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微生物 : Streptomyces clavuligerus

微生物株情報

NBRC番号 13307
学名 Streptomyces clavuligerus
別名（シノニム） 該当データなし
由来 IFO 13307 <- Eli Lilly & Co.
他保存機関番号 AS 4.1611=ATCC 27064=BCRC 11518=CBS 226.75=CECT 3125=DSM 40751=DSM 738=JCM 4710=KCTC 9095=NCIMB 12785=NRRL 3585=VKM Ac-602
他株番号 IMET 43657
参考文献
20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways. (Genome Biol Evol. 2010)
20889745
Draft genome sequence of Streptomyces clavuligerus NRRL 3585, a producer of diverse secondary metabolites. (J Bacteriol. 2010)
21041678
Identification of the gene cluster for the dithiolopyrrolone antibiotic holomycin in Streptomyces clavuligerus. (Proc Natl Acad Sci U S A. 2010)

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タイプパターン 構成遺伝子 該当CDS
Alanine racemization(NFUNC_0063)
必須A
ALR
(NRULE_0228)
Alanine racemaseSCLAV_3445 SCLAV_3678
Aminoglycoside resistance (by aminoglycoside N-acetyltransferase)(NFUNC_0041)
必須A
AAC3
(NRULE_0149)
Aminoglycoside N(3')-acetyltransferaseSCLAV_0950
Aminoglycoside resistance (by aminoglycoside O-phosphotransferase)(NFUNC_0043)
必須A
APH6
(NRULE_0155)
Streptomycin 6-kinaseSCLAV_3237 SCLAV_p0838 SCLAV_p0259 SCLAV_4596
Ampicillin resistance(NFUNC_0046)
必須A
BLAA
(NRULE_0122)
Beta-lactamase class ASCLAV_3128
Anthranilate biosynthesis(NFUNC_0038)
必須A
GLAT
(NRULE_0142)
Glutamine amidotransferaseSCLAV_2943
TRPE
(NRULE_0143)
Anthranilate synthase component ISCLAV_1250
Bacitracin resistance(NFUNC_0022)
必須A
UPPP
(NRULE_0097)
Undecaprenyl-diphosphataseSCLAV_0574
Beta-lactam antibiotic resistance(NFUNC_0033)
必須A
BLAA
(NRULE_0122)
Beta-lactamase class ASCLAV_3128
Betaine biosynthesis (from choline)(NFUNC_0049)
必須C
CHOX
(NRULE_0178)
Choline oxidaseSCLAV_5678
Ectoine biosynthesis(NFUNC_0056)
必須A
ECTB
(NRULE_0186)
Diaminobutyrate--2-oxoglutarate transaminaseSCLAV_3449 SCLAV_1076
ECTA
(NRULE_0187)
L-2,4-diaminobutyric acid acetyltransferaseSCLAV_1075 SCLAV_3448
ECTC
(NRULE_0188)
L-ectoine synthaseSCLAV_1077
GABA biosynthesis(NFUNC_0066)
必須A
GAD
(NRULE_0231)
Glutamate decarboxylaseSCLAV_2421
O-Glycan degradation(NFUNC_0084)
必須A
ENGBF
(NRULE_0257)
Endo-alpha-N-acetylgalactosaminidaseSCLAV_1212
Hyaluronan degradation(NFUNC_0069)
必須A
HYSA
(NRULE_0232)
Hyaluronate lyaseSCLAV_4483
Hydroxyectoine biosynthesis(NFUNC_0057)
必須A
ECTD
(NRULE_0189)
Ectoine hydroxylaseSCLAV_1078
任意 
ECTB
(NRULE_0186)
Diaminobutyrate--2-oxoglutarate transaminaseSCLAV_3449 SCLAV_1076
 
ECTA
(NRULE_0187)
L-2,4-diaminobutyric acid acetyltransferaseSCLAV_3448 SCLAV_1075
 
ECTC
(NRULE_0188)
L-ectoine synthaseSCLAV_1077
Macrolide antibiotic resistance(NFUNC_0045)
必須D
ERE
(NRULE_0168)
Erythromycin esteraseSCLAV_p0746
F
MGT
(NRULE_0170)
Macrolide glycosyltransferaseSCLAV_p0637 SCLAV_4887
Metal-binding protein(NFUNC_0105)
必須A
MOP
(NRULE_0322)
Putative molybdenum-binding proteinSCLAV_1650 SCLAV_1652
C
MODA
(NRULE_0324)
Molybdate ABC transporter substrate-binding proteinSCLAV_1651 SCLAV_2084
F
SOXR
(NRULE_0329)
Redox-sensitive transcriptional activator SoxRSCLAV_0925 SCLAV_5436
Molybdate transport (ABC transporter)(NFUNC_0097)
必須A
MODA
(NRULE_0324)
Molybdate ABC transporter substrate-binding proteinSCLAV_2084 SCLAV_1651
任意 
MODB
(NRULE_0325)
Molybdate ABC transporter permease proteinSCLAV_1650
Penicillin resistance(NFUNC_0047)
必須A
BLAA
(NRULE_0122)
Beta-lactamase class ASCLAV_3128
Pyrroloquinoline quinone biosynthesis(NFUNC_0020)
必須A
PQQC
(NRULE_0092)
Pyrroloquinoline-quinone synthaseSCLAV_5105
任意 
PQQB
(NRULE_0091)
Coenzyme PQQ synthesis protein BSCLAV_5104
 
PQQE
(NRULE_0094)
Coenzyme PQQ synthesis protein ESCLAV_5107
Riboflavin biosynthesis(NFUNC_0058)
必須A
RIBB
(NRULE_0200)
3,4-dihydroxy-2-butanone 4-phosphate synthaseSCLAV_0678
RIBA
(NRULE_0201)
GTP cyclohydrolase-2SCLAV_0678
RIBD
(NRULE_0202)
Riboflavin biosynthesis protein RibDSCLAV_0681
RIBH
(NRULE_0203)
6,7-dimethyl-8-ribityllumazine synthaseSCLAV_0677
RIBE
(NRULE_0204)
Riboflavin synthaseSCLAV_0680
任意 
RIBF
(NRULE_0205)
Riboflavin biosynthesis protein RibFSCLAV_4606
Streptomycin resistance(NFUNC_0054)
必須C
APH6
(NRULE_0155)
Streptomycin 6-kinaseSCLAV_4596 SCLAV_p0259 SCLAV_p0838 SCLAV_3237
Trehalose biosynthesis (from maltooligosaccharide)(NFUNC_0037)
必須A
TREY
(NRULE_0140)
Maltooligosyl trehalose synthaseSCLAV_4879
TREZ
(NRULE_0141)
Malto-oligosyltrehalose trehalohydrolaseSCLAV_4873
任意 
GLGX
(NRULE_0139)
Glycogen debranching enzymeSCLAV_4880
Trehalose biosynthesis (from maltose)(NFUNC_0034)
必須B
TRES
(NRULE_0128)
Trehalose synthaseSCLAV_4349
Uptake of osmoprotectant(NFUNC_0061)
必須B
EHUB
(NRULE_0216)
Ectoine ABC transporter substrate-binding proteinSCLAV_1978
EHUC
(NRULE_0217)
Ectoine ABC transporter permease proteinSCLAV_1979
EHUD
(NRULE_0218)
Ectoine ABC transporter permease proteinSCLAV_1980
EHUA
(NRULE_0219)
Ectoine ABC transporter ATP-binding proteinSCLAV_1981
C
BCCT
(NRULE_0220)
BCCT family transporterSCLAV_5215
Vitamin B6 biosynthesis (PdxS/PdxT pathway)(NFUNC_0059)
必須A
PDXS
(NRULE_0206)
Pyridoxal biosynthesis lyase PdxSSCLAV_0754
PDXT
(NRULE_0207)
Glutamine amidotransferase subunit PdxTSCLAV_0753

ゲノム配列情報

BioProject IDPRJNA42475
ローカスタグSCLAV
INSDC entriesADGD01000000
ステータスWGS
解析状況
コンティグ数279
サイズ(bp) 8,528,397
遺伝子数 7,291
フィニッシングゴール
アセンブル方法Celera Assembler v. 3.10
冗長度11.8x
シーケンス方法
  • ABI
参考文献
  • The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways. (Genome Biol Evol. 2010) PMID: 20624727

データダウンロード

ゲノム塩基配列 CDS塩基配列 CDSアミノ酸変換配列 遺伝子/ORF リスト
FASTA
gz		 FASTA
gz		 FASTA
gz		 TSV
uncompressed
2.4 MB 2.2 MB 1.5 MB 546.9 KB