BLAST table : Megalo_00140

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q9F828_9ACTO
(Q9F828)		 
[query] 1 - 3201 (3201)
[subject] 1 - 3201 (3201)
 0.0 6249   100% Megalomicin 6-deoxyerythronolide B synthase 3 megAIII Micromonospora megalomicea subsp. nigra
2
 A4F7P1_SACEN
(A4F7P1)		 
[query] 1 - 3198 (3201)
[subject] 1 - 3168 (3171)
 0.0 4573   75% EryAIII Erythromycin polyketide synthase modules 5 and 6 eryAIII
SACE_0724		 Saccharopolyspora erythraea (strain NRRL 23338)
3
 Q5UNP4_SACER
(Q5UNP4)		 
[query] 1 - 3198 (3201)
[subject] 1 - 3168 (3171)
 0.0 4573   75% EryAIII eryAIII Saccharopolyspora erythraea
Streptomyces erythraeus
4
 ERYA3_SACER
(Q03133)		 
[query] 1 - 3198 (3201)
[subject] 1 - 3169 (3172)
 0.0 4408   74% Erythronolide synthase, modules 5 and 6
6-deoxyerythronolide B synthase III
DEBS 3
ORF 3		 eryA Saccharopolyspora erythraea
Streptomyces erythraeus		 2.3.1.94
5
 Q83X71_STRRO
(Q83X71)		 
[query] 10 - 3199 (3201)
[subject] 22 - 3294 (3295)
 0.0 3382   60% Lankamycin synthase LkmAIII lkmAIII Streptomyces rochei
Streptomyces parvullus
6
 Q5Y9G6_9ACTO
(Q5Y9G6)		 
[query] 9 - 3195 (3201)
[subject] 2 - 3191 (3195)
 0.0 3121   59% Polyketide synthase modules 5 and 6 eryAIII Aeromicrobium erythreum
7
 Q9F830_9ACTO
(Q9F830)		 Jump to Megalo_00120 
[query] 34 - 2920 (3201)
[subject] 552 - 3465 (3546)
(4 hsp)		 0.0 2589   57% Megalomicin 6-deoxyerythronolide B synthase 1 megAI Micromonospora megalomicea subsp. nigra
8
 ERYA1_SACER
(Q03131)		 
[query] 18 - 2920 (3201)
[subject] 477 - 3407 (3491)
(4 hsp)		 0.0 2496   52% Erythronolide synthase, modules 1 and 2
6-deoxyerythronolide B synthase I
DEBS 1
ORF 1		 eryA Saccharopolyspora erythraea
Streptomyces erythraeus		 2.3.1.94
9
 A4F7N8_SACEN
(A4F7N8)		 
[query] 18 - 2920 (3201)
[subject] 530 - 3461 (3545)
(4 hsp)		 0.0 2494   53% EryAI Erythromycin polyketide synthase modules 1 and 2 eryAI
SACE_0721		 Saccharopolyspora erythraea (strain NRRL 23338)
10
 Q5UNP6_SACER
(Q5UNP6)		 
[query] 18 - 2920 (3201)
[subject] 530 - 3461 (3545)
(4 hsp)		 0.0 2494   53% EryAI eryAI Saccharopolyspora erythraea
Streptomyces erythraeus
11
 Q3S869_9ACTO
(Q3S869)		 Jump to Conca_00080 
[query] 5 - 2916 (3201)
[subject] 2 - 3171 (5006)
(6 hsp)		 0.0 2304   48% Modular polyketide synthase Streptomyces neyagawaensis
12
 B4VB12_9ACTO
(B4VB12)		 
[query] 7 - 2916 (3201)
[subject] 2 - 3119 (3203)
 0.0 2302   48% Polyketide synthase type I SSAG_04922 Streptomyces sp. Mg1
13
 C9YYI3_STRSW
(C9YYI3)		 
[query] 5 - 2916 (3201)
[subject] 2 - 3172 (5001)
(5 hsp)		 0.0 2296   48% Putative type I polyketide synthase SCAB_83921 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
14
 Q9KIV4_STRAT
(Q9KIV4)		 
[query] 39 - 2920 (3201)
[subject] 1062 - 4065 (4150)
(5 hsp)		 0.0 2289   50% 8,8a-deoxyoleandolide synthase 1 oleAI Streptomyces antibioticus
15
 B1W487_STRGG
(B1W487)		 
[query] 8 - 2916 (3201)
[subject] 4 - 3096 (3188)
(2 hsp)		 0.0 2268   47% Putative type-I PKS pks1-3
SGR_6075		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
16
 Q83X69_STRRO
(Q83X69)		 
[query] 39 - 2940 (3201)
[subject] 588 - 3575 (3651)
(4 hsp)		 0.0 2263   51% Lankamycin synthase LkmAI lkmAI Streptomyces rochei
Streptomyces parvullus
17
 Q93HJ2_STRAW
(Q93HJ2)		 Jump to Oligo_00110 
[query] 16 - 2926 (3201)
[subject] 12 - 3074 (4685)
(6 hsp)		 0.0 2236   48% Modular polyketide synthase olmA6
SAV2896
SAV_2896		 Streptomyces avermitilis
18
 D5ZU01_9ACTO
(D5ZU01)		 
[query] 7 - 2920 (3201)
[subject] 29 - 3009 (4790)
(4 hsp)		 0.0 2225   47% Nodular polyketide synthase SSFG_00090 Streptomyces ghanaensis ATCC 14672
19
 Q93H83_STRAW
(Q93H83)		 
[query] 9 - 3197 (3201)
[subject] 5 - 3334 (3352)
 0.0 2210   45% Modular polyketide synthase pteA5
SAV415
SAV_415		 Streptomyces avermitilis
20
 D2CKM3_PSEAH
(D2CKM3)		 
[query] 1 - 2920 (3201)
[subject] 1 - 3087 (3175)
(3 hsp)		 0.0 2196   48% CppB cppB Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
21
 E0KRC6_STRVO
(E0KRC6)		 
[query] 39 - 2919 (3201)
[subject] 2931 - 5900 (11118)
(10 hsp)		 0.0 2179   47% Beta-ketoacyl synthase StrviDRAFT_5203 Streptomyces violaceusniger Tu 4113
22
 E0KBI2_STRVO
(E0KBI2)		 
[query] 39 - 2920 (3201)
[subject] 1760 - 4851 (4930)
(5 hsp)		 0.0 2176   46% Mycocerosate synthase., 6-deoxyerythronolide-B synthase StrviDRAFT_0197 Streptomyces violaceusniger Tu 4113 2.3.1.111

2.3.1.94
23
 E0KBI5_STRVO
(E0KBI5)		 
[query] 7 - 2916 (3201)
[subject] 1 - 3117 (3205)
(2 hsp)		 0.0 2156   46% Acyl transferase StrviDRAFT_0200 Streptomyces violaceusniger Tu 4113
24
 Q53840_SORCE
(Q53840)		 Jump to Soraph_00080 
[query] 37 - 2920 (3201)
[subject] 3669 - 6756 (8817)
(9 hsp)		 0.0 2155   45% Soraphen polyketide synthase B sorB Sorangium cellulosum
Polyangium cellulosum
25
 A0ACI0_STRAM
(A0ACI0)		 
[query] 39 - 3196 (3201)
[subject] 3064 - 6328 (6333)
(4 hsp)		 0.0 2123   44% Putative modular polyketide synthase SAMR0474 Streptomyces ambofaciens ATCC 23877
26
 Q1WEK7_9ACTO
(Q1WEK7)		 
[query] 39 - 2926 (3201)
[subject] 2954 - 5936 (7968)
(5 hsp)		 0.0 2120   47% Polyketide synthase merC Streptomyces sp. NRRL 30748
27
 Q9ALM4_9PSEU
(Q9ALM4)		 Jump to Spino_00190 
[query] 8 - 2970 (3201)
[subject] 3 - 3141 (3170)
 0.0 2117   46% Polyketide synthase extender modules 3-4 spnC Saccharopolyspora spinosa
28
 F1CLA9_9ACTO
(F1CLA9)		 
[query] 39 - 2932 (3201)
[subject] 3324 - 6390 (9498)
(9 hsp)		 0.0 2116   46% ScnS2 scnS2 Streptomyces chattanoogensis
29
 E8S0C1_MICSL
(E8S0C1)		 
[query] 36 - 2916 (3201)
[subject] 1538 - 4621 (4706)
(4 hsp)		 0.0 2112   47% 6-deoxyerythronolide-B synthase., (Acyl-carrier-protein) S-acetyltransferase ML5_5894 Micromonospora sp. (strain L5) 2.3.1.38

2.3.1.94
30
 Q5Y9G4_9ACTO
(Q5Y9G4)		 
[query] 39 - 2922 (3201)
[subject] 512 - 3433 (3528)
(4 hsp)		 0.0 2104   50% Polyketide synthase modules 1 and 2 eryAI Aeromicrobium erythreum
31
 Q68BG5_STRHA
(Q68BG5)		 Jump to Halsto_00010 
[query] 39 - 2983 (3201)
[subject] 1020 - 4179 (4194)
(6 hsp)		 0.0 2101   44% Type I polyketide synthase hlsA Streptomyces halstedii
32
 D9T6W8_MICAI
(D9T6W8)		 
[query] 36 - 2916 (3201)
[subject] 1542 - 4625 (4710)
(4 hsp)		 0.0 2100   47% Beta-ketoacyl synthase Micau_2468 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
33
 D3Y1I3_9ACTO
(D3Y1I3)		 
[query] 37 - 2916 (3201)
[subject] 1022 - 3996 (5828)
(8 hsp)		 0.0 2097   45% TamAI Streptomyces sp. 307-9
34
 Q9EWA1_9ACTO
(Q9EWA1)		 Jump to Pimar_00070 
[query] 39 - 2920 (3201)
[subject] 3332 - 6382 (9507)
(10 hsp)		 0.0 2097   46% PimS2 protein pimS2 Streptomyces natalensis
35
 F1DI31_9ACTO
(F1DI31)		 
[query] 37 - 2916 (3201)
[subject] 1022 - 3997 (5829)
(8 hsp)		 0.0 2086   45% TrdAI Streptomyces sp. SCSIO1666
36
 D1GLV9_9ACTO
(D1GLV9)		 Jump to Strply_00310 
[query] 39 - 2916 (3201)
[subject] 1069 - 4165 (6171)
(9 hsp)		 0.0 2085   46% Polyketide synthase type I slgA1 Streptomyces lydicus
37
 D7P614_CHOCO
(D7P614)		 
[query] 38 - 2920 (3201)
[subject] 16 - 3110 (6610)
(6 hsp)		 0.0 2076   44% TugD tugD Chondromyces crocatus
38
 D7BRE1_STRBB
(D7BRE1)		 
[query] 39 - 2920 (3201)
[subject] 1975 - 5043 (5139)
(5 hsp)		 0.0 2064   45% Modular polyketide synthase SBI_01983 Streptomyces bingchenggensis (strain BCW-1)
39
 Q93NX9_9ACTO
(Q93NX9)		 Jump to Amph_00040 
[query] 37 - 2920 (3201)
[subject] 1770 - 4834 (9510)
(11 hsp)		 0.0 2040   44% AmphI amphI Streptomyces nodosus
40
 D9T6X1_MICAI
(D9T6X1)		 
[query] 8 - 2920 (3201)
[subject] 3 - 3081 (3165)
 0.0 2029   46% Beta-ketoacyl synthase Micau_2471 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
41
 E8S0B8_MICSL
(E8S0B8)		 
[query] 8 - 2920 (3201)
[subject] 3 - 3081 (3165)
 0.0 2027   46% Beta-ketoacyl synthase ML5_5891 Micromonospora sp. (strain L5)
42
 A0FCL3_STRVO
(A0FCL3)		 Jump to Merid_00040 
[query] 37 - 2926 (3201)
[subject] 2948 - 5938 (11604)
(11 hsp)		 0.0 2026   46% MerC merC Streptomyces violaceoniger
43
 D9WQ82_9ACTO
(D9WQ82)		 
[query] 8 - 2382 (3201)
[subject] 4 - 2458 (3199)
(4 hsp)		 0.0 2023   50% Erythronolide synthase, modules 1 and 2 SSOG_05756 Streptomyces himastatinicus ATCC 53653
44
 C9YYI1_STRSW
(C9YYI1)		 
[query] 9 - 2386 (3201)
[subject] 4 - 2464 (4970)
(7 hsp)		 0.0 2023   51% Putative type I polyketide synthase SCAB_83901 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
45
 E0D202_9ACTO
(E0D202)		 Jump to FD891_00010 
[query] 39 - 2393 (3201)
[subject] 1038 - 3425 (7480)
(10 hsp)		 0.0 2018   51% Polyketide synthase gfsA Streptomyces graminofaciens
46
 Q9L4X3_9ACTO
(Q9L4X3)		 Jump to Nysta_00050 
[query] 37 - 2920 (3201)
[subject] 1811 - 4879 (9477)
(10 hsp)		 0.0 2017   45% NysI nysI Streptomyces noursei
47
 D5ZU03_9ACTO
(D5ZU03)		 
[query] 39 - 2437 (3201)
[subject] 1474 - 3828 (4652)
(6 hsp)		 0.0 2014   51% Type I modular polyketide synthase SSFG_00092 Streptomyces ghanaensis ATCC 14672
48
 Q8GBX6_SORCE
(Q8GBX6)		 
[query] 5 - 2930 (3201)
[subject] 2 - 3139 (5017)
(5 hsp)		 0.0 2013   44% Polyketide synthase spiH Sorangium cellulosum
Polyangium cellulosum
49
 Q3S864_9ACTO
(Q3S864)		 Jump to Conca_00060 
[query] 9 - 2383 (3201)
[subject] 4 - 2457 (4970)
(6 hsp)		 0.0 2011   51% Nodular polyketide synthase Streptomyces neyagawaensis
50
 A4F5C7_SORCE
(A4F5C7)		 
[query] 16 - 2930 (3201)
[subject] 1 - 3127 (5005)
(5 hsp)		 0.0 2003   44% Polyketide synthase spiH Sorangium cellulosum
Polyangium cellulosum
51
 Q9L4W4_9ACTO
(Q9L4W4)		 Jump to Nysta_00140 
[query] 9 - 2382 (3201)
[subject] 12 - 2464 (3192)
(4 hsp)		 0.0 1998   50% NysB nysB Streptomyces noursei
52
 Q3S865_9ACTO
(Q3S865)		 Jump to Conca_00050 
[query] 39 - 2926 (3201)
[subject] 58 - 3194 (4825)
(4 hsp)		 0.0 1988   46% Modular polyketide synthase Streptomyces neyagawaensis
53
 A0FCL2_STRVO
(A0FCL2)		 Jump to Merid_00030 
[query] 37 - 2385 (3201)
[subject] 1732 - 4191 (7178)
(10 hsp)		 0.0 1988   49% MerB merB Streptomyces violaceoniger
54
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 37 - 2385 (3201)
[subject] 1727 - 4144 (7102)
(9 hsp)		 0.0 1983   49% Polyketide synthase merB Streptomyces sp. NRRL 30748
55
 E0KRC7_STRVO
(E0KRC7)		 
[query] 37 - 2385 (3201)
[subject] 189 - 2605 (5559)
(7 hsp)		 0.0 1982   50% Beta-ketoacyl synthase StrviDRAFT_5204 Streptomyces violaceusniger Tu 4113
56
 A0FCL1_STRVO
(A0FCL1)		 Jump to Merid_00020 
[query] 39 - 2437 (3201)
[subject] 1067 - 3437 (5721)
(8 hsp)		 0.0 1981   50% MerA merA Streptomyces violaceoniger
57
 D7P5Z5_SORCE
(D7P5Z5)		 
[query] 46 - 2917 (3201)
[subject] 1 - 3165 (6663)
(7 hsp)		 0.0 1973   45% TgaC tgaC Sorangium cellulosum
Polyangium cellulosum
58
 D1GLV8_9ACTO
(D1GLV8)		 Jump to Strply_00300 
[query] 7 - 2383 (3201)
[subject] 19 - 2537 (3479)
(4 hsp)		 0.0 1972   50% Polyketide synthase type I slgA2 Streptomyces lydicus
59
 D6C474_9ACTO
(D6C474)		 Jump to Meili_00270 
[query] 8 - 2936 (3201)
[subject] 5 - 3088 (5277)
(4 hsp)		 0.0 1966   44% Modular polyketide synthase meiA4 Streptomyces nanchangensis
60
 Q5SFB4_STRBI
(Q5SFB4)		 Jump to Chalc_00210 
[query] 39 - 2382 (3201)
[subject] 1063 - 3435 (4441)
(6 hsp)		 0.0 1964   51% Polyketide synthase subunit chmGI Streptomyces bikiniensis
61
 C9YYI0_STRSW
(C9YYI0)		 
[query] 39 - 2928 (3201)
[subject] 27 - 3177 (4799)
(4 hsp)		 0.0 1964   46% Putative type I polyketide synthase SCAB_83891 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
62
 E0KN03_STRVO
(E0KN03)		 
[query] 39 - 2437 (3201)
[subject] 1018 - 3390 (3735)
(5 hsp)		 0.0 1962   50% 6-deoxyerythronolide-B synthase., Mycocerosate synthase StrviDRAFT_3962 Streptomyces violaceusniger Tu 4113 2.3.1.111

2.3.1.94
63
 F1DI32_9ACTO
(F1DI32)		 
[query] 4 - 2386 (3201)
[subject] 11 - 2469 (3378)
(5 hsp)		 0.0 1961   48% TrdAII Streptomyces sp. SCSIO1666
64
 Q93H84_STRAW
(Q93H84)		 
[query] 39 - 2920 (3201)
[subject] 1543 - 4556 (6145)
(6 hsp)		 0.0 1959   45% Modular polyketide synthase pteA4
SAV416
SAV_416		 Streptomyces avermitilis
65
 Q1WEK9_9ACTO
(Q1WEK9)		 
[query] 39 - 2437 (3201)
[subject] 1061 - 3433 (5712)
(8 hsp)		 0.0 1959   51% Polyketide synthase merA Streptomyces sp. NRRL 30748
66
 Q93NW7_9ACTO
(Q93NW7)		 Jump to Amph_00160 
[query] 1 - 2388 (3201)
[subject] 1 - 2468 (3190)
(4 hsp)		 0.0 1955   48% AmphB amphB Streptomyces nodosus
67
 F1ADL9_9ACTO
(F1ADL9)		 
[query] 7 - 2392 (3201)
[subject] 1 - 2523 (5145)
(9 hsp)		 0.0 1955   49% BafAII Streptomyces lohii
68
 D7C2C3_STRBB
(D7C2C3)		 
[query] 37 - 2823 (3201)
[subject] 1869 - 4850 (4868)
(5 hsp)		 0.0 1952   45% Modular polyketide synthase pks3-4
SBI_00656		 Streptomyces bingchenggensis (strain BCW-1)
69
 D3Y1I4_9ACTO
(D3Y1I4)		 
[query] 7 - 2386 (3201)
[subject] 1 - 2456 (3365)
(5 hsp)		 0.0 1950   48% TamAII Streptomyces sp. 307-9
70
 Q8KPW5_9ACTO
(Q8KPW5)		 
[query] 39 - 2418 (3201)
[subject] 1008 - 3420 (4387)
(7 hsp)		 0.0 1938   50% Putative type I polyketide synthase gerSI Streptomyces sp. KCTC 0041BP
71
 E0KBI3_STRVO
(E0KBI3)		 
[query] 8 - 2916 (3201)
[subject] 4 - 3107 (4750)
(3 hsp)		 0.0 1936   43% 6-methylsalicylic acid synthase., 6-deoxyerythronolide-B synthase StrviDRAFT_0198 Streptomyces violaceusniger Tu 4113 2.3.1.165

2.3.1.94
72
 B4VAJ6_9ACTO
(B4VAJ6)		 
[query] 39 - 2418 (3201)
[subject] 1016 - 3425 (3605)
(5 hsp)		 0.0 1936   50% Polyketide synthase subunit SSAG_04835 Streptomyces sp. Mg1
73
 E0KBI4_STRVO
(E0KBI4)		 
[query] 7 - 2916 (3201)
[subject] 2 - 3111 (8275)
(8 hsp)		 0.0 1935   43% Beta-ketoacyl synthase StrviDRAFT_0199 Streptomyces violaceusniger Tu 4113
74
 Q9KIV3_STRAT
(Q9KIV3)		 
[query] 7 - 2388 (3201)
[subject] 1 - 2478 (3816)
(4 hsp)		 0.0 1934   49% 8,8a-deoxyoleandolide synthase 2 oleAII Streptomyces antibioticus
75
 F1ADM1_9ACTO
(F1ADM1)		 
[query] 7 - 2389 (3201)
[subject] 27 - 2558 (3511)
(4 hsp)		 0.0 1927   49% BafAIV Streptomyces lohii
76
 E2Q518_STRCL
(E2Q518)		 
[query] 2 - 2388 (3201)
[subject] 10 - 2590 (3596)
(4 hsp)		 0.0 1927   48% Modular polyketide synthase SCLAV_0012 Streptomyces clavuligerus ATCC 27064
77
 Q6W5P9_9ACTO
(Q6W5P9)		 Jump to FR008_00170 
[query] 8 - 2382 (3201)
[subject] 3 - 2486 (5541)
(8 hsp)		 0.0 1924   49% FscB fscB Streptomyces sp. FR-008
78
 Q5SFB2_STRBI
(Q5SFB2)		 Jump to Chalc_00230 
[query] 2 - 2382 (3201)
[subject] 3 - 2415 (3788)
(5 hsp)		 0.0 1922   50% Polyketide synthase subunit chmGIII Streptomyces bikiniensis
79
 B4VBW0_9ACTO
(B4VBW0)		 
[query] 39 - 2927 (3201)
[subject] 179 - 3238 (10873)
(11 hsp)		 0.0 1917   44% Polyketide synthase type I SSAG_05337 Streptomyces sp. Mg1
80
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 36 - 2920 (3201)
[subject] 1814 - 4875 (14130)
(19 hsp)		 0.0 1914   41% Type I modular polyketide synthase mlsB
MUP032c		 Mycobacterium ulcerans (strain Agy99)
81
 F1ADL8_9ACTO
(F1ADL8)		 
[query] 39 - 2921 (3201)
[subject] 586 - 3697 (4884)
(8 hsp)		 0.0 1913   44% BafAI Streptomyces lohii
82
 Q0ILD1_9ACTO
(Q0ILD1)		 
[query] 39 - 2383 (3201)
[subject] 1548 - 3940 (4635)
(6 hsp)		 0.0 1910   50% NlmA6 nlmA6 Streptomyces nanchangensis
83
 Q7WTD6_9ACTO
(Q7WTD6)		 Jump to Nanch_00270 
[query] 3 - 2383 (3201)
[subject] 10 - 2490 (3455)
(4 hsp)		 0.0 1909   49% NanA8 nanA8 Streptomyces nanchangensis
84
 C6WNU8_ACTMD
(C6WNU8)		 
[query] 8 - 2920 (3201)
[subject] 3 - 3021 (3092)
(3 hsp)		 0.0 1905   44% Short-chain dehydrogenase/reductase SDR Amir_2682 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
85
 E4NJF2_KITSK
(E4NJF2)		 
[query] 7 - 2383 (3201)
[subject] 1 - 2475 (5004)
(8 hsp)		 0.0 1902   50% Modular polyketide synthase BFAS2 bfmA2
KSE_73450		 Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
86
 E0KBI6_STRVO
(E0KBI6)		 
[query] 7 - 2383 (3201)
[subject] 1 - 2490 (4996)
(8 hsp)		 0.0 1901   47% Acyl transferase StrviDRAFT_0201 Streptomyces violaceusniger Tu 4113
87
 D7BSM1_STRBB
(D7BSM1)		 
[query] 9 - 2383 (3201)
[subject] 5 - 2474 (3439)
(4 hsp)		 0.0 1896   49% Type I polyketide synthase nanA8
SBI_08400		 Streptomyces bingchenggensis (strain BCW-1)
88
 B6CLY1_9MYCO
(B6CLY1)		 
[query] 36 - 2920 (3201)
[subject] 1805 - 4870 (12352)
(17 hsp)		 0.0 1891   41% Type I modular polyketide synthase, MlsB mlsB
MULP_051		 Mycobacterium liflandii 128FXT
89
 Q93HJ4_STRAW
(Q93HJ4)		 Jump to Oligo_00090 
[query] 7 - 2920 (3201)
[subject] 1 - 3009 (4840)
(5 hsp)		 0.0 1886   44% Modular polyketide synthase
OlmA2 protein		 olmA2
SAV2898
SAV_2898		 Streptomyces avermitilis
90
 D9W5P0_9ACTO
(D9W5P0)		 
[query] 5 - 2385 (3201)
[subject] 2 - 2466 (3748)
(5 hsp)		 0.0 1884   49% Modular polyketide synthase SSNG_07470 Streptomyces sp. C
91
 A0ACH1_STRAM
(A0ACH1)		 
[query] 39 - 2920 (3201)
[subject] 3590 - 6566 (8154)
(7 hsp)		 0.0 1883   43% Putative polyketide synthase B SAMR0465 Streptomyces ambofaciens ATCC 23877
92
 E9LIP5_9ACTO
(E9LIP5)		 
[query] 8 - 2385 (3201)
[subject] 14 - 2399 (3205)
(5 hsp)		 0.0 1880   48% Putative modular polyketide synthase tiaA2 Dactylosporangium aurantiacum subsp. hamdenensis
93
 D9T6W1_MICAI
(D9T6W1)		 
[query] 39 - 2908 (3201)
[subject] 1774 - 4797 (6415)
(6 hsp)		 0.0 1878   44% Beta-ketoacyl synthase Micau_2461 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
94
 Q8KPW3_9ACTO
(Q8KPW3)		 
[query] 20 - 2382 (3201)
[subject] 1 - 2381 (3734)
(5 hsp)		 0.0 1873   49% Putative type I polyketide synthase gerSIII Streptomyces sp. KCTC 0041BP
95
 Q52V44_9ACTO
(Q52V44)		 
[query] 40 - 2927 (3201)
[subject] 1831 - 4865 (6751)
(8 hsp)		 0.0 1873   44% Polyketide synthase type I Streptomyces aizunensis
96
 A1YAM9_AMYOR
(A1YAM9)		 
[query] 7 - 2388 (3201)
[subject] 2 - 2388 (3264)
(4 hsp)		 0.0 1872   49% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
97
 E4NJF4_KITSK
(E4NJF4)		 
[query] 12 - 2471 (3201)
[subject] 1 - 2575 (3436)
(4 hsp)		 0.0 1872   49% Modular polyketide synthase BFAS4 bfmA4
KSE_73470		 Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
98
 D7C2C2_STRBB
(D7C2C2)		 
[query] 39 - 2920 (3201)
[subject] 154 - 3210 (4821)
(4 hsp)		 0.0 1870   44% Modular polyketide synthase pks3-3
SBI_00655		 Streptomyces bingchenggensis (strain BCW-1)
99
 A4F7P0_SACEN
(A4F7P0)		 
[query] 7 - 2385 (3201)
[subject] 1 - 2361 (3567)
(4 hsp)		 0.0 1870   48% EryAII Erythromycin polyketide synthase modules 3 and 4 eryAII
SACE_0723		 Saccharopolyspora erythraea (strain NRRL 23338)
100
 Q5UNP5_SACER
(Q5UNP5)		 
[query] 7 - 2385 (3201)
[subject] 1 - 2361 (3567)
(4 hsp)		 0.0 1870   48% EryAII eryAII Saccharopolyspora erythraea
Streptomyces erythraeus
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 Q9F828_9ACTO
(Q9F828)		 
[query] 1 - 3201 (3201)
[subject] 1 - 3201 (3201)
 0.0 6249   100%
Product
Megalomicin 6-deoxyerythronolide B synthase 3
Gene
megAIII
Organism
Micromonospora megalomicea subsp. nigra
1uniprot[Pubmed] 10972798 [Medline] 20430101
Biosynthesis of the anti-parasitic agent megalomicin: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea.(Mol. Microbiol.) [2000]
2
 A4F7P1_SACEN
(A4F7P1)		 
[query] 1 - 3198 (3201)
[subject] 1 - 3168 (3171)
 0.0 4573   75%
Product
EryAIII Erythromycin polyketide synthase modules 5 and 6
Gene
eryAIII
SACE_0724
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
3
 Q5UNP4_SACER
(Q5UNP4)		 
[query] 1 - 3198 (3201)
[subject] 1 - 3168 (3171)
 0.0 4573   75%
Product
EryAIII
Gene
eryAIII
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 15496466
Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
2uniprot[Pubmed] 16844787
The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase.(Proc. Natl. Acad. Sci. U.S.A.) [2006]
[pubmed all]
4
 ERYA3_SACER
(Q03133)		 
[query] 1 - 3198 (3201)
[subject] 1 - 3169 (3172)
 0.0 4408   74%
Product
Erythronolide synthase, modules 5 and 6
6-deoxyerythronolide B synthase III
DEBS 3
ORF 3
Gene
eryA
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 2234082 [Medline] 91043075
An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea.(Nature) [1990]
2uniprot[Pubmed] 2024119 [Medline] 91220065
Modular organization of genes required for complex polyketide biosynthesis.(Science) [1991]
3uniprot[Pubmed] 1740151 [Medline] 92155230
6-deoxyerythronolide-B synthase 2 from Saccharopolyspora erythraea. Cloning of the structural gene, sequence analysis and inferred domain structure of the multifunctional enzyme.(Eur. J. Biochem.) [1992]
4uniprot[Pubmed] 1618327
Identification of DEBS 1, DEBS 2 and DEBS 3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase from Saccharopolyspora erythraea.(FEBS Lett.) [1992]
5uniprot[Pubmed] 11752428
Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: versatility from a unique substrate channel.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
6uniprot[Pubmed] 12379102
Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases.(Biochemistry) [2002]
[pubmed all]
5
 Q83X71_STRRO
(Q83X71)		 
[query] 10 - 3199 (3201)
[subject] 22 - 3294 (3295)
 0.0 3382   60%
Product
Lankamycin synthase LkmAIII
Gene
lkmAIII
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
6
 Q5Y9G6_9ACTO
(Q5Y9G6)		 
[query] 9 - 3195 (3201)
[subject] 2 - 3191 (3195)
 0.0 3121   59%
Product
Polyketide synthase modules 5 and 6
Gene
eryAIII
Organism
Aeromicrobium erythreum
1uniprot[Pubmed] 15257441
The erythromycin biosynthetic gene cluster of Aeromicrobium erythreum.(J. Ind. Microbiol. Biotechnol.) [2004]
7
 Q9F830_9ACTO
(Q9F830)		 Jump to Megalo_00120 
[query] 34 - 2920 (3201)
[subject] 552 - 3465 (3546)
(4 hsp)		 0.0 2589   57%
Product
Megalomicin 6-deoxyerythronolide B synthase 1
Gene
megAI
Organism
Micromonospora megalomicea subsp. nigra
1uniprot[Pubmed] 10972798 [Medline] 20430101
Biosynthesis of the anti-parasitic agent megalomicin: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea.(Mol. Microbiol.) [2000]
8
 ERYA1_SACER
(Q03131)		 
[query] 18 - 2920 (3201)
[subject] 477 - 3407 (3491)
(4 hsp)		 0.0 2496   52%
Product
Erythronolide synthase, modules 1 and 2
6-deoxyerythronolide B synthase I
DEBS 1
ORF 1
Gene
eryA
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 2024119 [Medline] 91220065
Modular organization of genes required for complex polyketide biosynthesis.(Science) [1991]
2uniprot[Pubmed] 8386127 [Medline] 93231529
IS1136, an insertion element in the erythromycin gene cluster of Saccharopolyspora erythraea.(Gene) [1993]
[pubmed all]
9
 A4F7N8_SACEN
(A4F7N8)		 
[query] 18 - 2920 (3201)
[subject] 530 - 3461 (3545)
(4 hsp)		 0.0 2494   53%
Product
EryAI Erythromycin polyketide synthase modules 1 and 2
Gene
eryAI
SACE_0721
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
10
 Q5UNP6_SACER
(Q5UNP6)		 
[query] 18 - 2920 (3201)
[subject] 530 - 3461 (3545)
(4 hsp)		 0.0 2494   53%
Product
EryAI
Gene
eryAI
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 15496466
Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
11
 Q3S869_9ACTO
(Q3S869)		 Jump to Conca_00080 
[query] 5 - 2916 (3201)
[subject] 2 - 3171 (5006)
(6 hsp)		 0.0 2304   48%
Product
Modular polyketide synthase
Gene
 
Organism
Streptomyces neyagawaensis
1uniprot[Pubmed] 16207901
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005]
13
 C9YYI3_STRSW
(C9YYI3)		 
[query] 5 - 2916 (3201)
[subject] 2 - 3172 (5001)
(5 hsp)		 0.0 2296   48%
Product
Putative type I polyketide synthase
Gene
SCAB_83921
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
14
 Q9KIV4_STRAT
(Q9KIV4)		 
[query] 39 - 2920 (3201)
[subject] 1062 - 4065 (4150)
(5 hsp)		 0.0 2289   50%
Product
8,8a-deoxyoleandolide synthase 1
Gene
oleAI
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 10908114 [Medline] 20363406
Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin.(J. Antibiot.) [2000]
15
 B1W487_STRGG
(B1W487)		 
[query] 8 - 2916 (3201)
[subject] 4 - 3096 (3188)
(2 hsp)		 0.0 2268   47%
Product
Putative type-I PKS
Gene
pks1-3
SGR_6075
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
16
 Q83X69_STRRO
(Q83X69)		 
[query] 39 - 2940 (3201)
[subject] 588 - 3575 (3651)
(4 hsp)		 0.0 2263   51%
Product
Lankamycin synthase LkmAI
Gene
lkmAI
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
17
 Q93HJ2_STRAW
(Q93HJ2)		 Jump to Oligo_00110 
[query] 16 - 2926 (3201)
[subject] 12 - 3074 (4685)
(6 hsp)		 0.0 2236   48%
Product
Modular polyketide synthase
Gene
olmA6
SAV2896
SAV_2896
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
19
 Q93H83_STRAW
(Q93H83)		 
[query] 9 - 3197 (3201)
[subject] 5 - 3334 (3352)
 0.0 2210   45%
Product
Modular polyketide synthase
Gene
pteA5
SAV415
SAV_415
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
20
 D2CKM3_PSEAH
(D2CKM3)		 
[query] 1 - 2920 (3201)
[subject] 1 - 3087 (3175)
(3 hsp)		 0.0 2196   48%
Product
CppB
Gene
cppB
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
24
 Q53840_SORCE
(Q53840)		 Jump to Soraph_00080 
[query] 37 - 2920 (3201)
[subject] 3669 - 6756 (8817)
(9 hsp)		 0.0 2155   45%
Product
Soraphen polyketide synthase B
Gene
sorB
Organism
Sorangium cellulosum
Polyangium cellulosum
1uniprot[Pubmed] 7601830 [Medline] 95325306
A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes.(J. Bacteriol.) [1995]
2uniprot[Pubmed] 12039053 [Medline] 22035375
Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.(Gene) [2002]
[pubmed all]
25
 A0ACI0_STRAM
(A0ACI0)		 
[query] 39 - 3196 (3201)
[subject] 3064 - 6328 (6333)
(4 hsp)		 0.0 2123   44%
Product
Putative modular polyketide synthase
Gene
SAMR0474
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
26
 Q1WEK7_9ACTO
(Q1WEK7)		 
[query] 39 - 2926 (3201)
[subject] 2954 - 5936 (7968)
(5 hsp)		 0.0 2120   47%
Product
Polyketide synthase
Gene
merC
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
27
 Q9ALM4_9PSEU
(Q9ALM4)		 Jump to Spino_00190 
[query] 8 - 2970 (3201)
[subject] 3 - 3141 (3170)
 0.0 2117   46%
Product
Polyketide synthase extender modules 3-4
Gene
spnC
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
28
 F1CLA9_9ACTO
(F1CLA9)		 
[query] 39 - 2932 (3201)
[subject] 3324 - 6390 (9498)
(9 hsp)		 0.0 2116   46%
Product
ScnS2
Gene
scnS2
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
30
 Q5Y9G4_9ACTO
(Q5Y9G4)		 
[query] 39 - 2922 (3201)
[subject] 512 - 3433 (3528)
(4 hsp)		 0.0 2104   50%
Product
Polyketide synthase modules 1 and 2
Gene
eryAI
Organism
Aeromicrobium erythreum
1uniprot[Pubmed] 15257441
The erythromycin biosynthetic gene cluster of Aeromicrobium erythreum.(J. Ind. Microbiol. Biotechnol.) [2004]
31
 Q68BG5_STRHA
(Q68BG5)		 Jump to Halsto_00010 
[query] 39 - 2983 (3201)
[subject] 1020 - 4179 (4194)
(6 hsp)		 0.0 2101   44%
Product
Type I polyketide synthase
Gene
hlsA
Organism
Streptomyces halstedii
1uniprot
Genome-inspired search for new antibiotics; Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34.(Tetrahedron) [2004]
33
 D3Y1I3_9ACTO
(D3Y1I3)		 
[query] 37 - 2916 (3201)
[subject] 1022 - 3996 (5828)
(8 hsp)		 0.0 2097   45%
Product
TamAI
Gene
 
Organism
Streptomyces sp. 307-9
1uniprot[Pubmed] 20127927
Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010]
34
 Q9EWA1_9ACTO
(Q9EWA1)		 Jump to Pimar_00070 
[query] 39 - 2920 (3201)
[subject] 3332 - 6382 (9507)
(10 hsp)		 0.0 2097   46%
Product
PimS2 protein
Gene
pimS2
Organism
Streptomyces natalensis
1uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
35
 F1DI31_9ACTO
(F1DI31)		 
[query] 37 - 2916 (3201)
[subject] 1022 - 3997 (5829)
(8 hsp)		 0.0 2086   45%
Product
TrdAI
Gene
 
Organism
Streptomyces sp. SCSIO1666
1uniprot[Pubmed] 21329667
Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011]
36
 D1GLV9_9ACTO
(D1GLV9)		 Jump to Strply_00310 
[query] 39 - 2916 (3201)
[subject] 1069 - 4165 (6171)
(9 hsp)		 0.0 2085   46%
Product
Polyketide synthase type I
Gene
slgA1
Organism
Streptomyces lydicus
1uniprot
Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009]
37
 D7P614_CHOCO
(D7P614)		 
[query] 38 - 2920 (3201)
[subject] 16 - 3110 (6610)
(6 hsp)		 0.0 2076   44%
Product
TugD
Gene
tugD
Organism
Chondromyces crocatus
1uniprot[Pubmed] 20416506
Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010]
38
 D7BRE1_STRBB
(D7BRE1)		 
[query] 39 - 2920 (3201)
[subject] 1975 - 5043 (5139)
(5 hsp)		 0.0 2064   45%
Product
Modular polyketide synthase
Gene
SBI_01983
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
39
 Q93NX9_9ACTO
(Q93NX9)		 Jump to Amph_00040 
[query] 37 - 2920 (3201)
[subject] 1770 - 4834 (9510)
(11 hsp)		 0.0 2040   44%
Product
AmphI
Gene
amphI
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
42
 A0FCL3_STRVO
(A0FCL3)		 Jump to Merid_00040 
[query] 37 - 2926 (3201)
[subject] 2948 - 5938 (11604)
(11 hsp)		 0.0 2026   46%
Product
MerC
Gene
merC
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
44
 C9YYI1_STRSW
(C9YYI1)		 
[query] 9 - 2386 (3201)
[subject] 4 - 2464 (4970)
(7 hsp)		 0.0 2023   51%
Product
Putative type I polyketide synthase
Gene
SCAB_83901
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
45
 E0D202_9ACTO
(E0D202)		 Jump to FD891_00010 
[query] 39 - 2393 (3201)
[subject] 1038 - 3425 (7480)
(10 hsp)		 0.0 2018   51%
Product
Polyketide synthase
Gene
gfsA
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
46
 Q9L4X3_9ACTO
(Q9L4X3)		 Jump to Nysta_00050 
[query] 37 - 2920 (3201)
[subject] 1811 - 4879 (9477)
(10 hsp)		 0.0 2017   45%
Product
NysI
Gene
nysI
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
49
 Q3S864_9ACTO
(Q3S864)		 Jump to Conca_00060 
[query] 9 - 2383 (3201)
[subject] 4 - 2457 (4970)
(6 hsp)		 0.0 2011   51%
Product
Nodular polyketide synthase
Gene
 
Organism
Streptomyces neyagawaensis
1uniprot[Pubmed] 16207901
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005]
50
 A4F5C7_SORCE
(A4F5C7)		 
[query] 16 - 2930 (3201)
[subject] 1 - 3127 (5005)
(5 hsp)		 0.0 2003   44%
Product
Polyketide synthase
Gene
spiH
Organism
Sorangium cellulosum
Polyangium cellulosum
1uniprot[Pubmed] 17317575
Spiroketal polyketide formation in Sorangium: Identification of the biosynthetic gene cluster for the highly cytotoxic spirangienes.(Chem. Biol.) [2007]
51
 Q9L4W4_9ACTO
(Q9L4W4)		 Jump to Nysta_00140 
[query] 9 - 2382 (3201)
[subject] 12 - 2464 (3192)
(4 hsp)		 0.0 1998   50%
Product
NysB
Gene
nysB
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
52
 Q3S865_9ACTO
(Q3S865)		 Jump to Conca_00050 
[query] 39 - 2926 (3201)
[subject] 58 - 3194 (4825)
(4 hsp)		 0.0 1988   46%
Product
Modular polyketide synthase
Gene
 
Organism
Streptomyces neyagawaensis
1uniprot[Pubmed] 16207901
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005]
53
 A0FCL2_STRVO
(A0FCL2)		 Jump to Merid_00030 
[query] 37 - 2385 (3201)
[subject] 1732 - 4191 (7178)
(10 hsp)		 0.0 1988   49%
Product
MerB
Gene
merB
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
54
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 37 - 2385 (3201)
[subject] 1727 - 4144 (7102)
(9 hsp)		 0.0 1983   49%
Product
Polyketide synthase
Gene
merB
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
56
 A0FCL1_STRVO
(A0FCL1)		 Jump to Merid_00020 
[query] 39 - 2437 (3201)
[subject] 1067 - 3437 (5721)
(8 hsp)		 0.0 1981   50%
Product
MerA
Gene
merA
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
57
 D7P5Z5_SORCE
(D7P5Z5)		 
[query] 46 - 2917 (3201)
[subject] 1 - 3165 (6663)
(7 hsp)		 0.0 1973   45%
Product
TgaC
Gene
tgaC
Organism
Sorangium cellulosum
Polyangium cellulosum
1uniprot[Pubmed] 20416506
Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010]
58
 D1GLV8_9ACTO
(D1GLV8)		 Jump to Strply_00300 
[query] 7 - 2383 (3201)
[subject] 19 - 2537 (3479)
(4 hsp)		 0.0 1972   50%
Product
Polyketide synthase type I
Gene
slgA2
Organism
Streptomyces lydicus
1uniprot
Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009]
59
 D6C474_9ACTO
(D6C474)		 Jump to Meili_00270 
[query] 8 - 2936 (3201)
[subject] 5 - 3088 (5277)
(4 hsp)		 0.0 1966   44%
Product
Modular polyketide synthase
Gene
meiA4
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
60
 Q5SFB4_STRBI
(Q5SFB4)		 Jump to Chalc_00210 
[query] 39 - 2382 (3201)
[subject] 1063 - 3435 (4441)
(6 hsp)		 0.0 1964   51%
Product
Polyketide synthase subunit
Gene
chmGI
Organism
Streptomyces bikiniensis
1uniprot[Pubmed] 15561847
Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.(Antimicrob. Agents Chemother.) [2004]
61
 C9YYI0_STRSW
(C9YYI0)		 
[query] 39 - 2928 (3201)
[subject] 27 - 3177 (4799)
(4 hsp)		 0.0 1964   46%
Product
Putative type I polyketide synthase
Gene
SCAB_83891
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
63
 F1DI32_9ACTO
(F1DI32)		 
[query] 4 - 2386 (3201)
[subject] 11 - 2469 (3378)
(5 hsp)		 0.0 1961   48%
Product
TrdAII
Gene
 
Organism
Streptomyces sp. SCSIO1666
1uniprot[Pubmed] 21329667
Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011]
64
 Q93H84_STRAW
(Q93H84)		 
[query] 39 - 2920 (3201)
[subject] 1543 - 4556 (6145)
(6 hsp)		 0.0 1959   45%
Product
Modular polyketide synthase
Gene
pteA4
SAV416
SAV_416
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
65
 Q1WEK9_9ACTO
(Q1WEK9)		 
[query] 39 - 2437 (3201)
[subject] 1061 - 3433 (5712)
(8 hsp)		 0.0 1959   51%
Product
Polyketide synthase
Gene
merA
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
66
 Q93NW7_9ACTO
(Q93NW7)		 Jump to Amph_00160 
[query] 1 - 2388 (3201)
[subject] 1 - 2468 (3190)
(4 hsp)		 0.0 1955   48%
Product
AmphB
Gene
amphB
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
3uniprot[Pubmed] 20696392
Structural and functional analysis of A-type ketoreductases from the amphotericin modular polyketide synthase.(Structure) [2010]
[pubmed all]
68
 D7C2C3_STRBB
(D7C2C3)		 
[query] 37 - 2823 (3201)
[subject] 1869 - 4850 (4868)
(5 hsp)		 0.0 1952   45%
Product
Modular polyketide synthase
Gene
pks3-4
SBI_00656
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
69
 D3Y1I4_9ACTO
(D3Y1I4)		 
[query] 7 - 2386 (3201)
[subject] 1 - 2456 (3365)
(5 hsp)		 0.0 1950   48%
Product
TamAII
Gene
 
Organism
Streptomyces sp. 307-9
1uniprot[Pubmed] 20127927
Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010]
70
 Q8KPW5_9ACTO
(Q8KPW5)		 
[query] 39 - 2418 (3201)
[subject] 1008 - 3420 (4387)
(7 hsp)		 0.0 1938   50%
Product
Putative type I polyketide synthase
Gene
gerSI
Organism
Streptomyces sp. KCTC 0041BP
1uniprot[Pubmed] 17053005
Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007]
2uniprot
Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006]
74
 Q9KIV3_STRAT
(Q9KIV3)		 
[query] 7 - 2388 (3201)
[subject] 1 - 2478 (3816)
(4 hsp)		 0.0 1934   49%
Product
8,8a-deoxyoleandolide synthase 2
Gene
oleAII
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 10908114 [Medline] 20363406
Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin.(J. Antibiot.) [2000]
76
 E2Q518_STRCL
(E2Q518)		 
[query] 2 - 2388 (3201)
[subject] 10 - 2590 (3596)
(4 hsp)		 0.0 1927   48%
Product
Modular polyketide synthase
Gene
SCLAV_0012
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
77
 Q6W5P9_9ACTO
(Q6W5P9)		 Jump to FR008_00170 
[query] 8 - 2382 (3201)
[subject] 3 - 2486 (5541)
(8 hsp)		 0.0 1924   49%
Product
FscB
Gene
fscB
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
78
 Q5SFB2_STRBI
(Q5SFB2)		 Jump to Chalc_00230 
[query] 2 - 2382 (3201)
[subject] 3 - 2415 (3788)
(5 hsp)		 0.0 1922   50%
Product
Polyketide synthase subunit
Gene
chmGIII
Organism
Streptomyces bikiniensis
1uniprot[Pubmed] 15561847
Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.(Antimicrob. Agents Chemother.) [2004]
80
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 36 - 2920 (3201)
[subject] 1814 - 4875 (14130)
(19 hsp)		 0.0 1914   41%
Product
Type I modular polyketide synthase
Gene
mlsB
MUP032c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
2uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
[pubmed all]
83
 Q7WTD6_9ACTO
(Q7WTD6)		 Jump to Nanch_00270 
[query] 3 - 2383 (3201)
[subject] 10 - 2490 (3455)
(4 hsp)		 0.0 1909   49%
Product
NanA8
Gene
nanA8
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12770825 [Medline] 22654646
A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin.(Chem. Biol.) [2003]
84
 C6WNU8_ACTMD
(C6WNU8)		 
[query] 8 - 2920 (3201)
[subject] 3 - 3021 (3092)
(3 hsp)		 0.0 1905   44%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2682
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
85
 E4NJF2_KITSK
(E4NJF2)		 
[query] 7 - 2383 (3201)
[subject] 1 - 2475 (5004)
(8 hsp)		 0.0 1902   50%
Product
Modular polyketide synthase BFAS2
Gene
bfmA2
KSE_73450
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
87
 D7BSM1_STRBB
(D7BSM1)		 
[query] 9 - 2383 (3201)
[subject] 5 - 2474 (3439)
(4 hsp)		 0.0 1896   49%
Product
Type I polyketide synthase
Gene
nanA8
SBI_08400
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
88
 B6CLY1_9MYCO
(B6CLY1)		 
[query] 36 - 2920 (3201)
[subject] 1805 - 4870 (12352)
(17 hsp)		 0.0 1891   41%
Product
Type I modular polyketide synthase, MlsB
Gene
mlsB
MULP_051
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
89
 Q93HJ4_STRAW
(Q93HJ4)		 Jump to Oligo_00090 
[query] 7 - 2920 (3201)
[subject] 1 - 3009 (4840)
(5 hsp)		 0.0 1886   44%
Product
Modular polyketide synthase
OlmA2 protein
Gene
olmA2
SAV2898
SAV_2898
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
91
 A0ACH1_STRAM
(A0ACH1)		 
[query] 39 - 2920 (3201)
[subject] 3590 - 6566 (8154)
(7 hsp)		 0.0 1883   43%
Product
Putative polyketide synthase B
Gene
SAMR0465
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
92
 E9LIP5_9ACTO
(E9LIP5)		 
[query] 8 - 2385 (3201)
[subject] 14 - 2399 (3205)
(5 hsp)		 0.0 1880   48%
Product
Putative modular polyketide synthase
Gene
tiaA2
Organism
Dactylosporangium aurantiacum subsp. hamdenensis
1uniprot[Pubmed] 21186805
Characterization of tiacumicin B biosynthetic gene cluster affording diversified tiacumicin analogues and revealing a tailoring dihalogenase.(J. Am. Chem. Soc.) [2011]
94
 Q8KPW3_9ACTO
(Q8KPW3)		 
[query] 20 - 2382 (3201)
[subject] 1 - 2381 (3734)
(5 hsp)		 0.0 1873   49%
Product
Putative type I polyketide synthase
Gene
gerSIII
Organism
Streptomyces sp. KCTC 0041BP
1uniprot[Pubmed] 17053005
Biosynthesis of dTDP-6-deoxy-beta-D-allose, biochemical characterization of dTDP-4-keto-6-deoxyglucose reductase (GerKI) from Streptomyces sp. KCTC 0041BP.(Glycobiology) [2007]
2uniprot
Cloning and characterization of a gene cluster for the production of the polyketide macrolide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP.(J. Microbiol. Biotechnol.) [2006]
95
 Q52V44_9ACTO
(Q52V44)		 
[query] 40 - 2927 (3201)
[subject] 1831 - 4865 (6751)
(8 hsp)		 0.0 1873   44%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
96
 A1YAM9_AMYOR
(A1YAM9)		 
[query] 7 - 2388 (3201)
[subject] 2 - 2388 (3264)
(4 hsp)		 0.0 1872   49%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
97
 E4NJF4_KITSK
(E4NJF4)		 
[query] 12 - 2471 (3201)
[subject] 1 - 2575 (3436)
(4 hsp)		 0.0 1872   49%
Product
Modular polyketide synthase BFAS4
Gene
bfmA4
KSE_73470
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
98
 D7C2C2_STRBB
(D7C2C2)		 
[query] 39 - 2920 (3201)
[subject] 154 - 3210 (4821)
(4 hsp)		 0.0 1870   44%
Product
Modular polyketide synthase
Gene
pks3-3
SBI_00655
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
99
 A4F7P0_SACEN
(A4F7P0)		 
[query] 7 - 2385 (3201)
[subject] 1 - 2361 (3567)
(4 hsp)		 0.0 1870   48%
Product
EryAII Erythromycin polyketide synthase modules 3 and 4
Gene
eryAII
SACE_0723
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
2uniprot[Pubmed] 17719492
Structural and mechanistic analysis of protein interactions in module 3 of the 6-deoxyerythronolide B synthase.(Chem. Biol.) [2007]
[pubmed all]
100
 Q5UNP5_SACER
(Q5UNP5)		 
[query] 7 - 2385 (3201)
[subject] 1 - 2361 (3567)
(4 hsp)		 0.0 1870   48%
Product
EryAII
Gene
eryAII
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 15496466
Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2004]