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Microbe : Amycolatopsis azurea

Microbe Description

NBRC No. 14573
Scientific name Amycolatopsis azurea
Synonymous name Pseudonocardia azurea
History IFO 14573 <- Kitasato Inst. (S. Omura, AM-3696)
Other culture collection No. ATCC 51273=DSM 43854=JCM 3275=NRRL 11412=VKM Ac-1418
Other No. AM-3696=FERM-P 4738=KCC A-0275
Reference
528377
Studies on bacterial cell wall inhibitors. VII. Azureomycins A and B, new antibiotics produced by Pseudonocardia azurea nov. sp. Taxonomy of the producing organism, isolation, characterization and biological properties. (J Antibiot (Tokyo). 1979)

Functional Potential >>Details

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TypePattern Component Gene CDS
Alanine racemization(NFUNC_0063)
RequireA
ALR
(NRULE_0228)
Alanine racemaseC791_1181
n-alkane hydroxylation(NFUNC_0008)
RequireB
ALKB
(NRULE_0024)
Alkane 1-monooxygenaseC791_5134
Participant 
RUBA
(NRULE_0039)
RubredoxinC791_5134
 
FDX1
(NRULE_0034)
Putative Rieske-type ferredoxinC791_3270 C791_3220 C791_6480 C791_3216 C791_5876 C791_5512
Aminoglycoside resistance (by aminoglycoside O-phosphotransferase)(NFUNC_0043)
RequireA
APH6
(NRULE_0155)
Streptomycin 6-kinaseC791_4268 C791_2139 C791_2097
C
APH7
(NRULE_0157)
Hygromycin-B 7''-O-kinaseC791_5651
Ampicillin resistance(NFUNC_0046)
RequireA
BLAA
(NRULE_0122)
Beta-lactamase class AC791_2898 C791_0605 C791_5740
Anthranilate biosynthesis(NFUNC_0038)
RequireA
GLAT
(NRULE_0142)
Glutamine amidotransferaseC791_5392
TRPE
(NRULE_0143)
Anthranilate synthase component IC791_2023
Aromatic azo compounds degradation(NFUNC_0073)
RequireA
AZOR
(NRULE_0236)
FMN-dependent NADH-azoreductaseC791_6695 C791_4092
Bacitracin resistance(NFUNC_0022)
RequireA
UPPP
(NRULE_0097)
Undecaprenyl-diphosphataseC791_6755
Beta-lactam antibiotic resistance(NFUNC_0033)
RequireA
BLAA
(NRULE_0122)
Beta-lactamase class AC791_0605 C791_2898 C791_5740
Betaine biosynthesis (from choline)(NFUNC_0049)
RequireC
CHOX
(NRULE_0178)
Choline oxidaseC791_2877
Bioplastic degradation(NFUNC_0015)
RequireB
PHAZ2
(NRULE_0080)
Poly(3-hydroxyalkanoate) depolymeraseC791_8358
Ectoine biosynthesis(NFUNC_0056)
RequireA
ECTB
(NRULE_0186)
Diaminobutyrate--2-oxoglutarate transaminaseC791_7093
ECTA
(NRULE_0187)
L-2,4-diaminobutyric acid acetyltransferaseC791_7094
ECTC
(NRULE_0188)
L-ectoine synthaseC791_7092
GABA biosynthesis(NFUNC_0066)
RequireA
GAD
(NRULE_0231)
Glutamate decarboxylaseC791_7949
Hydroxyectoine biosynthesis(NFUNC_0057)
RequireA
ECTD
(NRULE_0189)
Ectoine hydroxylaseC791_7091
Participant 
ECTB
(NRULE_0186)
Diaminobutyrate--2-oxoglutarate transaminaseC791_7093
 
ECTA
(NRULE_0187)
L-2,4-diaminobutyric acid acetyltransferaseC791_7094
 
ECTC
(NRULE_0188)
L-ectoine synthaseC791_7092
Hygromycin resistance(NFUNC_0055)
RequireA
APH7
(NRULE_0157)
Hygromycin-B 7''-O-kinaseC791_5651
Macrolide antibiotic resistance(NFUNC_0045)
RequireB
RLMA
(NRULE_0165)
23S rRNA (guanine-N(1))-methyltransferaseC791_1806
D
ERE
(NRULE_0168)
Erythromycin esteraseC791_3516 C791_3941 C791_4719
Metal-binding protein(NFUNC_0105)
RequireA
MOP
(NRULE_0322)
Putative molybdenum-binding proteinC791_2655 C791_2652 C791_1180 C791_4097
C
MODA
(NRULE_0324)
Molybdate ABC transporter substrate-binding proteinC791_2654 C791_3464 C791_6423
F
SOXR
(NRULE_0329)
Redox-sensitive transcriptional activator SoxRC791_2049 C791_2488
Molybdate transport (ABC transporter)(NFUNC_0097)
RequireA
MODA
(NRULE_0324)
Molybdate ABC transporter substrate-binding proteinC791_3464 C791_6423 C791_2654
Participant 
MODB
(NRULE_0325)
Molybdate ABC transporter permease proteinC791_2653
(R)-pantothenate biosynthesis(NFUNC_0030)
RequireA
PAND
(NRULE_0115)
Aspartate 1-decarboxylaseC791_0704
PANB
(NRULE_0116)
3-methyl-2-oxobutanoate hydroxymethyltransferaseC791_0581
PANE
(NRULE_0117)
2-dehydropantoate 2-reductaseC791_3906
PANC
(NRULE_0118)
Pantothenate synthetaseC791_0703
Penicillin resistance(NFUNC_0047)
RequireA
BLAA
(NRULE_0122)
Beta-lactamase class AC791_2898 C791_0605 C791_5740
Phenol degradation(NFUNC_0028)
RequireB
PHEA1
(NRULE_0083)
Aromatic ring hydroxylaseC791_0274 C791_5126
Participant 
FDR1
(NRULE_0032)
Oxygenase electron transfer componentC791_7539 C791_3685 C791_5510 C791_5873 C791_8049 C791_8066 C791_0721
 
FDX1
(NRULE_0034)
Putative Rieske-type ferredoxinC791_5876 C791_6480 C791_3216 C791_3220 C791_3270 C791_5512
 
FADR1
(NRULE_0101)
NADH-dependent flavin reductaseC791_3697 C791_5880 C791_1272 C791_1374 C791_5518 C791_5125
Phytic acid hydrolysis(NFUNC_0085)
RequireA
PHYT
(NRULE_0258)
3-phytaseC791_2033
Pyrroloquinoline quinone biosynthesis(NFUNC_0020)
RequireA
PQQC
(NRULE_0092)
Pyrroloquinoline-quinone synthaseC791_3107
Participant 
PQQB
(NRULE_0091)
Coenzyme PQQ synthesis protein BC791_3110
 
PQQE
(NRULE_0094)
Coenzyme PQQ synthesis protein EC791_3109
Streptomycin resistance(NFUNC_0054)
RequireC
APH6
(NRULE_0155)
Streptomycin 6-kinaseC791_2139 C791_2097 C791_4268
Trehalose biosynthesis (from NDP-glucose and glucose-6-phosphate)(NFUNC_0031)
RequireA
TPS
(NRULE_0119)
Trehalose-phosphate synthaseC791_7147 C791_1271
TPP
(NRULE_0120)
Trehalose-6-phosphate phosphataseC791_7148
Uptake of osmoprotectant(NFUNC_0061)
RequireB
EHUB
(NRULE_0216)
Ectoine ABC transporter substrate-binding proteinC791_3004
EHUC
(NRULE_0217)
Ectoine ABC transporter permease proteinC791_3003
EHUD
(NRULE_0218)
Ectoine ABC transporter permease proteinC791_3002
EHUA
(NRULE_0219)
Ectoine ABC transporter ATP-binding proteinC791_3001
C
BCCT
(NRULE_0220)
BCCT family transporterC791_3498
Vancomycin resistance (via D-Ala-D-Lac precursor)(NFUNC_0089)
RequireA
VANA
(NRULE_0265)
D-alanine--D-lactate ligaseC791_3573
VANH
(NRULE_0266)
D-specific alpha-keto acid dehydrogenaseC791_3572
VANX
(NRULE_0267)
D-alanyl-D-alanine dipeptidaseC791_3574
Vitamin B6 biosynthesis (PdxS/PdxT pathway)(NFUNC_0059)
RequireA
PDXS
(NRULE_0206)
Pyridoxal biosynthesis lyase PdxSC791_3972
PDXT
(NRULE_0207)
Glutamine amidotransferase subunit PdxTC791_3964

Genomic Overview

BioProject IDPRJNA175934
Locus_tag
INSDC entriesANMG01000000
Sequence statusWGS
Current status
Contig number154
Size(bp) 9,223,451
Gene 8,603
Finishing goal
Assembly methodCLC NGS Cell v. 5.5
Coverage190.0x
Technology
  • Illumina HiSeq
Reference

Data Download

Genomic nucleotide sequence Nucleotide sequence of the coding regions Translation of the coding sequneces List of genes / ORFs
FASTA
gz
FASTA
gz
FASTA
gz
TSV
uncompressed
2.6 MB 2.5 MB 1.7 MB 628.9 KB