| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
Q7WZ80_9ACTO (Q7WZ80) |
|
|
0.0 |
823 |
100% |
|
- Product
- Putative oxygenase OxyC
- Gene
- dbv11
- Organism
- Nonomuraea sp. ATCC 39727
|
1uniprot[Pubmed] 12837387 [Medline] 22721464 The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003] |
|
2
|
E9L1L7_9ZZZZ (E9L1L7) |
|
|
0.0 |
700 |
83% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA878-18
- Organism
- uncultured organism CA878
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
3
|
B7T1E0_9BACT (B7T1E0) |
|
|
0.0 |
678 |
80% |
|
- Product
- Teg15
- Gene
- teg15
- Organism
- uncultured soil bacterium
|
1uniprot[Pubmed] 18987322 Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008] |
|
4
|
Q6ZZI4_ACTTI (Q6ZZI4) |
|
|
0.0 |
665 |
78% |
|
- Product
- P450 monooxygenase
- Gene
-
- Organism
- Actinoplanes teichomyceticus
|
1uniprot[Pubmed] 15113000 Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase.(Chem. Biol.) [2004] |
|
5
|
E9L1I1_9ZZZZ (E9L1I1) |
|
|
0.0 |
662 |
79% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA37-37
- Organism
- uncultured organism CA37
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
6
|
E9L1S6_9ZZZZ (E9L1S6) |
|
|
0.0 |
647 |
76% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA915-34
- Organism
- uncultured organism CA915
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
7
|
Q70AY6_ACTTI (Q70AY6) |
|
|
0.0 |
639 |
79% |
|
- Product
- OxyC protein
- Gene
- tcp22
- Organism
- Actinoplanes teichomyceticus
|
1uniprot[Pubmed] 14702401 Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.(Microbiology) [2004] |
|
8
|
Q8KLM1_STRTO (Q8KLM1) |
|
|
1e-173 |
614 |
76% |
|
- Product
- StaJ
- Gene
-
- Organism
- Streptomyces toyocaensis
|
1uniprot[Pubmed] 9177243 [Medline] 97322398 D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB.(Proc. Natl. Acad. Sci. U.S.A.) [1997] | 2uniprot[Pubmed] 12060705 [Medline] 22080153 Assembling the glycopeptide antibiotic scaffold: the biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009.(Proc. Natl. Acad. Sci. U.S.A.) [2002] | [pubmed all]
|
9
|
B7T1C5_9BACT (B7T1C5) |
|
|
1e-173 |
612 |
73% |
|
- Product
- Veg12
- Gene
- veg12
- Organism
- uncultured soil bacterium
|
1uniprot[Pubmed] 18987322 Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008] |
|
10
|
C5C4_AMYOR (Q8RN03) |
|
|
1e-172 |
608 |
72% |
|
- Product
- Cytochrome P450 165C4
Vancomycin biosynthesis protein OxyC
- Gene
- CYP165C4
oxyC
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 12207020 [Medline] 22344604 Crystal structure of OxyB, a cytochrome P450 implicated in an oxidative phenol coupling reaction during vancomycin biosynthesis.(J. Biol. Chem.) [2002] | 2uniprot[Pubmed] 12888556 Crystal structure of OxyC, a cytochrome P450 implicated in an oxidative C-C coupling reaction during vancomycin biosynthesis.(J. Biol. Chem.) [2003] | [pubmed all]
|
11
|
O87675_9PSEU (O87675) |
|
|
1e-172 |
608 |
73% |
|
- Product
- P450 monooxygenase
- Gene
- oxyC
- Organism
- Amycolatopsis balhimycina
|
1uniprot[Pubmed] 10390204 [Medline] 99318579 Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908.(Antimicrob. Agents Chemother.) [1999] | 2uniprot[Pubmed] 11932455 [Medline] 21930292 Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules.(Microbiology) [2002] | 3uniprot[Pubmed] 11495926 [Medline] 21486455 A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.(J. Biol. Chem.) [2001] | 4uniprot[Pubmed] 12404385 The biosynthesis of vancomycin-type glycopeptide antibiotics - the order of cyclization steps.(Angew. Chem. Int. Ed. Engl.) [2001] | 5uniprot[Pubmed] 11880037 [Medline] 21869276 Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.(Chem. Biol.) [2002] | 6uniprot Precursor-directed biosynthesis for the generation of novel glycopetides.(Ernst Schering Res. Found. Workshop) [2005] | [pubmed all]
|
13
|
O52816_AMYOR (O52816) |
|
|
1e-150 |
534 |
76% |
|
- Product
- PCZA361.27
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 9545426 [Medline] 98212597 Sequencing and analysis of genes involved in the biosynthesis of a vancomycin group antibiotic.(Chem. Biol.) [1998] |
|
15
|
Q93N81_STRLA (Q93N81) |
|
|
1e-111 |
407 |
53% |
|
- Product
- P450-related oxidase
- Gene
-
- Organism
- Streptomyces lavendulae
|
1uniprot[Pubmed] 11447274 [Medline] 21353013 Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
16
|
Q70AY8_ACTTI (Q70AY8) |
|
|
1e-99 |
368 |
51% |
|
- Product
- OxyB protein
- Gene
- tcp20
- Organism
- Actinoplanes teichomyceticus
|
1uniprot[Pubmed] 14702401 Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.(Microbiology) [2004] |
|
17
|
Q7WZ79_9ACTO (Q7WZ79) |
|
|
3e-98 |
363 |
51% |
|
- Product
- Putative OxyB monooxigenase
- Gene
- dbv12
- Organism
- Nonomuraea sp. ATCC 39727
|
1uniprot[Pubmed] 12837387 [Medline] 22721464 The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003] |
|
18
|
O87674_9PSEU (O87674) |
|
|
1e-96 |
358 |
49% |
|
- Product
- P450 monooxygenase
- Gene
- oxyB
- Organism
- Amycolatopsis balhimycina
|
1uniprot[Pubmed] 10390204 [Medline] 99318579 Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908.(Antimicrob. Agents Chemother.) [1999] | 2uniprot[Pubmed] 11932455 [Medline] 21930292 Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules.(Microbiology) [2002] | 3uniprot[Pubmed] 11495926 [Medline] 21486455 A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.(J. Biol. Chem.) [2001] | 4uniprot[Pubmed] 12404385 The biosynthesis of vancomycin-type glycopeptide antibiotics - the order of cyclization steps.(Angew. Chem. Int. Ed. Engl.) [2001] | 5uniprot[Pubmed] 11880037 [Medline] 21869276 Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.(Chem. Biol.) [2002] | 6uniprot Precursor-directed biosynthesis for the generation of novel glycopetides.(Ernst Schering Res. Found. Workshop) [2005] | [pubmed all]
|
19
|
B7T1D6_9BACT (B7T1D6) |
|
|
6e-96 |
355 |
50% |
|
- Product
- Teg11
- Gene
- teg11
- Organism
- uncultured soil bacterium
|
1uniprot[Pubmed] 18987322 Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008] |
|
20
|
Q6ZZI6_ACTTI (Q6ZZI6) |
|
|
3e-95 |
353 |
53% |
|
- Product
- P450 monooxygenase
- Gene
-
- Organism
- Actinoplanes teichomyceticus
|
1uniprot[Pubmed] 15113000 Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase.(Chem. Biol.) [2004] |
|
21
|
Q8KLL9_STRTO (Q8KLL9) |
|
|
9e-95 |
352 |
48% |
|
- Product
- StaH
- Gene
-
- Organism
- Streptomyces toyocaensis
|
1uniprot[Pubmed] 9177243 [Medline] 97322398 D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB.(Proc. Natl. Acad. Sci. U.S.A.) [1997] | 2uniprot[Pubmed] 12060705 [Medline] 22080153 Assembling the glycopeptide antibiotic scaffold: the biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009.(Proc. Natl. Acad. Sci. U.S.A.) [2002] | [pubmed all]
|
22
|
O52823_AMYOR (O52823) |
|
|
2e-94 |
350 |
47% |
|
- Product
- PCZA363.7
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 9545426 [Medline] 98212597 Sequencing and analysis of genes involved in the biosynthesis of a vancomycin group antibiotic.(Chem. Biol.) [1998] |
|
24
|
C5B3_AMYOR (Q8RN04) |
|
|
3e-92 |
343 |
47% |
|
- Product
- Cytochrome P450 165B3
Vancomycin biosynthesis protein OxyB
- Gene
- CYP165B3
oxyB
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 12207020 [Medline] 22344604 Crystal structure of OxyB, a cytochrome P450 implicated in an oxidative phenol coupling reaction during vancomycin biosynthesis.(J. Biol. Chem.) [2002] |
|
25
|
E9L1I0_9ZZZZ (E9L1I0) |
|
|
9e-91 |
338 |
48% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA37-36
- Organism
- uncultured organism CA37
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
26
|
E9L1L5_9ZZZZ (E9L1L5) |
|
|
6e-90 |
336 |
52% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA878-16
- Organism
- uncultured organism CA878
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
27
|
B7T1C4_9BACT (B7T1C4) |
|
|
1e-88 |
332 |
50% |
|
- Product
- Veg11
- Gene
- veg11
- Organism
- uncultured soil bacterium
|
1uniprot[Pubmed] 18987322 Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008] |
|
28
|
E9L1S5_9ZZZZ (E9L1S5) |
|
|
5e-82 |
309 |
45% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA915-33
- Organism
- uncultured organism CA915
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
29
|
Q93N82_STRLA (Q93N82) |
|
|
5e-78 |
296 |
43% |
|
- Product
- P450-related oxidase
- Gene
-
- Organism
- Streptomyces lavendulae
|
1uniprot[Pubmed] 11447274 [Medline] 21353013 Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
30
|
Q0RLG3_FRAAA (Q0RLG3) |
|
|
7e-78 |
295 |
47% |
|
- Product
- Cytochrome P450 FAS1
- Gene
- FRAAL2997
- Organism
- Frankia alni (strain ACN14a)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
32
|
B8YGP5_AMYOR (B8YGP5) |
|
|
3e-73 |
280 |
76% |
|
- Product
- Putative P450 monooxygenase
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 19447951 Detection, distribution, and organohalogen compound discovery implications of the reduced flavin adenine dinucleotide-dependent halogenase gene in major filamentous actinomycete taxonomic groups.(Appl. Environ. Microbiol.) [2009] |
|
33
|
Q2JCL7_FRASC (Q2JCL7) |
|
|
7e-73 |
279 |
44% |
|
- Product
- Cytochrome P450
- Gene
- Francci3_1599
- Organism
- Frankia sp. (strain CcI3)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
39
|
B7T1D5_9BACT (B7T1D5) |
|
|
5e-68 |
263 |
40% |
|
- Product
- Teg10
- Gene
- teg10
- Organism
- uncultured soil bacterium
|
1uniprot[Pubmed] 18987322 Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008] |
|
40
|
C6WFH4_ACTMD (C6WFH4) |
|
|
4e-67 |
259 |
40% |
|
- Product
- Cytochrome P450
- Gene
- Amir_1961
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
41
|
E9L1H9_9ZZZZ (E9L1H9) |
|
|
6e-67 |
259 |
39% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA37-35
- Organism
- uncultured organism CA37
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
46
|
E9L1L4_9ZZZZ (E9L1L4) |
|
|
1e-64 |
252 |
40% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA878-15
- Organism
- uncultured organism CA878
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
47
|
Q5IK44_9ACTO (Q5IK44) |
|
|
1e-64 |
251 |
41% |
|
- Product
- Cytochrome P450
- Gene
- fas1
stPAI015
- Organism
- Streptomyces turgidiscabies
|
1uniprot[Pubmed] 15686551 A large, mobile pathogenicity island confers plant pathogenicity on Streptomyces species.(Mol. Microbiol.) [2005] |
|
48
|
Q8KLL8_STRTO (Q8KLL8) |
|
|
4e-64 |
249 |
38% |
|
- Product
- StaG
- Gene
-
- Organism
- Streptomyces toyocaensis
|
1uniprot[Pubmed] 9177243 [Medline] 97322398 D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB.(Proc. Natl. Acad. Sci. U.S.A.) [1997] | 2uniprot[Pubmed] 12060705 [Medline] 22080153 Assembling the glycopeptide antibiotic scaffold: the biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009.(Proc. Natl. Acad. Sci. U.S.A.) [2002] | [pubmed all]
|
49
|
E9L1S4_9ZZZZ (E9L1S4) |
|
|
5e-64 |
249 |
38% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA915-32
- Organism
- uncultured organism CA915
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
50
|
C7MUK5_SACVD (C7MUK5) |
|
|
1e-63 |
248 |
38% |
|
- Product
- Cytochrome P450
- Gene
- Svir_26970
- Organism
- Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
|
1uniprot Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009] |
|
52
|
Q6ZZI7_ACTTI (Q6ZZI7) |
|
|
5e-62 |
243 |
37% |
|
- Product
- Oxy protein
P450 monooxygenase
- Gene
- tcp19
- Organism
- Actinoplanes teichomyceticus
|
1uniprot[Pubmed] 15113000 Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase.(Chem. Biol.) [2004] | 2uniprot[Pubmed] 20974107 Structural characterization of CYP165D3, a cytochrome P450 involved in phenolic coupling in teicoplanin biosynthesis.(Arch. Biochem. Biophys.) [2011] | 3uniprot[Pubmed] 14702401 Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.(Microbiology) [2004] | [pubmed all]
|
53
|
FAS1_RHOFA (P46373) |
|
|
1e-61 |
242 |
37% |
|
- Product
- Cytochrome P450 FAS1
- Gene
- fas1
CYP105E1
- Organism
- Rhodococcus fascians
|
1uniprot[Pubmed] 8169198 [Medline] 94222824 The fas operon of Rhodococcus fascians encodes new genes required for efficient fasciation of host plants.(J. Bacteriol.) [1994] |
|
54
|
D8I721_AMYMU (D8I721) |
|
|
2e-61 |
241 |
37% |
|
- Product
- Cytochrome P450
- Gene
- AMED_3426
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
57
|
D3Q8N1_STANL (D3Q8N1) |
|
|
9e-60 |
235 |
39% |
|
- Product
- Cytochrome P450
- Gene
- Snas_4832
- Organism
- Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
|
1uniprot Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009] |
|
58
|
Q7WZ78_9ACTO (Q7WZ78) |
|
|
1e-59 |
235 |
38% |
|
- Product
- Putative monooxygenase
- Gene
- dbv13
- Organism
- Nonomuraea sp. ATCC 39727
|
1uniprot[Pubmed] 12837387 [Medline] 22721464 The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003] |
|
60
|
O52822_AMYOR (O52822) |
|
|
3e-59 |
233 |
37% |
|
- Product
- PCZA363.6
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 9545426 [Medline] 98212597 Sequencing and analysis of genes involved in the biosynthesis of a vancomycin group antibiotic.(Chem. Biol.) [1998] |
|
62
|
D3PZ02_STANL (D3PZ02) |
|
|
9e-59 |
232 |
38% |
|
- Product
- Cytochrome P450
- Gene
- Snas_5801
- Organism
- Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
|
1uniprot Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009] |
|
64
|
D3Q1N8_STANL (D3Q1N8) |
|
|
1e-58 |
231 |
38% |
|
- Product
- Cytochrome P450
- Gene
- Snas_0166
- Organism
- Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
|
1uniprot Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009] |
|
65
|
A4FHI7_SACEN (A4FHI7) |
|
|
2e-58 |
231 |
38% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- pteC
SACE_4243
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
66
|
B7T1C3_9BACT (B7T1C3) |
|
|
2e-58 |
231 |
36% |
|
- Product
- Veg10
- Gene
- veg10
- Organism
- uncultured soil bacterium
|
1uniprot[Pubmed] 18987322 Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008] |
|
67
|
D2AYJ7_STRRD (D2AYJ7) |
|
|
5e-58 |
229 |
39% |
|
- Product
- Putative cytochrome P450
- Gene
- Sros_6255
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
68
|
D7B817_NOCDD (D7B817) |
|
|
5e-58 |
229 |
38% |
|
- Product
- Cytochrome P450
- Gene
- Ndas_4942
- Organism
- Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
|
1uniprot Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010] |
|
69
|
Q6ZZI8_ACTTI (Q6ZZI8) |
|
|
9e-58 |
229 |
36% |
|
- Product
- OxyA protein
P450 monooxygenase
- Gene
- tcp18
- Organism
- Actinoplanes teichomyceticus
|
1uniprot[Pubmed] 15113000 Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase.(Chem. Biol.) [2004] | 2uniprot[Pubmed] 14702401 Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.(Microbiology) [2004] | [pubmed all]
|
70
|
D2B7H3_STRRD (D2B7H3) |
|
|
9e-58 |
229 |
37% |
|
- Product
- Putative uncharacterized protein
- Gene
- Sros_8861
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
72
|
C6WLB9_ACTMD (C6WLB9) |
|
|
3e-57 |
227 |
39% |
|
- Product
- Cytochrome P450
- Gene
- Amir_2535
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
74
|
B7T1D4_9BACT (B7T1D4) |
|
|
8e-57 |
226 |
36% |
|
- Product
- Teg9
- Gene
- teg9
- Organism
- uncultured soil bacterium
|
1uniprot[Pubmed] 18987322 Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008] |
|
76
|
E9L1L3_9ZZZZ (E9L1L3) |
|
|
9e-57 |
225 |
37% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA878-14
- Organism
- uncultured organism CA878
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
79
|
F3NRX8_9ACTO (F3NRX8) |
|
|
2e-56 |
224 |
37% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- SGM_5892
- Organism
- Streptomyces griseoaurantiacus M045
|
1uniprot[Pubmed] 21551298 Draft Genome Sequence of the Marine Bacterium Streptomyces griseoaurantiacus M045, Which Produces Novel Manumycin-Type Antibiotics with a pABA Core Component.(J. Bacteriol.) [2011] |
|
81
|
Q595R1_9ACTO (Q595R1) |
|
|
2e-56 |
224 |
37% |
|
- Product
- Cytochrome P450 monooxygenase CYP105S1
- Gene
- cyp230
- Organism
- Streptomyces tubercidicus
|
1uniprot[Pubmed] 16269732 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005] | 2uniprot[Pubmed] 16269733 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005] | [pubmed all]
|
83
|
F2RDD2_STRVP (F2RDD2) |
|
|
3e-56 |
224 |
37% |
|
- Product
- Putative cytochrome P450 hydroxylase
- Gene
- SVEN_6138
- Organism
- Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
|
1uniprot[Pubmed] 21463507 Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011] |
|
84
|
D3Q5W0_STANL (D3Q5W0) |
|
|
3e-56 |
224 |
37% |
|
- Product
- Cytochrome P450
- Gene
- Snas_0545
- Organism
- Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
|
1uniprot Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009] |
|
85
|
Q595S0_9ACTO (Q595S0) |
|
|
4e-56 |
223 |
38% |
|
- Product
- Cytochrome P450 monooxygenase CYP105S2
- Gene
- cyp234
- Organism
- Streptomyces tubercidicus
|
1uniprot[Pubmed] 16269732 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005] | 2uniprot[Pubmed] 16269733 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005] | [pubmed all]
|
86
|
A6YRR3_STRVG (A6YRR3) |
|
|
5e-56 |
223 |
37% |
|
- Product
- Cytochrome P450 monooxygenase 105
- Gene
-
- Organism
- Streptomyces virginiae
|
1uniprot[Pubmed] 19376895 Characterization of P450 FcpC, the Enzyme Responsible for Bioconversion of Diosgenone to Isonuatigenone in Streptomyces virginiae IBL-14.(Appl. Environ. Microbiol.) [2009] |
|
87
|
C5A3_AMYOR (Q8RN05) |
|
|
7e-56 |
223 |
36% |
|
- Product
- Cytochrome P450 165A3
Vancomycin biosynthesis protein OxyA
- Gene
- CYP165A3
oxyA
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 12207020 [Medline] 22344604 Crystal structure of OxyB, a cytochrome P450 implicated in an oxidative phenol coupling reaction during vancomycin biosynthesis.(J. Biol. Chem.) [2002] |
|
88
|
E4NIK7_KITSK (E4NIK7) |
|
|
8e-56 |
222 |
38% |
|
- Product
- Putative cytochrome P450
- Gene
- KSE_70470
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
90
|
F2R215_STRVP (F2R215) |
|
|
2e-55 |
221 |
37% |
|
- Product
- Putative cytochrome P450 hydroxylase
- Gene
- SVEN_7396
- Organism
- Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
|
1uniprot[Pubmed] 21463507 Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011] |
|
91
|
D2BBN4_STRRD (D2BBN4) |
|
|
2e-55 |
221 |
37% |
|
- Product
- Putative cytochrome P450
- Gene
- Sros_3157
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
93
|
E9L1H8_9ZZZZ (E9L1H8) |
|
|
4e-55 |
220 |
36% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA37-34
- Organism
- uncultured organism CA37
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
94
|
O87673_9PSEU (O87673) |
|
|
4e-55 |
220 |
39% |
|
- Product
- P450 monooxygenase
- Gene
- oxyA
- Organism
- Amycolatopsis balhimycina
|
1uniprot[Pubmed] 10390204 [Medline] 99318579 Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908.(Antimicrob. Agents Chemother.) [1999] | 2uniprot[Pubmed] 11932455 [Medline] 21930292 Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules.(Microbiology) [2002] | 3uniprot[Pubmed] 11495926 [Medline] 21486455 A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.(J. Biol. Chem.) [2001] | 4uniprot[Pubmed] 12404385 The biosynthesis of vancomycin-type glycopeptide antibiotics - the order of cyclization steps.(Angew. Chem. Int. Ed. Engl.) [2001] | 5uniprot[Pubmed] 11880037 [Medline] 21869276 Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.(Chem. Biol.) [2002] | 6uniprot Precursor-directed biosynthesis for the generation of novel glycopetides.(Ernst Schering Res. Found. Workshop) [2005] | [pubmed all]
|
95
|
Q7WZ77_9ACTO (Q7WZ77) |
|
|
9e-55 |
219 |
35% |
|
- Product
- Putative OxyA monooxygenase
- Gene
- dbv14
- Organism
- Nonomuraea sp. ATCC 39727
|
1uniprot[Pubmed] 12837387 [Medline] 22721464 The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003] |
|
96
|
D8HSX6_AMYMU (D8HSX6) |
|
|
9e-55 |
219 |
39% |
|
- Product
- Cytochrome P450
- Gene
- AMED_0028
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
97
|
D2B3A2_STRRD (D2B3A2) |
|
|
2e-54 |
218 |
41% |
|
- Product
- Putative cytochrome P450
- Gene
- Sros_4555
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
99
|
D8HZ81_AMYMU (D8HZ81) |
|
|
2e-54 |
218 |
39% |
|
- Product
- Cytochrome P450
- Gene
- AMED_0616
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
100
|
O52544_AMYMD (O52544) |
|
|
2e-54 |
218 |
39% |
|
- Product
- Putative cytochrome P450-like protein
- Gene
-
- Organism
- Amycolatopsis mediterranei
Nocardia mediterranei
|
1uniprot[Pubmed] 9512878 [Medline] 98174059 Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998] | 2uniprot[Pubmed] 9497318 [Medline] 98165773 3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998] | 3uniprot[Pubmed] 11278540 [Medline] 21201076 Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001] | [pubmed all]
|