.0 |
2417 |
46% |
|
- Product
- GdmAII
- Gene
- gdmAII
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 12586396 [Medline] 22474162 Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003] |
|
73
|
Q49BE0_STRHY (Q49BE0) |
|
|
0.0 |
2417 |
46% |
|
- Product
- HbmAII
- Gene
- hbmAII
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 16085885 Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.(Appl. Environ. Microbiol.) [2005] |
|
74
|
A4FCY9_SACEN (A4FCY9) |
|
(8 hsp) |
0.0 |
2417 |
52% |
|
- Product
- Modular polyketide synthase
- Gene
- SACE_2630
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
75
|
C6WNV0_ACTMD (C6WNV0) |
|
(8 hsp) |
0.0 |
2415 |
53% |
|
- Product
- Short-chain dehydrogenase/reductase SDR
- Gene
- Amir_2684
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
76
|
Q0R4M5_STRAT (Q0R4M5) |
|
(8 hsp) |
0.0 |
2414 |
51% |
|
- Product
- ChlA3
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006] |
|
77
|
A4FH84_SACEN (A4FH84) |
|
(5 hsp) |
0.0 |
2410 |
53% |
|
- Product
- Type I modular polyketide synthase
- Gene
- SACE_4140
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
78
|
Q5VKQ8_SACER (Q5VKQ8) |
|
(5 hsp) |
0.0 |
2410 |
53% |
|
- Product
- Type I PKS
- Gene
- pkeAII
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15925898 A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004] |
|
80
|
B6ZIR2_STRPT (B6ZIR2) |
|
(11 hsp) |
0.0 |
2408 |
52% |
|
- Product
- Polyketide synthase
- Gene
- pldAI
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
81
|
C3VLY1_9ACTO (C3VLY1) |
|
(10 hsp) |
0.0 |
2403 |
51% |
|
- Product
- Polyketide synthase type I
- Gene
- mlaA1
- Organism
- Streptomyces sp. MP39-85
|
1uniprot[Pubmed] 19854930 Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010] |
|
82
|
C6WN16_ACTMD (C6WN16) |
|
(9 hsp) |
0.0 |
2397 |
53% |
|
- Product
- Mycocerosate synthase., Erythronolide synthase
- Gene
- Amir_4699
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
83
|
Q82QT5_STRAW (Q82QT5) |
|
(6 hsp) |
0.0 |
2394 |
52% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA2
SAV418 SAV_418
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
84
|
C6WNW1_ACTMD (C6WNW1) |
|
(11 hsp) |
0.0 |
2381 |
53% |
|
- Product
- Short-chain dehydrogenase/reductase SDR
- Gene
- Amir_2695
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
85
|
Q93H86_STRAW (Q93H86) |
|
(6 hsp) |
0.0 |
2376 |
52% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA2
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
87
|
Q0R4M8_STRAT (Q0R4M8) |
|
(9 hsp) |
0.0 |
2368 |
51% |
|
- Product
- ChlA1
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006] |
|
89
|
Q30CS1_STRAU (Q30CS1) |
|
(5 hsp) |
0.0 |
2362 |
52% |
|
- Product
- LipPks2
- Gene
- lipPks2
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 16723573 Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006] |
|
90
|
D3U9Y8_9ACTO (D3U9Y8) |
|
(10 hsp) |
0.0 |
2358 |
49% |
|
- Product
- Type I polyketide synthase
- Gene
- sfaH
- Organism
- Streptomyces flaveolus
|
1uniprot Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010] |
|
91
|
A0FCL2_STRVO (A0FCL2) |
|
(8 hsp) |
0.0 |
2355 |
46% |
|
- Product
- MerB
- Gene
- merB
- Organism
- Streptomyces violaceoniger
|
1uniprot[Pubmed] 17159202 Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006] |
|
92
|
B1W485_STRGG (B1W485) |
|
(4 hsp) |
0.0 |
2354 |
47% |
|
- Product
- Putative type-I PKS
- Gene
- pks1-1
SGR_6073
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
96
|
Q6V1M7_9ACTO (Q6V1M7) |
|
|
0.0 |
2310 |
46% |
|
- Product
- Plm2-3
- Gene
- plm2-3
- Organism
- Streptomyces sp. HK803
|
1uniprot[Pubmed] 12819191 [Medline] 22841069 Enhancement and selective production of phoslactomycin B, a protein phosphatase IIa inhibitor, through identification and engineering of the corresponding biosynthetic gene cluster.(J. Biol. Chem.) [2003] |
|
97
|
C6ZCS0_9ACTO (C6ZCS0) |
|
(10 hsp) |
0.0 |
2305 |
46% |
|
- Product
- Type I modular polyketide synthase
- Gene
- ttnB
- Organism
- Streptomyces griseochromogenes
|
1uniprot[Pubmed] 19191560 Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009] |
|
98
|
Q6JHN7_9PSEU (Q6JHN7) |
|
(7 hsp) |
0.0 |
2304 |
51% |
|
- Product
- ObsB
- Gene
-
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 15346767 Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004] |
|
99
|
A4KCE5_9ACTO (A4KCE5) |
|
(10 hsp) |
0.0 |
2304 |
46% |
|
- Product
- Tautomycetin biosynthetic PKS
- Gene
-
- Organism
- Streptomyces sp. CK4412
|
1uniprot[Pubmed] 17379718 Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007] | 2uniprot[Pubmed] 20623733 Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.(Angew. Chem. Int. Ed.) [2010] | [pubmed all]
|