遺伝子 : 2-dehydropantoate 2-reductase (PANE)

遺伝子情報

ID	NRULE_0117
遺伝子ID	PANE
作成日	2013/01/21
タンパク質名	Protein name Full 2-dehydropantoate 2-reductase EC EC 1.1.1.169 Synonym Full Ketopantoate reductase Short KPA reductase KPR
遺伝子名	panE
遺伝子条件	PFAM; PF02558; hit=1ANDPFAM; PF08546; hit=1
参照	Gene Ontology GO GO:0005737, C:cytoplasm, IEA:UniProtKB-SubCell GO:0008677, F:2-dehydropantoate 2-reductase activity, IDA:EcoCyc GO:0050661, F:NADP binding, IDA:EcoCyc GO:0033317, P:pantothenate biosynthetic process from valine, IMP:EcoCyc Phylogenomic databases eggNOG COG1893, - HOGENOM HOG000050223, - KO K00077, - ProtClustDB PRK06522, - Enzyme and pathway databases BioCyc MetaCyc:2-DEHYDROPANTOATE-REDUCT-MONOMER, - UniPathway UPA00028, UER00004 Family and domain databases InterPro IPR008927, 6-PGluconate_DH_C-like IPR003710, ApbA IPR013752, ApbA_C IPR013332, ApbA_N IPR013328, DH_multihelical IPR016040, NAD(P)-bd_dom Pfam PF02558, ApbA, 1 PF08546, ApbA_C, 1 TIGRFAMs TIGR00745, apbA_panE, 1
配列の特徴	P0A9J4 Escherichia coli (strain K12). NP_BIND 7 - 12 NADP. ACT_SITE 176 Proton donor. BINDING 31 NADP; via amide nitrogen. BINDING 98 NADP; via amide nitrogen. BINDING 98 Substrate. BINDING 122 NADP; via amide nitrogen and carbonyl oxygen. BINDING 180 Substrate. BINDING 184 Substrate. BINDING 194 Substrate. BINDING 241 Substrate. BINDING 244 Substrate. BINDING 256 NADP.
注釈	Function Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid Catalytic activity (R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH Pathway Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 2/2 Subunit structure Monomer Sequence similarities Belongs to the ketopantoate reductase family
参考文献	P0A9J4 Escherichia coli (strain K12). 9278503 The complete genome sequence of Escherichia coli K-12. (Science. 1997) 10736170 Kinetic and mechanistic analysis of the E. coli panE-encoded ketopantoate reductase. (Biochemistry. 2000)

関与する機能

機能名
(R)-pantothenate biosynthesis

該当CDS

学名	NBRC番号	CDS	タンパク質名
Acetobacter pasteurianus	105190	APA32_12730	Ketopantoate reductase ApbA/PanE
		APA32_22010	Ketopantoate reductase ApbA/PanE
Acetobacter pasteurianus	101655	APT_1408	ketopantoate reductase ApbA/PanE
		APT_2197	ketopantoate reductase ApbA/PanE
Acetobacter tropicalis	101654	ATPR_0334	ketopantoate reductase ApbA/PanE
		ATPR_1991	ketopantoate reductase ApbA/PanE
Acidiphilium multivorum	100883	ACMV_02160	putative 2-dehydropantoate 2-reductase
		ACMV_27780	putative 2-dehydropantoate 2-reductase
Actinoalloteichus cyanogriseus	14455	G443_08_00870	2-dehydropantoate 2-reductase
Actinoalloteichus spitiensis	102582	ACTIDRAF_19950	hypothetical protein
Actinoplanes missouriensis	102363	AMIS_63930	putative 2-dehydropantoate 2-reductase
Aeropyrum pernix	100138	APE_0677.1	2-dehydropantoate 2-reductase (ketopantoate reductase) (KPA reductase) (KPR)
Alicyclobacillus acidocaldarius subsp. acidocaldarius	15652	Aaci_2865	2-dehydropantoate 2-reductase
Alteromonas macleodii	102226	MASE_05470	2-dehydropantoate 2-reductase
		MASE_06125	2-dehydropantoate 2-reductase
Amycolatopsis azurea	14573	C791_3906	2-dehydropantoate 2-reductase
Amycolatopsis mediterranei	13415	RAM_23300	2-dehydropantoate 2-reductase
		RAM_37340	2-dehydropantoate 2-reductase
Anaerolinea thermophila	100420	ANT_20830	putative 2-dehydropantoate 2-reductase
Anoxybacillus flavithermus	15317	Aflv_1841	Ketopantoate reductase
Aquifex aeolicus		aq_1727	putative protein
Archaeoglobus profundus	100127	Arcpr_0108	2-dehydropantoate 2-reductase
Ardenticatena maritima		ARMA_1041	2-dehydropantoate 2-reductase
		ARMA_2707	2-dehydropantoate 2-reductase
Austwickia chelonae	105200	AUCHE_16_01130	putative 2-dehydropantoate 2-reductase
Azorhizobium caulinodans	14845	AZC_0464	2-dehydropantoate 2-reductase
Bacillus amyloliquefaciens	15535	BAMF_1518	ketopantoate reductase
		BAMF_1585	2-dehydropantoate 2-reductase
Bacillus atrophaeus	13721	BATRMS_10_02530	2-dehydropantoate 2-reductase
		BATRMS_10_03260	2-dehydropantoate 2-reductase
		BATRMS_17_06220	2-dehydropantoate 2-reductase
Bacillus cereus	15305	BC_1806	2-dehydropantoate 2-reductase
		BC_3920	2-dehydropantoate 2-reductase
Bacillus licheniformis	12200	BL05158	2-dehydropantoate 2-reductase
Bacillus licheniformis	12195	BLi01728	ketopantoate reductase YlbQ
Bacillus mojavensis	15718	GYU_15_00620	2-dehydropantoate 2-reductase
		GYU_15_01330	2-dehydropantoate 2-reductase
Bacillus mycoides	101228	bmyco0001_16580	2-dehydropantoate 2-reductase
		bmyco0001_35440	2-dehydropantoate 2-reductase
Bacillus pseudomycoides	101232	bpmyx0001_16730	2-dehydropantoate 2-reductase
		bpmyx0001_33950	2-dehydropantoate 2-reductase
Bacillus psychrosaccharolyticus	101233	WYK_185_00020	2-dehydropantoate 2-reductase
		WYK_192_00090	2-dehydropantoate 2-reductase
		WYK_252_00090	2-dehydropantoate 2-reductase
Bacillus pumilus	12092	BAT_2638	2-dehydropantoate 2-reductase
Bacillus subtilis	3134	BSU6633_08291	2-dehydropantoate 2-reductase
		BSU6633_10501	2-dehydropantoate 2-reductase
Bacillus subtilis subsp. subtilis	13719	BSU14440	ketopantoate reductase
		BSU15110	2-dehydropantoate 2-reductase
Bacillus thuringiensis	101235	bthur0008_16890	2-dehydropantoate 2-reductase
		bthur0008_36490	2-dehydropantoate 2-reductase
Bacillus vallismortis	101236	BvalD_010100002022	2-dehydropantoate 2-reductase
		BvalD_010100004319	2-dehydropantoate 2-reductase
Bacteroides vulgatus	14291	BVU_1204	putative oxidoreductase
Beutenbergia cavernae	16432	Bcav_4029	2-dehydropantoate 2-reductase
Bradyrhizobium diazoefficiens	14792	bll0134	putative oxidoreductase
		bll3147	putative 2-dehydropantoate 2-reductase (EC 1.1.1.169)
		bll4604	putative oxidoreductase
		bll6396	putative 2-dehydropantoate 2-reductase (EC 1.1.1.169)
		blr0117	putative 2-dehydropantoate 2-reductase (EC 1.1.1.169)
		blr0589	probable 2-dehydropantoate 2-reductase (EC 1.1.1.169)
Brevibacillus brevis	100599	BBR47_38540	2-dehydropantoate 2-reductase
		BBR47_49240	putative 2-dehydropantoate 2-reductase
Brevibacterium linens	12170	BlinB_010200011326	2-dehydropantoate 2-reductase
Brevundimonas subvibrioides	16000	Bresu_2767	2-dehydropantoate 2-reductase
Caldilinea aerophila	104270	CLDAP_08250	putative 2-dehydropantoate 2-reductase
Caldisericum exile	104410	CSE_14470	hypothetical protein
Calditerrivibrio nitroreducens	101217	Calni_0201	2-dehydropantoate 2-reductase
		Calni_0607	2-dehydropantoate 2-reductase
Candidatus Solibacter usitatus		Acid_0666	2-dehydropantoate 2-reductase
Catenulispora acidiphila	102108	Caci_0833	2-dehydropantoate 2-reductase
		Caci_3116	Ketopantoate reductase ApbA/PanE domain protein
		Caci_4552	2-dehydropantoate 2-reductase
Chloracidobacterium thermophilum B		Cabther_A0704	2-dehydropantoate 2-reductase
Chryseobacterium gleum	15054	HMPREF0204_14278	2-dehydropantoate 2-reductase
Chthoniobacter flavus		CfE428DRAFT_3880	2-dehydropantoate 2-reductase
Clostridium acetobutylicum	13948	CA_C1605	Ketopantoate reductase
		CA_C2937	Ketopantoate reductase PanE/ApbA
Clostridium kluyveri	12016	CKR_1942	hypothetical protein
Conexibacter woesei	100937	Cwoe_1046	2-dehydropantoate 2-reductase
Congregibacter litoralis	104960	KT71_10537	ketopantoate reductase
		KT71_14304	ketopantoate reductase
Coprobacillus sp.		HMPREF1021_00331	2-dehydropantoate 2-reductase
Coraliomargarita akajimensis		Caka_2235	2-dehydropantoate 2-reductase
Corynebacterium ammoniagenes	12612	HMPREF0281_01289	2-dehydropantoate 2-reductase
Corynebacterium callunae	15359	H924_05125	2-dehydropantoate 2-reductase
Corynebacterium efficiens	100395	CE1145	conserved hypothetical protein
Corynebacterium glutamicum	12168	Cgl1089	Ketopantoate reductase
Corynebacterium glutamicum	12153	KIQ_09285	2-dehydropantoate 2-reductase
Corynebacterium matruchotii	15360	HMPREF0299_5495	2-dehydropantoate 2-reductase
Corynebacterium striatum	15291	HMPREF0308_2220	2-dehydropantoate 2-reductase
Corynebacterium terpenotabidum	14764	A606_05375	2-dehydropantoate 2-reductase
Cupriavidus metallidurans	102507	Rmet_4356	2-dehydropantoate 2-reductase
		Rmet_5770	2-dehydropantoate 2-reductase (Ketopantoate reductase) (KPA reductase) (KPR)
Cystobacter fuscus	100088	D187_001625	2-dehydropantoate 2-reductase
		D187_007692	2-dehydropantoate 2-reductase
Deferribacter desulfuricans	101012	DEFDS_2126	conserved hypothetical protein
Deinococcus proteolyticus	101906	Deipr_0570	2-dehydropantoate 2-reductase
Edwardsiella tarda	105688	ET1_20_00910	2-dehydropantoate 2-reductase
Enterobacter aerogenes	13534	EAE_12600	2-dehydropantoate 2-reductase
		EAE_16640	2-dehydropantoate 2-reductase
Enterobacter cloacae subsp. cloacae	13535	ECL_01182	2-dehydropantoate 2-reductase
		ECL_03147	2-dehydropantoate 2-reductase
Enterobacter hormaechei	105718	HMPREF9086_1275	ketopantoate reductase family oxidoreductase
		HMPREF9086_1480	2-dehydropantoate 2-reductase
Enterococcus gilvus	100696	I592_00989	2-dehydropantoate 2-reductase
		I592_03139	hypothetical protein
Enterococcus hirae	3181	EHR_06495	2-dehydropantoate 2-reductase
Enterococcus italicus	107825	HMPREF9088_1394	2-dehydropantoate 2-reductase
Enterococcus pallens	100697	I588_03742	hypothetical protein
Enterococcus phoeniculicola	100711	I589_00498	2-dehydropantoate 2-reductase
		I589_02581	2-dehydropantoate 2-reductase
Escherichia coli	3972	EcolC_3208	2-dehydropantoate 2-reductase
Escherichia coli	13500	WFL_02445	2-dehydropantoate 2-reductase
Escherichia coli	12713	Y75_0414	2-dehydropantoate reductase, NADPH-specific
Escherichia fergusonii	102419	EFER_2600	2-dehydropantoate reductase, NADPH-specific
Escherichia hermannii	105704	EH105704_01_09730	2-dehydropantoate 2-reductase
		EH105704_02_04370	putative 2-dehydropantoate 2-reductase
Fibrobacter succinogenes		Fisuc_0919	2-dehydropantoate 2-reductase
Finegoldia magna		FMG_1580	putative 2-dehydropantoate 2-reductase
Flexibacter litoralis	15988	Fleli_2278	2-dehydropantoate 2-reductase
Frateuria aurantia	3245	Fraau_0824	2-dehydropantoate 2-reductase
Fructobacillus fructosus	3516	EWM_18_00560	2-dehydropantoate 2-reductase
Gemmatimonas aurantiaca	100505	GAU_0116	putative 2-dehydropantoate 2-reductase
		GAU_0251	putative 2-dehydropantoate 2-reductase
Geodermatophilus obscurus	13315	Gobs_3881	2-dehydropantoate 2-reductase
Gluconacetobacter hansenii	14816	GXY_07720	2-dehydropantoate 2-reductase
Gordonia aichiensis	108223	GOACH_14_00100	ketopantoate reductase PanE/ApbA family protein
Gordonia otitidis	100426	GOOTI_128_00080	2-dehydropantoate 2-reductase
Gordonia polyisoprenivorans	16320	GOPIP_028_00660	ketopantoate reductase PanE/ApbA family protein
		GOPIP_075_00770	2-dehydropantoate 2-reductase
Gordonia rhizosphera	16068	GORHZ_245_00090	ketopantoate reductase PanE/ApbA family protein
Gordonia sputi	100414	GOSPT_088_00210	putative ketopantoate reductase PanE/ApbA family protein
Haloarcula vallismortis	14741	C437_08581	2-dehydropantoate 2-reductase
		C437_17712	2-dehydropantoate 2-reductase
Halobacillus halophilus	102448	HBHAL_1828	2-dehydropantoate 2-reductase
		HBHAL_2864	2-dehydropantoate 2-reductase
Halobacterium sp.		VNG_0730C	conserved hypothetical protein
Halomonas elongata	15536	HELO_2300	2-dehydropantoate 2-reductase
Holophaga foetida		HOLFODRAFT_RS0202900	2-dehydropantoate 2-reductase
Hylemonella gracilis	14920	HGR_05876	ketopantoate reductase ApbA/PanE
		HGR_10782	2-dehydropantoate 2-reductase
		HGR_13684	2-dehydropantoate 2-reductase
Intrasporangium calvum	12989	Intca_0399	Ketopantoate reductase ApbA/PanE domain protein
Kineococcus radiotolerans	101839	Krad_4304	2-dehydropantoate 2-reductase
Kineosphaera limosa	100340	KILIM_051_00440	putative 2-dehydropantoate 2-reductase
Kitasatospora setae	14216	KSE_02720	putative ketopantoate reductase
		KSE_15110	putative ketopantoate reductase PanE/ApbA family protein
Klebsiella pneumoniae	14438	KPR_4343
Klebsiella pneumoniae subsp. rhinoscleromatis	105682	HMPREF0484_2627	2-dehydropantoate 2-reductase
Kribbella flavida	14399	Kfla_1888	2-dehydropantoate 2-reductase
		Kfla_2127	2-dehydropantoate 2-reductase
Kyrpidia tusciae	15312	Btus_3025	2-dehydropantoate 2-reductase
Labrenzia aggregata	16684	SIAM614_26396	2-dehydropantoate 2-reductase
Lactobacillus acidipiscis	102164	LaciK1_010100004787	2-dehydropantoate 2-reductase
		LaciK1_010100008639	2-dehydropantoate 2-reductase
Lactobacillus casei	15883	LCABL_16650	2-dehydropantoate 2-reductase
Lactobacillus farciminis	107150	LfarK3_010100001152	2-dehydropantoate 2-reductase
Lactobacillus fermentum	15885	HMPREF0511_0504	2-dehydropantoate 2-reductase
Lactobacillus fermentum	3956	LAF_0343	2-dehydropantoate 2-reductase
		LAF_0742	2-dehydropantoate 2-reductase
Lactobacillus fructivorans	13954	LACFR_08_02830	2-dehydropantoate 2-reductase
		LACFR_08_02840	2-dehydropantoate 2-reductase
Lactobacillus helveticus	15019	HMPREF0518_1514	2-dehydropantoate 2-reductase
Lactobacillus hilgardii	15886	HMPREF0519_0482	2-dehydropantoate 2-reductase
		HMPREF0519_0985	2-dehydropantoate 2-reductase
		HMPREF0519_1181	2-dehydropantoate 2-reductase
		HMPREF0519_1186	2-dehydropantoate 2-reductase
Lactobacillus plantarum subsp. plantarum	15891	HMPREF0531_10396	2-dehydropantoate 2-reductase
		HMPREF0531_11399	2-dehydropantoate 2-reductase
		HMPREF0531_11887	2-dehydropantoate 2-reductase
Lactobacillus reuteri	15892	LAR_0338	2-dehydropantoate 2-reductase
		LAR_1750	2-dehydropantoate 2-reductase
Leptospira interrogans		LA_2190	2-dehydropantoate 2-reductase
		LA_3613	2-dehydropantoate 2-reductase
Leuconostoc lactis	107866	EY7_283_00030	2-dehydropantoate 2-reductase
		EY7_429_00010	2-dehydropantoate 2-reductase
		EY7_956_00010	2-dehydropantoate 2-reductase
Leuconostoc mesenteroides subsp. cremoris	107766	HMPREF0555_0254	2-dehydropantoate 2-reductase
		HMPREF0555_0915	2-dehydropantoate 2-reductase
Leuconostoc mesenteroides subsp. mesenteroides	100496	LEUM_0258	ketopantoate reductase
		LEUM_1477	ketopantoate reductase
Leuconostoc pseudomesenteroides	107767	LpseK3_010100004512	ketopantoate reductase
		LpseK3_010100016214	2-dehydropantoate 2-reductase
Limnochorda pilosa	110152	LIP_1485	2-dehydropantoate 2-reductase
Magnetospirillum magnetotacticum	15272	Magn03007461	COG1893: Ketopantoate reductase
Marinomonas mediterranea	103028	Marme_2063	2-dehydropantoate 2-reductase
		Marme_3625	2-dehydropantoate 2-reductase
Mariprofundus ferrooxydans		SPV1_13654	putative 2-dehydropantoate 2-reductase
Marivirga tractuosa	15989	Ftrac_2458	2-dehydropantoate 2-reductase
Methanocella paludicola	101707	MCP_2660	2-dehydropantoate 2-reductase
Methanococcus maripaludis	101832	MMP0672	Binding-protein-dependent transport systems inner membrane component:Ketopantoate reductase ApbA/PanE
Methylacidiphilum infernorum		Minf_0239	Ketopantoate reductase
Methylobacterium radiotolerans	15690	Mrad2831_0085	2-dehydropantoate 2-reductase
		Mrad2831_3569	2-dehydropantoate 2-reductase
Microlunatus phosphovorus	101784	MLP_12770	putative 2-dehydropantoate 2-reductase
Micromonospora aurantiaca	16155	Micau_0846	Ketopantoate reductase ApbA/PanE domain protein
Myroides odoratus	14945	Myrod_1337	ketopantoate reductase
Nakamurella multipartita	105858	Namu_1107	2-dehydropantoate 2-reductase
Niastella koreensis	106392	Niako_4263	ketopantoate reductase
Nitrospina gracilis		NITGR_190057	putative 2-dehydropantoate 2-reductase
Nocardiopsis dassonvillei	14626	Ndas_2408	2-dehydropantoate 2-reductase
		Ndas_4110	2-dehydropantoate 2-reductase
Nostoc sp.		all1319	hypothetical protein
Oceanithermus profundus	100410	Ocepr_0678	2-dehydropantoate 2-reductase
Oscillibacter valericigenes	101213	OBV_12990	putative oxidoreductase
Paenibacillus alvei	3343	PAV_4c05090	2-dehydropantoate 2-reductase
Paenibacillus peoriae	15541	PpeoK3_010100003735	2-dehydropantoate 2-reductase
Paenibacillus polymyxa	15309	PPT_03250	2-dehydropantoate 2-reductase
		PPT_18330	2-dehydropantoate 2-reductase
Pelobacter propionicus	103807	Ppro_2669	ketopantoate reductase
Photobacterium damselae subsp. damselae corrig.	15633	VDA_002667	2-dehydropantoate 2-reductase
Propionibacterium acidipropionici	12425	PACID_01340	2-dehydropantoate 2-reductase
		PACID_14990	2-dehydropantoate 2-reductase
		PACID_17130	Putative 2-dehydropantoate 2-reductase
		PACID_28390	2-dehydropantoate 2-reductase
Propionibacterium avidum	15671	HMPREF9153_1976	2-dehydropantoate 2-reductase
Proteus mirabilis	105697	HMPREF0693_3349	2-dehydropantoate 2-reductase
Providencia alcalifaciens	105687	PROVALCAL_00216	2-dehydropantoate 2-reductase
Pseudomonas putida	100650	PP_1351	2-dehydropantoate 2-reductase, putative
		PP_2325	ketopantoate reductase
		PP_2998	2-dehydropantoate 2-reductase, putative
Pseudomonas stutzeri	14165	PSTAB_1925	2-dehydropantoate 2-reductase
		PSTAB_3203	2-dehydropantoate 2-reductase
Pyrococcus horikoshii	100139	PH1390	2-dehydropantoate 2-reductase
Rahnella aquatilis	105701	Rahaq2_3443	2-dehydropantoate 2-reductase
		Rahaq2_4643	2-dehydropantoate 2-reductase
		Rahaq2_4736	2-dehydropantoate 2-reductase
Rhizobium etli	15573	RHE_CH01710	probable 2-dehydropantoate 2-reductase (ketopantoate reductase) protein
Rhizobium tropici	15247	RTCIAT899_CH07615	2-dehydropantoate 2-reductase
		RTCIAT899_PC09390	putative ketopantoate reductase
Rhodobacter sphaeroides	12203	RSP_1558	putative 2-dehydropantoate 2-reductase
Rhodococcus opacus	108011	ROP_13640	putative 2-dehydropantoate 2-reductase
Roseobacter denitrificans	15277	RD1_2198	2-dehydropantoate 2-reductase, putative
Roseobacter litoralis	15278	RLO149_c013310	putative ketopantoate reductase
Rubrobacter xylanophilus	100952	Rxyl_0382	2-dehydropantoate 2-reductase
		Rxyl_2991	2-dehydropantoate 2-reductase
Saccharopolyspora erythraea	13426	SACE_1860	2-dehydropantoate 2-reductase
Saccharopolyspora spinosa	15153	SspiN1_010100012429	2-dehydropantoate 2-reductase
Saccharothrix espanaensis	15066	BN6_52160	hypothetical protein
Sanguibacter keddieii	16158	Sked_06250	2-dehydropantoate 2-reductase
Selenomonas ruminantium subsp. lactilytica	103574	SELR_21690	putative 2-dehydropantoate 2-reductase
Serratia odorifera	102598	HMPREF0758_0213	2-dehydropantoate 2-reductase
		HMPREF0758_3058	2-dehydropantoate 2-reductase
Shimwellia blattae	105725	EB105725_34_00230	2-dehydropantoate 2-reductase
Sphingobium japonicum	101211	SJA_C2-03560	2-dehydropantoate 2-reductase
Sphingobium sp.	103272	SLG_28350	putative 2-dehydropantoate 2-reductase
Sphingomonas wittichii	105917	Swit_2699	2-dehydropantoate 2-reductase
		Swit_4927	2-dehydropantoate 2-reductase
Stackebrandtia nassauensis	102104	Snas_3493	2-dehydropantoate 2-reductase
		Snas_4116	2-dehydropantoate 2-reductase
Staphylococcus epidermidis	12993	SE_2009	2-dehydropantoate 2-reductase
		SE_2142	2-dehydropantoate 2-reductase
Staphylococcus saprophyticus subsp. saprophyticus	102446	SSP0153	putative 2-dehydropantoate 2-reductase
		SSP0246	putative 2-dehydropantoate 2-reductase
Starkeya novella	14993	Snov_2986	2-dehydropantoate 2-reductase
Streptococcus equinus	12553	HMPREF0819_1423	2-dehydropantoate 2-reductase
Streptomyces avermitilis	14893	SAV1833	putative oxidoreductase
		SAV5819	putative oxidoreductase
Streptomyces pristinaespiralis	13074	SSDG_04656	2-dehydropantoate 2-reductase
Streptomyces sviceus	13980	SSEG_01908	2-dehydropantoate 2-reductase
		SSEG_06162	2-dehydropantoate 2-reductase
		SSEG_10291	2-dehydropantoate 2-reductase
Streptomyces venezuelae	13096	SVEN_6662	2-dehydropantoate 2-reductase
Tetragenococcus halophilus	12172	TEH_10400	putative 2-dehydropantoate 2-reductase
		TEH_15810	putative 2-dehydropantoate 2-reductase
Thauera linaloolentis	102519	C666_17115	2-dehydropantoate 2-reductase
Thermanaerovibrio acidaminovorans		Taci_0462	2-dehydropantoate 2-reductase
Thermococcus sp.		GQS_08180	2-dehydropantoate 2-reductase
Thermodesulfobacterium commune		HL41_02520	2-dehydropantoate 2-reductase
Thermodesulfobium narugense	100082	Thena_1132	Ketopantoate reductase ApbA/PanE domain protein
Thermodesulfovibrio yellowstonii		THEYE_A1601	2-dehydropantoate 2-reductase
		THEYE_A1653	2-dehydropantoate 2-reductase
Thermoproteus neutrophilus	100436	Tneu_0313	2-dehydropantoate 2-reductase
Vibrio alginolyticus	15630	N646_1479	2-dehydropantoate 2-reductase
Vibrio ichthyoenteri	15847	VII00023_02789	2-dehydropantoate 2-reductase
Vibrio metschnikovii	103153	VIB_001896	2-dehydropantoate 2-reductase
Vibrio orientalis	15638	VIOR3934_02193	2-dehydropantoate 2-reductase
Vibrio tubiashii	15644	VITU9109_06415	2-dehydropantoate 2-reductase
Yersinia bercovieri	105717	yberc0001_14050	2-dehydropantoate 2-reductase
Yersinia rohdei	105715	yrohd0001_1240	2-dehydropantoate 2-reductase
Zimmermannella faecalis	15706	G328_02205	hypothetical protein