Microbe : Bacillus atrophaeus

Microbe Description

NBRC No.	13721
Scientific name	Bacillus atrophaeus
Synonymous name	Not assigned
History	IFO 13721 <- IFO (K. Imai, 9372-2, single colony isolate) <- ATCC 9372 <- N.R. Smith, 1221A <- Bacom Labs. <- C.R. Phillips <- E. McCoy
Other culture collection No.	ATCC 9372=CIP 77.18=DSM 675=NBRC 16183=NCIB 8058=NCIMB 13498
Other No.	1221A=9372-2
Reference	9651440 A simple phenylalanine method for detecting phenylketonuria in large populations of newborn infants, by Robert Guthrie and Ada Susi, Pediatrics, 1963;32:318-343. (Pediatrics. 1998) 10425781 Relationship of Bacillus subtilis clades associated with strains 168 and W23: a proposal for Bacillus subtilis subsp. subtilis subsp. nov. and Bacillus subtilis subsp. spizizenii subsp. nov. (Int J Syst Bacteriol. 1999) 11211269 Reclassification of bioindicator strains Bacillus subtilis DSM 675 and Bacillus subtilis DSM 2277 as Bacillus atrophaeus. (Int J Syst Evol Microbiol. 2001)

Functional Potential >>Details


Type	Pattern	Component Gene		CDS
Alanine racemization(NFUNC_0063)
Require	A	ALR (NRULE_0228)	Alanine racemase	BATRMS_17_01070 BATRMS_06_00270
Aminoglycoside resistance (by aminoglycoside O-nucleotidyltransferase)(NFUNC_0042)
Require	A	ANT6 (NRULE_0151)	Aminoglycoside 6-adenylyltransferase	BATRMS_13_00670
Aminoglycoside resistance (by aminoglycoside O-phosphotransferase)(NFUNC_0043)
Require	A	APH6 (NRULE_0155)	Streptomycin 6-kinase	BATRMS_10_04180
Ampicillin resistance(NFUNC_0046)
Require	A	BLAA (NRULE_0122)	Beta-lactamase class A	BATRMS_13_00950
Participant		BLAD (NRULE_0125)	Beta-lactamase class D	BATRMS_21_00040 BATRMS_04_00070
Anthranilate biosynthesis(NFUNC_0038)
Require	A	GLAT (NRULE_0142)	Glutamine amidotransferase	BATRMS_24_00520
Require	A	TRPE (NRULE_0143)	Anthranilate synthase component I	BATRMS_17_02170
Arginine degradation(NFUNC_0074)
Require	A	ARGI (NRULE_0239)	Arginase	BATRMS_01_01700
Aromatic azo compounds degradation(NFUNC_0073)
Require	A	AZOR (NRULE_0236)	FMN-dependent NADH-azoreductase	BATRMS_17_00430 BATRMS_15_00210
Require	B	AZR (NRULE_0237)	NADPH azoreductase	BATRMS_10_08510
Arsenical resistance(NFUNC_0004)
Require	B	ARSB1 (NRULE_0015)	Arsenical pump membrane protein	BATRMS_04_00270
Require	B	ARSC2 (NRULE_0018)	Arsenate reductase	BATRMS_04_00260
Bacitracin resistance(NFUNC_0022)
Require	A	UPPP (NRULE_0097)	Undecaprenyl-diphosphatase	BATRMS_20_00180
Beta-lactam antibiotic resistance(NFUNC_0033)
Require	A	BLAA (NRULE_0122)	Beta-lactamase class A	BATRMS_13_00950
Require	D	BLAD (NRULE_0125)	Beta-lactamase class D	BATRMS_04_00070 BATRMS_21_00040
Betaine biosynthesis (from choline)(NFUNC_0049)
Require	B	GBSB (NRULE_0176)	Alcohol dehydrogenase	BATRMS_20_00080
Require	B	BETB (NRULE_0177)	Betaine aldehyde dehydrogenase	BATRMS_20_00090
Biotin biosynthesis(NFUNC_0051)
Require	A	BIOF (NRULE_0182)	8-amino-7-oxononanoate synthase	BATRMS_10_00630 BATRMS_05_00780
		BIOA (NRULE_0183)	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	BATRMS_05_00770
		BIOD (NRULE_0184)	ATP-dependent dethiobiotin synthetase BioD	BATRMS_05_00790
		BIOB (NRULE_0185)	Biotin synthase	BATRMS_05_00800
Chloramphenicol resistance(NFUNC_0025)
Require	A	CAT1 (NRULE_0107)	Chloramphenicol acetyltransferase	BATRMS_10_00620
Fosfomycin resistance(NFUNC_0023)
Require	B	FOSB (NRULE_0099)	Metallothiol transferase FosB	BATRMS_01_00220
Macrolide antibiotic resistance(NFUNC_0045)
Require	D	ERE (NRULE_0168)	Erythromycin esterase	BATRMS_16_00270
Require	E	MPH (NRULE_0169)	Macrolide 2'-phosphotransferase	BATRMS_16_00480
Metal-binding protein(NFUNC_0105)
Require	A	MOP (NRULE_0322)	Putative molybdenum-binding protein	BATRMS_01_00080 BATRMS_11_00990
	C	MODA (NRULE_0324)	Molybdate ABC transporter substrate-binding protein	BATRMS_11_01840 BATRMS_17_05340
	D	MNTR (NRULE_0327)	DtxR family transcriptional regulator MntR	BATRMS_17_04870
Milk clotting(NFUNC_0072)
Require	A	MCP (NRULE_0235)	Milk-clotting protease	BATRMS_10_02980
Molybdate transport (ABC transporter)(NFUNC_0097)
Require	A	MODA (NRULE_0324)	Molybdate ABC transporter substrate-binding protein	BATRMS_17_05340 BATRMS_11_01840
Participant		MODB (NRULE_0325)	Molybdate ABC transporter permease protein	BATRMS_11_01850
(R)-pantothenate biosynthesis(NFUNC_0030)
Require	A	PAND (NRULE_0115)	Aspartate 1-decarboxylase	BATRMS_17_01890
		PANB (NRULE_0116)	3-methyl-2-oxobutanoate hydroxymethyltransferase	BATRMS_17_01910
		PANE (NRULE_0117)	2-dehydropantoate 2-reductase	BATRMS_10_02530 BATRMS_17_06220 BATRMS_10_03260
		PANC (NRULE_0118)	Pantothenate synthetase	BATRMS_17_01900
Penicillin resistance(NFUNC_0047)
Require	A	BLAA (NRULE_0122)	Beta-lactamase class A	BATRMS_13_00950
Require	B	BLAD (NRULE_0125)	Beta-lactamase class D	BATRMS_04_00070 BATRMS_21_00040
Phytic acid hydrolysis(NFUNC_0085)
Require	A	PHYT (NRULE_0258)	3-phytase	BATRMS_17_01050
Riboflavin biosynthesis(NFUNC_0058)
Require	A	RIBB (NRULE_0200)	3,4-dihydroxy-2-butanone 4-phosphate synthase	BATRMS_17_02760
		RIBA (NRULE_0201)	GTP cyclohydrolase-2	BATRMS_17_02760
		RIBD (NRULE_0202)	Riboflavin biosynthesis protein RibD	BATRMS_17_02780
		RIBH (NRULE_0203)	6,7-dimethyl-8-ribityllumazine synthase	BATRMS_17_02750
		RIBE (NRULE_0204)	Riboflavin synthase	BATRMS_17_02770
Participant		RIBF (NRULE_0205)	Riboflavin biosynthesis protein RibF	BATRMS_10_00950
Streptomycin resistance(NFUNC_0054)
Require	A	ANT6 (NRULE_0151)	Aminoglycoside 6-adenylyltransferase	BATRMS_13_00670
Require	C	APH6 (NRULE_0155)	Streptomycin 6-kinase	BATRMS_10_04180
Uptake of osmoprotectant(NFUNC_0061)
Require	A	OPUAC (NRULE_0213)	Osmoprotectant ABC transporter substrate-binding protein	BATRMS_14_00020 BATRMS_16_00940 BATRMS_15_00040
		OPUAB (NRULE_0214)	Osmoprotectant ABC transporter permease protein	BATRMS_15_00030 BATRMS_14_00010 BATRMS_14_00030 BATRMS_15_00050 BATRMS_16_00930
		OPUAA (NRULE_0215)	Osmoprotectant ABC transporter ATP-binding protein	BATRMS_27_00130 BATRMS_15_00020 BATRMS_14_00040 BATRMS_16_00920
	C	BCCT (NRULE_0220)	BCCT family transporter	BATRMS_05_00930
	E	OPUE (NRULE_0222)	Sodium/proline symporter	BATRMS_18_00810 BATRMS_16_01140
Vitamin B6 biosynthesis (PdxS/PdxT pathway)(NFUNC_0059)
Require	A	PDXS (NRULE_0206)	Pyridoxal biosynthesis lyase PdxS	BATRMS_03_00130
Require	A	PDXT (NRULE_0207)	Glutamine amidotransferase subunit PdxT	BATRMS_03_00120

Genomic Overview

BioProject ID	PRJNA37683
Locus_tag	BATRMS
INSDC entries	AEFM01000000
Sequence status	WGS
Current status
Contig number	28
Size(bp)	4,106,324
Gene	0
Finishing goal
Assembly method	Newbler v. 2.0.01.14
Coverage	44x
Technology	454 FLX

Reference

Genomic signatures of strain selection and enhancement in Bacillus atrophaeus var. globigii, a historical biowarfare simulant. (PLoS One. 2011) PMID: 21464989

Data Download

Genomic nucleotide sequence	Nucleotide sequence of the coding regions	Translation of the coding sequneces	List of genes / ORFs
FASTA gz	FASTA gz	FASTA gz	TSV uncompressed

1.2 MB	1.1 MB	770.4 KB	344.4 KB