Rule : 3-oxoadipate CoA-transferase subunit A (PCAI)

Rule Description

ID	NRULE_0072
Rule name	PCAI
Created	2012-10-23
Protein name	Protein name Full 3-oxoadipate CoA-transferase subunit A EC EC 2.8.3.6 Synonym Full Beta-ketoadipate--succinyl-coenzyme A transferase
Gene name	pcaI, catI
Rule Trigger	BLASTP; Q01103; hit=1; score=610; pid=50ANDTIGRFAMs; TIGR02429; hit=1 OR TIGRFAMs; TIGR02429; hit=1ANDBLASTP; Q0SH28; hit=1; score=740; pid=60
Cross Reference	Gene Ontology GO GO:0047569, F:3-oxoadipate CoA-transferase activity, IEA:EC GO:0042952, P:beta-ketoadipate pathway, IEA:UniProtKB-UniPathway Phylogenomic databases eggNOG COG1788, - KO K01031, - Enzyme and pathway databases UniPathway UPA00157, UER00262 Family and domain databases InterPro IPR012792, 3-oxoacid_CoA-transf_A IPR004165, CoA_trans_fam_I IPR004163, CoA_transf_BS Pfam PF01144, CoA_trans, 1 SMART SM00882, CoA_trans, 1 TIGRFAMs TIGR02429, pcaI_scoA_fam, 1 PROSITE PS01273, COA_TRANSF_1, 1
Feature	Not assigned
General annotation	Catalytic activity Succinyl-CoA + 3-oxoadipate = succinate + 3- oxoadipyl-CoA Pathway Aromatic compound metabolism; beta-ketoadipate pathway; acetyl-CoA and succinyl-CoA from 3-oxoadipate: step 1/2 Subunit structure Heterodimer Sequence similarities Belongs to the 3-oxoacid CoA-transferase subunit A family
Reference	Q01103 Pseudomonas putida (Arthrobacter siderocapsulatus). 1624453 Characterization of the genes encoding beta-ketoadipate: succinyl-coenzyme A transferase in Pseudomonas putida. (J Bacteriol. 1992) Q43973 Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1). 8063101 Contrasting patterns of evolutionary divergence within the Acinetobacter calcoaceticus pca operon. (Gene. 1994) Q0SH28 Rhodococcus jostii (strain RHA1). 15937168 Catabolism of benzoate and phthalate in Rhodococcus sp. strain RHA1: redundancies and convergence. (J Bacteriol. 2005)

Related Function

Function name
Catechol degradation (beta-ketoadipate pathway)
Chlorocatechol degradation (beta-ketoadipate pathway)
Protocatechuate degradation (beta-ketoadipate pathway)

CDS


Scientific name	NBRC No.	CDS	Product name
Acaricomes phytoseiuli	107788	C501_10145	succinyl-CoA:3-ketoacid-CoA transferase
Acidiphilium multivorum	100883	ACMV_20870	3-oxoadipate CoA-transferase subunit A
Acinetobacter radioresistens	102413	ACRAD_20_00070	3-oxoadipate CoA-transferase subunit A
Acinetobacter radioresistens	102413	ACRAD_31_00470	acyl-CoA-transferase subunit A
Acinetobacter sp.	100985	ACT4_036_01110	3-oxoadipate CoA-transferase subunit A
		ACT4_038_00410	3-oxoadipate CoA-transferase subunit A
		ACT4_064_00090	acyl-CoA-transferase subunit A
Actinomadura atramentaria	14695	G339_07850	succinyl-CoA:3-ketoacid-CoA transferase
Actinoplanes missouriensis	102363	AMIS_42660	putative 3-oxoadipate CoA transferase subunit A
Arthrobacter globiformis	12137	ARGLB_036_00450	3-oxoadipate CoA-transferase alpha subunit
Arthrobacter globiformis	12137	ARGLB_098_00140	3-oxoadipate CoA-transferase alpha subunit
Azorhizobium caulinodans	14845	AZC_0994	3-oxoadipate CoA-transferase subunit A
Brevibacterium linens	12170	BlinB_010200015292	3-oxoacid CoA-transferase, A subunit
Catenulispora acidiphila	102108	Caci_4338	3-oxoacid CoA-transferase, A subunit
		Caci_4892	3-oxoacid CoA-transferase, A subunit
		Caci_7914	3-oxoacid CoA-transferase, A subunit
Cellulomonas fimi	15513	Celf_2564	3-oxoacid CoA-transferase, A subunit
Cellulomonas fimi	15513	Celf_3005	3-oxoacid CoA-transferase, A subunit
Corynebacterium callunae	15359	H924_10055	3-oxoadipate CoA-transferase subunit alpha
Corynebacterium efficiens	100395	CE2293	putative 3-oxoadipate CoA-transferase alpha chain
Corynebacterium glutamicum	12168	Cgl2390	Acyl-CoA:acetate CoA transferase alpha subunit
Corynebacterium glutamicum	12153	KIQ_00550	hypothetical protein
Cupriavidus metallidurans	102507	Rmet_3667	3-oxoacid CoA-transferase, subunit A
Cupriavidus metallidurans	102507	Rmet_5059	acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit
Enterobacter aerogenes	13534	EAE_18170	acetyl-CoA:acetoacetyl-CoA transferase alpha subunit
Escherichia fergusonii	102419	EFER_1636	3-oxoadipate CoA-transferase subunit A (Beta-ketoadipate:succinyl-CoA transferase subunit A)
Geodermatophilus obscurus	13315	Gobs_3086	3-oxoacid CoA-transferase, A subunit
Geodermatophilus obscurus	13315	Gobs_4337	3-oxoacid CoA-transferase, A subunit
Gordonia aichiensis	108223	GOACH_07_01180	putative succinyl-CoA--3-ketoacid CoA-transferase alpha subunit
Gordonia alkanivorans	16433	GOALK_047_00170	putative succinyl-CoA--3-ketoacid CoA-transferase alpha subunit
Gordonia amarae	15530	GOAMR_78_00300	3-oxoadipate CoA-transferase subunit A
Gordonia amicalis	100051	GOAMI_40_00520	3-oxoadipate CoA-transferase alpha subunit
Gordonia bronchialis	16047	Gbro_4164	3-oxoacid CoA-transferase, A subunit
Gordonia namibiensis	108229	GONAM_20_00330	putative succinyl-CoA--3-ketoacid coenzyme A transferase
Gordonia namibiensis	108229	GONAM_25_00260	3-oxoadipate CoA-transferase alpha subunit
Gordonia otitidis	100426	GOOTI_181_00020	putative succinyl-CoA--3-ketoacid CoA-transferase alpha subunit
Gordonia polyisoprenivorans	16320	GOPIP_011_00710	3-oxoadipate CoA-transferase alpha subunit
Gordonia polyisoprenivorans	16320	GOPIP_064_00780	putative succinyl-CoA--3-ketoacid CoA-transferase alpha subunit
Gordonia rhizosphera	16068	GORHZ_026_00050	putative succinyl-CoA--3-ketoacid CoA-transferase alpha subunit
		GORHZ_062_00520	succinyl-CoA--3-ketoacid CoA-transferase alpha subunit
		GORHZ_209_00370	3-oxoadipate CoA-transferase alpha subunit
Gordonia rubripertincta	101908	GORBP_060_00720	3-oxoadipate CoA-transferase alpha subunit
Gordonia sihwensis	108236	GSI01S_09_00310	3-oxoadipate CoA-transferase subunit A
Gordonia sputi	100414	GOSPT_141_00280	succinyl-CoA--3-ketoacid CoA-transferase alpha subunit
Gordonia terrae	100016	GOTRE_039_02310	putative succinyl-CoA--3-ketoacid CoA-transferase alpha subunit
Gordonia terrae	100016	GOTRE_125_00200	3-oxoadipate CoA-transferase alpha subunit
Hylemonella gracilis	14920	HGR_08779	3-oxoacid CoA-transferase subunit A
Intrasporangium calvum	12989	Intca_0851	3-oxoadipate CoA-transferase alpha subunit
Kineosphaera limosa	100340	KILIM_018_00100	3-oxoadipate CoA-transferase subunit A
Klebsiella pneumoniae	14438	KPR_2771
Klebsiella pneumoniae subsp. rhinoscleromatis	105682	HMPREF0484_4169	3-oxoacid CoA-transferase, A subunit
Kocuria rhizophila	103217	KRH_06090	3-oxoadipate CoA-transferase subunit A
Labrenzia aggregata	16684	SIAM614_04865	3-oxoadipate CoA-transferase, alpha subunit
Magnetospirillum magnetotacticum	15272	Magn03003119	COG1788: Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit
Micrococcus luteus	3333	Mlut_07610	3-oxoacid CoA-transferase, A subunit
Microlunatus phosphovorus	101784	MLP_35070	succinyl-CoA--3-ketoacid CoA-transferase subunit A
Nakamurella multipartita	105858	Namu_1113	3-oxoacid CoA-transferase, A subunit
Ochrobactrum anthropi	15819	Oant_3720	3-oxoacid CoA-transferase, A subunit
Ochrobactrum intermedium	15820	OINT_2000806	3-oxoacid CoA-transferase, A subunit
Pseudomonas putida	100650	PP_3951	3-oxoadipate CoA-transferase, subunit A
Renibacterium salmoninarum	15589	RSal33209_0553	3-ketoacid-CoA transferase, alpha subunit
Rhizobium etli	15573	RHE_PE00201	3-oxoadipate CoA-transferase subunit A protein
Rhizobium tropici	15247	RTCIAT899_PC07420	3-oxoadipate CoA-transferase subunit A
Rhodococcus erythropolis	100887	RER_12090	probable succinyl-CoA--3-ketoacid CoA-transferase alpha subunit
Rhodococcus erythropolis	100887	RER_52850	probable 3-oxoadipate CoA-transferase alpha subunit
Rhodococcus opacus	108011	ROP_10500	putative 3-oxoadipate CoA-transferase alpha subunit
Rhodococcus opacus	108011	ROP_37640	succinyl-CoA--3-ketoacid CoA-transferase alpha subunit
Saccharomonospora azurea	14651	SacazDRAFT_00375	3-oxoacid CoA-transferase, A subunit
Saccharomonospora glauca	14831	SacglDRAFT_02098	3-oxoacid CoA-transferase, A subunit
Saccharomonospora viridis	12207	Svir_07030	3-oxoacid CoA-transferase, A subunit
Saccharopolyspora spinosa	15153	SspiN1_010100037389	3-oxoadipate CoA-transferase subunit A
Shimwellia blattae	105725	EB105725_23_00520	acetate CoA-transferase subunit alpha
Sphingomonas wittichii	105917	Swit_4338	3-oxoacid CoA-transferase, A subunit
Sporichthya polymorpha	12702	Spopo_31_18160	3-oxoacid CoA-transferase, A subunit
Streptomyces avermitilis	14893	SAV1700	putative 3-oxoadipate CoA-transferase subunit A
Streptomyces ghanaensis	15414	SSFG_00968	succinyl CoA:3-oxoadipate CoA transferase alpha subunit
		SSFG_01806	CoA transferase subunit A
		SSFG_07167	3-oxoadipate CoA-transferase subunit A
Streptomyces sviceus	13980	SSEG_08945	succinyl CoA:3-oxoadipate CoA transferase alpha subunit
Thermomonospora curvata	15933	Tcur_2343	3-oxoacid CoA-transferase, A subunit
Tsukamurella paurometabola	16120	Tpau_0620	3-oxoacid CoA-transferase, A subunit