BLAST table : Balhi_00340

DB	UniProtKB

	accession	Evalue	Score	Ident.	link	product	gene	organism	ec
1	Q939X1_9PSEU (Q939X1)	0.0	852	100%	UniProt GenBank	Hydroxyacyl-dehydrogenase	dpgC	Amycolatopsis balhimycina
2	O52812_AMYOR (O52812)	0.0	720	84%	UniProt GenBank	PCZA361.8		Amycolatopsis orientalis Nocardia orientalis
3	Q7WZ58_9ACTO (Q7WZ58)	0.0	697	82%	UniProt GenBank	Putative DpgC protein	dbv33	Nonomuraea sp. ATCC 39727
4	E9L1P1_9ZZZZ (E9L1P1)	0.0	650	86%	UniProt GenBank	Putative uncharacterized protein	CA878-42	uncultured organism CA878
5	B7T1B1_9BACT (B7T1B1)	0.0	649	87%	UniProt GenBank	Veg39	veg39	uncultured soil bacterium
6	F8STZ8_AMYOR (F8STZ8)	1e-180	635	83%	UniProt GenBank	Hydroxyacyl-dehydrogenase	vcm25	Amycolatopsis orientalis Nocardia orientalis
7	E2D2E7_9BACT (E2D2E7)	1e-163	578	72%	UniProt GenBank	Dihydroxyphenylglycine synthase subunit C		uncultured soil bacterium
8	Q8KLK7_STRTO (Q8KLK7)	1e-162	576	73%	UniProt GenBank	DpgC		Streptomyces toyocaensis
9	E9L1J0_9ZZZZ (E9L1J0)	1e-157	561	67%	UniProt GenBank	Putative uncharacterized protein	CA37-46	uncultured organism CA37
10	Q2JA69_FRASC (Q2JA69)	1e-156	556	70%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Francci3_2456	Frankia sp. (strain CcI3)
11	E9L1U1_9ZZZZ (E9L1U1)	1e-150	536	66%	UniProt GenBank	Putative uncharacterized protein	CA915-49	uncultured organism CA915
12	Q6ZZH4_ACTTI (Q6ZZH4)	1e-150	536	68%	UniProt GenBank	DpgC protein	tcp32	Actinoplanes teichomyceticus
13	F2R790_STRVP (F2R790)	1e-133	479	58%	UniProt GenBank	Enoyl-CoA hydratase or isomerase	SVEN_0495	Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
14	D7B4X5_NOCDD (D7B4X5)	1e-133	478	60%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Ndas_1737	Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei
15	D9UHH7_9ACTO (D9UHH7)	1e-130	471	60%	UniProt GenBank	Hydroxyacyl-dehydrogenase	SSLG_05413	Streptomyces sp. SPB78
16	C0Z469_STRVN (C0Z469)	1e-121	440	56%	UniProt GenBank	Dioxygenase	ken4	Streptomyces violaceoruber
17	F3ZDK5_9ACTO (F3ZDK5)	1e-114	415	64%	UniProt GenBank	Putative enoyl-CoA hydratase/isomerase	STTU_1158	Streptomyces sp. Tu6071
18	F3NRX6_9ACTO (F3NRX6)	1e-106	390	51%	UniProt GenBank	Putative enoyl-CoA hydratase/isomerase	SGM_5890	Streptomyces griseoaurantiacus M045
19	D2UD62_XANAP (D2UD62)	1e-106	390	51%	UniProt GenBank	Putative enoyl-coa hydratase isomerase protein	XALc_1061	Xanthomonas albilineans (strain GPE PC73 / CFBP 7063)
20	D6A5M8_9ACTO (D6A5M8)	1e-103	380	51%	UniProt GenBank	DpgC protein	SSFG_06976	Streptomyces ghanaensis ATCC 14672
21	D2PSN9_KRIFD (D2PSN9)	1e-100	370	56%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Kfla_4130	Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)
22	D0RB78_STRPR (D0RB78)	6e-99	365	48%	UniProt GenBank	Hydroxyacyl-dehydrogenase Putative hydroxyacyl-dehydrogenase	pglA	Streptomyces pristinaespiralis
23	B5HJU2_STRPR (B5HJU2)	6e-99	365	48%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	SSDG_05431	Streptomyces pristinaespiralis ATCC 25486
24	Q9RPT2_9BACT (Q9RPT2)	3e-60	237	47%	UniProt GenBank	Putative uncharacterized protein		uncultured bacterium AH6
25	E9LIP8_9ACTO (E9LIP8)	6e-37	160	36%	UniProt GenBank	Putative enoyl-CoA hydratase/isomerase	tiaN	Dactylosporangium aurantiacum subsp. hamdenensis
26	Q1NB15_9SPHN (Q1NB15)	2e-20	105	34%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	SKA58_07548	Sphingomonas sp. SKA58
27	D4Z2S5_SPHJU (D4Z2S5)	3e-20	104	34%	UniProt GenBank	Enoyl-CoA hydratase	paaG SJA_C1-20730	Sphingobium japonicum (strain NBRC 101211 / UT26S)	4.2.1.17 niceE keggE
28	F6EUP7_SPHCR (F6EUP7)	5e-20	103	34%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Sphch_1075	Sphingobium chlorophenolicum L-1
29	Q939X0_9PSEU (Q939X0)	1e-19	102	38%	UniProt GenBank	Putative enoyl-CoA-isomerase	dpgD	Amycolatopsis balhimycina
30	E9L1P2_9ZZZZ (E9L1P2)	2e-19	101	37%	UniProt GenBank	Putative uncharacterized protein	CA878-43	uncultured organism CA878
31	A5PAX2_9SPHN (A5PAX2)	5e-18	97.1	32%	UniProt GenBank	Enoyl-CoA hydratase/isomerase family protein	ED21_21894	Erythrobacter sp. SD-21
32	F6INA6_9SPHN (F6INA6)	2e-17	95.5	31%	UniProt GenBank	Enoyl-CoA hydratase	PP1Y_AT20327	Novosphingobium sp. PP1Y	4.2.1.17 niceE keggE
33	F8I8I9_9FIRM (F8I8I9)	4e-17	94.4	34%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	paaG TPY_0690	Sulfobacillus acidophilus TPY
34	E2D2E8_9BACT (E2D2E8)	4e-17	94	35%	UniProt GenBank	Dihydroxyphenylglycine synthase subunit D		uncultured soil bacterium
35	F2R778_STRVP (F2R778)	5e-17	94	36%	UniProt GenBank	Enoyl-CoA hydratase	SVEN_0483	Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)	4.2.1.17 niceE keggE
36	A7IKJ4_XANP2 (A7IKJ4)	1e-16	92.8	32%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Xaut_3308	Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)
37	A8N3H3_COPC7 (A8N3H3)	1e-16	92.4	33%	UniProt GenBank	Enoyl-CoA hydratase/carnithine racemase	CC1G_00729	Coprinopsis cinerea (strain Okayama-7 / 130 / FGSC 9003) Inky cap fungus Hormographiella aspergillata
38	Q2N892_ERYLH (Q2N892)	2e-16	92.4	32%	UniProt GenBank	Enoyl-CoA hydratase/isomerase family protein	ELI_10035	Erythrobacter litoralis (strain HTCC2594)
39	Q2GA18_NOVAD (Q2GA18)	2e-16	91.7	32%	UniProt GenBank	Short chain enoyl-CoA hydratase	Saro_0860	Novosphingobium aromaticivorans (strain DSM 12444)	4.2.1.17 niceE keggE
40	Q8KLK8_STRTO (Q8KLK8)	4e-16	90.9	34%	UniProt GenBank	DpgD		Streptomyces toyocaensis
41	F8STZ9_AMYOR (F8STZ9)	4e-16	90.9	35%	UniProt GenBank	Enoyl-CoA hydratase	vcm26	Amycolatopsis orientalis Nocardia orientalis
42	A3WEF3_9SPHN (A3WEF3)	5e-16	90.5	31%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	NAP1_10393	Erythrobacter sp. NAP1
43	Q7WZ57_9ACTO (Q7WZ57)	7e-16	90.1	35%	UniProt GenBank	Putative DpgD protein	dbv34	Nonomuraea sp. ATCC 39727
44	D8F324_9DELT (D8F324)	9e-16	89.7	31%	UniProt GenBank	Enoyl-CoA hydratase/isomerase family protein	NPH_7275	delta proteobacterium NaphS2
45	F8E8W7_FLESI (F8E8W7)	1e-15	89.7	30%	UniProt GenBank	3-hydroxybutyryl-CoA dehydratase	Flexsi_0403	Flexistipes sinusarabici	4.2.1.55 niceE keggE
46	E8WNW0_GEOS8 (E8WNW0)	1e-15	89.4	31%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	GM18_1287	Geobacter sp. (strain M18)
47	Q64BG5_9ARCH (Q64BG5)	1e-15	89.4	30%	UniProt GenBank	Enoyl-CoA hydratase/carnithine racemase	GZ27B6_24	uncultured archaeon GZfos27B6
48	F6XMQ1_MONDO (F6XMQ1)	1e-15	89.4	31%	UniProt GenBank	Uncharacterized protein	ECHDC2	Monodelphis domestica Gray short-tailed gray opossum
49	A4X476_SALTO (A4X476)	2e-15	89	34%	UniProt GenBank	Short chain enoyl-CoA hydratase	Strop_1206	Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)	4.2.1.17 niceE keggE
50	E8L2H2_9RHIZ (E8L2H2)	2e-15	89	32%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Met49242DRAFT_1713	Methylocystis sp. ATCC 49242
51	B9CYZ5_WOLRE (B9CYZ5)	2e-15	88.6	32%	UniProt GenBank	3-hydroxybutyryl-CoA dehydratase (Crotonase)	CAMRE0001_1568	Campylobacter rectus RM3267	4.2.1.55 niceE keggE
52	E0TEI9_PARBH (E0TEI9)	2e-15	88.6	32%	UniProt GenBank	Enoyl CoA hydratase	PB2503_12094	Parvularcula bermudensis (strain ATCC BAA-594 / HTCC2503 / KCTC 12087)
53	F0L542_AGRSH (F0L542)	2e-15	88.6	31%	UniProt GenBank	Enoyl-CoA hydratase	fadB AGROH133_03485	Agrobacterium sp. (strain H13-3) Rhizobium lupini (strain H13-3)	4.2.1.17 niceE keggE
54	F1Z4G9_9SPHN (F1Z4G9)	2e-15	88.2	31%	UniProt GenBank	Short chain enoyl-CoA hydratase	Y88_2869	Novosphingobium nitrogenifigens DSM 19370
55	D9UHI4_9ACTO (D9UHI4)	2e-15	88.2	34%	UniProt GenBank	2-ketocyclohexanecarboxyl-CoA hydrolase	SSLG_05420	Streptomyces sp. SPB78
56	E7C8P6_9GAMM (E7C8P6)	3e-15	88.2	31%	UniProt GenBank	Enoyl-CoA hydratase/carnithine racemase		uncultured gamma proteobacterium HF4000_47G05
57	O52797_AMYOR (O52797)	3e-15	88.2	35%	UniProt GenBank	PCZA361.9		Amycolatopsis orientalis Nocardia orientalis
58	F3ZDK0_9ACTO (F3ZDK0)	3e-15	87.8	33%	UniProt GenBank	Putative enoyl-CoA hydratase	STTU_1153	Streptomyces sp. Tu6071
59	A5V769_SPHWW (A5V769)	3e-15	87.8	33%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Swit_1773	Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)
60	Q1LK46_RALME (Q1LK46)	4e-15	87.4	34%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	paaG1 Rmet_2603	Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)	4.2.1.17 niceE keggE
61	B7T1B2_9BACT (B7T1B2)	4e-15	87.4	35%	UniProt GenBank	Veg40	veg40	uncultured soil bacterium
62	E3BB41_9MICO (E3BB41)	4e-15	87.4	32%	UniProt GenBank	3-hydroxybutyryl-CoA dehydratase	crt HMPREF0321_2790	Dermacoccus sp. Ellin185	4.2.1.55 niceE keggE
63	Q2NDF3_ERYLH (Q2NDF3)	5e-15	87.4	32%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	ELI_00980	Erythrobacter litoralis (strain HTCC2594)
64	F7U4B4_RHIRD (F7U4B4)	5e-15	87.4	31%	UniProt GenBank	Enoyl-CoA hydratase	paaG Agau_C101513	Agrobacterium tumefaciens F2
65	A4FKR8_SACEN (A4FKR8)	5e-15	87.4	36%	UniProt GenBank	Enoyl-CoA hydratase/carnithine racemase	SACE_5406	Saccharopolyspora erythraea (strain NRRL 23338)	4.2.1.17 niceE keggE
66	C0Z466_STRVN (C0Z466)	6e-15	87	36%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	ken7	Streptomyces violaceoruber
67	Q582Q0_9TRYP (Q582Q0)	8e-15	86.7	34%	UniProt GenBank	Enoyl-CoA hydratase, mitochondrial, putative	Tb927.3.4850	Trypanosoma brucei	4.2.1.17 niceE keggE
68	D6XE41_TRYB2 (D6XE41)	8e-15	86.7	34%	UniProt GenBank	Enoyl-CoA hydratase, mitochondrial, putative	Tb927.3.4850	Trypanosoma brucei brucei (strain 927/4 GUTat10.1)	4.2.1.17 niceE keggE
69	C9ZLJ2_TRYB9 (C9ZLJ2)	8e-15	86.7	34%	UniProt GenBank	Enoyl-CoA hydratase, mitochondrial,putative	TbgDal_III5430	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	4.2.1.17 niceE keggE
70	F4F9C2_VERMA (F4F9C2)	9e-15	86.7	35%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	VAB18032_10990	Verrucosispora maris (strain AB-18-032)
71	D3NY30_AZOS1 (D3NY30)	9e-15	86.3	33%	UniProt GenBank	Enoyl-CoA hydratase	paaG AZL_026710	Azospirillum sp. (strain B510)	4.2.1.17 niceE keggE
72	F4A6J9_CLOBO (F4A6J9)	9e-15	86.3	31%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	CbC4_2221	Clostridium botulinum BKT015925	4.2.1.55 niceE keggE
73	Q1GNL3_SPHAL (Q1GNL3)	1e-14	86.3	32%	UniProt GenBank	Short chain enoyl-CoA hydratase	Sala_3055	Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256) Sphingomonas alaskensis	4.2.1.17 niceE keggE
74	A8IQN3_AZOC5 (A8IQN3)	1e-14	86.3	33%	UniProt GenBank	Enoyl-CoA hydratase	AZC_0802	Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571)
75	C8WPU8_EGGLE (C8WPU8)	1e-14	86.3	32%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Elen_3100	Eggerthella lenta (strain ATCC 25559 / DSM 2243 / JCM 9979 / NCTC 11813 / VPI 0255) Eubacterium lentum
76	F7MNE5_CLOBO (F7MNE5)	1e-14	85.9	31%	UniProt GenBank	3-hydroxybutyryl-CoA dehydratase	CBCST_10366	Clostridium botulinum C str. Stockholm	4.2.1.55 niceE keggE
77	D3D8V1_9ACTO (D3D8V1)	1e-14	85.9	33%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	FrEUN1fDRAFT_6223	Frankia sp. EUN1f
78	A3K328_9RHOB (A3K328)	1e-14	85.9	30%	UniProt GenBank	Enoyl-CoA hydratase	SSE37_17283	Sagittula stellata E-37
79	C5VNX5_CLOBO (C5VNX5)	1e-14	85.9	31%	UniProt GenBank	3-hydroxybutyryl-CoA dehydratase	CLG_B0355	Clostridium botulinum D str. 1873	4.2.1.55 niceE keggE
80	E7DDH9_ALCFA (E7DDH9)	1e-14	85.9	32%	UniProt GenBank	Enoyl-CoA hydratase family	acuK	Alcaligenes faecalis
81	A8M5D3_SALAI (A8M5D3)	1e-14	85.5	34%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Sare_1099	Salinispora arenicola (strain CNS-205)
82	E6JBY1_9ACTO (E6JBY1)	2e-14	85.5	33%	UniProt GenBank	Enoyl-CoA hydratase	ES5_13735	Dietzia cinnamea P4
83	F2KGA1_PSEBN (F2KGA1)	2e-14	85.5	31%	UniProt GenBank	Putative enoyl-CoA hydratase	PSEBR_a2935	Pseudomonas brassicacearum (strain NFM421)
84	A0QFV0_MYCA1 (A0QFV0)	2e-14	85.5	31%	UniProt GenBank	Carnitinyl-CoA dehydratase	MAV_2597	Mycobacterium avium (strain 104)	4.2.1.- niceE keggE
85	A8U121_9PROT (A8U121)	2e-14	85.5	33%	UniProt GenBank	Probable enoyl-CoA hydratase	BAL199_10180	alpha proteobacterium BAL199
86	B1JBL8_PSEPW (B1JBL8)	2e-14	85.5	33%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	PputW619_3454	Pseudomonas putida (strain W619)
87	D7B4X4_NOCDD (D7B4X4)	2e-14	85.1	34%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	Ndas_1736	Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei
88	C1B644_RHOOB (C1B644)	2e-14	85.1	32%	UniProt GenBank	Enoyl-CoA hydratase	echA ROP_72080	Rhodococcus opacus (strain B4)	4.2.1.17 niceE keggE
89	E7C834_9GAMM (E7C834)	2e-14	85.1	33%	UniProt GenBank	Enoyl-CoA hydratase/carnithine racemase		uncultured gamma proteobacterium HF4000_06A21
90	A5V798_SPHWW (A5V798)	2e-14	85.1	32%	UniProt GenBank	Short chain enoyl-CoA hydratase	Swit_1803	Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)	4.2.1.17 niceE keggE
91	A5V400_SPHWW (A5V400)	2e-14	85.1	32%	UniProt GenBank	Short chain enoyl-CoA hydratase	Swit_0648	Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)	4.2.1.17 niceE keggE
92	B0DW44_LACBS (B0DW44)	2e-14	85.1	31%	UniProt GenBank	Enoyl-CoA hydratase	ECH-1 LACBIDRAFT_312422	Laccaria bicolor (strain S238N-H82) Bicoloured deceiver Laccaria laccata var. bicolor
93	E7C4A8_9ACTN (E7C4A8)	2e-14	85.1	27%	UniProt GenBank	Enoyl-CoA hydratase/carnithine racemase		uncultured actinobacterium HF0200_46I24
94	E7C432_9GAMM (E7C432)	2e-14	85.1	27%	UniProt GenBank	Enoyl-CoA hydratase/carnithine racemase		uncultured gamma proteobacterium HF0200_34B07
95	F2LNP5_BURGA (F2LNP5)	2e-14	85.1	32%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	bgla_2g20890	Burkholderia gladioli BSR3
96	B1FHT4_9BURK (B1FHT4)	3e-14	85.1	33%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	BamIOP4010DRAFT_3594	Burkholderia ambifaria IOP40-10
97	C4LH94_CORK4 (C4LH94)	3e-14	84.7	33%	UniProt GenBank	Enoyl-CoA hydratase	echA1 ckrop_0420	Corynebacterium kroppenstedtii (strain DSM 44385 / CCUG 35717)	4.2.1.17 niceE keggE
98	Q2RMQ0_RHORT (Q2RMQ0)	3e-14	84.7	32%	UniProt GenBank	Short chain enoyl-CoA hydratase	Rru_A3801	Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)	4.2.1.17 niceE keggE
99	E1IGB5_9CHLR (E1IGB5)	3e-14	84.7	31%	UniProt GenBank	Enoyl-CoA hydratase/isomerase	OSCT_2366	Oscillochloris trichoides DG-6
100	F1YJ06_9ACTO (F1YJ06)	3e-14	84.7	35%	UniProt GenBank	Putative enoyl-CoA hydratase/isomerase family protein	SCNU_09346	Gordonia neofelifaecis NRRL B-59395

accession

alignment

Evalue

Score

Ident.

link

information

pubmed

Q939X1_9PSEU
(Q939X1)

0.0

852

100%

Product: Hydroxyacyl-dehydrogenase
Gene: dpgC
Organism: Amycolatopsis balhimycina

[pubmed all]
1uniprot[Pubmed] 10390204 [Medline] 99318579 Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908.(Antimicrob. Agents Chemother.) [1999]
2uniprot[Pubmed] 11932455 [Medline] 21930292 Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules.(Microbiology) [2002]
3uniprot[Pubmed] 11495926 [Medline] 21486455 A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.(J. Biol. Chem.) [2001]
4uniprot[Pubmed] 12404385 The biosynthesis of vancomycin-type glycopeptide antibiotics - the order of cyclization steps.(Angew. Chem. Int. Ed. Engl.) [2001]
5uniprot[Pubmed] 11880037 [Medline] 21869276 Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.(Chem. Biol.) [2002]
6uniprot Precursor-directed biosynthesis for the generation of novel glycopetides.(Ernst Schering Res. Found. Workshop) [2005]

O52812_AMYOR
(O52812)

0.0

720

84%

Product: PCZA361.8
Gene
Organism: Amycolatopsis orientalis
Nocardia orientalis

1uniprot[Pubmed] 9545426 [Medline] 98212597
Sequencing and analysis of genes involved in the biosynthesis of a vancomycin group antibiotic.(Chem. Biol.) [1998]

Q7WZ58_9ACTO
(Q7WZ58)

0.0

697

82%

Product: Putative DpgC protein
Gene: dbv33
Organism: Nonomuraea sp. ATCC 39727

1uniprot[Pubmed] 12837387 [Medline] 22721464
The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003]

E9L1P1_9ZZZZ
(E9L1P1)

0.0

650

86%

Product: Putative uncharacterized protein
Gene: CA878-42
Organism: uncultured organism CA878

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

B7T1B1_9BACT
(B7T1B1)

0.0

649

87%

Product: Veg39
Gene: veg39
Organism: uncultured soil bacterium

1uniprot[Pubmed] 18987322
Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008]

E2D2E7_9BACT
(E2D2E7)

1e-163

578

72%

Product: Dihydroxyphenylglycine synthase subunit C
Gene
Organism: uncultured soil bacterium

1uniprot[Pubmed] 20577994
Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.(Biopolymers) [2010]

Q8KLK7_STRTO
(Q8KLK7)

1e-162

576

73%

Product: DpgC
Gene
Organism: Streptomyces toyocaensis

[pubmed all]
1uniprot[Pubmed] 9177243 [Medline] 97322398 D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB.(Proc. Natl. Acad. Sci. U.S.A.) [1997]
2uniprot[Pubmed] 12060705 [Medline] 22080153 Assembling the glycopeptide antibiotic scaffold: the biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009.(Proc. Natl. Acad. Sci. U.S.A.) [2002]
3uniprot[Pubmed] 17507985 Structural basis for cofactor-independent dioxygenation in vancomycin biosynthesis.(Nature) [2007]
4uniprot[Pubmed] 18004875 Substrate recognition and catalysis by the cofactor-independent dioxygenase DpgC.(Biochemistry) [2007]

E9L1J0_9ZZZZ
(E9L1J0)

1e-157

561

67%

Product: Putative uncharacterized protein
Gene: CA37-46
Organism: uncultured organism CA37

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

Q2JA69_FRASC
(Q2JA69)

1e-156

556

70%

Product: Enoyl-CoA hydratase/isomerase
Gene: Francci3_2456
Organism: Frankia sp. (strain CcI3)

1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]

E9L1U1_9ZZZZ
(E9L1U1)

1e-150

536

66%

Product: Putative uncharacterized protein
Gene: CA915-49
Organism: uncultured organism CA915

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

Q6ZZH4_ACTTI
(Q6ZZH4)

1e-150

536

68%

Product: DpgC protein
Gene: tcp32
Organism: Actinoplanes teichomyceticus

[pubmed all]
1uniprot[Pubmed] 15113000 Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase.(Chem. Biol.) [2004]
2uniprot[Pubmed] 14702401 Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.(Microbiology) [2004]

F2R790_STRVP
(F2R790)

1e-133

479

58%

Product: Enoyl-CoA hydratase or isomerase
Gene: SVEN_0495
Organism: Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)

1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]

D7B4X5_NOCDD
(D7B4X5)

1e-133

478

60%

Product: Enoyl-CoA hydratase/isomerase
Gene: Ndas_1737
Organism: Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei

1uniprot
Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]

F3NRX6_9ACTO
(F3NRX6)

1e-106

390

51%

Product: Putative enoyl-CoA hydratase/isomerase
Gene: SGM_5890
Organism: Streptomyces griseoaurantiacus M045

1uniprot[Pubmed] 21551298
Draft Genome Sequence of the Marine Bacterium Streptomyces griseoaurantiacus M045, Which Produces Novel Manumycin-Type Antibiotics with a pABA Core Component.(J. Bacteriol.) [2011]

D2UD62_XANAP
(D2UD62)

1e-106

390

51%

Product: Putative enoyl-coa hydratase isomerase protein
Gene: XALc_1061
Organism: Xanthomonas albilineans (strain GPE PC73 / CFBP 7063)

1uniprot
The complete genome sequence of Xanthomonas albilineans provides new insights into the reductive genome evolution of the xylem-limited Xanthomonadaceae.(BMC Genomics) [2009]

D0RB78_STRPR
(D0RB78)

6e-99

365

48%

Product: Hydroxyacyl-dehydrogenase
Putative hydroxyacyl-dehydrogenase
Gene: pglA
Organism: Streptomyces pristinaespiralis

1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]

Q9RPT2_9BACT
(Q9RPT2)

3e-60

237

47%

Product: Putative uncharacterized protein
Gene
Organism: uncultured bacterium AH6

1uniprot[Pubmed] 10473393 [Medline] 99402727
Construction of environmental DNA libraries in Escherichia coli and screening for the presence of genes conferring utilization of 4-hydroxybutyrate.(Appl. Environ. Microbiol.) [1999]

E9LIP8_9ACTO
(E9LIP8)

6e-37

160

36%

Product: Putative enoyl-CoA hydratase/isomerase
Gene: tiaN
Organism: Dactylosporangium aurantiacum subsp. hamdenensis

1uniprot[Pubmed] 21186805
Characterization of tiacumicin B biosynthetic gene cluster affording diversified tiacumicin analogues and revealing a tailoring dihalogenase.(J. Am. Chem. Soc.) [2011]

Q939X0_9PSEU
(Q939X0)

1e-19

102

38%

Product: Putative enoyl-CoA-isomerase
Gene: dpgD
Organism: Amycolatopsis balhimycina

[pubmed all]
1uniprot[Pubmed] 10390204 [Medline] 99318579 Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908.(Antimicrob. Agents Chemother.) [1999]
2uniprot[Pubmed] 11932455 [Medline] 21930292 Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules.(Microbiology) [2002]
3uniprot[Pubmed] 11495926 [Medline] 21486455 A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.(J. Biol. Chem.) [2001]
4uniprot[Pubmed] 12404385 The biosynthesis of vancomycin-type glycopeptide antibiotics - the order of cyclization steps.(Angew. Chem. Int. Ed. Engl.) [2001]
5uniprot[Pubmed] 11880037 [Medline] 21869276 Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.(Chem. Biol.) [2002]
6uniprot Precursor-directed biosynthesis for the generation of novel glycopetides.(Ernst Schering Res. Found. Workshop) [2005]

E9L1P2_9ZZZZ
(E9L1P2)

2e-19

101

37%

Product: Putative uncharacterized protein
Gene: CA878-43
Organism: uncultured organism CA878

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

E2D2E8_9BACT
(E2D2E8)

4e-17

35%

Product: Dihydroxyphenylglycine synthase subunit D
Gene
Organism: uncultured soil bacterium

1uniprot[Pubmed] 20577994
Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.(Biopolymers) [2010]

F2R778_STRVP
(F2R778)

5e-17

36%

Product: Enoyl-CoA hydratase
Gene: SVEN_0483
Organism: Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)

1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]

A8N3H3_COPC7
(A8N3H3)

1e-16

92.4

33%

Product: Enoyl-CoA hydratase/carnithine racemase
Gene: CC1G_00729
Organism: Coprinopsis cinerea (strain Okayama-7 / 130 / FGSC 9003)
Inky cap fungus
Hormographiella aspergillata

1uniprot[Pubmed] 20547848
Insights into evolution of multicellular fungi from the assembled chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus).(Proc. Natl. Acad. Sci. U.S.A.) [2010]

Q2N892_ERYLH
(Q2N892)

2e-16

92.4

32%

Product: Enoyl-CoA hydratase/isomerase family protein
Gene: ELI_10035
Organism: Erythrobacter litoralis (strain HTCC2594)

1uniprot[Pubmed] 19168610
Complete genome sequence of Erythrobacter litoralis HTCC2594.(J. Bacteriol.) [2009]

Q8KLK8_STRTO
(Q8KLK8)

4e-16

90.9

34%

Product: DpgD
Gene
Organism: Streptomyces toyocaensis

[pubmed all]
1uniprot[Pubmed] 9177243 [Medline] 97322398 D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB.(Proc. Natl. Acad. Sci. U.S.A.) [1997]
2uniprot[Pubmed] 12060705 [Medline] 22080153 Assembling the glycopeptide antibiotic scaffold: the biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009.(Proc. Natl. Acad. Sci. U.S.A.) [2002]

Q7WZ57_9ACTO
(Q7WZ57)

7e-16

90.1

35%

Product: Putative DpgD protein
Gene: dbv34
Organism: Nonomuraea sp. ATCC 39727

1uniprot[Pubmed] 12837387 [Medline] 22721464
The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003]

D8F324_9DELT
(D8F324)

9e-16

89.7

31%

Product: Enoyl-CoA hydratase/isomerase family protein
Gene: NPH_7275
Organism: delta proteobacterium NaphS2

1uniprot[Pubmed] 21124915
Genome Sequence of the Deltaproteobacterial Strain NaphS2 and Analysis of Differential Gene Expression during Anaerobic Growth on Naphthalene.(PLoS ONE) [2010]

Q64BG5_9ARCH
(Q64BG5)

1e-15

89.4

30%

Product: Enoyl-CoA hydratase/carnithine racemase
Gene: GZ27B6_24
Organism: uncultured archaeon GZfos27B6

1uniprot[Pubmed] 15353801
Reverse methanogenesis: testing the hypothesis with environmental genomics.(Science) [2004]

F6XMQ1_MONDO
(F6XMQ1)

1e-15

89.4

31%

Product: Uncharacterized protein
Gene: ECHDC2
Organism: Monodelphis domestica
Gray short-tailed gray opossum

1uniprot[Pubmed] 17495919
Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences.(Nature) [2007]

E8L2H2_9RHIZ
(E8L2H2)

2e-15

32%

Product: Enoyl-CoA hydratase/isomerase
Gene: Met49242DRAFT_1713
Organism: Methylocystis sp. ATCC 49242

1uniprot[Pubmed] 21441518
Genome Sequence of the Methanotrophic Alphaproteobacterium Methylocystis sp. Strain Rockwell (ATCC 49242).(J. Bacteriol.) [2011]

F0L542_AGRSH
(F0L542)

2e-15

88.6

31%

Product: Enoyl-CoA hydratase
Gene: fadB
AGROH133_03485
Organism: Agrobacterium sp. (strain H13-3)
Rhizobium lupini (strain H13-3)

1uniprot[Pubmed] 21329740
Complete genome sequencing of Agrobacterium sp H13-3, the former Rhizobium lupini H13-3, reveals a tripartite genome consisting of a circular and a linear chromosome and an accessory plasmid but lacking a tumor-inducing Ti-plasmid.(J. Biotechnol.) [2011]

O52797_AMYOR
(O52797)

3e-15

88.2

35%

Product: PCZA361.9
Gene
Organism: Amycolatopsis orientalis
Nocardia orientalis

1uniprot[Pubmed] 9545426 [Medline] 98212597
Sequencing and analysis of genes involved in the biosynthesis of a vancomycin group antibiotic.(Chem. Biol.) [1998]

B7T1B2_9BACT
(B7T1B2)

4e-15

87.4

35%

Product: Veg40
Gene: veg40
Organism: uncultured soil bacterium

1uniprot[Pubmed] 18987322
Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008]

Q2NDF3_ERYLH
(Q2NDF3)

5e-15

87.4

32%

Product: Enoyl-CoA hydratase/isomerase
Gene: ELI_00980
Organism: Erythrobacter litoralis (strain HTCC2594)

1uniprot[Pubmed] 19168610
Complete genome sequence of Erythrobacter litoralis HTCC2594.(J. Bacteriol.) [2009]

A4FKR8_SACEN
(A4FKR8)

5e-15

87.4

36%

Product: Enoyl-CoA hydratase/carnithine racemase
Gene: SACE_5406
Organism: Saccharopolyspora erythraea (strain NRRL 23338)

1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]

D6XE41_TRYB2
(D6XE41)

8e-15

86.7

34%

Product: Enoyl-CoA hydratase, mitochondrial, putative
Gene: Tb927.3.4850
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)

[pubmed all]
1uniprot[Pubmed] 16020724 Comparative genomics of trypanosomatid parasitic protozoa.(Science) [2005]
2uniprot[Pubmed] 16020726 The genome of the African trypanosome Trypanosoma brucei.(Science) [2005]

C9ZLJ2_TRYB9
(C9ZLJ2)

8e-15

86.7

34%

Product: Enoyl-CoA hydratase, mitochondrial,putative
Gene: TbgDal_III5430
Organism: Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)

1uniprot[Pubmed] 20404998
The genome sequence of Trypanosoma brucei gambiense, causative agent of chronic human african trypanosomiasis.(PLoS Negl. Trop. Dis.) [2010]

F4F9C2_VERMA
(F4F9C2)

9e-15

86.7

35%

Product: Enoyl-CoA hydratase/isomerase
Gene: VAB18032_10990
Organism: Verrucosispora maris (strain AB-18-032)

1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]

D3NY30_AZOS1
(D3NY30)

9e-15

86.3

33%

Product: Enoyl-CoA hydratase
Gene: paaG
AZL_026710
Organism: Azospirillum sp. (strain B510)

1uniprot[Pubmed] 20047946
Complete genomic structure of the cultivated rice endophyte Azospirillum sp. B510.(DNA Res.) [2010]

F4A6J9_CLOBO
(F4A6J9)

9e-15

86.3

31%

Product: Enoyl-CoA hydratase/isomerase
Gene: CbC4_2221
Organism: Clostridium botulinum BKT015925

1uniprot[Pubmed] 21486474
Clostridium botulinum group III: a group with dual identity shaped by plasmids, phages and mobile elements.(BMC Genomics) [2011]

C8WPU8_EGGLE
(C8WPU8)

1e-14

86.3

32%

Product: Enoyl-CoA hydratase/isomerase
Gene: Elen_3100
Organism: Eggerthella lenta (strain ATCC 25559 / DSM 2243 / JCM 9979 / NCTC 11813 / VPI 0255)
Eubacterium lentum

1uniprot[Pubmed] 21304654
Complete genome sequence of Eggerthella lenta type strain (IPP VPI 0255).(Stand. Genomic Sci.) [2009]

F7MNE5_CLOBO
(F7MNE5)

1e-14

85.9

31%

Product: 3-hydroxybutyryl-CoA dehydratase
Gene: CBCST_10366
Organism: Clostridium botulinum C str. Stockholm

1uniprot[Pubmed] 21486474
Clostridium botulinum group III: a group with dual identity shaped by plasmids, phages and mobile elements.(BMC Genomics) [2011]

E7DDH9_ALCFA
(E7DDH9)

1e-14

85.9

32%

Product: Enoyl-CoA hydratase family
Gene: acuK
Organism: Alcaligenes faecalis

1uniprot[Pubmed] 21248856
DddY, a periplasmic dimethylsulfoniopropionate lyase found in taxonomically diverse species of Proteobacteria.(ISME J.) [2011]

F2KGA1_PSEBN
(F2KGA1)

2e-14

85.5

31%

Product: Putative enoyl-CoA hydratase
Gene: PSEBR_a2935
Organism: Pseudomonas brassicacearum (strain NFM421)

1uniprot[Pubmed] 21515771
Complete genome sequence of a beneficial plant root-associated bacterium, Pseudomonas brassicacearum.(J. Bacteriol.) [2011]

D7B4X4_NOCDD
(D7B4X4)

2e-14

85.1

34%

Product: Enoyl-CoA hydratase/isomerase
Gene: Ndas_1736
Organism: Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei

1uniprot
Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]

B0DW44_LACBS
(B0DW44)

2e-14

85.1

31%

Product: Enoyl-CoA hydratase
Gene: ECH-1
LACBIDRAFT_312422
Organism: Laccaria bicolor (strain S238N-H82)
Bicoloured deceiver
Laccaria laccata var. bicolor

1uniprot[Pubmed] 18322534
The genome of Laccaria bicolor provides insights into mycorrhizal symbiosis.(Nature) [2008]

F2LNP5_BURGA
(F2LNP5)

2e-14

85.1

32%

Product: Enoyl-CoA hydratase/isomerase
Gene: bgla_2g20890
Organism: Burkholderia gladioli BSR3

1uniprot[Pubmed] 21478339
Complete Genome Sequence of Burkholderia gladioli BSR3.(J. Bacteriol.) [2011]

C4LH94_CORK4
(C4LH94)

3e-14

84.7

33%

Product: Enoyl-CoA hydratase
Gene: echA1
ckrop_0420
Organism: Corynebacterium kroppenstedtii (strain DSM 44385 / CCUG 35717)

1uniprot[Pubmed] 18430482
Ultrafast pyrosequencing of Corynebacterium kroppenstedtii DSM44385 revealed insights into the physiology of a lipophilic corynebacterium that lacks mycolic acids.(J. Biotechnol.) [2008]

E1IGB5_9CHLR
(E1IGB5)

3e-14

84.7

31%

Product: Enoyl-CoA hydratase/isomerase
Gene: OSCT_2366
Organism: Oscillochloris trichoides DG-6

1uniprot[Pubmed] 21037015
Draft genome sequence of the anoxygenic filamentous phototrophic bacterium Oscillochloris trichoides subsp. DG-6.(J. Bacteriol.) [2011]