BLAST table : Teicp_00340

DB	UniProtKB

	accession	Evalue	Score	Ident.	link	product	gene	organism	ec
1	Q6ZZH4_ACTTI (Q6ZZH4)	0.0	845	100%	UniProt GenBank	DpgC protein	tcp32	Actinoplanes teichomyceticus
2	E9L1J0_9ZZZZ (E9L1J0)	0.0	748	88%	UniProt GenBank	Putative uncharacterized protein	CA37-46	uncultured organism CA37
3	E9L1U1_9ZZZZ (E9L1U1)	1e-180	636	79%	UniProt GenBank	Putative uncharacterized protein	CA915-49	uncultured organism CA915
4	Q939X1_9PSEU (Q939X1)	1e-153	545	68%	UniProt GenBank	Hydroxyacyl-dehydrogenase	dpgC	Amycolatopsis balhimycina
5	O52812_AMYOR (O52812)	1e-151	539	64%	UniProt GenBank	PCZA361.8		Amycolatopsis orientalis Nocardia orientalis
6	Q8KLK7_STRTO (Q8KLK7)	1e-151	539	70%	UniProt GenBank	DpgC		Streptomyces toyocaensis
7	Q7WZ58_9ACTO (Q7WZ58)	1e-150	535	67%	UniProt GenBank	Putative DpgC protein	dbv33	Nonomuraea sp. ATCC 39727
8	Q2JA69_FRASC (Q2JA69)	1e-148	528	69%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Francci3_2456	Frankia sp. (strain CcI3)
9	B7T1B1_9BACT (B7T1B1)	1e-145	521	69%	UniProt GenBank	Veg39	veg39	uncultured soil bacterium
10	E9L1P1_9ZZZZ (E9L1P1)	1e-145	519	69%	UniProt GenBank	Putative uncharacterized protein	CA878-42	uncultured organism CA878
11	E2D2E7_9BACT (E2D2E7)	1e-143	514	68%	UniProt GenBank	Dihydroxyphenylglycine synthase subunit C		uncultured soil bacterium
12	F8STZ8_AMYOR (F8STZ8)	1e-142	508	67%	UniProt GenBank	Hydroxyacyl-dehydrogenase	vcm25	Amycolatopsis orientalis Nocardia orientalis
13	F2R790_STRVP (F2R790)	1e-128	462	61%	UniProt GenBank	Enoyl-CoA hydratase or isomerase	SVEN_0495	Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
14	D7B4X5_NOCDD (D7B4X5)	1e-127	460	58%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Ndas_1737	Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei
15	D9UHH7_9ACTO (D9UHH7)	1e-125	452	58%	UniProt GenBank	Hydroxyacyl-dehydrogenase	SSLG_05413	Streptomyces sp. SPB78
16	C0Z469_STRVN (C0Z469)	1e-117	425	57%	UniProt GenBank	Dioxygenase	ken4	Streptomyces violaceoruber
17	F3ZDK5_9ACTO (F3ZDK5)	1e-111	407	62%	UniProt GenBank	Putative enoyl-CoA hydratase/isomerase	STTU_1158	Streptomyces sp. Tu6071
18	D6A5M8_9ACTO (D6A5M8)	1e-107	394	53%	UniProt GenBank	DpgC protein	SSFG_06976	Streptomyces ghanaensis ATCC 14672
19	F3NRX6_9ACTO (F3NRX6)	1e-107	393	53%	UniProt GenBank	Putative enoyl-CoA hydratase/isomerase	SGM_5890	Streptomyces griseoaurantiacus M045
20	D0RB78_STRPR (D0RB78)	1e-100	371	50%	UniProt GenBank	Hydroxyacyl-dehydrogenase Putative hydroxyacyl-dehydrogenase	pglA	Streptomyces pristinaespiralis
21	B5HJU2_STRPR (B5HJU2)	1e-100	371	50%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	SSDG_05431	Streptomyces pristinaespiralis ATCC 25486
22	D2UD62_XANAP (D2UD62)	5e-98	362	49%	UniProt GenBank	Putative enoyl-coa hydratase isomerase protein	XALc_1061	Xanthomonas albilineans (strain GPE PC73 / CFBP 7063)
23	D2PSN9_KRIFD (D2PSN9)	1e-93	348	52%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Kfla_4130	Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)
24	Q9RPT2_9BACT (Q9RPT2)	2e-59	234	48%	UniProt GenBank	Putative uncharacterized protein		uncultured bacterium AH6
25	E9LIP8_9ACTO (E9LIP8)	7e-38	163	38%	UniProt GenBank	Putative enoyl-CoA hydratase/isomerase	tiaN	Dactylosporangium aurantiacum subsp. hamdenensis
26	Q8KLK8_STRTO (Q8KLK8)	1e-17	95.9	32%	UniProt GenBank	DpgD		Streptomyces toyocaensis
27	Q939X0_9PSEU (Q939X0)	2e-17	95.1	35%	UniProt GenBank	Putative enoyl-CoA-isomerase	dpgD	Amycolatopsis balhimycina
28	B6AXC0_9RHOB (B6AXC0)	5e-17	94	32%	UniProt GenBank	Carnitinyl-CoA dehydratase	caiD RB2083_2722	Rhodobacteraceae bacterium HTCC2083
29	Q1NB15_9SPHN (Q1NB15)	1e-16	92.4	28%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	SKA58_07548	Sphingomonas sp. SKA58
30	E9L1P2_9ZZZZ (E9L1P2)	2e-16	92	34%	UniProt GenBank	Putative uncharacterized protein	CA878-43	uncultured organism CA878
31	Q5LPZ0_SILPO (Q5LPZ0)	2e-16	91.7	31%	UniProt GenBank	Carnitinyl-CoA dehydratase	caiD-1 SPO2706	Silicibacter pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)
32	D4Z2S5_SPHJU (D4Z2S5)	3e-16	91.3	30%	UniProt GenBank	Enoyl-CoA hydratase	paaG SJA_C1-20730	Sphingobium japonicum (strain NBRC 101211 / UT26S)	4.2.1.17 niceE keggE
33	Q08P39_STIAD (Q08P39)	4e-16	90.9	31%	UniProt GenBank	3-hydroxybutyryl-CoA dehydratase	STAUR_4349 STIAU_6570	Stigmatella aurantiaca (strain DW4/3-1)	4.2.1.55 niceE keggE
34	D1C1Z3_SPHTD (D1C1Z3)	4e-16	90.9	32%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Sthe_0823	Sphaerobacter thermophilus (strain DSM 20745 / S 6022)
35	F6INA6_9SPHN (F6INA6)	5e-16	90.5	28%	UniProt GenBank	Enoyl-CoA hydratase	PP1Y_AT20327	Novosphingobium sp. PP1Y	4.2.1.17 niceE keggE
36	Q7WZ57_9ACTO (Q7WZ57)	8e-16	89.7	32%	UniProt GenBank	Putative DpgD protein	dbv34	Nonomuraea sp. ATCC 39727
37	A5PAX2_9SPHN (A5PAX2)	8e-16	89.7	28%	UniProt GenBank	Enoyl-CoA hydratase/isomerase family protein	ED21_21894	Erythrobacter sp. SD-21
38	F1LCC6_ASCSU (F1LCC6)	8e-16	89.7	30%	UniProt GenBank	Enoyl-CoA hydratase		Ascaris suum Pig roundworm Ascaris lumbricoides
39	D3NY30_AZOS1 (D3NY30)	1e-15	89.4	31%	UniProt GenBank	Enoyl-CoA hydratase	paaG AZL_026710	Azospirillum sp. (strain B510)	4.2.1.17 niceE keggE
40	F1Z4G9_9SPHN (F1Z4G9)	1e-15	89.4	30%	UniProt GenBank	Short chain enoyl-CoA hydratase	Y88_2869	Novosphingobium nitrogenifigens DSM 19370
41	E2D2E8_9BACT (E2D2E8)	1e-15	89.4	32%	UniProt GenBank	Dihydroxyphenylglycine synthase subunit D		uncultured soil bacterium
42	Q2N892_ERYLH (Q2N892)	2e-15	89	29%	UniProt GenBank	Enoyl-CoA hydratase/isomerase family protein	ELI_10035	Erythrobacter litoralis (strain HTCC2594)
43	Q0AVM1_SYNWW (Q0AVM1)	2e-15	88.6	32%	UniProt GenBank	Short chain enoyl-CoA hydratase	Swol_1936	Syntrophomonas wolfei subsp. wolfei (strain Goettingen)	4.2.1.17 niceE keggE
44	B1KCQ8_BURCC (B1KCQ8)	3e-15	88.2	30%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Bcenmc03_6902	Burkholderia cenocepacia (strain MC0-3)
45	D9QGA0_BRESC (D9QGA0)	3e-15	88.2	31%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Bresu_3336	Brevundimonas subvibrioides (strain ATCC 15264 / DSM 4735 / LMG 14903 / NBRC 16000 / CB 81) Caulobacter subvibrioides
46	Q4LEY5_9ENTR (Q4LEY5)	4e-15	87.8	31%	UniProt GenBank	PaaF	paaF	Klebsiella sp. PAMU-1.2
47	B5WCE7_9BURK (B5WCE7)	4e-15	87.4	29%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	BH160DRAFT_0747	Burkholderia sp. H160
48	Q82Q04_STRAW (Q82Q04)	4e-15	87.4	33%	UniProt GenBank	Putative enoyl-CoA hydratase	echA3 SAV717 SAV_717	Streptomyces avermitilis
49	Q1ATI2_RUBXD (Q1ATI2)	4e-15	87.4	32%	UniProt GenBank	Short chain enoyl-CoA hydratase	Rxyl_2368	Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)	4.2.1.17 niceE keggE
50	F6EUP7_SPHCR (F6EUP7)	4e-15	87.4	28%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Sphch_1075	Sphingobium chlorophenolicum L-1
51	F3ZDK0_9ACTO (F3ZDK0)	4e-15	87.4	32%	UniProt GenBank	Putative enoyl-CoA hydratase	STTU_1153	Streptomyces sp. Tu6071
52	A5V769_SPHWW (A5V769)	6e-15	87	30%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Swit_1773	Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)
53	D8F324_9DELT (D8F324)	6e-15	87	28%	UniProt GenBank	Enoyl-CoA hydratase/isomerase family protein	NPH_7275	delta proteobacterium NaphS2
54	D0LYC9_HALO1 (D0LYC9)	7e-15	86.7	29%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Hoch_3779	Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2)
55	F2LNP5_BURGA (F2LNP5)	9e-15	86.7	30%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	bgla_2g20890	Burkholderia gladioli BSR3
56	B1JBL8_PSEPW (B1JBL8)	9e-15	86.3	30%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	PputW619_3454	Pseudomonas putida (strain W619)
57	A7IKJ4_XANP2 (A7IKJ4)	9e-15	86.3	29%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Xaut_3308	Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)
58	C2BE96_9FIRM (C2BE96)	1e-14	86.3	29%	UniProt GenBank	3-hydroxybutyryl-CoA dehydratase	crt HMPREF0072_0666	Anaerococcus lactolyticus ATCC 51172	4.2.1.55 niceE keggE
59	D9UHI4_9ACTO (D9UHI4)	1e-14	86.3	32%	UniProt GenBank	2-ketocyclohexanecarboxyl-CoA hydrolase	SSLG_05420	Streptomyces sp. SPB78
60	F1ZD15_9SPHN (F1ZD15)	1e-14	86.3	33%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Y88_3808	Novosphingobium nitrogenifigens DSM 19370
61	C7NG05_KYTSD (C7NG05)	1e-14	85.9	33%	UniProt GenBank	Short chain enoyl-CoA hydratase	Ksed_09590	Kytococcus sedentarius (strain ATCC 14392 / DSM 20547 / CCM 314 / 541) Micrococcus sedentarius
62	Q0AYU3_SYNWW (Q0AYU3)	1e-14	85.9	28%	UniProt GenBank	Short chain enoyl-CoA hydratase	Swol_0790	Syntrophomonas wolfei subsp. wolfei (strain Goettingen)	4.2.1.17 niceE keggE
63	E0MMC4_9RHOB (E0MMC4)	1e-14	85.9	28%	UniProt GenBank	Enoyl-CoA hydratase	R2A130_2520	Ahrensia sp. R2A130
64	E7C4A8_9ACTN (E7C4A8)	2e-14	85.5	27%	UniProt GenBank	Enoyl-CoA hydratase/carnithine racemase		uncultured actinobacterium HF0200_46I24
65	E7C432_9GAMM (E7C432)	2e-14	85.5	27%	UniProt GenBank	Enoyl-CoA hydratase/carnithine racemase		uncultured gamma proteobacterium HF0200_34B07
66	E7DDH9_ALCFA (E7DDH9)	2e-14	85.5	30%	UniProt GenBank	Enoyl-CoA hydratase family	acuK	Alcaligenes faecalis
67	D6Y6R2_THEBD (D6Y6R2)	2e-14	85.1	32%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Tbis_2854	Thermobispora bispora (strain ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / NBRC 14880 / R51)
68	Q1GNL3_SPHAL (Q1GNL3)	2e-14	85.1	29%	UniProt GenBank	Short chain enoyl-CoA hydratase	Sala_3055	Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256) Sphingomonas alaskensis	4.2.1.17 niceE keggE
69	A9B0Y0_HERA2 (A9B0Y0)	3e-14	84.7	28%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Haur_1202	Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785)
70	A3WEF3_9SPHN (A3WEF3)	3e-14	84.7	29%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	NAP1_10393	Erythrobacter sp. NAP1
71	A5V798_SPHWW (A5V798)	3e-14	84.3	29%	UniProt GenBank	Short chain enoyl-CoA hydratase	Swit_1803	Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)	4.2.1.17 niceE keggE
72	D0LD66_GORB4 (D0LD66)	3e-14	84.3	28%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Gbro_3355	Gordonia bronchialis (strain ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667) Rhodococcus bronchialis
73	A5V400_SPHWW (A5V400)	4e-14	84.3	29%	UniProt GenBank	Short chain enoyl-CoA hydratase	Swit_0648	Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)	4.2.1.17 niceE keggE
74	F7R876_SHIFL (F7R876)	4e-14	84.3	29%	UniProt GenBank	Putative enoyl-CoA hydratase	SFJ1713_1597	Shigella flexneri J1713
75	D5NEY7_9BURK (D5NEY7)	4e-14	84.3	32%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	BCh11DRAFT_2961	Burkholderia sp. Ch1-1
76	B8FC62_DESAA (B8FC62)	4e-14	84	30%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Dalk_3794	Desulfatibacillum alkenivorans (strain AK-01)	4.2.1.18 niceE keggE
77	E7C8P6_9GAMM (E7C8P6)	5e-14	84	28%	UniProt GenBank	Enoyl-CoA hydratase/carnithine racemase		uncultured gamma proteobacterium HF4000_47G05
78	F4A6J9_CLOBO (F4A6J9)	5e-14	84	27%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	CbC4_2221	Clostridium botulinum BKT015925	4.2.1.55 niceE keggE
79	A5Z9I6_9FIRM (A5Z9I6)	6e-14	84	29%	UniProt GenBank	Putative uncharacterized protein	EUBVEN_02382	Eubacterium ventriosum ATCC 27560
80	F2KGA1_PSEBN (F2KGA1)	7e-14	83.6	30%	UniProt GenBank	Putative enoyl-CoA hydratase	PSEBR_a2935	Pseudomonas brassicacearum (strain NFM421)
81	C5VNX5_CLOBO (C5VNX5)	7e-14	83.2	27%	UniProt GenBank	3-hydroxybutyryl-CoA dehydratase	CLG_B0355	Clostridium botulinum D str. 1873	4.2.1.55 niceE keggE
82	D3F4A0_CONWI (D3F4A0)	8e-14	83.2	36%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Cwoe_2046	Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 / ID131577)
83	E1IVW0_ECOLX (E1IVW0)	8e-14	83.2	29%	UniProt GenBank	Enoyl-CoA hydratase/isomerase family protein	HMPREF9348_04346	Escherichia coli MS 145-7
84	B3H843_ECOLX (B3H843)	8e-14	83.2	29%	UniProt GenBank	Enoyl-CoA hydratase PaaF	paaF EcB7A_0316	Escherichia coli B7A	4.2.1.17 niceE keggE
85	E7C4T8_9GAMM (E7C4T8)	8e-14	83.2	27%	UniProt GenBank	Enoyl-CoA hydratase/carnithine racemase		uncultured gamma proteobacterium HF0500_07A21
86	F5RRQ3_9ENTR (F5RRQ3)	9e-14	83.2	30%	UniProt GenBank	Enoyl-CoA hydratase	paaF2 HMPREF9086_0307	Enterobacter hormaechei ATCC 49162	4.2.1.17 niceE keggE
87	C0B8K1_9FIRM (C0B8K1)	9e-14	83.2	29%	UniProt GenBank	Putative uncharacterized protein	COPCOM_01475	Coprococcus comes ATCC 27758
88	E8WNW0_GEOS8 (E8WNW0)	9e-14	83.2	28%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	GM18_1287	Geobacter sp. (strain M18)
89	E1QT75_VULDI (E1QT75)	9e-14	83.2	28%	UniProt GenBank	3-hydroxyacyl-CoA dehydrogenase NAD-binding protein	Vdis_0258	Vulcanisaeta distributa (strain DSM 14429 / JCM 11212 / NBRC 100878 / IC-017)
90	Q4KC63_PSEF5 (Q4KC63)	1e-13	82.8	28%	UniProt GenBank	Enoyl-CoA hydratase/isomerase FadB1x	fad-3 PFL_3064	Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
91	CAID_SALTI (Q8Z9L5)	1e-13	82.8	29%	UniProt GenBank	Carnitinyl-CoA dehydratase Crotonobetainyl-CoA hydratase	caiD STY0080 t0071	Salmonella typhi	4.2.1.- niceE keggE
92	D5ZW09_9ACTO (D5ZW09)	1e-13	82.8	37%	UniProt GenBank	Enoyl-CoA hydratase	SSFG_02231	Streptomyces ghanaensis ATCC 14672
93	F8I8I9_9FIRM (F8I8I9)	1e-13	82.8	31%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	paaG TPY_0690	Sulfobacillus acidophilus TPY
94	E7T4B8_SHIBO (E7T4B8)	1e-13	82.8	29%	UniProt GenBank	Phenylacetate degradation enoyl-CoA hydratase PaaA	SGB_04637	Shigella boydii ATCC 9905	4.2.1.17 niceE keggE
95	F8FW64_PSEPU (F8FW64)	1e-13	82.4	29%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	PPS_1829	Pseudomonas putida Arthrobacter siderocapsulatus
96	E9W4J6_ECOLX (E9W4J6)	1e-13	82.4	29%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	ERBG_02453	Escherichia coli E1167
97	E8YAM8_ECOKO (E8YAM8)	2e-13	82.4	29%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	EKO11_2420	Escherichia coli (strain ATCC 55124 / KO11)
98	E0IVR3_ECOLW (E0IVR3)	2e-13	82.4	29%	UniProt GenBank	Enoyl-CoA hydratase-isomerase Enoyl-CoA hydratase/isomerase	paaA ECW_m1527 EschWDRAFT_0058	Escherichia coli (strain ATCC 9637 / CCM 2024 / DSM 1116 / NCIMB 8666 / NRRL B-766 / W)
99	C8U876_ECO10 (C8U876)	2e-13	82.4	29%	UniProt GenBank	Enoyl-CoA hydratase-isomerase	paaF ECO103_1530	Escherichia coli O103:H2 (strain 12009 / EHEC)
100	B7LYN4_ECO8A (B7LYN4)	2e-13	82.4	29%	UniProt GenBank	Enoyl-CoA hydratase-isomerase	paaF ECIAI1_1393	Escherichia coli O8 (strain IAI1)	4.2.1.17 niceE keggE

accession

alignment

Evalue

Score

Ident.

link

information

pubmed

Q6ZZH4_ACTTI
(Q6ZZH4)

0.0

845

100%

Product: DpgC protein
Gene: tcp32
Organism: Actinoplanes teichomyceticus

[pubmed all]
1uniprot[Pubmed] 15113000 Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase.(Chem. Biol.) [2004]
2uniprot[Pubmed] 14702401 Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.(Microbiology) [2004]

E9L1J0_9ZZZZ
(E9L1J0)

0.0

748

88%

Product: Putative uncharacterized protein
Gene: CA37-46
Organism: uncultured organism CA37

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

E9L1U1_9ZZZZ
(E9L1U1)

1e-180

636

79%

Product: Putative uncharacterized protein
Gene: CA915-49
Organism: uncultured organism CA915

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

Q939X1_9PSEU
(Q939X1)

1e-153

545

68%

Product: Hydroxyacyl-dehydrogenase
Gene: dpgC
Organism: Amycolatopsis balhimycina

[pubmed all]
1uniprot[Pubmed] 10390204 [Medline] 99318579 Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908.(Antimicrob. Agents Chemother.) [1999]
2uniprot[Pubmed] 11932455 [Medline] 21930292 Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules.(Microbiology) [2002]
3uniprot[Pubmed] 11495926 [Medline] 21486455 A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.(J. Biol. Chem.) [2001]
4uniprot[Pubmed] 12404385 The biosynthesis of vancomycin-type glycopeptide antibiotics - the order of cyclization steps.(Angew. Chem. Int. Ed. Engl.) [2001]
5uniprot[Pubmed] 11880037 [Medline] 21869276 Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.(Chem. Biol.) [2002]
6uniprot Precursor-directed biosynthesis for the generation of novel glycopetides.(Ernst Schering Res. Found. Workshop) [2005]

O52812_AMYOR
(O52812)

1e-151

539

64%

Product: PCZA361.8
Gene
Organism: Amycolatopsis orientalis
Nocardia orientalis

1uniprot[Pubmed] 9545426 [Medline] 98212597
Sequencing and analysis of genes involved in the biosynthesis of a vancomycin group antibiotic.(Chem. Biol.) [1998]

Q8KLK7_STRTO
(Q8KLK7)

1e-151

539

70%

Product: DpgC
Gene
Organism: Streptomyces toyocaensis

[pubmed all]
1uniprot[Pubmed] 9177243 [Medline] 97322398 D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB.(Proc. Natl. Acad. Sci. U.S.A.) [1997]
2uniprot[Pubmed] 12060705 [Medline] 22080153 Assembling the glycopeptide antibiotic scaffold: the biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009.(Proc. Natl. Acad. Sci. U.S.A.) [2002]
3uniprot[Pubmed] 17507985 Structural basis for cofactor-independent dioxygenation in vancomycin biosynthesis.(Nature) [2007]
4uniprot[Pubmed] 18004875 Substrate recognition and catalysis by the cofactor-independent dioxygenase DpgC.(Biochemistry) [2007]

Q7WZ58_9ACTO
(Q7WZ58)

1e-150

535

67%

Product: Putative DpgC protein
Gene: dbv33
Organism: Nonomuraea sp. ATCC 39727

1uniprot[Pubmed] 12837387 [Medline] 22721464
The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003]

Q2JA69_FRASC
(Q2JA69)

1e-148

528

69%

Product: Enoyl-CoA hydratase/isomerase
Gene: Francci3_2456
Organism: Frankia sp. (strain CcI3)

1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]

B7T1B1_9BACT
(B7T1B1)

1e-145

521

69%

Product: Veg39
Gene: veg39
Organism: uncultured soil bacterium

1uniprot[Pubmed] 18987322
Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008]

E9L1P1_9ZZZZ
(E9L1P1)

1e-145

519

69%

Product: Putative uncharacterized protein
Gene: CA878-42
Organism: uncultured organism CA878

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

E2D2E7_9BACT
(E2D2E7)

1e-143

514

68%

Product: Dihydroxyphenylglycine synthase subunit C
Gene
Organism: uncultured soil bacterium

1uniprot[Pubmed] 20577994
Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.(Biopolymers) [2010]

F2R790_STRVP
(F2R790)

1e-128

462

61%

Product: Enoyl-CoA hydratase or isomerase
Gene: SVEN_0495
Organism: Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)

1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]

D7B4X5_NOCDD
(D7B4X5)

1e-127

460

58%

Product: Enoyl-CoA hydratase/isomerase
Gene: Ndas_1737
Organism: Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei

1uniprot
Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]

F3NRX6_9ACTO
(F3NRX6)

1e-107

393

53%

Product: Putative enoyl-CoA hydratase/isomerase
Gene: SGM_5890
Organism: Streptomyces griseoaurantiacus M045

1uniprot[Pubmed] 21551298
Draft Genome Sequence of the Marine Bacterium Streptomyces griseoaurantiacus M045, Which Produces Novel Manumycin-Type Antibiotics with a pABA Core Component.(J. Bacteriol.) [2011]

D0RB78_STRPR
(D0RB78)

1e-100

371

50%

Product: Hydroxyacyl-dehydrogenase
Putative hydroxyacyl-dehydrogenase
Gene: pglA
Organism: Streptomyces pristinaespiralis

1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]

D2UD62_XANAP
(D2UD62)

5e-98

362

49%

Product: Putative enoyl-coa hydratase isomerase protein
Gene: XALc_1061
Organism: Xanthomonas albilineans (strain GPE PC73 / CFBP 7063)

1uniprot
The complete genome sequence of Xanthomonas albilineans provides new insights into the reductive genome evolution of the xylem-limited Xanthomonadaceae.(BMC Genomics) [2009]

Q9RPT2_9BACT
(Q9RPT2)

2e-59

234

48%

Product: Putative uncharacterized protein
Gene
Organism: uncultured bacterium AH6

1uniprot[Pubmed] 10473393 [Medline] 99402727
Construction of environmental DNA libraries in Escherichia coli and screening for the presence of genes conferring utilization of 4-hydroxybutyrate.(Appl. Environ. Microbiol.) [1999]

E9LIP8_9ACTO
(E9LIP8)

7e-38

163

38%

Product: Putative enoyl-CoA hydratase/isomerase
Gene: tiaN
Organism: Dactylosporangium aurantiacum subsp. hamdenensis

1uniprot[Pubmed] 21186805
Characterization of tiacumicin B biosynthetic gene cluster affording diversified tiacumicin analogues and revealing a tailoring dihalogenase.(J. Am. Chem. Soc.) [2011]

Q8KLK8_STRTO
(Q8KLK8)

1e-17

95.9

32%

Product: DpgD
Gene
Organism: Streptomyces toyocaensis

[pubmed all]
1uniprot[Pubmed] 9177243 [Medline] 97322398 D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB.(Proc. Natl. Acad. Sci. U.S.A.) [1997]
2uniprot[Pubmed] 12060705 [Medline] 22080153 Assembling the glycopeptide antibiotic scaffold: the biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009.(Proc. Natl. Acad. Sci. U.S.A.) [2002]

Q939X0_9PSEU
(Q939X0)

2e-17

95.1

35%

Product: Putative enoyl-CoA-isomerase
Gene: dpgD
Organism: Amycolatopsis balhimycina

[pubmed all]
1uniprot[Pubmed] 10390204 [Medline] 99318579 Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908.(Antimicrob. Agents Chemother.) [1999]
2uniprot[Pubmed] 11932455 [Medline] 21930292 Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules.(Microbiology) [2002]
3uniprot[Pubmed] 11495926 [Medline] 21486455 A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.(J. Biol. Chem.) [2001]
4uniprot[Pubmed] 12404385 The biosynthesis of vancomycin-type glycopeptide antibiotics - the order of cyclization steps.(Angew. Chem. Int. Ed. Engl.) [2001]
5uniprot[Pubmed] 11880037 [Medline] 21869276 Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.(Chem. Biol.) [2002]
6uniprot Precursor-directed biosynthesis for the generation of novel glycopetides.(Ernst Schering Res. Found. Workshop) [2005]

E9L1P2_9ZZZZ
(E9L1P2)

2e-16

34%

Product: Putative uncharacterized protein
Gene: CA878-43
Organism: uncultured organism CA878

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

Q5LPZ0_SILPO
(Q5LPZ0)

2e-16

91.7

31%

Product: Carnitinyl-CoA dehydratase
Gene: caiD-1
SPO2706
Organism: Silicibacter pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)

1uniprot[Pubmed] 15602564
Genome sequence of Silicibacter pomeroyi reveals adaptations to the marine environment.(Nature) [2004]

Q7WZ57_9ACTO
(Q7WZ57)

8e-16

89.7

32%

Product: Putative DpgD protein
Gene: dbv34
Organism: Nonomuraea sp. ATCC 39727

1uniprot[Pubmed] 12837387 [Medline] 22721464
The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003]

D3NY30_AZOS1
(D3NY30)

1e-15

89.4

31%

Product: Enoyl-CoA hydratase
Gene: paaG
AZL_026710
Organism: Azospirillum sp. (strain B510)

1uniprot[Pubmed] 20047946
Complete genomic structure of the cultivated rice endophyte Azospirillum sp. B510.(DNA Res.) [2010]

E2D2E8_9BACT
(E2D2E8)

1e-15

89.4

32%

Product: Dihydroxyphenylglycine synthase subunit D
Gene
Organism: uncultured soil bacterium

1uniprot[Pubmed] 20577994
Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.(Biopolymers) [2010]

Q2N892_ERYLH
(Q2N892)

2e-15

29%

Product: Enoyl-CoA hydratase/isomerase family protein
Gene: ELI_10035
Organism: Erythrobacter litoralis (strain HTCC2594)

1uniprot[Pubmed] 19168610
Complete genome sequence of Erythrobacter litoralis HTCC2594.(J. Bacteriol.) [2009]

Q82Q04_STRAW
(Q82Q04)

4e-15

87.4

33%

Product: Putative enoyl-CoA hydratase
Gene: echA3
SAV717
SAV_717
Organism: Streptomyces avermitilis

1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]

D8F324_9DELT
(D8F324)

6e-15

28%

Product: Enoyl-CoA hydratase/isomerase family protein
Gene: NPH_7275
Organism: delta proteobacterium NaphS2

1uniprot[Pubmed] 21124915
Genome Sequence of the Deltaproteobacterial Strain NaphS2 and Analysis of Differential Gene Expression during Anaerobic Growth on Naphthalene.(PLoS ONE) [2010]

F2LNP5_BURGA
(F2LNP5)

9e-15

86.7

30%

Product: Enoyl-CoA hydratase/isomerase
Gene: bgla_2g20890
Organism: Burkholderia gladioli BSR3

1uniprot[Pubmed] 21478339
Complete Genome Sequence of Burkholderia gladioli BSR3.(J. Bacteriol.) [2011]

C7NG05_KYTSD
(C7NG05)

1e-14

85.9

33%

Product: Short chain enoyl-CoA hydratase
Gene: Ksed_09590
Organism: Kytococcus sedentarius (strain ATCC 14392 / DSM 20547 / CCM 314 / 541)
Micrococcus sedentarius

1uniprot[Pubmed] 21304632
Complete genome sequence of Kytococcus sedentarius type strain (541).(Stand. Genomic Sci.) [2009]

E7DDH9_ALCFA
(E7DDH9)

2e-14

85.5

30%

Product: Enoyl-CoA hydratase family
Gene: acuK
Organism: Alcaligenes faecalis

1uniprot[Pubmed] 21248856
DddY, a periplasmic dimethylsulfoniopropionate lyase found in taxonomically diverse species of Proteobacteria.(ISME J.) [2011]

F4A6J9_CLOBO
(F4A6J9)

5e-14

27%

Product: Enoyl-CoA hydratase/isomerase
Gene: CbC4_2221
Organism: Clostridium botulinum BKT015925

1uniprot[Pubmed] 21486474
Clostridium botulinum group III: a group with dual identity shaped by plasmids, phages and mobile elements.(BMC Genomics) [2011]

F2KGA1_PSEBN
(F2KGA1)

7e-14

83.6

30%

Product: Putative enoyl-CoA hydratase
Gene: PSEBR_a2935
Organism: Pseudomonas brassicacearum (strain NFM421)

1uniprot[Pubmed] 21515771
Complete genome sequence of a beneficial plant root-associated bacterium, Pseudomonas brassicacearum.(J. Bacteriol.) [2011]

E1QT75_VULDI
(E1QT75)

9e-14

83.2

28%

Product: 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein
Gene: Vdis_0258
Organism: Vulcanisaeta distributa (strain DSM 14429 / JCM 11212 / NBRC 100878 / IC-017)

1uniprot
Complete genome sequence of Vulcanisaeta distributa type strain (IC-017T).(Stand. Genomic Sci.) [2010]

Q4KC63_PSEF5
(Q4KC63)

1e-13

82.8

28%

Product: Enoyl-CoA hydratase/isomerase FadB1x
Gene: fad-3
PFL_3064
Organism: Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)

1uniprot[Pubmed] 15980861
Complete genome sequence of the plant commensal Pseudomonas fluorescens Pf-5.(Nat. Biotechnol.) [2005]

CAID_SALTI
(Q8Z9L5)

1e-13

82.8

29%

Product: Carnitinyl-CoA dehydratase
Crotonobetainyl-CoA hydratase
Gene: caiD
STY0080
t0071
Organism: Salmonella typhi

[pubmed all]
1uniprot[Pubmed] 11677608 [Medline] 21534947 Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18.(Nature) [2001]
2uniprot[Pubmed] 12644504 [Medline] 22531367 Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18.(J. Bacteriol.) [2003]

E0IVR3_ECOLW
(E0IVR3)

2e-13

82.4

29%

Product: Enoyl-CoA hydratase-isomerase
Enoyl-CoA hydratase/isomerase
Gene: paaA
ECW_m1527
EschWDRAFT_0058
Organism: Escherichia coli (strain ATCC 9637 / CCM 2024 / DSM 1116 / NCIMB 8666 / NRRL B-766 / W)

1uniprot[Pubmed] 21208457
The genome sequence of E. coli W (ATCC 9637): comparative genome analysis and an improved genome-scale reconstruction of E. coli.(BMC Genomics) [2011]

C8U876_ECO10
(C8U876)

2e-13

82.4

29%

Product: Enoyl-CoA hydratase-isomerase
Gene: paaF
ECO103_1530
Organism: Escherichia coli O103:H2 (strain 12009 / EHEC)

1uniprot[Pubmed] 19815525
Comparative genomics reveal the mechanism of the parallel evolution of O157 and non-O157 enterohemorrhagic Escherichia coli.(Proc. Natl. Acad. Sci. U.S.A.) [2009]

100

B7LYN4_ECO8A
(B7LYN4)

2e-13

82.4

29%

Product: Enoyl-CoA hydratase-isomerase
Gene: paaF
ECIAI1_1393
Organism: Escherichia coli O8 (strain IAI1)

1uniprot[Pubmed] 19165319
Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths.(PLoS Genet.) [2009]